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CARBAGLU 200 mg DISPERSIBLE TABLETS

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5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use CARBAGLU 200 mg DISPERSIBLE TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet:Information for the User

Carbaglu 200 mg dispersible tablets

carglumic acid

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet:

  1. What is Carbaglu and what is it used for
  2. What you need to know before you take Carbaglu
  3. How to take Carbaglu
  4. Possible side effects

5 Storage of Carbaglu

  1. Contents of the pack and other information

1. What is Carbaglu and what is it used for

Carbaglu can help eliminate excessive plasma ammonia levels (high ammonia levels in the blood). Ammonia is especially toxic to the brain and can cause, in severe cases, a decrease in the level of consciousness and coma.

Hyperammonemia can be due to

  • the lack of a specific hepatic enzyme, N-acetylglutamate synthase. Patients with this rare disorder are unable to eliminate nitrogen waste, which increases after eating proteins.

This disorder persists throughout the patient's life, so this treatment is necessary for life.

  • isovaleric acidemia, methylmalonic acidemia, or propionic acidemia. Patients who suffer from one of these disorders need treatment during the hyperammonemia crisis.
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Carbaglu

Donottake Carbaglu:

Do not take Carbaglu if you are allergic (hypersensitive) to carglumic acid or any of the other ingredients of Carbaglu (listed in section 6).

Do not take Carbaglu during breastfeeding.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Carbaglu.

Treatment with Carbaglu should be initiated under the supervision of a doctor with experience in the treatment of metabolic disorders.

Your doctor will assess your individual response to carglumic acid before starting any long-term treatment.

The dose should be adjusted individually to maintain normal ammonia levels in the blood.

Your doctor may prescribe arginine supplements or limit your protein intake.

In order to monitor your disease and treatment, your doctor may periodically examine your liver, kidneys, heart, and blood.

Other medicines and Carbaglu

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Using Carbaglu with food and drinks

Carbaglu should be taken orally before main meals or food intake.

The tablets should be dispersed in a minimum of 5 to 10 ml of water and taken immediately. The suspension has a slightly acidic taste.

Pregnancy and breastfeeding

The effects of Carbaglu on pregnancy and the fetus are unknown.

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

The effects on the ability to drive and use machines are unknown.

3. How to take Carbaglu

Follow exactly the administration instructions of this medicine given by your doctor. If you are unsure, consult your doctor or pharmacist again.

Usual dose:

The initial daily dose is usually 100 mg per kilogram of body weight, up to a maximum of 250 mg per kilogram of body weight (for example, if you weigh 10 kg, you should take 1 g per day, or 5 tablets). For patients with N-acetylglutamate synthase deficiency, the long-term daily dose usually ranges from 10 mg to 100 mg per kilogram of body weight.

Your doctor will determine the suitable dose for you to maintain normal ammonia levels in your blood.

Carbaglu should be administered ONLYorally or through a nasogastric tube (using a syringe if necessary).

When the patient is in hyperammonemic coma, Carbaglu is administered by rapid push with a syringe through the tube used for feeding.

Tell your doctor if you have kidney impairment. Your daily dose should be reduced.

If you take more Carbaglu than you should

Consult your doctor or pharmacist.

If you forget to take Carbaglu

Do not take a double dose to make up for forgotten doses.

If you stop taking Carbaglu:

Do not stop taking Carbaglu without informing your doctor.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported: very common (may affect more than 1 in 10 people), common (may affect up to 1 in 10 people), uncommon (may affect up to 1 in 100 people), rare (may affect up to 1 in 1,000 people), very rare (may affect up to 1 in 10,000 people), and not known (cannot be estimated from the available data).

  • Common:increased sweating
  • Uncommon:bradycardia (decreased heart rate), diarrhea, fever, increased aminotransferases, vomiting.
  • Not known:rash

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Carbaglu

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP.

The expiry date is the last day of the month stated.

Store in a refrigerator (between 2°C and 8°C).

After opening the tablet container for the first time: do not refrigerate. Do not store above 30°C.

Keep the container tightly closed to protect from moisture.

Write the opening date on the tablet container. Discard 3 months after first opening.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

Composition of Carbaglu

  • The active substance is carglumic acid. Each tablet contains 200 mg of carglumic acid.
  • The other ingredients are microcrystalline cellulose, sodium lauryl sulfate, hypromellose, sodium croscarmellose, colloidal anhydrous silica, sodium stearyl fumarate.

