This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use LAMIVUDINE NORMON 300 mg FILM-COATED TABLETS

Introduction

Package Leaflet: Information for the User

Lamivudine Normon 300 mg Film-Coated Tablets EFG

Lamivudine

Read all of this leaflet carefully before you start taking this medicine.

Keep this leaflet, you may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you, do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Contents of the Package Leaflet

What is Lamivudine Normon 300 mg Tablets and what is it used for
What you need to know before you take Lamivudine Normon 300 mg Tablets
How to take Lamivudine Normon 300 mg Tablets
Possible side effects
Storage of Lamivudine Normon 300 mg Tablets
Package Contents and Further Information

1. What is Lamivudine Normon 300 mg Tablets and what is it used for

Lamivudine belongs to a group of antiviral medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs), which are used to treat HIV infection.

Lamivudine Normon 300 mg is used in combination antiretroviral therapy for the treatment of HIV infection in adults and children. Lamivudine Normon reduces the amount of HIV in your body, keeping it at low levels. It also increases the number of CD4 cells in your blood. CD4 cells are a type of white blood cell that plays an important role in maintaining a healthy immune system to help fight infection. The response to treatment with Lamivudine Normon 300 mg varies between patients. Your doctor will monitor the effectiveness of your treatment.

2. What you need to know before you take Lamivudine Normon 300 mg Tablets

Do not take Lamivudine Normon 300 mg Tablets:

If you are allergic to lamivudine or any of the other ingredients of Lamivudine Normon Tablets.

If you are not sure, please ask your doctor.

Take special care with Lamivudine Normon 300 mg Tablets:

Talk to your doctor about taking Lamivudine Normon if you have kidney disease. You may need to take a lower dose of Lamivudine Normon.

The class of medicines to which lamivudine belongs (NRTIs) can cause a condition called lactic acidosis (build-up of lactic acid in the body), as well as an increase in the size of the liver. Lactic acidosis, if it occurs, usually develops after a few months of treatment. Rapid breathing, deep and fast, drowsiness and non-specific symptoms such as nausea, vomiting and stomach pain may indicate the development of lactic acidosis. This rare but serious side effect has been fatal in some cases. Lactic acidosis occurs more often in women, particularly if they are overweight. If you have liver disease, you may also have a higher risk of developing this condition. While you are being treated with Lamivudine Normon, your doctor will regularly check for any signs that you may be developing lactic acidosis.

Redistribution, accumulation or loss of body fat may occur in patients receiving combination antiretroviral therapy. Contact your doctor if you notice changes in body fat.

In some patients with advanced HIV infection (AIDS) and a history of opportunistic infections, signs and symptoms of inflammation from previous infections may occur soon after anti-HIV treatment is started. It is believed that these symptoms are due to an improvement in the body's immune response, enabling it to fight infections that have been present without causing symptoms. If you notice any symptoms of infection, please inform your doctor immediately.

Please talk to your doctor if you have a history of liver disease. Patients with chronic hepatitis B or C and treated with antiretroviral agents have a higher risk of severe and potentially fatal liver reactions and may require blood tests to monitor liver function.

If you have chronic hepatitis B, you should not stop taking Lamivudine Normon without your doctor's advice, as you may experience a recurrence of hepatitis. This recurrence can be more severe if you have severe liver disease.

You will need to take Lamivudine Normon every day. This medicine helps control your condition, but it does not cure HIV infection. You may still develop other infections and illnesses associated with HIV. You must keep regular contact with your doctor. Do not stop taking the medicine without talking to your doctor first.

Treatment with Lamivudine Normon has not been shown to reduce the risk of transmitting HIV to others through sexual contact or blood transfusion. You must continue to take precautions to avoid this.

Bone problems: some patients taking combination antiretroviral therapy may develop a bone disease called osteonecrosis (death of bone tissue due to loss of blood supply to the bone). Among the many risk factors for developing this disease are the duration of combination antiretroviral therapy, the use of corticosteroids, alcohol consumption, severe immunosuppression, and high body mass index. Symptoms of osteonecrosis are: stiffness in the joints, pain and discomfort especially in the hips, knees, and shoulders, and difficulty moving. If you notice any of these symptoms, inform your doctor.

Use of other medicines:

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription. These may affect the action of Lamivudine Normon, or Lamivudine Normon may affect their action.

