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YELLOX 0.9 mg/ml EYE DROPS SOLUTION

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About the medicine

How to use YELLOX 0.9 mg/ml EYE DROPS SOLUTION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Yellox 0.9 mg/ml eye drops, solution

Bromfenac

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet:

  1. What is Yellox and what is it used for
  1. What you need to know before you use Yellox
  2. How to use Yellox
  3. Possible side effects
  4. Storage of Yellox
  5. Contents of the pack and other information

1. What is Yellox and what is it used for

Yellox contains bromfenac and belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking certain substances involved in inflammation.

Yellox is used to reduce eye inflammation after cataract surgery in adults.

Doctor consultation

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2. What you need to know before you use Yellox

Do not use Yellox

  • if you are allergic to bromfenac or any of the other ingredients of this medicine (listed in section 6).
  • if you have experienced asthma, skin allergy, or severe nasal inflammation when using other NSAIDs. Examples of NSAIDs include acetylsalicylic acid, ibuprofen, ketoprofen, diclofenac.

Warnings and precautions

Consult your doctor or pharmacist before starting to use Yellox

  • if you are using topical steroids (e.g., cortisone), as this may cause unwanted side effects.
  • if you have bleeding problems (e.g., hemophilia) or have had them in the past, or are taking other medicines that may prolong bleeding time (e.g., warfarin, clopidogrel, acetylsalicylic acid).
  • if you have eye problems (e.g., dry eye syndrome, corneal problems).
  • if you have diabetes.
  • if you have rheumatoid arthritis.
  • if you have had several eye surgeries in a short period of time.

It is not recommended to wear contact lenses after cataract surgery. Therefore, do not use contact lenses while using Yellox.

Children and adolescents

Yellox must not be used in children and adolescents.

Using Yellox with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using Yellox.

Yellox must not be used during the last three months of pregnancy. Your doctor may prescribe this medicine during pregnancy if the expected benefit to the mother outweighs the possible risk to the baby.

Yellox may be prescribed during breastfeeding and has no significant effect on fertility.

Driving and using machines

Your vision may be blurred temporarily when using this eye drop. If you experience blurred vision after instillation, do not drive or use machines until your vision clears.

Yellox contains benzalkonium chloride

This medicine contains 0.00185 mg of benzalkonium chloride per drop, which is equivalent to 0.05 mg/ml.

Benzalkonium chloride may be absorbed by soft contact lenses and may change the color of the contact lenses. Remove contact lenses before using this medicine and wait 15 minutes before putting them back.

Benzalkonium chloride may cause eye irritation, especially if you have dry eye or other corneal diseases (the transparent layer on the front of the eye). Consult your doctor if you feel any unusual sensation, itching, or pain in the eye after using this medicine.

3. How to use Yellox

Medicine questions

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Follow the instructions for administration of this medicine exactly as told by your doctor.

Consult your doctor or pharmacist if you have any questions.

Dose

The recommended dose is one drop of Yellox in the affected eye(s) twice a day (morning and evening). Do not use more than one drop in the affected eye(s) 2 times a day. Start using this eye drop the day after your cataract surgery.

Method of administration

Yellox is administered via the ocular route.

  • Wash your hands before using the eye drop.
  • Place yourself in a comfortable and stable position.
  • Remove the cap from the bottle.
  • Hold the bottle, pointing downwards, between your fingers.
  • Tilt your head back.
  • Pull down the lower eyelid with one finger.
  • Bring the tip of the bottle close to the eye.
  • Do not touch the eye, eyelid, or surrounding areas with the dropper.
  • Gently press the bottle to release one drop of Yellox.
  • Tighten the cap of the bottle immediately after use.
  • Keep the bottle tightly closed when not in use.

If you use other eye drops, wait at least five minutes between using Yellox and the other eye drops.

Duration of treatment

Continue with the drops for the first 2 weeks after surgery. Do not use Yellox for more than 2 weeks.

