Bg pattern

MAVIRET 100 mg/40 mg FILM-COATED TABLETS

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use MAVIRET 100 mg/40 mg FILM-COATED TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Maviret 100mg/40mg film-coated tablets

glecaprevir/pibrentasvir

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Maviret and what is it used for
  2. What you need to know before you take Maviret
  3. How to take Maviret
  4. Possible side effects
  5. Storage of Maviret
  6. Contents of the pack and other information

1. What is Maviret and what is it used for

Maviret is an antiviral medicine used to treat adults and children (from 3 years of age) with long-term (chronic) hepatitis C infection. This is an infectious disease that affects the liver and is caused by the hepatitis C virus. Maviret contains the active substances glecaprevir and pibrentasvir.

Maviret works by preventing the hepatitis C virus from multiplying and infecting new cells. This eliminates the infection from the body.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Maviret

Do not take Maviret:

  • if you are allergic to glecaprevir, pibrentasvir or any of the other ingredients of this medicine (listed in section 6).
  • if you have severe liver problems, other than hepatitis C.
  • if you are taking the following medicines:
    • atazanavir (for HIV infection)
    • atorvastatin or simvastatin (to lower blood cholesterol)
    • carbamazepine, phenobarbital, phenytoin, primidone (usually used for epilepsy)
    • dabigatran etexilate (to prevent blood clots)
    • medicines containing ethinylestradiol (such as contraceptive medicines, including vaginal rings, transdermal patches and tablets)
    • rifampicin (for infections)
    • St. John's Wort (Hypericum perforatum), (herbal medicine used for mild depression).

Do not take Maviret if you are in any of the above situations. If in doubt, consult your doctor or pharmacist before taking Maviret.

Warnings and precautions

Tell your doctor if you are in any of the following situations, as you may need closer monitoring:

  • you have liver problems other than hepatitis C
  • you have had or currently have a hepatitis B virus infection
  • you have diabetes. After starting Maviret, you may need close monitoring of your blood glucose levels and/or adjustment of your diabetic medication. After starting treatment with medicines like Maviret, some diabetic patients have experienced low blood sugar levels (hypoglycaemia).

Blood tests

Your doctor will perform blood tests before, during and after treatment with Maviret. This will help determine:

  • if you should take Maviret and for how long
  • if the treatment has worked and you no longer have the hepatitis C virus.

Children

This medicine must not be given to children under 3 years of age or weighing less than 12 kg. The use of Maviret in children under 3 years of age or weighing less than 12 kg has not been studied yet.

Other medicines and Maviret

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Tell your doctor or pharmacistbefore taking Maviret if you are taking any of the medicines listed in the following table. Your doctor may need to change the dose of these medicines.

Medicines that you should tell your doctor about before taking Maviret

Medicine

Purpose of the medicine

ciclosporin, tacrolimus

to reduce the activity of the immune system

darunavir, efavirenz, lopinavir, ritonavir

for HIV infection

digoxin

for heart problems

fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin

to lower blood cholesterol

warfarin and other similar medicines*

to prevent blood clots

  • Your doctor may increase the frequency of your blood tests to check the proper functioning of your blood clotting process.

If you are in any of the above situations (or are unsure), consult your doctor or pharmacist before taking Maviret.

Pregnancy and contraception

The effects of Maviret during pregnancy are not known. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine, as it is not recommended to take Maviret during pregnancy. Contraceptive medicines containing ethinylestradiol must not be used in combination with Maviret.

Breast-feeding

Ask your doctor or pharmacist for advice before taking Maviret if you are breast-feeding. It is not known if the active substances in Maviret pass into breast milk.

Driving and using machines

Maviret is unlikely to affect your ability to drive or use tools or machines.

Maviret contains lactose

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

3. How to take Maviret

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. Your doctor will tell you how long you need to take Maviret.

Maviret tablets are for adults, children from 12 years of age, or children weighing 45 kg or more. Maviret granules are for children from 3 years of age to less than 12 years and weighing 12 kg to less than 45 kg.

