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YATROX 8 mg FILM-COATED TABLETS

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use YATROX 8 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Doctor consultation

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Yatrox 8 mg Film-Coated Tablets

ondansetron

Medicine questions

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Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.

If you have any further questions, ask your doctor or pharmacist.

  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Yatrox and what is it used for
  2. What you need to know before you take Yatrox
  3. How to take Yatrox
  4. Possible side effects
  5. Storage of Yatrox
  6. Contents of the pack and other information

1. What is Yatrox and what is it used for

Yatrox belongs to a group of medicines called antiemetics. Yatrox is used to:

  • prevent nausea and vomiting caused by:
    • cancer chemotherapy in adults and children over 6 months of age.
    • radiotherapy in the treatment of cancer in adults.
  • prevent post-operative nausea and vomiting in adults.

2. What you need to know before you take Yatrox

Do not take Yatrox:

  • If you are allergic (hypersensitive) to ondansetron or any of the other ingredients of Yatrox (listed in section 6).
  • If you have had an allergic reaction (hypersensitivity) to other medicines for nausea or vomiting (e.g. granisetron or dolasetron).
  • If you are taking apomorphine (a medicine used to treat Parkinson's disease).

If you think any of these apply to you, talk to your doctor before taking Yatrox.

Warnings and precautions

Talk to your doctor or pharmacist before taking Yatrox.

If you are going to have any diagnostic tests (including blood tests, urine tests, skin tests that use allergens, etc.), tell your doctor that you are taking this medicine, as it may affect the results.

Using Yatrox with other medicines

Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.

In particular, it is important to tell your doctor if you are taking any of the following medicines, as it may be necessary to stop treatment or adjust the dose of one of them:

  • rifampicin (an antibiotic used to treat infections such as tuberculosis).
  • tramadol (a medicine used to treat pain).
  • phenytoin or carbamazepine (medicines used to treat epilepsy).
  • medicines used to treat heart problems such as irregular heartbeat (antiarrhythmics) and/or to treat high blood pressure (beta blockers).
  • haloperidol or methadone (medicines that can affect the heart).
  • anthracyclines and trastuzumab (medicines used to treat cancer).
  • fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram (Selective Serotonin Reuptake Inhibitors, used to treat depression and/or anxiety)
  • venlafaxine, duloxetine (Serotonin and Noradrenaline Reuptake Inhibitors, used to treat depression and/or anxiety).

Tell your doctor or pharmacist if you are taking any of these medicines.

Pregnancy and breastfeeding

Yatrox should not be used during the first trimester of pregnancy. This is because Yatrox may slightly increase the risk of a baby being born with a cleft lip and/or cleft palate. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking Yatrox. If you are a woman of childbearing age, you are advised to use an effective method of birth control.

Driving and using machines

Yatrox is unlikely to affect your ability to drive or use machines.

Yatrox contains lactose

This medicine contains lactose. If your doctor has told you that you have an intolerance to some sugars, contact them before taking this medicine.

3. How to take Yatrox

Always take this medicine exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

Remember to take your medicine. Swallow the tablets whole, with a little water. Your doctor will tell you how long to take Yatrox for. Do not stop treatment early.

Nausea and vomiting caused by chemotherapy or radiotherapy

Adults

One tablet (8 mg) by mouth, 1-2 hours before the medical treatment that may cause nausea and vomiting, and then one tablet (8 mg) 12 hours later.

To prevent nausea and vomiting on subsequent days, continue taking one tablet (8 mg) every 12 hours for five days.

Nausea and vomiting caused by chemotherapy

Children over 6 months and adolescents

Your doctor will decide the dose based on your child's weight or body surface area.

Normally, 12 hours after chemotherapy, your child will receive ondansetron by mouth. The usual dose is 4 mg twice a day and may continue for up to 5 days.

Post-operative nausea and vomiting

Adults

To prevent nausea and vomiting after surgery, 2 tablets (16 mg) by mouth, 1 hour before anesthesia.

Children

There is no data on the oral administration of ondansetron in the prevention of post-operative nausea and vomiting in children.

Dose adjustments

Patient with liver impairment

In patients with liver problems, the dose should be adjusted to a maximum of 8 mg per day of ondansetron.

Elderly patients, patients with renal impairment or poor metabolizers of sparteine/debrisoquine

No dose adjustment is necessary.

Duration of treatment

Your doctor will decide the duration of your treatment with Yatrox. Do not stop treatment early.