If you use more Yellox than you should

Rinse your eye with lukewarm water. Do not put in more drops until it is time for your next usual dose.

If Yellox is accidentally ingested, drink a glass of water or other liquids to dilute the medicine.

If you forget to use Yellox

Instill one drop as soon as you remember. If it is almost time for your next dose, skip the missed dose. Continue with your next scheduled dose. Do not take a double dose to make up for the missed one.

If you stop using Yellox

Do not stop using Yellox without talking to your doctor.

In rare cases, after stopping Yellox, a worsening of the inflammatory response has been observed, for example, in the form of retinal swelling due to cataract surgery.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If you experience loss of vision or blurred vision the week after finishing treatment, contact your doctor immediately.

If you notice any of the following side effects while using the eye drop, consult your doctor immediately:

Uncommon side effects (may affect up to 1 in 100 people)

Feeling of a foreign body in the eye, redness and eye inflammation, damage and inflammation of the eye surface, eye discharge, itching, irritation, or eye pain, swelling or bleeding of the eyelid, vision deterioration due to inflammation, "floaters" or moving spots before the eyes, or vision deterioration that may indicate bleeding or injury to the back of the eye (retina), eye discomfort, sensitivity to light, reduced or blurred vision, facial inflammation, cough, nosebleed, or runny nose.

Rare side effects (may affect up to 1 in 1,000 people)

Damage to the eye surface, eye redness, asthma.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Yellox

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after "EXP". The expiry date is the last day of the month shown.

Do not store above 25°C.

Discard the bottle 4 weeks after first opening to avoid infections, even if there is solution left.

Write the date of opening on the label of the outer packaging in the space provided.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

Composition of Yellox

  • The active substance is bromfenac. 1 ml of solution contains 0.9 mg of bromfenac (as sodium sesquihydrate). One drop contains approximately 33 micrograms of bromfenac.
  • The other ingredients are: boric acid, borax, sodium sulfite anhydrous (E221), benzalkonium chloride (see section 2), tyloxapol, povidone (K30), disodium edetate, water for injections, sodium hydroxide to adjust pH levels.

Appearance and packaging of the product

Yellox is a clear yellow liquid (solution) supplied in a carton containing a 5 ml plastic bottle with a screw cap.

Marketing authorisation holder

BAUSCH + LOMB IRELAND LIMITED

3013 Lake Drive

Citywest Business Campus

Dublin 24, D24PPT3

Ireland

Manufacturer

Dr. Gerhard Mann

Chem.-pharm. Fabrik GmbH

Brunsbütteler Damm 165/173

13581 Berlin

Germany

This leaflet was last revised in

Detailed information on this medicine is available on the European Medicines Agency website http://www.ema.europa.eu.

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Discuss questions about YELLOX 0.9 mg/ml EYE DROPS SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

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Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

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General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

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General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

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Frequently Asked Questions

Is a prescription required for YELLOX 0.9 mg/ml EYE DROPS SOLUTION?
YELLOX 0.9 mg/ml EYE DROPS SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in YELLOX 0.9 mg/ml EYE DROPS SOLUTION?
The active ingredient in YELLOX 0.9 mg/ml EYE DROPS SOLUTION is bromfenac. This information helps identify medicines with the same composition but different brand names.
Who manufactures YELLOX 0.9 mg/ml EYE DROPS SOLUTION?
YELLOX 0.9 mg/ml EYE DROPS SOLUTION is manufactured by Bausch + Lomb Ireland Limited. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of YELLOX 0.9 mg/ml EYE DROPS SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether YELLOX 0.9 mg/ml EYE DROPS SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to YELLOX 0.9 mg/ml EYE DROPS SOLUTION?
Other medicines with the same active substance (bromfenac) include ACULAR 5 mg/ml EYE DROPS SOLUTION, DICLOABAK 1 mg/ml EYE DROPS SOLUTION, DICLOFENAC ABAMED 1 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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