Bg pattern

ROCALTROL 0.25 mcg SOFT GEL CAPSULES

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ROCALTROL 0.25 mcg SOFT GEL CAPSULES

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Rocaltrol 0.25 micrograms soft capsules

Calcitriol

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is Rocaltrol and what is it used for
  2. What you need to know before you take Rocaltrol
  3. How to take Rocaltrol
  4. Possible side effects
  5. Storage of Rocaltrol
  6. Contents of the pack and other information

1. What is Rocaltrol and what is it used for

Rocaltrol contains the active substance calcitriol, (a derivative of vitamin D3) which promotes intestinal absorption of calcium and regulates bone mineralization.

Your doctor will prescribe Rocaltrol if your kidneys cannot synthesize calcitriol correctly, which can occur if you suffer from:

  • Renal osteodystrophy (decalcification of bones due to chronic renal failure).
  • Post-surgical or idiopathic hypoparathyroidism (deficiency of parathyroid hormone that causes abnormal levels of calcium and phosphorus in the blood).
  • Pseudo-hypoparathyroidism (genetic disorder that resembles hypoparathyroidism but is caused by the body's lack of response to parathyroid hormone and not because the levels of this hormone are low).
  • Osteomalacia (softening and weakening of bones).
  • Rickets (osteomalacia in children) dependent on vitamin D (due to alterations in vitamin D metabolism or its receptors) or hypophosphatemic resistant to vitamin D (due to renal loss of phosphate).
  • Pre-surgical treatment in primary hyperparathyroidism (elevated levels of parathyroid hormone due to parathyroid gland enlargement), to minimize postoperative hypocalcemia (decrease in blood calcium levels).
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Rocaltrol

Do not take Rocaltrol:

  • If you are allergic to calcitriol or any of the other components of this medicine (listed in section 6).
  • If you have high levels of calcium in the blood.
  • If you have vitamin D poisoning.

Warnings and precautions

Consult your doctor or pharmacist before starting to take Rocaltrol.

Be especially careful with Rocaltrol:

  • If you have to be immobilized, for example after an operation, as you may be at greater risk of hypercalcemia (high levels of calcium in the blood).
  • If you have renal failure, as you are at greater risk of calcification.
  • If you have vitamin D-resistant rickets (familial hypophosphatemia), as it may be necessary to modify the need for phosphate supplements.
  • Follow the dietary measures recommended by your doctor. If your doctor has not recommended it, do not take other calcium preparations that are not subject to medical prescription on your own.
  • Your doctor will perform periodic checks to control calcium levels in case the dose needs to be adjusted.
  • Avoid taking vitamin D or its derivatives (such as dihydrotachysterol) at the same time, as hypercalcemia may occur.

Children

The safety and efficacy of Rocaltrol in children have not been established to make a dosage recommendation.

Other medicines and Rocaltrol

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Note that:

  • If you are being treated with digoxin or similar medicines (for heart failure and abnormal heart rate), arrhythmias due to hypercalcemia may appear.
  • If you have vitamin D-resistant rickets and are being treated with oral phosphate, your doctor may need to adjust your phosphate supplement intake.
  • If you are being treated with thiazide diuretics (for hypertension), as they increase the risk of hypercalcemia (high levels of calcium in the blood).
  • If you are taking cholestyramine (a medicine to lower cholesterol and fat levels in the blood) or sevelamer (a medicine to lower phosphate levels in the blood), as they alter the intestinal absorption of calcitriol.
  • If you are undergoing chronic renal dialysis, you should avoid taking medicines that contain magnesium (such as antacids), as they may lead to hypermagnesemia (elevated levels of magnesium in the blood).
  • If you are taking corticosteroids, as they may counteract the effects of vitamin D analogs.

Taking Rocaltrol with food and drinks

If your renal function is normal, you should drink liquids adequately to avoid dehydration. Follow the dietary measures recommended by your doctor. If your doctor has not recommended it, do not take other calcium preparations that are not subject to medical prescription on your own.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Your doctor will decide whether it is convenient for you to take Rocaltrol. Taking Rocaltrol during breastfeeding requires monitoring of serum calcium levels in the mother and child.

