Background pattern
OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

Ask a doctor about a prescription for OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

Introduction

Package Leaflet: Information for the User

Osmille D 600 mg/1,000 IU Orodispersible Tablets

Calcium carbonate/colecalciferol

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What Osmille D is and what it is used for
  2. What you need to know before you take Osmille D
  3. How to take Osmille D
  4. Possible side effects
  5. Storage of Osmille D
  6. Contents of the pack and further information

1. What Osmille D is and what it is used for

Osmille D is used to prevent and treat calcium or vitamin D3 deficiency in elderly people and as additional treatment in osteoporosis in patients at risk of vitamin D or calcium deficiency, when a dietary supplement of 600 mg/day of calcium and 1,000 IU/day of vitamin D3 is appropriate.

Osmille D contains calcium and vitamin D3, both important components in bone formation. Vitamin D3 regulates the absorption and metabolism of calcium as well as the incorporation of calcium into bone tissue.

Ask your doctor or pharmacist if you have any questions and always follow their instructions.

You should consult a doctor if it gets worse or does not improve after several days.

2. What you need to know before you take Osmille D

Do not take Osmille D

  • If you are allergic to calcium, vitamin D, or any of the other ingredients of this medicine (listed in section 6).
  • If you have hypercalcemia (high levels of calcium in the blood) or hypercalciuria (high levels of calcium in the urine).
  • If you have hypervitaminosis D (high levels of vitamin D in the blood).
  • If you have kidney stones.
  • If you have kidney failure.
  • If you are allergic to soy or peanuts.

Warnings and precautions

Consult your doctor or pharmacist before taking Osmille D

  • if you have sarcoidosis (a special type of connective tissue disease that affects the lungs, skin, and joints).
  • if you are taking other medicines that contain vitamin D or calcium.
  • if your kidneys do not work well or you have a tendency to form kidney stones.
  • if you are immobilized due to osteoporosis.

Other medicines and Osmille D

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

The effect of treatment may be affected if this medicine is taken at the same time as other medicines for:

  • high blood pressure (thiazide diuretics)
  • heart problems (cardiac glycosides such as digoxin)
  • high cholesterol (cholestyramine)
  • constipation (laxatives such as liquid paraffin)
  • epilepsy (phenytoins or barbiturates)
  • inflammatory diseases/immunosuppression (corticosteroids)
  • obesity (orlistat)

Please make sure your doctor knows if you are taking any of the medicines listed above. Your dose may need to be adjusted.

If you take at the same time a medicine for

  • osteoporosis (bisphosphonates)

you should take it at least one hour before taking Osmille D.

If you take at the same time medicines for

  • infections (quinolones)

you should take them two hours before or six hours after taking Osmille D.

If you take at the same time medicines for

  • infections (tetracyclines)

you should take them two hours before or six hours after taking Osmille D.

If you take at the same time medicines for

  • dental caries (sodium fluoride)
  • anemia (iron)

you should take these medicines at least three hours before taking Osmille D.

If you take at the same time medicines for

  • hypothyroidism (levothyroxine)

you should take Osmille D at least four hours apart.

Taking Osmille D with food, drinks, and alcohol

The absorption of calcium may be inhibited by foods containing oxalic acid (present in spinach and rhubarb) or phytic acid (present in whole grains). You should wait at least two hours before taking Osmille D if you have taken foods with high oxalic acid or phytic acid content.

Pregnancy, breast-feeding, and fertility

During pregnancy, the daily intake should not exceed 1,500 mg of calcium and 600 IU of vitamin D. Therefore, it is not recommended to take Osmille D during pregnancy.

Osmille D can be taken during breastfeeding. Calcium and vitamin D3 pass into breast milk. This should be taken into account when vitamin D is additionally administered to the infant.

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.

Driving and using machines

No effects on the ability to drive and use machines have been observed.

Osmille Dcontains aspartame

This medicine contains 8.67 mg of aspartame in each tablet. Aspartame is a source of phenylalanine that may be harmful in cases of phenylketonuria (PKU), a rare genetic disorder in which phenylalanine accumulates because the body is unable to eliminate it properly.

Osmille D contains lactose and sucrose

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine. It may harm your teeth.

3. How to take Osmille D

Follow exactly the administration instructions of this medicine given by your doctor or pharmacist. If you are in doubt, consult your doctor or pharmacist again.

The dose is established by your doctor individually.

The recommended dose is 1 tablet per day.

The tablets should be dissolved in the mouth. They should not be swallowed whole.

The tablets should be taken preferably after meals.

The amount of calcium in Osmille D is less than the daily intake usually recommended. Osmille D is therefore recommended in patients who need an additional intake of vitamin D, but with a daily intake of 500-1,000 mg of calcium per day. The dose of calcium recommended for you should be established by your doctor.