If you think the effect of this medicine is too strong or too weak, talk to your doctor or pharmacist.

If you take more Yatrox than you should

In case of overdose, the symptoms that may appear are: vision problems, low blood pressure (which can cause dizziness or fainting) and palpitations (irregular heartbeat).

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Yatrox

Do not take a double dose to make up for forgotten doses. Do not increase or decrease the dose without consulting your doctor.

If you forget to take a dose and have nausea or vomiting, take another dose as soon as possible. Then, continue taking the medicine as directed.

If you forget to take a dose and do not have nausea or vomiting, wait for the next dose and continue taking the medicine as directed.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Yatrox can cause side effects, although not everybody gets them.

Very common side effects

May affect more than 1 in 10 people taking Yatrox:

  • headache

Common side effects

May affect up to 1 in 10 people taking Yatrox:

  • feeling of warmth or flushing
  • constipation

Uncommon side effects

May affect up to 1 in 100 people taking Yatrox:

  • rotating upward movements of the eyes, abnormal muscle stiffness, body movements, tremor
  • seizures
  • slow or irregular heartbeat
  • low blood pressure
  • hypoglycemia
  • increased levels in blood test results for liver function.

Rare side effects

May affect less than 1 in 1,000 people taking Yatrox:

  • sudden onset of wheezing or chest pain or tightness
  • swelling of the eyelids, face, lips, mouth or tongue
  • skin rash or hives anywhere on the body
  • abnormal heart rhythm (which can sometimes cause a sudden loss of consciousness)
  • blurred vision.

If you experience any of these symptoms, stop taking the medicine immediately and contact your doctor.

Very rare side effects

May affect less than 1 in 10,000 people taking Yatrox:

  • temporary blindness, which usually resolves within 20 minutes
  • changes in the electrocardiogram
  • widespread skin rash with blisters and peeling, affecting a large area of the body (Toxic Epidermal Necrolysis).

Inform your doctor immediately if you experience any of these symptoms.

Side effects of unknown frequency: cannot be estimated from the available data

  • Myocardial ischemia

The signs include:

  • sudden chest pain or
  • chest tightness

If you experience side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Yatrox

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and on the carton after EXP. The expiry date is the last day of the month shown.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

What Yatrox contains

The active substance is ondansetron hydrochloride dihydrate. Each film-coated tablet of Yatrox contains 8 mg of ondansetron (as hydrochloride dihydrate).

The other ingredients are: lactose monohydrate, microcrystalline cellulose (E460), pregelatinized maize starch, magnesium stearate (E470b), hypromellose (E464), titanium dioxide (E171) and polyethylene glycol 400 (E1521).

Appearance and packaging

Yatrox 8 mg are white, oblong, biconvex film-coated tablets with the inscription “8” on one side.

Yatrox is available in packs of 6, 15 or 500 tablets.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Dari Pharma, S.L.U.

Gran Via Carles III, 98, 10th floor

08028 Barcelona

Spain

Manufacturer

Neuraxpharm Pharmaceuticals, S.L.

Avda. Barcelona, 69

08970 Sant Joan Despí – Barcelona

Spain

Date of last revision of this leaflet:February 2022

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS): http://www.aemps.gob.es/

Online doctors for YATROX 8 mg FILM-COATED TABLETS

Discuss questions about YATROX 8 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
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She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
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  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
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  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

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Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Frequently Asked Questions

Is a prescription required for YATROX 8 mg FILM-COATED TABLETS?

YATROX 8 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in YATROX 8 mg FILM-COATED TABLETS?

The active ingredient in YATROX 8 mg FILM-COATED TABLETS is ondansetron. This information helps identify medicines with the same composition but different brand names.

Who manufactures YATROX 8 mg FILM-COATED TABLETS?

YATROX 8 mg FILM-COATED TABLETS is manufactured by Dari Pharma S.L.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of YATROX 8 mg FILM-COATED TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether YATROX 8 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy YATROX 8 mg FILM-COATED TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy YATROX 8 mg FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to YATROX 8 mg FILM-COATED TABLETS?

Other medicines with the same active substance (ondansetron) include ONDANSETRON ACCORD 2 mg/ml INJECTABLE SOLUTION, ONDANSETRON ARISTO 4 mg ORALLY DISINTEGRATING TABLETS, ONDANSETRON ARISTO 8 mg ORALLY DISINTEGRATING TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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