Driving and using machines

This medicine does not affect your ability to drive or use machines.

Rocaltrol contains sorbitol

This medicine contains 2.87 - 4.37 mg of sorbitol in each 0.25 mcg capsule.

3. How to take Rocaltrol

Follow your doctor's instructions for taking this medicine exactly. If you are in doubt, consult your doctor again.

Normal dose:

Your doctor will determine the optimal dose of Rocaltrol based on your blood calcium levels. To do this, they will perform analyses at least twice a week.

Once your dose has been determined, your doctor will check your blood calcium levels monthly. If the normal levels of calcium are exceeded, your doctor will reduce the dose of Rocaltrol or interrupt treatment until normal calcium levels are restored in the blood.

For the treatment with Rocaltrol to be optimal, it is necessary that the calcium intake in the diet is adequate. If necessary, your doctor will prescribe a calcium supplement. It is essential that you strictly follow the diet prescribed by your doctor, as a sudden increase in calcium intake can trigger hypercalcemia (high levels of calcium in the blood).

Dose in other diseases:

Renal osteodystrophy (dialyzed patients)

The initial daily dose is 0.25 micrograms. If your blood calcium levels are normal or moderately low, this dose will be sufficient every two days. If your doctor does not register the expected improvement, they may increase the dose, with intervals of two to four weeks, by 0.25 micrograms daily each time. During this period, your doctor will determine your blood calcium levels at least twice a week.

Most patients respond to doses between 0.5 and 1.0 micrograms per day. It may be necessary to take higher doses when barbiturates or anticonvulsants are administered at the same time.

Hypoparathyroidism and rickets

The recommended initial dose is 0.25 micrograms per day, administered in the morning.

Similarly, if your doctor considers it appropriate, they will increase your dose at intervals of two to four weeks. During the dose adjustment period, your doctor will determine your blood calcium levels at least twice a week.

In patients with hypoparathyroidism, poor absorption is occasionally observed; it may then be necessary to administer higher doses of Rocaltrol.

If you take more Rocaltrol than you should

Since calcitriol is a derivative of vitamin D, the symptoms of a calcitriol overdose are the same as those of a vitamin D overdose. These same symptoms can occur if you take high doses of calcium and phosphate while being treated with Rocaltrol.

The acute symptoms of calcitriol intoxication are: anorexia (loss of appetite), headache, vomiting, and constipation. The chronic symptoms are dystrophy (progressive muscle weakness), sensory disorders, fever with thirst, polyuria (increased urine excretion), dehydration, apathy (lack of energy), growth interruption, and urinary tract infections. Hypercalcemia (high levels of calcium in the blood) can be followed by metastatic calcification of the renal cortex, myocardium, lungs, and pancreas (calcium accumulates in these tissues, causing them to harden).

Treatment will be with emesis (induction of vomiting) or gastric lavage to prevent intestinal absorption of calcium. Liquid paraffin may also be administered to induce fecal excretion. Repeated analyses of blood calcium are recommended. If elevated calcium levels persist, force urinary excretion with phosphates or corticosteroids.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or go to a medical center, or contact the Toxicology Information Service, Telephone (91) 562.04.20, indicating the medicine and the amount ingested.

If you forget to take Rocaltrol

Do not take a double dose to make up for forgotten doses.

If you stop taking Rocaltrol

Your doctor will indicate the duration of your treatment with Rocaltrol. Do not stop treatment before.

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, Rocaltrol can cause side effects, although not everybody gets them.

The side effects are similar to those observed when taking excessive doses of vitamin D, i.e., hypercalcemia syndrome (high levels of calcium in the blood) or calcium poisoning.