Lamivudine Normon should not be taken with zalcitabine, high doses of cotrimoxazole, or with ganciclovir or foscarnet infusions.

Pregnancy and breastfeeding:

Consult your doctor or pharmacist before taking any medicine. If you become pregnant or plan to become pregnant, you should contact your doctor to discuss the potential adverse effects and the benefits and risks of your antiretroviral therapy for you and your child. Lamivudine Normon is not recommended during the first three months of pregnancy.

If you have taken Lamivudine Normon during your pregnancy, your doctor may require regular visits to monitor the development of your child. These visits may include blood tests and other diagnostic tests.

In children whose mothers took nucleoside and nucleotide analogues during pregnancy, the benefit of reducing the likelihood of being infected with HIV is greater than the risk of suffering adverse effects.

Since lamivudine and the virus pass into breast milk, mothers taking Lamivudine Normon should not breastfeed their children. It is recommended that HIV-infected women do not breastfeed their children under any circumstances to avoid transmitting HIV.

Lamivudine Normon contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per tablet; this is essentially "sodium-free".

3. How to take Lamivudine Normon

Follow exactly the instructions for taking Lamivudine Normon 300 mg given by your doctor. Ask your doctor or pharmacist if you have any doubts. Swallow the Lamivudine Normon 300 mg tablets with water or another drink. These tablets can be taken with or without food.

The usual daily dose of Lamivudine Normon in adults and adolescents over 12 years of age is 300 mg. This dose can be taken as 1 tablet of 150 mg twice a day, approximately every 12 hours, or as 300 mg once a day (2 tablets of 150 mg or 1 tablet of 300 mg).

For children under 12 years of age and weighing less than 30 kg: this formulation is not suitable for achieving the optimal dose.

If you have kidney problems, your dose may be adjusted. Follow your doctor's instructions.

If you take more Lamivudine Normon than you should,it is unlikely that accidentally taking too much Lamivudine Normon will cause serious problems. However, you should inform your doctor or pharmacist, or go to the emergency department of the nearest hospital for advice.

If you have taken more Lamivudine Normon than you should, consult your doctor, pharmacist, or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Lamivudine Normon 300 mg Tablets:If you forget to take a dose of Lamivudine Normon, take it as soon as you remember and then continue as before. Do not take a double dose to make up for forgotten doses.

If you have any other questions about the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Lamivudine Normon 300 mg can cause side effects, although not everybody gets them. When treating HIV infection, it is not always possible to say whether a side effect is caused by Lamivudine Normon, by other medicines you are taking at the same time, or by the HIV disease itself. For this reason, it is very important that you inform your doctor about any change in your health.

The most frequently reported side effects (more than 1 in every 100 patients treated) are nausea, vomiting, stomach pain, diarrhea, headache, joint pain, muscle problems, cough, nasal symptoms (irritation, runny nose), fever, fatigue, general feeling of being unwell, skin rash, hair loss, and difficulty sleeping.

The following side effects are not common (between 1 in every 1,000 and 1 in every 100 patients treated): anemia (low red blood cell count), neutropenia (low white blood cell count), and reductions in the number of platelets (blood cells important for blood clotting). If the number of red blood cells is reduced, you may experience symptoms of fatigue or difficulty breathing. A reduction in the white blood cell count can make you more prone to infection. If you have a low platelet count, you may notice that you bruise more easily. Increases in some liver enzymes have also been observed in blood samples from patients treated with lamivudine.

Rarely, the following side effects have been reported (between 1 in every 10,000 and 1 in every 1,000 patients treated): liver inflammation (hepatitis), pancreas inflammation (pancreatitis), muscle tissue rupture.

Very rarely, the following side effects have been reported (less than 1 in every 10,000 patients treated): numbness, tingling, or weakness in the limbs, severe anemia, and severe neutropenia.

In rare cases, a condition called lactic acidosis has been reported, which is an increase in the production of lactic acid in the body, which can cause dehydration and coma in patients taking NRTIs (for more information, see the section Take special care with Lamivudine Normon 300 mg Tablets).

Combination antiretroviral therapy may cause changes in body shape due to changes in fat distribution. These may include loss of fat from the legs, arms, and face, an increase in fat in the abdomen (belly) and other internal organs, breast enlargement, and accumulation of fat on the back of the neck ("buffalo hump"). At present, the cause and long-term effects on health of these events are not known.