Use in children and adolescents

Osmille D is not indicated in children and adolescents.

If you take moreOsmille Dthan you should

If you have taken more Osmille D than you should, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount taken.

The symptoms of an overdose of Osmille D may include loss of appetite, thirst, abnormal emission of large amounts of urine, nausea, vomiting, and constipation.

If you forget to take Osmille D

Take it as soon as you remember. Then take the next dose as usual. However, if it is already time for your next dose, skip the missed dose and continue as usual. Do not take a double dose to make up for missed doses.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

You should stop taking Osmille D and inform your doctor immediately if you experience symptoms of severe allergic reactions such as:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty swallowing
  • Hives and difficulty breathing.

Uncommon side effects (may affect up to 1 in 100 people):hypercalcemia (elevated calcium levels in serum) and/or hypercalciuria (elevated calcium levels in urine).

Rare side effects (may affect up to 1 in 1,000 people):constipation, flatulence, nausea, abdominal pain, diarrhea, pruritus, rash, and urticaria.

Side effects with unknown frequency (frequency cannot be estimated from the available data):severe allergic reactions.

Other special populations

Patients with renal insufficiency may have a potential risk of hyperphosphatemia, nephrolithiasis, and nephrocalcinosis.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Osmille D

Keep this medicine out of the sight and reach of children.

Keep the container perfectly closed.

Do not use this medicine after the expiry date which is stated on the container after EXP. The expiry date is the last day of the month indicated.

Store in the original container to protect from light. Keep the container perfectly closed to protect from moisture.

The shelf life after first opening is 60 days.

Do not use this medicine if you notice any visible signs of deterioration.

Medicines should not be disposed of via wastewater or household waste. Place the container and any unused medicine in the SIGRE collection point at your pharmacy. If you have any further questions on the disposal of unused medicines, ask your pharmacist. This will help protect the environment.

6. Contents of the pack and further information

Composition of Osmille D

  • The active ingredients are calcium carbonate and colecalciferol (vitamin D3). Each tablet contains 1,500 mg of calcium carbonate equivalent to 600 mg of calcium and 1,000 IU of colecalciferol equivalent to 0.025 mg.
  • The other ingredients are: maltodextrin, aspartame (E951), low-substituted hydroxypropylcellulose (E463), lactose monohydrate, anhydrous citric acid (E330), orange flavor, stearic acid, all-rac-α-tocopherol (E307), partially hydrogenated soybean oil, gelatin, sucrose, corn starch, silicon dioxide.

Appearance of the product and contents of the pack

Osmille D is presented in the form of white or almost white, circular, beveled orodispersible tablets.

Bottles of 30 or 60 tablets.

Not all pack sizes may be marketed.

Marketing authorization holder

ITALFARMACO, S.A.

C/ San Rafael, 3

28108 Alcobendas, Madrid

Spain

Tel.: 91 657 23 23

Manufacturer

ITALFARMACO, S.p.A.

Viale Fulvio Testi 330

20126 Milan

Italy

You can request more information about this medicine from the local representative of the marketing authorization holder

Laboratorios EFFIK S.A.

C/ San Rafael, 3

28108 Alcobendas, Madrid

Spain

Tel: 91 358 52 73

This medicine is authorized in the Member States of the European Economic Area under the following names

Spain Osmille D 600 mg/1,000 IU orodispersible tablets

Italy Natemille 600 mg/1,000 IU orodispersible tablets

Date of the last revision of this leaflet:January 2022

Updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

About the medicine

How much does OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS cost in Spain ( 2025)?

The average price of OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS in December, 2025 is around 9.01 EUR. Prices may vary depending on the region, pharmacy, and whether a prescription is required. Always check with a local pharmacy or online source for the most accurate information.

Alternatives to OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS in Poland

Dosage form: Tablets, 600 mg + 800 IU
Importer: Beres Pharmaceuticals Ltd.
Prescription required
Dosage form: Tablets, 500 mg + 2000 IU
Dosage form: Tablets, 1000 mg + 880 IU
Prescription not required
Dosage form: Tablets, 1000 mg + 880 IU
Dosage form: Tablets, 600 mg + 400 IU
Prescription not required
Dosage form: Tablets, 500 mg + 10 mcg

Alternative to OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS in Ukraine

Dosage form: tablets, 10 tablets in a blister
Manufacturer: ZAT "Beres Farma
Prescription not required
Dosage form: tablets, 10 tablets in a blister
Prescription not required
Dosage form: tablets, chewable tablets 30
Prescription not required
Dosage form: tablets, chewable tablets 30
Prescription not required
Dosage form: tablets, 30 tablets in a bottle
Dosage form: tablets, 30 or 100 tablets in a bottle
Prescription not required

Online doctors for OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for OSMILLE D 600 MG/1000 IU ORALLY DISINTEGRATING TABLETS – subject to medical assessment and local rules.