The side effects observed with calcitriol are the following:

Very common side effects(may affect more than 1 in 10 people)

  • Hypercalcemia (high levels of calcium in the blood)

Common side effects(may affect up to 1 in 10 people)

  • Headache
  • Nausea
  • Abdominal pain or stomach pain
  • Urinary tract infections
  • Rash

Uncommon side effects(may affect up to 1 in 100 people):

  • Anorexia (loss of appetite)
  • Vomiting
  • Increased creatinine in the blood

Side effects with unknown frequency(cannot be estimated from the available data):

  • Hypersensitivity (allergy)
  • Urticaria (hives, usually with itching of the skin)
  • Polydipsia (increased thirst)
  • Dehydration
  • Apathy (lack of energy)
  • Psychiatric disorders
  • Muscle weakness
  • Sensory disorders
  • Insomnia (difficulty sleeping)
  • Cardiac arrhythmias (irregular heartbeats)
  • Constipation
  • Pain in the upper abdomen
  • Paralytic ileus (intestinal obstruction)
  • Erythema (inflamed and reddened skin)
  • Pruritus (itching)
  • Growth retardation
  • Polyuria (increased urine excretion)
  • Nocturia (need to urinate at night)
  • Calcinosis (calcium deposits in tissues)
  • Fever with thirst
  • Thirst
  • Weight loss

Reporting of side effects:

If you experience any side effects, talk to your doctor or pharmacist, even if it is not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Rocaltrol

Keep this medicine out of the sight and reach of children.

Do not store above 25°C. Keep the blister pack in the outer packaging to protect it from light and moisture.

Do not use this medicine after the expiry date stated on the carton after EXP. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

Composition of Rocaltrol 0.25 micrograms:

  • The active substance is calcitriol. Each Rocaltrol soft capsule contains 0.25 micrograms of calcitriol.
  • The other components are:

Capsule content: butylhydroxyanisole (E-320), butylhydroxytoluene (E-321), medium-chain triglycerides.

Capsule shell: gelatin, glycerol 85%, karion 83 (contains: sorbitol (E-420), mannitol, and hydrogenated corn starch hydrolyzate), titanium dioxide (E-171), red and yellow iron oxide (E-172).

Appearance of the product and pack contents

Rocaltrol 0.25 micrograms soft capsules are oval-shaped, with one half being brown-orange to orange-red opaque and the other half being white to light yellow or gray-orange opaque.

This medicine is presented in PVC blisters containing 20 soft capsules.

Marketing authorization holder and manufacturer

Marketing authorization holder

ATNAHS PHARMA NETHERLANDS B.V.

Copenhagen Towers, Ørestads Boulevard 108, 5.tv

DK-2300 København S

Denmark

Manufacturer

IL CSM Clinical Supplies Management GmbH

Marie-Curie-Strasse 8

Lörrach

Baden-Württemberg, 79539

Germany

or

allphamed PHARBIL Arzneimittel GmbH

Hildebrandstr. 10-12,

Goettingen, Lower Saxony, 37081, Germany

Local representative

Laboratorios Rubió, S.A.

Industria, 29 - Pol. Ind. Comte de Sert

08755 Castellbisbal (Barcelona)

Spain

Date of last revision of this leaflet:January 2021.

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for ROCALTROL 0.25 mcg SOFT GEL CAPSULES

Discuss questions about ROCALTROL 0.25 mcg SOFT GEL CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (140)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50
5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
Camera Book a video appointment
€60
5.0 (29)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60
5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55
5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for ROCALTROL 0.25 mcg SOFT GEL CAPSULES?
ROCALTROL 0.25 mcg SOFT GEL CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ROCALTROL 0.25 mcg SOFT GEL CAPSULES?
The active ingredient in ROCALTROL 0.25 mcg SOFT GEL CAPSULES is calcitriol. This information helps identify medicines with the same composition but different brand names.
Who manufactures ROCALTROL 0.25 mcg SOFT GEL CAPSULES?
ROCALTROL 0.25 mcg SOFT GEL CAPSULES is manufactured by Atnahs Pharma Netherlands Bv.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ROCALTROL 0.25 mcg SOFT GEL CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ROCALTROL 0.25 mcg SOFT GEL CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ROCALTROL 0.25 mcg SOFT GEL CAPSULES?
Other medicines with the same active substance (calcitriol) include ROCALTROL 0.50 mcg SOFT GEL CAPSULES, ALDEXINA 25,000 IU HARD CAPSULES, ALDEXINA 50,000 IU HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media