Treatment with a combination of antiretrovirals can also cause an increase in lactic acid and sugar in the blood, hyperlipemia (increase in fat in the blood), and insulin resistance.

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

5. Storage of Lamivudine Normon 300 mg Tablets

Keep out of the sight and reach of children.

Do not store above 25°C.

Expiry date:Do not use Lamivudine Normon after the expiry date stated on the packaging after "EXP". The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Return any unused medicine to a pharmacy for safe disposal. This will help protect the environment.

6. Package Contents and Further Information

Composition of Lamivudine Normon 300 mg Tablets:

The active substance is lamivudine. Each tablet contains 300 mg of lamivudine.

The other ingredients (excipients) are: microcrystalline cellulose, sodium starch glycolate (from potato), magnesium stearate, titanium dioxide (E-171), hypromellose, macrogol 6000, red iron oxide (E-172), and black iron oxide (E-172).

Appearance and package contents:

Lamivudine Normon 300 mg is presented in the form of film-coated tablets. The tablets are gray, elongated, and biconvex. Each package contains 30 tablets.

Marketing authorization holder and manufacturer:

LABORATORIOS NORMON, S.A.

Ronda de Valdecarrizo, 6 – 28760 Tres Cantos – Madrid (Spain)

OTHER PRESENTATIONS

Lamivudine Normon 150 mg film-coated tablets EFG

This leaflet was approved in May 2009

Country of registration
Spain
Active substance
lamivudine
Prescription required
Yes
Manufacturer
Laboratorios Normon S.A.
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
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Online doctors for LAMIVUDINE NORMON 300 mg FILM-COATED TABLETS

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for LAMIVUDINE NORMON 300 mg FILM-COATED TABLETS – subject to medical assessment and local rules.

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Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Antonio Cayatte

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His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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Andrei Popov

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He specialises in diagnosing and treating pain conditions that affect quality of life, including:

Chronic pain lasting more than 3 months.
Migraines and recurring headaches.
Neck, back, lower back, and joint pain.
Post-traumatic pain following injury or surgery.
Nerve-related pain, fibromyalgia, and neuralgia.

In addition to pain management, Dr. Popov helps patients with:

Respiratory infections (colds, bronchitis, pneumonia).
High blood pressure and metabolic conditions such as diabetes.
Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

Dr. Popov’s approach is rooted in evidence-based medicine, combined with individualised care tailored to each patient’s history, lifestyle, and clinical needs.

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You can consult Dr. Ben Harbi for:

General health concerns, prevention, and primary care.
Hypertension, type 1 and type 2 diabetes, metabolic issues.
Cold, cough, flu, respiratory infections, sore throat, fever.
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Lifestyle optimisation: stress, sleep, weight, and diet counselling.

Dr. Ben Harbi offers reliable, accessible medical support through online consultations, helping patients make informed decisions about their health with a clear, structured, and compassionate approach.

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General medicine5 years of experience

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High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
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Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
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Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
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Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

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Mar Tabeshadze

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Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

Diagnostic consultations for suspected endocrine disorders
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Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.

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Maryna Kuznetsova

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dyslipidaemia and lipid metabolism disorders
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Lina Travkina

Family medicine12 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

Preventive consultations and check-up planning.
Medical advice and follow-up consultations.
Test interpretation and diagnostic guidance.
Structured support for undiagnosed complaints.
Second opinion on diagnoses and treatment plans.
Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
Post-operative recovery support and pain management.
Preconception counselling and postpartum support.
Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Dmytro Horobets

Family medicine6 years of experience

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

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Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Svetlana Kolomeeva

Cardiology17 years of experience

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

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High blood pressure, headaches, dizziness, swelling, palpitations.
Diagnosis and management of hypertension, arrhythmias, and tachycardia.
Metabolic syndrome, excess weight, high cholesterol.
Chronic fatigue, insomnia, poor concentration, anxiety.
Respiratory symptoms: colds, flu, sore throat, cough, fever.
Digestive issues: heartburn, bloating, constipation, IBS symptoms.
Chronic conditions: diabetes, thyroid disorders.
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Second opinion and decision-making support.
Cardiovascular disease prevention and metabolic risk reduction.
Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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