5.0(21)
Doctor

Ekaterina Agapova

Neurology8 years of experience

Dr. Ekaterina Agapova is a neurologist specialising in the diagnosis and treatment of neurological conditions and chronic pain. She provides online consultations for adults, combining evidence-based medicine with a personalised approach.

She offers expert care for:

  • Headaches and migraines, including tension-type and cluster headaches.
  • Neck and back pain, both acute and chronic.
  • Chronic pain syndromes – fibromyalgia, neuropathic pain, post-traumatic pain.
  • Mononeuropathies – carpal tunnel syndrome, trigeminal neuralgia, facial nerve palsy.
  • Polyneuropathies – diabetic, toxic, and other types.
  • Multiple sclerosis – diagnosis, monitoring, long-term support.
  • Dizziness and coordination disorders.
  • Sleep disturbances – insomnia, daytime sleepiness, fragmented sleep.
  • Anxiety, depression, and stress-related conditions.

Dr. Agapova helps patients manage complex neurological symptoms like pain, numbness, weakness, poor sleep, and emotional distress. Her consultations focus on accurate diagnosis, clear explanation of findings, and tailored treatment plans.

If you’re struggling with chronic pain, migraines, nerve disorders, or sleep problems, Dr. Agapova offers professional guidance to restore your well-being.

CameraBook a video appointment
€49
December 2606:00
December 2606:45
December 2607:30
December 2609:30
December 2610:15
More times
0.0(0)
Doctor

Katia Benko

Pediatrics9 years of experience

Dr Katia Benko is a paediatrician with over 9 years of clinical experience and international training. She completed her medical education and residency in Argentina and is fully licensed to practise in Spain. Her work spans newborns, children and adolescents, with a focus on whole-person care that integrates physical, emotional and developmental health.

Areas of expertise:

  • online consultations for newborns, children and teens
  • evaluation and treatment of acute symptoms: fever, cough, infections, bronchiolitis, earache, etc.
  • long-term care for chronic paediatric conditions
  • preventive care at every stage of growth and development
  • child wellness visits and routine health check-ups
  • vaccination guidance according to standard and special schedules
  • assessment of neurodevelopment in infants and toddlers
  • feeding concerns: picky eating, food refusal, healthy habits, eating disorders
  • parental support in everyday health, emotional wellbeing and prevention
  • guidance for teenagers on healthy habits, self-care and risk prevention
Dr Benko sees paediatrics as a space for partnership with families – not only to treat illness, but to guide each child’s health journey with clarity, empathy and trust. Her goal is for every family to feel supported in making confident, informed decisions for their child’s wellbeing.
CameraBook a video appointment
€59
December 2615:00
December 2615:30
December 2616:00
December 2616:30
December 2711:30
More times
5.0(12)
Doctor

Dmytro Horobets

Family medicine6 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

CameraBook a video appointment
€60
December 2709:00
December 2709:30
January 309:00
January 309:30
January 1009:00
More times
0.0(2)
Doctor

Marianna Neshta

Endocrinology24 years of experience

Marianna Neshta is a medical doctor specialising in endocrinology and ultrasound diagnostics. She provides online consultations for adults, focusing on the diagnosis, treatment, and long-term management of endocrine disorders. Her approach includes personalised care plans, analysis of lab results and ultrasound scans, and evidence-based treatment.

Key areas of expertise:

  • Type 1 and Type 2 diabetes – diagnosis, therapy adjustment, CGM interpretation, and prevention of chronic complications
  • Obesity – treatment using both medication and lifestyle strategies, including modern GLP-1 medications and tailored follow-up plans
  • Thyroid disorders – ultrasound assessment, treatment planning, and management during pregnancy
  • Male hypogonadism – age-related or hormonal, including diagnostics and therapy
  • Metabolic syndrome, prediabetes, lipid disorders – risk assessment, lifestyle recommendations, and medical treatment
  • Calcium metabolism disorders – diagnosis and management of osteoporosis, hyperparathyroidism, and hypoparathyroidism
Dr Neshta applies current clinical guidelines and diagnostic tools, offering medical support adapted to each patient’s individual needs — all in an accessible online format.
CameraBook a video appointment
€45
December 2717:00
December 2717:45
January 317:00
January 317:45
January 1017:00
More times
0.0(1)
Doctor

Khrystyna Habrykevych

Gastroenterology6 years of experience

Dr Khrystyna Habrykevych is a gastroenterologist providing online consultations for adults with digestive and abdominal health concerns. She helps patients understand the causes of their symptoms, interpret test results, and choose appropriate next steps – whether it’s further investigation, treatment, or lifestyle adjustments.

