Skip to main content

Tosidrin 10 mg/ml gotas orales in solution

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION

Contents of the leaflet

  1. Introduction
  2. What is Tosidrin and what is it used for
  3. What you need to know before taking Tosidrin
  4. How to take Tosidrin
  5. Possible side effects
  6. Storage of Tosidrin
  7. Package contents and additional information

Introduction

Leaflet: Information for the user

Tosidrin 10 mg/ml oral drops in solution

Dihydrocodeine bitartrate

Read this leaflet carefully before starting to take this medication, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this leaflet. See section 4.

Contents of the leaflet:

  1. What is Tosidrin and what is it used for
  2. What you need to know before taking Tosidrin
  3. How to take Tosidrin
  4. Possible side effects
  5. Storage of Tosidrin
  6. Package contents and additional information

1. What is Tosidrin and what is it used for

The dihydrocodeine bitartrate, the active ingredient of Tosidrin, is a substance that calms or relieves cough (antitussive activity).

Tosidrin is indicated for the symptomatic treatment of non-productive cough (without mucus).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Tosidrin

Do not take Tosidrin:

  • If you are allergic to dihydrocodeine or any of the other components of this medication (listed in section 6).
  • Children under 2 years of age
  • If you have respiratory problems (bronchial asthma, pulmonary emphysema, or respiratory depression).
  • If you have seizures
  • If you are in a coma.
  • You are in the third trimester of pregnancy.
  • If you are breastfeeding.

Warnings and precautions

Consult your doctor or pharmacist before starting to take this medication.

It is not recommended for use:

  • in cases of disorders of consciousness and in states of high intracranial pressure.
  • if you are in the first four months of pregnancy.
  • if you have chronic constipation.
  • if you have diarrhea associated with pseudomembranous colitis (inflammation of the colon) caused by antibiotics or in diarrhea caused by poisoning until the toxic material has been eliminated from the gastrointestinal tract.
  • if you have opioid dependence

It should be administered with caution:

Before taking this medication, you should consult your doctor, especially:

  • Elderly patients.
  • If you have liver, heart, or kidney problems.
  • If you have hypothyroidism.
  • If you have prostatic hyperplasia (enlarged prostate), chronic ulcerative colitis (inflammatory disease of the colon or rectum), gallbladder conditions, multiple sclerosis, and diseases that cause decreased respiratory capacity.

Do not take this medication if you know you metabolize codeine or dihydrocodeine very quickly, as there may be a risk of greater side effects.

Prolonged use of this medication is not recommended, as it may cause physical and psychological dependence (addiction).

Children

Consult your doctor if the child has chronic cough, as it may be a symptom of asthma.

Taking Tosidrin with other medications

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medication:

Taking this medication with opioid agonists (narcotics) and other central nervous system depressants (including ethanol) and tricyclic antidepressants and MAO inhibitors may cause additive depression of the central nervous system. As a precaution, it is advisable to leave a 15-day interval after finishing treatment with MAOI and taking this medication.

Other medications that interact with this medication are medications to treat allergies, both first-generation antihistamines (chlorpheniramine) and second-generation antihistamines (cetirizine and ebastine); and calcium antagonists (such as nifedipine and verapamil), and also methysergide, naloxone, and hydroxyzine.

Taking Tosidrin with food, drinks, and alcohol

During treatment, do not consume alcoholic beverages, as they may potentiate the depressant effect on the central nervous system.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

Pregnancy

In the third trimester of pregnancy, it should not be taken, as it may cause harm to the fetus.

Do not take this medication during the first and second trimester of pregnancy, unless your doctor considers it strictly necessary.

Breastfeeding

This medication passes into breast milk. For this reason, it should not be taken during breastfeeding. If treatment with this medication is essential, breastfeeding should be interrupted.

Driving and using machines

This medication may cause drowsiness and may interfere with the ability to drive or operate hazardous machinery. Therefore, driving vehicles and/or operating hazardous machinery should be avoided during treatment. This effect is intensified by the action of alcohol or medications that may also impair reaction capacity.

Use in athletes

This medication contains a component that may produce a positive result in the analytical control of opioids.

Important information about some of the components of Tosidrin

This medication contains 5% v/v ethanol (alcohol), which corresponds to 40.2 mg/ml.

3. How to take Tosidrin

Follow your doctor's instructions for administering this medication exactly. If in doubt, consult your doctor or pharmacist again.

Your doctor will indicate the duration of treatment with Tosidrin.