How much to take

The recommended dose for adults, children from 12 years of age, or children weighing at least 45 kg is three Maviret 100 mg/40 mg tablets taken together, once a day. The daily dose is the three tablets from one blister.

How to take the medicine

  • Take the tablets with food.
  • Swallow the tablets whole.
  • Do not chew, crush or break them, as this may affect the amount of Maviret in your blood.

If you vomit after taking Maviret, the amount of this medicine in your blood may be affected. In this case, the effectiveness of Maviret may be lower.

  • If you vomit when it has been less than 3hourssince you took Maviret, take another dose.
  • If you vomit when it has been more than 3hourssince you took Maviret, do not take another dose until your next scheduled dose.

If you take more Maviret than you should

If you accidentally take a higher dose than recommended, consult your doctor or go to the nearest hospital immediately. Take the medicine pack with you to show the doctor what you have taken.

If you forget to take Maviret

It is important not to miss any doses of this medicine.

If you forget to take a dose, calculate how long it has been since you should have taken Maviret:

  • If it has been less than 18hourssince you should have taken your Maviret dose, take it as soon as possible. Then take your next dose at the usual time.
  • If it has been 18hours or moresince you should have taken your Maviret dose, wait and take your next dose at the usual time. Do not take a double dose to make up for a forgotten dose.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor or pharmacist if you notice any of the following side effects:

Very common:may affect more than 1 in 10 people

  • feeling very tired (fatigue)
  • headache

Common:may affect up to 1 in 10 people

  • feeling sick (nausea)
  • diarrhoea
  • feeling weak or lacking energy (asthenia)
  • increase in a laboratory test of liver function (bilirubin)

Uncommon:may affect up to 1 in 100 people

  • swelling of the face, lips, tongue, throat, abdomen, arms or legs

Frequency not known:cannot be estimated from the available data

  • itching

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in the Yellow Card Scheme: www.mhra.gov.uk/yellowcard. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Maviret

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after “EXP” and on the blister after “EXP”. The expiry date refers to the last day of the month shown.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information

What Maviret contains

  • The active substances are glecaprevir and pibrentasvir. Each tablet contains 100 mg of glecaprevir and 40 mg of pibrentasvir.
  • The other ingredients are:
  • Tablet core: copovidone (type K 28), vitamin E succinate, colloidal anhydrous silica, propylene glycol monocaprylate (type II), sodium croscarmellose, sodium stearyl fumarate.
  • Tablet coating: hypromellose (E464), lactose monohydrate, titanium dioxide, macrogol 3350, red iron oxide (E172).

Maviret contains lactose and sodium. See section 2.

Appearance and packaging

Maviret tablets are pink, oval, biconvex, film-coated tablets, 18.8 mm x 10.0 mm in size, marked with “NXT” on one side.

Maviret tablets are packaged in blisters containing 3 tablets each. Maviret is available in packs of 84 tablets, with 4 boxes, each containing 21 film-coated tablets.

Marketing Authorisation Holder

AbbVie Deutschland GmbH & Co. KG

Knollstrasse

67061 Ludwigshafen

Germany

Manufacturer

AbbVie Deutschland GmbH & Co. KG

Knollstrasse

67061 Ludwigshafen

Germany

or

AbbVie Logistics B.V

Zuiderzeelaan 53

8017 JV Zwolle

Netherlands

For further information about this medicine, contact the local representative of the Marketing Authorisation Holder:

België/Belgique/Belgien

AbbVie SA

Tél/Tel: +32 10 477811

Lietuva

AbbVie UAB

Tel: +370 5 205 3023

????????

???? ????

???.: +359 2 90 30 430

Luxembourg/Luxemburg

AbbVie SA

Belgique/Belgien

Tél/Tel: +32 10 477811

Ceská republika

AbbVie s.r.o.

Tel: +420 233 098 111

Magyarország

AbbVie Kft.

