This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.

How to use BUSCOPRESC 20 mg INJECTABLE SOLUTION

Introduction

Leaflet: information for the user

Buscopresc 20 mg injectable solution

Butylscopolamine bromide

Read the entire leaflet carefully before starting to use this medicine, as it contains important information for you.

Keep this leaflet, as you may need to read it again.
If you have any questions, consult your doctor or pharmacist.
This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this leaflet. See section 4.

Contents of the leaflet

What is Buscopresc and what is it used for
What you need to know before starting to use Buscopresc
How to use Buscopresc
Possible side effects
Storage of Buscopresc
Package contents and additional information

1. What is Buscopresc and what is it used for

The active ingredient of Buscopresc belongs to a group of medicines called semi-synthetic belladonna alkaloids, quaternary ammonium compounds. It has an antispasmodic effect on the smooth muscle of the gastrointestinal, biliary, and genitourinary tracts.

Buscopresc is used in adults and adolescents over 12 years of age and in children and infants for the treatment of acute spasms of the gastrointestinal, biliary, and genitourinary tracts, including biliary and renal colic. It is also used as an adjunct in diagnostic and therapeutic procedures where spasm may be a problem, such as gastro-duodenal endoscopy and radiology.

2. What you need to know before starting to use Buscopresc

Do not use Buscopresc

If you are allergic to butylscopolamine bromide or any of the other ingredients of this medicine (listed in section 6).
If you have increased eye pressure (narrow-angle glaucoma) and are not being treated.
If you have prostate enlargement.
If you have urinary retention due to any urethro-prostatic pathology.
If you have mechanical stenosis of the gastrointestinal tract (narrowing of the gastrointestinal tract) or pyloric stenosis (narrowing of the pylorus).
If you have paralytic ileus (intestinal paralysis) or obstructive ileus (intestinal obstruction).
If you have megacolon (abnormally enlarged colon).
If you have tachycardia.
If you have myasthenia gravis (a chronic disease characterized by varying degrees of muscle weakness).
In patients being treated with anticoagulant medications, as intramuscular hematomas may occur. In these patients, Buscopresc should be administered subcutaneously or intravenously.

Tell your ophthalmologist if, after administration of Buscopresc, you experience eye pain and redness with vision loss, as you may have undiagnosed narrow-angle glaucoma (an eye disease with increased pressure).

Warnings and precautions

Consult your doctor or pharmacist before starting to use Buscopresc.

Be particularly careful with Buscopresc if you are prone to intestinal or urinary obstructions.

After parenteral administration of Buscopresc, cases of anaphylaxis, including episodes of shock, have been observed. As with all medications that produce this type of reaction, if you are administered Buscopresc, you will be monitored.

If severe abdominal pain of unknown origin persists or worsens, or is accompanied by symptoms such as fever, nausea, vomiting, changes in bowel movements, abdominal pain on palpation, decreased blood pressure, fainting, or blood in the stool, you should consult your doctor immediately.

Cautious use is required in patients with cardiac conditions undergoing parenteral treatment with Buscopresc. Monitoring of these patients is recommended.

Other medicines and Buscopresc

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medication.

You should inform your doctor in case of simultaneous treatment with the following medications:

Medicines for the treatment of depression (tricyclic and tetracyclic antidepressants).
Medicines for the treatment of allergies (antihistamines).
Medicines for the treatment of certain mental disorders (antipsychotics).
Medicines for the treatment of cardiac arrhythmias (quinidine, disopyramide).

Medicines for the treatment of heart failure and/or asthma (digoxin, beta-adrenergics).

Medicines for the treatment of viral infections and/or Parkinson's disease (amantadine).
Medicines for the treatment of nausea/vomiting and/or stomach movement paralysis (dopaminergic antagonists, e.g., metoclopramide).
Other anticholinergic medications (e.g., tiotropium, ipratropium, and atropine-like compounds).

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

The use of Buscopresc is not recommended during pregnancy and breastfeeding.

Driving and using machines

During treatment with Buscopresc 20 mg injectable solution, you may experience undesirable effects such as changes in visual accommodation and dizziness. Do not drive or use machines after parenteral administration of Buscopresc 20 mg injectable solution if you experience these undesirable effects until your vision returns to normal.

Buscopresc contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per ampoule; it is essentially "sodium-free".

3. How to use Buscopresc

Follow the administration instructions for this medicine exactly as indicated by your doctor. If you are unsure, consult your doctor or pharmacist again.

The recommended dose for adults and adolescents over 12 years of age is 1-2 ampoules (20-40 mg), several times a day.

The maximum daily dose should not exceed 100 mg of butylscopolamine bromide (5 ampoules of Buscopresc).

No dose adjustment is required in patients with renal and/or hepatic insufficiency.

It should be administered by slow intravenous injection, intramuscularly, or subcutaneously.

