Bg pattern

SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Sinetrav 40 micrograms/ml eye drops, solution

Travoprost

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again. If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is Sinetrav and what is it used for
  2. What you need to know before you use Sinetrav
  3. How to use Sinetrav
  4. Possible side effects
  5. Storage of Sinetrav
  6. Contents of the pack and other information

1. What is Sinetrav and what is it used for

Sinetrav contains travoprost, a prostaglandin analogue. It works by reducing the pressure in the eye. It can be used alone or together with other eye drops, such as beta-blockers, which also reduce pressure.

Sinetrav is used to reduce high pressure in the eye in adults, adolescents, and children from 2 months of age.This pressure can cause a disease called glaucoma.

Sinetrav eye drops, solution is a sterile solution that does not contain preservatives.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Sinetrav

Do not use Sinetrav

  • If you are allergic to travoprost or any of the other ingredients of this medicine (listed in section 6).

Talk to your doctor if you are in this situation.

Warnings and precautions

  • Sinetrav may increase the length, thickness, color, and/or number of your eyelashes. Changes such as unusual hair growth on the eyelids or around the eye have also been observed.
  • Sinetrav may change the color of your iris (the colored part of the eye). This change may be permanent. It can also cause a change in the color of the skin around the eye.
  • If you have had cataract surgery, talk to your doctor before starting to use Sinetrav.
  • If you have or have had eye inflammation (iritis or uveitis), talk to your doctor before starting to use Sinetrav.
  • Sinetrav may, in rare cases, cause difficulty breathing or wheezing or increase asthma symptoms. If you are concerned about changes in your breathing while using this medicine, talk to your doctor as soon as possible.
  • Sinetrav may be absorbed through the skin. In case of contact of the medicine with the skin, it should be removed by washing immediately. This is especially important in pregnant or breastfeeding women.
  • If you wear contact lenses, do not apply the drops while wearing them. After applying the drops, wait 15 minutes before putting the contact lenses back in.

Children and adolescents

Sinetrav can be used in children from 2 months of age to <18 years with the same dose as in adults. use of sinetrav is not recommended children under 2 months age.< p>

Other medicines and Sinetrav

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Pregnancy, breastfeeding, and fertility

Do not use Sinetrav if you are pregnant.If you think you might be pregnant, talk to your doctor as soon as possible. If you can become pregnant, you must use adequate contraceptive measures while using this medicine.

Do not use Sinetrav if you are breastfeeding.This medicine may pass into breast milk.

If you are pregnant or breastfeeding, think you might be pregnant, or plan to become pregnant, talk to your doctor before using this medicine.

Driving and using machines

You may notice that your vision becomes blurry for a while immediately after applying Sinetrav. Do not drive or use machines until these effects have disappeared.

Sinetrav contains macrogolglycerol hydroxystearate 40

This medicine may cause skin reactions because it contains macrogolglycerol hydroxystearate 40.

3. How to use Sinetrav

Follow the instructions for administration of this medicine exactly as indicated by your doctor or the doctor treating the child. If in doubt, consult your doctor, the doctor treating the child, or the pharmacist again.

Sinetrav should only be used as eye drops.

The recommended dose is 1 drop in the affected eye(s) once a day, at night.

Use Sinetrav in both eyes only if your doctor has told you to do so.

Use this medicine for the time indicated by your doctor or the doctor treating the child.

Instructions for use

Needle with removable transparent protector on a white cylinder with lower marked rings

1a

Hands holding a vial and a nasal applicator with an arrow indicating connection of the applicator to the vial

1b

  • Take the multidose container (image 1a)out of the box and write the opening date on the space on the box and label designed for this purpose.
  • Take the medicine and a mirror.
  • Wash your hands.
  • Remove the cap (image 1b).

Hand holding an inhaler with the mouthpiece pointing downwards and an arrow indicating the direction of the shot2

  • Hold the bottle upside down with your thumb on the bottle's protrusion and your other fingers on the bottom of the bottle. Before the first use, press the bottle repeatedly, about 10 times, until the first drop appears. (image 2).

