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WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE

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About the medicine

How to use WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Water forInjectable PreparationsGrifols Solvent for Parenteral Use

Read the entire package leaflet carefully before starting to use this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or nurse.
  • If you experience side effects, consult your doctor or nurse, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What Water for Injectable Preparations Grifols is and what it is used for
  2. What you need to know before starting to use Water for Injectable Preparations Grifols
  3. How to use Water for Injectable Preparations Grifols
  4. Possible side effects
  5. Storage of Water for Injectable Preparations Grifols
  1. Contents of the Packaging and Additional Information

1. What Water for Injectable Preparations Grifols is and what it is used for

The medication is a solvent for parenteral use used as a vehicle for the administration of medications, which is indicated as:

  • Solvent for powder or lyophilized medications for subsequent administration
  • Diluent for solutions and/or medications.

Given its markedly hypotonic character, Water forInjectable PreparationsGrifols is especially indicated for reconstituting medications and/or diluting hypertonic solutions.

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2. What you need to know before starting to use Water for Injectable Preparations Grifols

The contraindications related to the added medications should be considered.

Warnings and Precautions

Consult your doctor or nurse before starting to use Water for Injectable Preparations Grifols.

The water for injectable preparations is markedly hypotonic (less concentrated than blood) and should not be injected without mixing with medications.Before administering intravenously, it should be checked that the final solution is isotonic with blood.

The administration of large volumes of hypotonic solution can cause hemolysis (destruction of red blood cells). To evaluate the appearance of hemolysis, it is recommended to monitor the hematocrit (percentage of red blood cells in blood), blood levels of hemoglobin, haptoglobin, bilirubin, and lactate dehydrogenase, and to check for hematuria (presence of blood in urine). It is also recommended to check the proper functioning of the kidney through laboratory tests.

When large volumes of this medication are administered, the ionic balance should be frequently checked.

If you are elderly, if your heart, liver, and/or kidneys do not function correctly, or if it is used in children, the complications related to incorrect or uncontrolled use of water for injectable preparations can be more severe.

Use ofWater forInjectable PreparationsGrifols withOther Medications

Tell your doctor if you are using, have recently used, or may need to use any other medication.

The possible interactions of the medications to be dissolved and/or diluted should be considered.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medication.

The risk of using water for injectable preparations during pregnancy and breastfeeding is determined by the added medication.

Driving and Using Machines

The possible effects on the ability to drive and use machinery of the added medications should be considered.

3. How to Use Water for Injectable Preparations Grifols

Water for Injectable Preparations Grifols is a solvent and/or diluent for medications for subsequent parenteral administration.

It will be used in a hospital by the corresponding healthcare personnel.

The dosage of the obtained solution will depend mainly on the added medication and the patient's requirements.

If you are given moreWater forInjectable PreparationsGrifolsthan you should

If large volumes of hypotonic solution are administered when using water for injectable preparations as a diluent, hemolysis may occur.

The signs and symptoms of an overdose may also be related to the added medication.

In case of overdose, administration should be interrupted and symptomatic treatment should be initiated.

If a hemolytic reaction is suspected during the administration of a solution prepared with water for injectable preparations, it should be suspended and a red blood cell concentrate should be administered, diuresis should be induced with diuretics and intravenous fluids, and kidney function and coagulation status should be monitored.

In case of overdose or accidental ingestion, consult the Toxicology Information Service. Phone: 915 620 420.

If you have any other questions about the use of this medication, ask your doctor or nurse.

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4. Possible Side Effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

Side effects associated with the administration technique may occur, including pain or reaction at the injection site, fever, infection, extravasation, venous thrombosis, and phlebitis extending from the injection site, among others.

Its use can cause hemolysis if it is injected without mixing with medications.

The nature of the added medication will determine the likelihood of any other side effect.

In case of side effects, administration of the solution should be interrupted and symptomatic treatment should be initiated.

Reporting Side Effects

If you experience any type of side effect, consult your doctor or nurse, even if it is a possible side effect that is not listed in this package leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use (website: www.notificaRAM.es). By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Water for Injectable Preparations Grifols

Keep this medication out of sight and reach of children.

No special storage conditions are required.

Do not use this medication after the expiration date shown on the packaging. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. In case of doubt, ask your pharmacist how to dispose of the packaging and medications that are no longer needed. This will help protect the environment.

6. Contents of the Packaging and Additional Information

Composition of Water forInjectable PreparationsGrifols

The active ingredient is water for injectable preparations (100%).

Appearance of the Product and Contents of the Packaging

It is a transparent and colorless solvent for parenteral use, which is presented in Type II glass vials of 100, 250, and 500 ml.

Marketing Authorization Holder

LABORATORIOS GRIFOLS, S.A.

Can Guasch, 2

08150 Parets del Vallès, Barcelona (SPAIN)

Manufacturer

LABORATORIOS GRIFOLS, S.A.

Polígono Industrial Autopista. Passeig Fluvial, 24.

08150 Parets del Vallès, Barcelona (SPAIN)

Date of the Last Revision of this Package Leaflet:October 2014

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

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This information is intended only for healthcare professionals:

Administer intravenously.

Once the packaging is opened, the contents should be used immediately. The unused volume should be discarded.

Do not use if the product is not transparent or contains visible particles.

Do not injectWater forInjectable PreparationsGrifols without mixing with medications.

Before adding medications, it should be checked that they are soluble and stable in water for injectable preparations and that they are compatible with each other.

It is recommended to perform the reconstitution and/or dilution of medications in Water for Injectable Preparations Grifols under controlled and validated aseptic conditions, and that the obtained solutions be used immediately after preparation.

When using water for injectable preparations as a solvent for medications and/or diluent for solutions, the osmolarity and tonicity of the final solution should be controlledand adjusted, whenever possible, to its isotonicity with plasma.

Use an aseptic procedure to administer the obtained solution.

Online doctors for WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE

Discuss questions about WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (3)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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€80
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
5.0 (764)
Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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€55
5.0 (140)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50

Frequently Asked Questions

Is a prescription required for WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE?
WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE?
WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE is manufactured by Laboratorios Grifols S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to WATER FOR INJECTABLE PREPARATIONS GRIFOLS SOLVENT FOR PARENTERAL USE?
Other medicines with the same active substance () include WATER FOR INJECTABLE PREPARATIONS B.BRAUN SOLVENT FOR PARENTERAL USE, WATER FOR INJECTABLE PREPARATIONS BEXEN SOLVENT FOR PARENTERAL USE, AGUA PARA PREPARACIONES INYECTABLES FRESENIUS KABI SOLVENT FOR PARENTERAL USE. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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