The recommended dose of this medication, unless your doctor indicates otherwise, is as follows:

  • Adults and adolescents over 12 years: 20 to 30 drops, with a maximum of 4 doses per day.

Do not exceed the maximum dose of 30 mg of dihydrocodeine per day, which corresponds to 100 drops per day of this medication.

  • Children from 6 to 12 years: 1-2 drops per year of age, with a maximum of 4 doses per day.

Do not exceed the maximum dose of 15 mg of dihydrocodeine per day, which corresponds to 50 drops per day of this medication.

  • Children from 2 to 5 years: 1 drop per year of age, with a maximum of 4 doses per day.

Do not exceed the maximum dose of 7.5 mg of dihydrocodeine per day, which corresponds to 25 drops of this medication.

  • Children under 2 years: This medication is contraindicated and should not be taken.

Tosidrin is an oral solution. It can be taken directly or diluted in water.

If you take more Tosidrin than you should

In case you take more Tosidrin than you should, the symptoms that may occur are initial excitement, anxiety, insomnia, and later, in certain cases, drowsiness, lack of reflexes, headache, alteration of blood pressure, arrhythmia, dry mouth, hypersensitivity reactions, tachycardia, convulsions, gastrointestinal disorders, nausea, vomiting, and respiratory depression.

In case of overdose or accidental ingestion, you should immediately consult your doctor for symptomatic treatment or contact the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

In the treatment of overdose, an opioid antagonist should be administered.

If you forget to take Tosidrin

If you forget to take a dose, take it as soon as possible. Do not take a double dose to make up for forgotten doses.

If you stop taking Tosidrin

Administration should be gradually suspended after prolonged use, as physical dependence and tolerance may occur with repeated administration of this medication.

If you have any other questions about the use of this medication, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medications, this medication may have side effects, although not everyone experiences them.

During the use of Tosidrin, the following side effects have been observed, whose frequency could not be established with precision.

Gastrointestinal:

Nausea, vomiting, constipation.

Central Nervous System:

Dizziness, drowsiness, convulsions.

Skin and subcutaneous tissue:

Itching.

Immune system:

Skin rashes in allergic patients.

Respiratory, thoracic, and mediastinal:

Bronchospasm, respiratory depression at high doses

Psychiatric:

Confusion, euphoria, restlessness.

The conditions that favor the appearance of these side effects are, fundamentally, two: high doses and prolonged treatment.

Reporting side effects

If you experience any type of side effect, consult your doctor or pharmacist, even if it is a side effect not listed in this leaflet. You can also report them directly through the Spanish Medication Surveillance System for human use: www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Tosidrin

No special storage conditions are required.

Keep out of sight and reach of children.

Do not use this medication after the expiration date shown on the packaging, after CAD. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and medications you no longer need at the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and medications you no longer need. This will help protect the environment.

6. Package contents and additional information

Composition of Tosidrin

  • The active ingredient of Tosidrin is dihydrocodeine bitartrate. Each ml (equivalent to 33 drops) contains 10 mg of dihydrocodeine bitartrate.
  • The other components (excipients) are: Fluid extract of thyme, Fluid extract of sundew, Raspberry essence, Glycerol (E422), Ethanol, Sodium saccharin, and Purified water.

Appearance of the product and package contents

Tosidrin is a brown-colored solution with a raspberry odor, presented in amber glass bottles with a pilfer-proof dropper cap, containing 15 ml and 30 ml.

Marketing authorization holder and manufacturer

LABORATORIO DE APLICACIONES FARMACODINAMICAS, S.A. – FARDI logo

Grassot, 16 - 08025 Barcelona (Spain)

Date of the last revision of this leaflet: November 2015

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION

Discuss questions about TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Frequently Asked Questions

TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION is dihydrocodeine. This information helps identify medicines with the same composition but different brand names.

The average pharmacy price for TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION is around 7.31 EUR. Prices may vary depending on the manufacturer and dosage form.

TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION is manufactured by Laboratorio De Aplicaciones Farmacodinamicas S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

The prescription is issued by a doctor after assessing your health. In Spain, TOSIDRIN 10 mg/ml ORAL DROPS IN SOLUTION is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.

To request a review, you can use Oladoctor:

Other medicines with the same active substance (dihydrocodeine) include PARACODINA 2.4 mg/ml SYRUP, DOLODENS 100 mg/15 mg/10 mg FILM-COATED TABLETS, DUOXONA 10 mg/5 mg PROLONGED-RELEASE TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media