The optimal duration of symptomatic treatment depends on the indication, and short-term treatment is recommended.

Buscopresc should not be administered continuously or for long periods without knowing the cause of abdominal pain.

Use in children and infants

In severe cases, a dose of 0.3-0.6 mg per kg of body weight is recommended, several times a day.

The maximum daily dose should not exceed 1.5 mg of butylscopolamine bromide per kg of body weight.

If you use more Buscopresc than you should

Anticholinergic symptoms (such as urinary retention, dry mouth, skin redness, tachycardia, inhibition of gastrointestinal motility, and transient vision disorders) may occur.

If you have used more Buscopresc than you should, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 91 562 04 20.

Information for the doctor:

If necessary, parasymphathomimetics may be administered. Patients should urgently consult an ophthalmologist in case of glaucoma. Cardiovascular complications should be treated according to standard therapeutic measures. If respiratory paralysis occurs, intubation and artificial respiration will be performed. Catheterization will be performed in case of urinary retention.

In addition, adequate supportive measures will be applied as needed.

If you forget to use Buscopresc

Do not administer a double dose to make up for forgotten doses.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

The side effects described are:

Common (may affect more than 1 in 10 people): visual accommodation disorders, tachycardia, dizziness, dry mouth.
Frequency not known (cannot be estimated from available data): shock caused by a severe allergic reaction, which can be life-threatening (anaphylactic shock with possible fatal outcome), allergic reaction (anaphylactic reaction), difficulty breathing (dyspnea), skin reactions, urticaria, skin rash (exanthema), skin redness (erythema), itching, hypersensitivity, pupil dilation, increased eye pressure, decreased blood pressure, flushing, abnormal sweating, difficulty urinating (urinary retention).

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are possible side effects not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Buscopresc

Keep this medicine out of the sight and reach of children.

No special storage conditions are required.

Do not use this medicine after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medicine in the SIGRE collection point at your pharmacy. If you are unsure, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Package contents and additional information

Composition of Buscopresc

The active ingredient is butylscopolamine bromide. Each 1 ml injectable solution contains 20 mg of butylscopolamine bromide.

The other ingredients are sodium chloride and water for injectable preparations.

Appearance of the product and package contents

Clear solution, from colorless to almost colorless.

It is presented in 1 ml colorless glass ampoules in packs of 6 ampoules and in a clinical pack of 50 ampoules.

Marketing authorization holder

Opella Healthcare Spain, S.L.

C/ Rosselló i Porcel, 21

08016 – Barcelona

Spain

Sanofi Group

Manufacturer

Boehringer Ingelheim España, S.A.

Prat de la Riba, 50

08174 Sant Cugat del Vallès (Barcelona)

Spain

or

Sanofi S.r.l.

Via Valcanello 4,

03012 Anagni (Frosinone)

Italy

Date of the last revision of this leaflet: March 2023

You can access detailed information about this medicine by scanning the QR code included in the packaging and leaflet with your smartphone. You can also access this information at the following internet address:

Square QR code with black and white modules on a white background

https://cima.aemps.es/cima/dochtml/p/18220/P_18220.html

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

Country of registration
Spain
Active substance
butylscopolamine
Prescription required
Yes
Manufacturer
Opella Healthcare Spain S.L.
This information is for reference only and does not constitute medical advice. Always consult a licensed doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
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Active substance: butylscopolamine
Manufacturer: Opella Healthcare Spain S.L.
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Dosage form: INJECTABLE, 20 mg/ml
Active substance: butylscopolamine
Manufacturer: Kalceks As
Prescription required

Alternatives to BUSCOPRESC 20 mg INJECTABLE SOLUTION in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to BUSCOPRESC 20 mg INJECTABLE SOLUTION in Poland

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Marketing authorisation holder (MAH): Opella Healthcare France SAS, T/A Sanofi

Prescription not required

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Dosage form: Solution, 20 mg/ml

Active substance: butylscopolamine

Importer: AS Kalceks

Prescription required

Aurogastro

Dosage form: Tablets, 10 mg

Active substance: butylscopolamine

Importer: APL Swift Services (Malta) Ltd. Generis Farmacêutica, S.A.

Prescription not required

Buscopan forte

Dosage form: Tablets, 20 mg

Active substance: butylscopolamine

Manufacturer: Delpharm Reims

Prescription not required

Scopolan

Dosage form: Tablets, 10 mg

Active substance: butylscopolamine

Manufacturer: Wrocławskie Zakłady Zielarskie "Herbapol" S.A.

Prescription not required

Scopolan

Dosage form: Suppositories, 10 mg

Active substance: butylscopolamine

Manufacturer: Wrocławskie Zakłady Zielarskie "Herbapol" S.A.

Prescription not required

Alternative to BUSCOPRESC 20 mg INJECTABLE SOLUTION in Ukraine

GIOSCINU BUTILBROMID KALCEKS

Dosage form: solution, 20 mg/ml in 1 ml ampoule

Active substance: butylscopolamine

Manufacturer: HBM Farma s.r.o.