Tel.: +36 1 455 8600

Danmark

AbbVie A/S

Tlf: +45 72 30‑20‑28

Malta

V.J.Salomone Pharma Limited

Tel: +356 22983201

Deutschland

AbbVie Deutschland GmbH & Co. KG

Tel: 00800 222843 33 (gebührenfrei)

Tel: +49 (0) 611 / 1720‑0

Nederland

AbbVie B.V.

Tel: +31 (0)88 322 2843

Eesti

AbbVie OÜ

Tel: +372 623 1011

Norge

AbbVie AS

Tlf: +47 67 81 80 00

Ελλ?δα

AbbVie ΦΑΡΜΑΚΕΥΤΙΚΗ Α.Ε.

Τηλ: +30 214 4165 555

Österreich

AbbVie GmbH

Tel: +43 1 20589‑0

España

AbbVie Spain, S.L.U.

Tel: +34 91 384 09 10

Polska

AbbVie Polska Sp. z o.o.

Tel.: +48 22 372 78 00

France

AbbVie

Tél: +33 (0)1 45 60 13 00

Portugal

AbbVie, Lda.

Tel: +351 (0)21 1908400

Hrvatska

AbbVie d.o.o.

Tel: +385 (0)1 5625 501

România

AbbVie S.R.L.

Tel: +40 21 529 30 35

Ireland

AbbVie Limited

Tel: +353 (0)1 4287900

Slovenija

AbbVie Biofarmacevtska družba d.o.o.

Tel: +386 (1)32 08 060

Ísland

Vistor hf.

Sími: +354 535 7000

Slovenská republika

AbbVie s.r.o.

Tel: +421 2 5050 0777

Italia

AbbVie S.r.l.

Tel: +39 06 928921

Suomi/Finland

AbbVie Oy

Puh/Tel: +358 (0)10 2411 200

Κ?προς

Lifepharma (Z.A.M.) Ltd

Τηλ: +357 22 34 74 40

Sverige

AbbVie AB

Tel: +46 (0)8 684 44 600

Latvija

AbbVie SIA

Tel: +371 67605000

United Kingdom (Northern Ireland)

AbbVie Deutschland GmbH & Co. KG

Tel: +44 (0)1628 561090

Date of last revision of this leaflet: 05/2022

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency web site: http://www.ema.europa.eu.

To request a copy of this leaflet in large print, contact the local representative of the Marketing Authorisation Holder.

Online doctors for MAVIRET 100 mg/40 mg FILM-COATED TABLETS

Discuss questions about MAVIRET 100 mg/40 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (79)
Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Camera Book a video appointment
€59
5.0 (19)
Doctor

Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate

Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

Camera Book a video appointment
€50
0.0 (0)
Doctor

Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

Camera Book a video appointment
€60
5.0 (76)
Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

Camera Book a video appointment
€69
0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
0.0 (11)
Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for MAVIRET 100 mg/40 mg FILM-COATED TABLETS?
MAVIRET 100 mg/40 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MAVIRET 100 mg/40 mg FILM-COATED TABLETS?
The active ingredient in MAVIRET 100 mg/40 mg FILM-COATED TABLETS is glecaprevir and pibrentasvir. This information helps identify medicines with the same composition but different brand names.
Who manufactures MAVIRET 100 mg/40 mg FILM-COATED TABLETS?
MAVIRET 100 mg/40 mg FILM-COATED TABLETS is manufactured by Abbvie Deutschland Gmbh & Co. Kg. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MAVIRET 100 mg/40 mg FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MAVIRET 100 mg/40 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MAVIRET 100 mg/40 mg FILM-COATED TABLETS?
Other medicines with the same active substance (glecaprevir and pibrentasvir) include MAVIRET 50 mg/20 mg GRANULES, COATED, IN SACHET, EPCLUSA 150 mg/37.5 mg COATED GRANULES IN SACHET, EPCLUSA 200 mg/50 mg COATED GRANULES IN SACHET. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media