Common reasons for consultation include:

  • abdominal pain, cramps, discomfort, painful bowel movements
  • heartburn, acid reflux, burping, bitter taste in the mouth
  • bloating, excessive gas, nausea or vomiting
  • diarrhoea, constipation, difficulty passing stool
  • unexplained changes in weight or appetite
  • concern about gut health or long-term digestive issues
  • changes in lab results, questions about test interpretation
  • digestive system cancer screening and prevention
  • general digestive check-ups and health assessments
Dr Habrykevych follows evidence-based medical standards and adapts each consultation to the patient’s individual situation. The online format allows for timely medical support without the need for an in-person visit.
CameraBook a video appointment
€60
December 2806:00
January 406:00
January 1106:00
January 1806:00
More times
0.0(1)
Doctor

Sergei Nalkin

Neurology11 years of experience

Dr. Sergei Nalkin, PhD, is a neurologist, specialising in sports medicine and rehabilitation. He provides expert care for patients with neurological, musculoskeletal, and post-traumatic conditions, focusing on functional recovery and long-term symptom relief.

Dr. Nalkin offers consultations and treatment for:

  • Neurological disorders including migraines, tension headaches, and peripheral neuropathies.
  • Rehabilitation after stroke, brain injury, and spinal cord trauma.
  • Chronic pain syndromes and musculoskeletal dysfunctions.
  • Sports-related injuries: prevention, treatment, and recovery planning.
  • Coordination and movement disorders affecting mobility and balance.
  • Custom rehabilitation programmes for neurological and orthopedic conditions.

With a personalised, evidence-based approach, Dr. Nalkin helps patients restore physical function, reduce pain, and improve quality of life through targeted therapy and long-term support.

CameraBook a video appointment
€55
December 2813:00
December 2813:40
December 2814:20
December 2815:00
January 413:00
More times
0.0(0)
Doctor

Liudmyla Boichuk

Family medicine10 years of experience

Dr Liudmyla Boichuk is a family medicine doctor providing diagnosis and treatment for a wide range of acute and chronic conditions in adults and children. She works with respiratory, cardiovascular and digestive system disorders and has extensive experience caring for patients with multiple coexisting conditions, where coordinated, whole-person management is essential.

She treats adults with respiratory illnesses such as pneumonia, COPD and bronchial asthma, as well as cardiovascular conditions including hypertension and ischaemic heart disease. Her practice also covers gastrointestinal complaints and chronic comorbidities that require careful, structured medical supervision.

Dr Boichuk provides care for children from birth, including acute respiratory viral infections, infectious diseases, pneumonia, bronchitis, bronchial obstruction syndromes and allergic reactions. She offers clear, evidence-based guidance to parents and ensures safe follow-up throughout the child’s recovery.

Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

CameraBook a video appointment
€55
December 2813:30
January 413:30
January 1113:30
January 1813:30
More times
0.0(3)
Doctor

Alexandra Alexandrova

General medicine8 years of experience

Dr Alexandra Alexandrova is a licensed general medicine doctor in Spain, specialising in trichology, nutrition, and aesthetic medicine. She offers online consultations for adults, combining a therapeutic approach with personalised care for hair, scalp, and overall health.

Areas of expertise:

  • Hair loss in women and men, postpartum hair loss, androgenetic and telogen effluvium.
  • Scalp conditions: seborrheic dermatitis, psoriasis, scalp irritation, dandruff.
  • Chronic conditions: hypertension, diabetes, metabolic disorders.
  • Online trichology consultation: customised treatment plans, nutritional support, hair growth stimulation.
  • Hair loss prevention: hormonal imbalance, stress factors, haircare strategies.
  • Routine health check-ups, prevention of cardiovascular and metabolic diseases.
  • Personalised nutritional advice to improve hair strength, skin health, and hormonal balance.
  • Aesthetic medicine: non-invasive strategies to enhance skin quality, tone, and metabolic wellness.

Dr Alexandrova follows an evidence-based and holistic approach: online consultations with a therapist and trichologist on Oladoctor provide professional support for hair, scalp, and overall health — all from the comfort of your home.

CameraBook a video appointment
€59
January 809:00
January 809:30
January 810:00
January 810:30
January 811:00
More times
5.0(128)
Doctor

Taisiia Proida

Psychiatry6 years of experience

Dr. Taisiia Proida is a psychiatrist and cognitive behavioural therapist (CBT), and a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care.

She specialises in consultations and ongoing support for a wide range of mental health concerns, including:

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders.

She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

CameraBook a video appointment
€120
January 1913:00
January 1917:00
More times

Get updates and exclusive offers

Be the first to know about new services, marketplace updates, and subscriber-only promos.

Follow us on social media
FacebookInstagram
Logo
Oladoctor
Find a doctor
Doctors by specialty
Services
Choose language
© 2025 Oladoctor. All rights reserved.
VisaMastercardStripe