Appearance and packaging

Carbaglu 200 mg dispersible tablets are bar-shaped tablets with 4 divisions on one side and 3 break marks. Carbaglu is available in plastic containers of 5, 15, and 60 tablets, closed with a child-resistant cap.

Marketing authorisation holder

Recordati Rare Diseases

Immeuble “Le Wilson”

70 avenue du Général de Gaulle

F-92800 Puteaux

France

Tel.: + 33 1 4773 6458

Fax: + 33 1 4900 1800

Manufacturer

Recordati Rare Diseases

Immeuble “Le Wilson”

70, Avenue du Général de Gaulle

F-92800 Puteaux

France

or

Recordati Rare Diseases

Eco River Parc

30, rue des Peupliers

F-92000 Nanterre

France

You can request more information about this medicine from the local representative of the Marketing Authorisation Holder.

Belgium/België/Belgien

Recordati

Tel: +32 2 46101 36

Lithuania

Recordati AB.

Tel: + 46 8 545 80 230

Sweden

Greece

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Luxembourg/Luxemburg

Recordati

Tel: +32 2 46101 36

Belgium

Czech Republic

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Hungary

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Denmark

Recordati AB.

Tel: +46 8 545 80 230

Sweden

Malta

Recordati Rare Diseases

Tel: +33 1 47 73 64 58

France

Germany

Recordati Rare Diseases Germany GmbH

Tel: +49 731 140 554 0

Netherlands

Recordati

Tel: +32 2 46101 36

Belgium

Estonia

Recordati AB.

Tel: + 46 8 545 80 230

Sweden

Norway

Recordati AB.

Tel: +46 8 545 80 230

Sweden

Greece

Recordati Hellas

Tel: +30 210 6773822

Austria

Recordati Rare Diseases Germany GmbH

Tel: +49 731 140 554 0

Germany

Spain

Recordati Rare Diseases Spain S.L.U.

Tel: + 34 91 659 28 90

Poland

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

France

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

Portugal

Jaba Recordati S.A.

Tel: +351 21 432 95 00

Croatia

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Romania

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Ireland

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Slovenia

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Iceland

Recordati AB.

Tel: +46 8 545 80 230

Sweden

Slovakia

Recordati Rare Diseases

Tel: +33 (0)1 47 73 64 58

France

Italy

Recordati Rare Diseases Italy Srl

Tel: +39 02 487 87 173

Finland

Recordati AB.

Tel: +46 8 545 80 230

Sweden

Cyprus

Recordati Rare Diseases

Tel: +33 1 47 73 64 58

France

Sweden

Recordati AB.

Tel: +46 8 545 80 230

Latvia

Recordati AB.

Tel: + 46 8 545 80 230

Sweden

United Kingdom (Northern Ireland)

Recordati Rare Diseases UK Ltd.

Tel: +44 (0)1491 414333

Date of last revision of this leaflet:

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu. There are also links to other websites on rare diseases and treatments.

Online doctors for CARBAGLU 200 mg DISPERSIBLE TABLETS

Discuss questions about CARBAGLU 200 mg DISPERSIBLE TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€86
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
€61

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Frequently Asked Questions

Is a prescription required for CARBAGLU 200 mg DISPERSIBLE TABLETS?

CARBAGLU 200 mg DISPERSIBLE TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in CARBAGLU 200 mg DISPERSIBLE TABLETS?

The active ingredient in CARBAGLU 200 mg DISPERSIBLE TABLETS is carglumic acid. This information helps identify medicines with the same composition but different brand names.

Who manufactures CARBAGLU 200 mg DISPERSIBLE TABLETS?

CARBAGLU 200 mg DISPERSIBLE TABLETS is manufactured by Recordati Rare Diseases. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of CARBAGLU 200 mg DISPERSIBLE TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether CARBAGLU 200 mg DISPERSIBLE TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy CARBAGLU 200 mg DISPERSIBLE TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy CARBAGLU 200 mg DISPERSIBLE TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to CARBAGLU 200 mg DISPERSIBLE TABLETS?

Other medicines with the same active substance (carglumic acid) include CARGLUMIC ACID TILLOMED 200 mg DISPERSIBLE TABLETS, CARGLUMIC ACID WAYMADE 200 mg DISPERSIBLE TABLETS, CARBAGLU 200 mg DISPERSIBLE TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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