Bg pattern

VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

VasoKINOX 800 ppm mol/mol, medicinal compressed gas

Nitric oxide

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you experience any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is VasoKINOX 800 ppm mol/mol, medicinal compressed gas and what is it used for
  2. What you need to know before you start using VasoKINOX 800 ppm mol/mol, medicinal compressed gas
  3. How to use VasoKINOX 800 ppm mol/mol, medicinal compressed gas
  4. Possible side effects
  5. Storage of VasoKINOX 800 ppm mol/mol medicinal compressed gas
  6. Contents of the pack and further information

1. What is VasoKINOX and what is it used for

VasoKINOX is a gas mixture, composed of nitric oxide and nitrogen, used for

treatment of newborns with pulmonary insufficiencyassociated with increased blood pressure in the pulmonary circulation

treatment of acute pulmonary hypertension(increased blood pressure in the pulmonary circulation) that may occur during cardiac surgery in adults, children, and adolescents, from 0 to 17 years.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you start using VasoKINOX

Do not use VasoKINOX:

  • if you are hypersensitive to nitric oxide
  • in neonates with certain heart problems, such as abnormal circulation within the heart (right-to-left shunt, or left-to-right "malignant" arterial canal

Warnings and precautions

Talk to your doctor or nurse before you start using VasoKINOX.

  • Treatment with VasoKINOX should not be stopped abruptly.
  • Blood samples are taken before treatment and regularly during administration to monitor certain parameters.
  • There have been reports of fluid retention in the lungs with nitric oxide in patients with a disease caused by a blocked or narrow vein in the lungs. If you (as a patient) or your child (as a patient) experience shortness of breath or difficulty breathing, contact your doctor immediately.

Using VasoKINOX with other medicines

Tell your doctor if you are using, have recently used, or might use any other medicines.

  • VasoKINOX should be used with caution if the following medicines are taken at the same time:
  • "Nitric oxide donors" (such as medicines containing sodium nitroprusside and nitroglycerin). Their effect may be added to that of VasoKINOX.
  • Medicines that can increase the concentration of methemoglobin in the blood, such as those containing nitrate alkaloids and sulfonamides, prilocaine.
  • Prostacyclin and its analogs
    • It is up to the doctor to decide whether it is necessary to treat you with VasoKINOX and other medicines at the same time.

Pregnancy, breastfeeding, and fertility:

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Pregnancy:

The effect of administering VasoKINOX in pregnant women is unknown. As a precautionary measure, it is preferable to avoid using VasoKINOX during pregnancy.

Breastfeeding:

It is unknown whether nitric oxide/metabolites are excreted in human milk.

A decision must be made whether to discontinue breastfeeding or discontinue therapy with VasoKINOX, taking into account the benefits of breastfeeding for the child and the benefits of therapy for the woman.

Fertility:

No fertility studies have been conducted.

3. How to use VasoKINOX

Follow exactly the administration instructions of this medicine indicated by your doctor. In case of doubt, consult your doctor again.

  • VasoKINOX is a medicinal gas administered only in hospitals by healthcare professionals.
  • The doctor will determine the appropriate doseof VasoKINOX, as well as the duration of treatment, depending on your clinical condition and age.
  • VasoKINOX is administered by inhalation, through mechanical ventilationafter dilution in an air/oxygen mixture to patients in intensive care units with respiratory support and also in the operating room.
  • When in contact with oxygen, nitric oxide can be converted into nitrogen dioxide, which irritates the bronchi. For this reason, during its administration, the inhaled concentrations of nitric oxide and nitrogen dioxide are constantly measured.
  • Under certain clinical circumstances, it is possible to administer nitric oxide through ventilation with a maskfor a very short period (5 to 10 minutes).

If you use more VasoKINOX than you should:Your doctor will take the necessary measures

If you stop using VasoKINOX:

At the end of treatment in intensive care, the doctor will gradually reduce the dose of VasoKINOX administered (withdrawal phase), monitoring the change in your condition.

In fact, abrupt interruption of treatment after several hours of administration can cause a worsening of the clinical condition: this is what is called a "rebound effect".

If you have any other questions about the use of this medicine, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common side effects (affect more than 1 in 10 people) in association with VasoKINOX therapies include:

. Low platelet count in the blood

Common side effects (affect more than 1 in 100 people) in association with VasoKINOX therapies include:

. Low blood pressure, lack of air, or pulmonary collapse.

Uncommon side effects (affect between 1 in 100 and 1 in 1,000 people) are:

. Increased amount of methemoglobin (a form of hemoglobin that cannot carry oxygen) that reduces the amount of oxygen released in the tissues.

