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Sulfuro 148-370 MBq/ml injectable suspensión

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Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension

Contents of the leaflet

  1. Introduction
  2. What Rhenium sulfide (186Re) CIS bio international is and what it is used for
  3. What you need to know before you start using Rhenium sulfide (186Re) CIS bio international
  4. How to use Rhenium sulfide (186Re) CIS bio international
  5. Possible side effects
  6. Storage of Rhenium sulfide (186Re) CIS bio international
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the Patient

Rhenium sulfide (186Re) CIS bio international 148-370 MBq/ml injectable suspension

Rhenium sulfide (186Re)

Read this package leaflet carefully before you start using this medicine.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your nuclear medicine doctor who is supervising the procedure.
  • If you experience any side effects, talk to your nuclear medicine doctor, even if they are not listed in this package leaflet. See section 4.

Contents of the package leaflet:

  1. What Rhenium sulfide (186Re) CIS bio international is and what it is used for
  2. What you need to know before you start using Rhenium sulfide (186Re) CIS bio international
  3. How to use Rhenium sulfide (186Re) CIS bio international
  4. Possible side effects
  5. Storage of Rhenium sulfide (186Re) CIS bio international
  6. Contents of the pack and further information

1. What Rhenium sulfide (186Re) CIS bio international is and what it is used for

This medicine is a radiopharmaceutical for therapeutic use only.

The active substance is rhenium sulfide (186Re).

Rhenium sulfide (186Re) CIS bio international is indicated for the treatment of rheumatoid disease affecting the shoulder, elbow, wrist, ankle, and hip joints.

Administration of Rhenium sulfide (186Re) CIS bio international involves receiving a small amount of radioactivity. Your doctor and nuclear medicine doctor have considered that the clinical benefit you will get from this procedure with the radiopharmaceutical outweighs the risk of radiation.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you start using Rhenium sulfide (186Re) CIS bio international

Do not use Rhenium sulfide (186Re) CIS bio international:

If you are allergic to rhenium sulfide (186Re) or any of the other components of this medicine (listed in section 6).

Warnings and precautions

Be careful with Rhenium sulfide (186Re) CIS bio international:

  • If you are pregnant or think you may be pregnant
  • If you are breast-feeding.
  • In children and adolescents during bone growth
  • If you have septic arthritis
  • If you have a rupture of the synovial capsule.
  • If you are going to be treated for the hip and have been given a long-acting corticosteroid.

Before administration of Rhenium sulfide (186Re) CIS bio international,

  • you should avoid pregnancy by using an effective contraceptive method for several months after treatment.

Children and adolescents

Consult your nuclear medicine doctor if you are under 18 years old.

Using Rhenium sulfide (186Re) CIS bio international with other medicines

Tell your nuclear medicine doctor if you are taking, have recently taken, or might take any other medicines, including those bought without a prescription.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your nuclear medicine doctor for advice before using this medicine.

You should tell your nuclear medicine doctor before administration of Rhenium sulfide (186Re) CIS bio international if there is any possibility that you are pregnant, if you have a delayed menstrual period, or if you are breast-feeding.

If you are a woman of childbearing age, you should use effective contraceptive measures before administration of this medicine and for several months after treatment.

In case of doubt, it is important that you consult your specialist nuclear medicine doctor who will supervise the procedure.

If you are pregnant or breast-feeding, you should not receive this medicine.

If you are breast-feeding, you should consider delaying the test with this medicine until you have stopped breast-feeding.

Driving and using machines

No effects on the ability to drive and use machines have been observed.

Rhenium sulfide (186Re) CIS bio international contains sodium

This medicine contains 12.7 mg of sodium (a major component of cooking/table salt) per ml. This is equivalent to 0.6% of the maximum recommended daily sodium intake for an adult. The amount of sodium administered may be higher than 23 mg in some cases. Therefore, this should be taken into account if you are on a low-sodium diet.

3. How to use Rhenium sulfide (186Re) CIS bio international

There are strict rules for the use, handling, and disposal of radiopharmaceuticals. Rhenium sulfide (186Re) CIS bio international will only be used in controlled areas. This product will only be handled and administered by trained and qualified personnel. These people will take special care in the safe use of this product and will inform you of their actions.

The nuclear medicine doctor who supervises the procedure will decide the amount of Rhenium sulfide (186Re) CIS bio international to be used in your case, which will be the minimum amount necessary to achieve the desired effect. The recommended amount for administration to an adult is 70 to 110 MBq (Megabecquerel, the unit used to express radioactivity) depending on the joint to be treated.

Administration of Rhenium sulfide (186Re) CIS bio international and performance of the procedure

Rhenium sulfide (186Re) CIS bio international is injected directly by your nuclear medicine doctor into the shoulder, elbow, wrist, ankle, or hip joints.