Hand holding the lower eyelid of the open eye with index and middle fingers

3

  • Tilt your head or the child's head back. Pull the lower eyelid down with a clean finger, until a "pocket" is formed between your eyelid and eye. The drop should be placed there (image 3).
  • Bring the bottle close to the eye. Use a mirror to help you.

Hand applying eye drops to the open eye of a person, white bottle tilted near the lower eyelid

4

Index finger gently pressing on the lower eyelid of the closed eye with visible eyelashes

5

  • Do not touch the eye, eyelid, or surrounding areas with the dropper tip. The drops could become infected.
  • Gently squeeze the bottom of the container to release one drop of medicine at a time (image 4).
  • If the drop does not fall into the eye, repeat the process.
  • After using the medicine, press the edge of the eye, next to the nose (image 5). This helps prevent the medicine from passing into the rest of the body.
  • If you apply drops in both eyes, repeat the same steps in the other eye.
  • Close the multidose container cap tightly immediately after use.
  • Use one container of medicine at a time. Do not open the cap until you need to use the multidose container.
  • You must discard the bottle 4 weeks after the first openingto prevent infections, and use a new bottle.

If you use more Sinetrav than you should

Remove the medicine by washing the eye with lukewarm water. Do not apply more drops until it is time for your next dose.

In case of overdose or accidental ingestion, talk to your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to use Sinetrav

Continue with the next scheduled dose. Do not apply a double dose to make up for forgotten doses. Never apply more than one drop in the affected eye(s) on the same day.

If you stop using Sinetrav

Do not stop using this medicine without talking to your doctor or the doctor treating the child. This is because the pressure in your eye or your child's eye will not be controlled, which could lead to loss of vision.

If you or the child are using other eye medicines, such as eye drops or ointments for the eyes

Wait at least 5 minutes between applying Sinetrav and other eye medicines.

If you have any other questions about the use of this medicine, ask your doctor, the doctor treating the child, or the pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

You can normally continue your treatment as long as the side effects are not serious. If these effects worry you, talk to your doctor or pharmacist. Do not stop using Sinetrav without talking to your doctor.

The following side effects have been observed with the use of travoprost.

Very common side effects(may affect more than 1 in 10 people)

Eye effects:

  • eye redness.

Common side effects(may affect up to 1 in 10 people)

Eye effects:

  • changes in iris color (colored part of the eye)
  • eye pain
  • eye discomfort
  • dry eye
  • eye itching
  • eye irritation

Uncommon side effects(may affect up to 1 in 100 people)

Eye effects:

  • corneal disorder
  • eye inflammation
  • iris inflammation
  • inflammation inside the eye
  • inflammation with or without damage to the eye surface
  • sensitivity to light
  • eye discharge
  • eyelid inflammation
  • eyelid redness
  • swelling around the eye
  • eyelid itching
  • blurred vision
  • increased tear production
  • conjunctivitis (inflammation or infection of the conjunctiva)
  • abnormal turning out of the lower eyelid
  • shadowy vision
  • eyelid crusts
  • eyelash growth

General side effects:

  • increased allergic symptoms
  • headache
  • irregular heartbeat
  • cough
  • stuffy nose
  • throat irritation
  • darkening of the skin around the eye(s)
  • darkening of the skin
  • abnormal hair texture
  • excessive hair growth

Rare side effects(may affect up to 1 in 1,000 people)

Eye effects:

  • iridocyclitis
  • perception of flashes of light
  • eyelid eczema
  • abnormally positioned eyelashes that grow towards the eye
  • eye swelling
  • reduced vision
  • vision of halos
  • decreased sensitivity in the eye
  • inflammation of the eyelid glands
  • pigmentation inside the eye
  • increased pupil size
  • thickening of eyelashes
  • change in eyelash color
  • tired eyes

General side effects:

  • eye viral infection
  • dizziness
  • bad taste in the mouth
  • irregular or decreased heartbeat
  • increased or decreased blood pressure
  • difficult breathing
  • asthma
  • nasal allergy or inflammation
  • nasal dryness
  • voice changes
  • stomach ulcers or discomfort
  • constipation
  • dry mouth
  • skin redness or itching
  • rash
  • change in hair color
  • loss of eyelashes
  • joint pain
  • musculoskeletal pain
  • general weakness

Frequency not known(frequency cannot be estimated from the available data)

Eye effects:

  • inflammation of the back of the eye
  • sunken eyelid fold

General side effects:

  • depression
  • anxiety
  • insomnia
  • false sense of movement
  • ringing in the ears
  • chest pain
  • heart rhythm disorder
  • increased heart rate
  • worsening of asthma
  • diarrhea
  • nosebleeds
  • abdominal pain
  • nausea
  • vomiting
  • itching
  • abnormal hair growth
  • painful or involuntary urination
  • increase in prostate cancer marker

In children and adolescents, the most common side effects observed with travoprost are eye redness and eyelash growth. Both side effects were observed with a higher incidence in children and adolescents compared to adults.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System for Human Use: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Sinetrav

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the bottle and carton, after "EXP". The expiry date is the last day of the month shown.

Do not use this medicine if you notice that the multidose container is broken or damaged before you first open it.

Store below 25°C.

After opening, this medicine does not require any special storage conditions.

To avoid infections, you must discard the bottle 4 weeks after first opening. Write the opening date on the space provided on the carton and bottle.

Medicines should not be disposed of via wastewater or household waste. Return the containers and medicines you no longer need to the pharmacy's SIGRE Point. If in doubt, ask your pharmacist how to dispose of the containers and medicines you no longer need. This will help protect the environment.

6. Contents of the pack and other information

Composition of Sinetrav

  • The active substance is travoprost. Each ml of solution contains 40 micrograms of travoprost.
  • The other ingredients are macrogolglycerol hydroxystearate 40, sodium chloride, propylene glycol (E-1520), boric acid (E-284), mannitol (E-421), sodium hydroxide to adjust pH, and purified water.

Appearance of the product and contents of the pack

Sinetrav is a clear and transparent solution of 2.5 ml, presented in a cardboard box containing a multidose container (PP) white 5 ml with a pump system (PP, HDPE, LDPE), a green pressure cylinder, and a cap (HDPE).

The product is available in the following pack sizes:

1 x 2.5 ml (one 2.5 ml multidose container)

3 x 2.5 ml (three 2.5 ml multidose containers)

The boxes contain 1 or 3 bottles.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Horus Pharma

22 Allée Camille Muffat

INEDI 5

06200 Nice, France

Manufacturer

JADRAN GALENSKI LABORATORIJ D.D

Svilno, 20

51000 Rijeka, Croatia

Or

Pharmathen S.A.

6, Dervenakion Str

GR-15351, Pallini Attikis, Greece

Local representative

HORUS PHARMA IBÉRICA, S.L.U

Gran Vía Carlos III, 98, 6º

08028 Barcelona –

Date of last revision of this leaflet:July 2021

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION

Discuss questions about SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (4)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (144)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50
5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55
5.0 (32)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60

Frequently Asked Questions

Is a prescription required for SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION?
SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION?
The active ingredient in SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION is travoprost. This information helps identify medicines with the same composition but different brand names.
How much does SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION cost in pharmacies?
The average pharmacy price for SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION is around 13.35 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION?
SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION is manufactured by Horus Pharma. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to SINETRAV 40 MICROGRAMS/ML EYE DROPS SOLUTION?
Other medicines with the same active substance (travoprost) include LEACHIM 40 MICROGRAMS/ML EYE DROPS IN SOLUTION, TAVLIANT 40 micrograms/ml eye drops solution, TRAGLASIN 40 micrograms/ml eye drops solution in single-dose containers. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media