Side effects that may occur but whose frequency is unknown (frequency cannot be estimated from the available data) are:

. Bradycardia (slow heart rate) or too low oxygen levels in the blood (oxygen desaturation/hypoxemia) due to abrupt interruption of treatment

. Headache, dizziness, dry throat, or shortness of breath after accidental exposure to nitric oxide (e.g., equipment leak or balloon)

You should inform the staff directly if you experience a headache while you are near your child during treatment with VasoKINOX

Reporting of side effects:

If you experience any side effects, talk to your doctor or nurse, even if it is a possible side effect not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: http://www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of VasoKINOX

  • Keep this medicine out of the sight and reach of children.
  • Do not use this medicine after the expiry date stated on the label.
  • This medicine does not require special temperature conditions for storage.
  • The storage of VasoKINOX cylinders is carried out in the hospital.
  • The cylinder must be protected to avoid breakage and falls and must be kept away from any flammable or combustible material and humidity.
  • The cylinders must be kept in a vertical position and well secured and stored in a well-ventilated area.
  • When the gas cylinder is empty, do not dispose of it. The empty cylinders will be collected by the supplier.

6. Contents of the pack and further information

Composition of VasoKINOX

  • The active substance is nitric oxide; its dose is 800 ppm mol/mol
  • The other components are nitrogen

Appearance of the product and contents of the pack

A 2-liter cylinder filled to 200 bar provides 0.4 m3 of gas at a pressure of 1 bar at 15°C.

A 11-liter cylinder filled to 200 bar provides 2.1 m3 of gas at a pressure of 1 bar at 15°C

Marketing authorization holder and manufacturer

Marketing authorization holder

AIR LIQUIDE SantéINTERNATIONAL

75 Quai d’Orsay

75007 PARIS Cedex 07

FRANCE

Manufacturer

AIR LIQUIDE SantéFRANCE

“Les Petits Carreaux”

2, avenue du Lys

94380 BONNEUIL-SUR-MARNE

FRANCE

This medicine has been authorized in the EEA Member States with the following names:

  • Austria: VasoKINOX
  • Belgium: VasoKINOX
  • Denmark: VasoKINOX
  • Germany: VasoKINOX
  • Italy: VasoKINOX
  • Luxembourg: VasoKINOX
  • Norway: Vasokinox
  • Poland: VasoKINOX
  • Portugal: VasoKINOX- Spain: VasoKINOX
  • Switzerland: Vasokinox- Netherlands: VasoKINOX

Date of last revision of this leaflet: May 2025

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

------------------------------------------------------------------------------------------------------------------

This information is intended only for healthcare professionals:

To avoid any incidents, the following instructions must be strictly followed:

. Check that the equipment is in good condition before use

. Securely fasten the cylinders using chains or hooks in the basket to avoid accidental falls

. Never open a valve abruptly: open to the left, slowly and completely, then turn the valve a quarter turn

. Do not handle a cylinder whose valve is not protected by a tulip or protection system

. Use a specific ISO 5245 (2004) connector: No. 29 specific NO/N2 (100 ppm

. A pressure regulator that can withstand a pressure at least equal to 1.5 times the maximum operating pressure (200 bar) of the gas cylinder must be used

. For each new use, purge the pressure reducer/flow meter using a nitric oxide/nitrogen mixture

. Do not attempt to repair a faulty valve

. Do not tighten the pressure reducer/flow meter using a clamp, as this may damage the seal and the administration device

. Evacuate exhaled gases to the outside (avoiding areas where they can accumulate). Before use, it must be ensured that the room has an adequate ventilation system for gas evacuation in case of an accident or accidental leaks

. Since nitric oxide is colorless and odorless, the use of a detection system is recommended in all rooms where it will be used or stored

. European reference agencies responsible for occupational safety and health recommend the following exposure limits for medical personnel during 8 hours:

  • NO: 2 ppm (2.5 mg/m3)
  • NO2: 0.5 ppm (0.96 mg/m3)

To comply with the above recommendations, an analysis of nitric oxide and nitrogen dioxide in the atmosphere must be implemented.

. The installation of a nitric oxide piping system with a gas cylinder supply source, fixed network, and terminal units is prohibited.

Online doctors for VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL

Discuss questions about VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (25)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Camera Book a video appointment
€70
5.0 (808)
Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

Camera Book a video appointment
€55
0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
0.0 (6)
Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

Camera Book a video appointment
€55
5.0 (32)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60

Frequently Asked Questions

Is a prescription required for VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL?
VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL?
The active ingredient in VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL is nitric oxide. This information helps identify medicines with the same composition but different brand names.
Who manufactures VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL?
VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL is manufactured by Air Liquide Sante International. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to VASOKINOX 800 PPM GAS COMPRESSED MEDICINAL?
Other medicines with the same active substance (nitric oxide) include INOMAX 400 PPM MOL, COMPRESSED MEDICAL GAS, INOMAX 400 PPM MOL, COMPRESSED MEDICAL GAS, INOMAX 800 PPM MOL/MOL, COMPRESSED MEDICAL GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media