Several joints can be treated simultaneously or successively.

In case of relapse, a new injection into the joint may be considered after a 6-month break.

After administration of Rhenium sulfide (186Re) CIS bio international, you should:

  • Keep the joint immobilized for 3 days (splints or bed rest)
  • Use an effective contraceptive method for several months after treatment to avoid any pregnancy.
  • Avoid direct contact with small children and pregnant women.

Your nuclear medicine doctor will inform you if you need to take any special precautions after receiving this medicine. Consult your nuclear medicine doctor if you have any doubts.

If you have been given more Rhenium sulfide (186Re) CIS bio international than you should:

It is unlikely that you will be given an overdose because you will receive a single, precisely controlled dose of Rhenium sulfide (186Re) CIS bio international by the nuclear medicine doctor who supervises the procedure.

If you have any further questions on the use of Rhenium sulfide (186Re) CIS bio international, ask your nuclear medicine doctor who supervises the procedure.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported:

Common (may affect up to 1 in 10 patients)

  • Swelling due to fluid accumulation (edema)
  • Pigmentation disorder

Uncommon (may affect up to 1 in 100 patients)

  • Chromosomal abnormalities

Frequency not known (cannot be estimated from the available data)

  • Joint inflammation due to infection (septic arthritis)
  • Nausea
  • Vomiting
  • Bone death due to loss of blood flow (osteonecrosis)
  • Fluid loss in the joints (joint effusion)
  • Joint inflammation
  • Joint pain

The most frequently observed adverse reactions after synovectomy with rhenium are:

  • Brown discoloration of the wrist at the injection site and sometimes infiltration and stiffness of the extensor muscles.
  • Swelling due to fluid accumulation (edema) of the forearm after wrist synovectomy.
  • Transient local pain or joint inflammation (flare phenomenon) after joint puncture.
  • Nausea and vomiting.
  • Joint infection.
  • Bone death due to loss of blood flow.

Reporting of side effects

If you experience any side effects, talk to your nuclear medicine doctor, even if they are not listed in this package leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Rhenium sulfide (186Re) CIS bio international

You will not need to store this medicine. This medicine is stored under the responsibility of the specialist in suitable facilities. The storage of radiopharmaceuticals will be carried out in accordance with national regulations on radioactive materials.

6. Contents of the pack and further information

Composition of Rhenium sulfide (186Re) CIS bio international

  • The active substance is rhenium sulfide (186Re)
  • The other components are: ascorbic acid, gelatin, sodium hydroxide, hydrochloric acid, and water for injections.

Appearance of Rhenium sulfide (186Re) CIS bio international and contents of the pack

This medicine is presented as an injectable suspension in 15 ml glass vials closed with a rubber stopper and an aluminum cap. The vial is packaged with a lead shielded container

Pack size: One vial contains 37 to 3700 MBq of rhenium (186Re) at a concentration of 148 to 370 MBq/ml on the calibration date and time.

Marketing authorization holder and manufacturer:

CIS bio international

RN 306 - Saclay

B.P. 32

F-91192 Gif-sur-Yvette Cedex

FRANCE

You can request more information about this medicine from the local representative of the Marketing Authorization Holder:

Curium Pharma Spain S.A.

Avda. Dr. Severo Ochoa, 29

28100-Alcobendas

Phone: 91 4841989

This package leaflet was last revised in February 2020

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

This information is intended only for healthcare professionals:

The complete technical data sheet for Rhenium sulfide (186Re) CIS bio international is included as a separate document in the product packaging, in order to provide healthcare professionals with additional scientific and practical information on the administration and use of this radiopharmaceutical.

Please consult the technical data sheet.

Online doctors for Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension

Discuss questions about Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Frequently Asked Questions

Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension is rhenium (186Re) sulfide colloid. This information helps identify medicines with the same composition but different brand names.

Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension is manufactured by Cis Bio International. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

The prescription is issued by a doctor after assessing your health. In Spain, Rhenium Sulfide (186Re) Colloidal CIS BIO INTERNATIONAL 148-370 MBq/mL Injectable Suspension is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.

To request a review, you can use Oladoctor:

Other medicines with the same active substance (rhenium (186Re) sulfide colloid) include ERBIUM CITRATE (169Er) colloidal CIS BIO INTERNACIONAL 111 MBq/ML INJECTABLE SUSPENSION, Yttrium Citrate (90 Y) Colloidal CIS BIO INTERNATIONAL 37-370 MBq/ml Injectable Suspension, SODIUM IODIDE (I131) CURIUM PHARMA SPAIN 37-7400 MBq CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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