Prescription required

Online doctors for BUSCOPRESC 20 mg INJECTABLE SOLUTION

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for BUSCOPRESC 20 mg INJECTABLE SOLUTION – subject to medical assessment and local rules.

5.0(6)

Svetlana Kovalenko

Family medicine14 years of experience

Dr Svetlana Kovalenko is a family medicine doctor with over 14 years of experience and a medical degree from Kharkiv National Medical University. She offers online consultations for adults, supporting patients with both acute and chronic conditions, preventive care, and personalised medical advice.

What patients commonly consult her for:

High blood pressure, type 2 diabetes, cholesterol management
Cold and flu symptoms: fever, cough, sore throat
Fatigue, sleep problems, headaches, general discomfort
Ongoing care for chronic conditions and medication review
Help interpreting test results and lab reports
Preventive check-ups and advice on healthy lifestyle habits

Dr Kovalenko combines evidence-based practice with a respectful, patient-centred approach. She takes time to explain, listens attentively, and helps each person make confident, informed decisions about their health.

Book a video appointment

Tomasz Grzelewski

Dermatology20 years of experience

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

seasonal and perennial allergies
allergic rhinitis and chronic nasal symptoms
asthma and breathing difficulties
food and medication allergies
urticaria, atopic dermatitis and skin reactions
recurrent infections in children
sports-related health questions
general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Lina Travkina

Family medicine12 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

Preventive consultations and check-up planning.
Medical advice and follow-up consultations.
Test interpretation and diagnostic guidance.
Structured support for undiagnosed complaints.
Second opinion on diagnoses and treatment plans.
Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
Post-operative recovery support and pain management.
Preconception counselling and postpartum support.
Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Antonio Cayatte

General medicine43 years of experience

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic.

His clinical background includes:

assessment of sudden or unclear symptoms
ongoing care for chronic conditions
follow-up after hospital discharge
interpretation of test results
medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association.

Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

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Yevgen Yakovenko

General surgery11 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

12+ years of clinical experience in university hospitals in Germany and Spain.
International education: Ukraine – Germany – Spain.
Member of the German Society of Surgeons (BDC).
Certified in radiological diagnostics and robotic surgery.
Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Andrei Popov

General medicine6 years of experience

Dr. Andrei Popov is a licensed pain management specialist and general practitioner based in Spain. He provides expert online care for adults dealing with both chronic and acute pain, as well as a wide range of everyday health concerns.

He specialises in diagnosing and treating pain conditions that affect quality of life, including:

Chronic pain lasting more than 3 months.
Migraines and recurring headaches.
Neck, back, lower back, and joint pain.
Post-traumatic pain following injury or surgery.
Nerve-related pain, fibromyalgia, and neuralgia.

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Respiratory infections (colds, bronchitis, pneumonia).
High blood pressure and metabolic conditions such as diabetes.
Preventive care and routine health check-ups.

Online consultations last up to 30 minutes and include a detailed symptom review, personalised treatment planning, and medical follow-up when needed.

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Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
Leg swelling, chronic fatigue, reduced exercise tolerance.
EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
Post-COVID-19 cardiac monitoring and care.

Endocrinology – Diabetes, thyroid, metabolism:

Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
Individual treatment plans including oral medications and insulin therapy.
GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
Metabolic syndrome – obesity, lipid disorders, insulin resistance.

Gastroenterology – Digestive health:

Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).

General internal medicine and preventive care:

Respiratory infections – cough, colds, bronchitis.
Lab test analysis, therapy adjustments, medication management.
Adult vaccinations – planning, contraindications assessment.
Cancer prevention – screening strategies and risk assessment.
Holistic approach – symptom relief, complication prevention, and quality of life improvement.

Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

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Mar Tabeshadze

Endocrinology10 years of experience

Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

Diagnostic consultations for suspected endocrine disorders
Management of thyroid conditions, including in pregnant women
Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
Diagnosis and treatment of endocrine-related skin, hair, and nail issues
Ongoing care for patients with osteoporosis, pituitary, and adrenal gland disorders

Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.

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Alina Tsurkan

Family medicine12 years of experience

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
Chronic diseases: hypertension, elevated cholesterol, weight management.
Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

IMT medical certificates for driving licence exchange in Portugal.
Personalised preventive care and wellness consultations.
Interpretation of test results and medical reports.
Follow-up care and medication review.
Support in managing multiple coexisting conditions.
Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Maryna Kuznetsova

Cardiology16 years of experience

Dr Marina Kuznetsova is an internal medicine doctor and cardiologist with a PhD in medicine. She provides online consultations for adults with chronic and acute conditions, with a strong focus on cardiovascular health. Her approach is based on current clinical guidelines and evidence-based treatment strategies.

Areas of expertise: