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Holestil

Ask a doctor about a prescription for Holestil

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Doctor

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use Holestil

Package Leaflet: Information for the Patient

Cholestil, 200 mg, Tablets

Hymecromone

Read the package leaflet carefully before taking the medicine, as it contains important information for the patient.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, including any not listed in this leaflet, tell your doctor, pharmacist, or nurse. See section 4.

Table of Contents of the Leaflet

  • 1. What is Cholestil and what is it used for
  • 2. Important information before taking Cholestil
  • 3. How to take Cholestil
  • 4. Possible side effects
  • 5. How to store Cholestil
  • 6. Contents of the pack and other information

1. What is Cholestil and what is it used for

Hymecromone is a coumarin derivative. It has a spasmolytic effect on the smooth muscle of the bile ducts and the Oddi sphincter, increases bile secretion, and accelerates its elimination through the bile ducts. This action reduces bile stasis and related symptoms, as well as prevents the formation of cholesterol deposits and gallstones.

  • as an auxiliary treatment for symptomatic treatment of spastic conditions of the bile ducts, dyskinesia, dyspeptic disorders,
  • functional disorders of the bile ducts in patients with uncomplicated cholelithiasis,
  • post-operative conditions of the gallbladder and bile ducts, as well as in cases of decreased appetite, nausea, and constipation related to reduced bile secretion.

2. Important information before taking Cholestil

When not to take Cholestil:

  • if you are allergic to hymecromone or any of the other ingredients of this medicine (listed in section 6);
  • if you have bile duct obstruction;
  • if you have severe liver and/or kidney failure;
  • in patients with ulcerative colitis and Crohn's disease.

Warnings and precautions

Before taking Cholestil, discuss it with your doctor, pharmacist, or nurse. If you experience symptoms of liver and/or kidney failure, stop taking the medicine. Consult your doctor, even if the above warnings refer to past situations.

Cholestil and other medicines

Tell your doctor or pharmacist about all medicines you are taking, or have recently taken, and about any medicines you plan to take.

  • Morphine reduces the effect of hymecromone.
  • When taking hymecromone with metoclopramide, the effect of both medicines is reduced.

Taking Cholestil with food and drink

Take the medicine half an hour before meals.

Cholestil in patients with kidney and/or liver disorders

Do not use the medicine in patients with liver and/or kidney failure.

Cholestil in elderly patients

There is no need to change the dosage in elderly patients.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine. There is no data on the safety of using the medicine during pregnancy. Administration of hymecromone to pregnant women is only justified when the benefit to the mother outweighs the potential risk to the fetus. There is no data on the safety of using the medicine during breastfeeding. It is not recommended to use the medicine during breastfeeding.

Driving and using machines

The medicine does not affect psychophysical abilities, the ability to drive vehicles, and operate machinery.

Cholestil contains sodium

The medicine contains less than 1 mmol (23 mg) of sodium per tablet, which means the medicine is considered "sodium-free".

3. How to take Cholestil

Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist. Adults: 200 to 400 mg (1 to 2 tablets) half an hour before meals, three times a day, for two weeks. Do not divide the tablets. If you feel that the effect of Cholestil is too strong or too weak, ask your doctor.

Taking more Cholestil than prescribed

There is no data on overdose. If you have taken more than the prescribed dose, contact your doctor or pharmacist immediately.

Missing a dose of Cholestil

Take the missed dose as soon as possible. Do not take a double dose to make up for the missed dose. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Cholestil can cause side effects, although not everybody gets them. Cholestil is generally well-tolerated. Diarrhea, feeling of fullness or pressure in the abdominal cavity, hypersensitivity reactions may occur. If you experience any side effects, including any not listed in this leaflet, tell your doctor, pharmacist, or nurse.

Reporting side effects

If you experience any side effects, including any not listed in this leaflet, tell your doctor, pharmacist, or nurse. Side effects can be reported directly to the Department of Monitoring of Adverse Reactions to Medicinal Products of the Office for Registration of Medicinal Products, Medical Devices, and Biocidal Products: Al. Jerozolimskie 181C, 02-222 Warsaw, tel.: +48 22 49 21 301, fax: +48 22 49 21 309, website: https://smz.ezdrowie.gov.pl. Side effects can also be reported to the marketing authorization holder. By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Cholestil

Keep the medicine out of the sight and reach of children. Store in the original package. Store at a temperature below 25°C. Do not use this medicine after the expiry date stated on the package after EXP. The expiry date refers to the last day of the month stated. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

What Cholestil contains

The active substance is hymecromone. One tablet contains 200 mg of hymecromone. The other ingredients are: potato starch, gelatin (type A), sodium lauryl sulfate, magnesium stearate.

What Cholestil looks like and contents of the pack

White or white with a yellowish tint, round, flat on both sides, tablets engraved with "Ch" on one side. The tablets are packaged in PVC/Al blisters or a polyethylene container in a cardboard box with a patient leaflet. The pack contains 50 tablets.

Marketing authorization holder

Adamed Pharma S.A. Pieńków, ul. M. Adamkiewicza 6A 05-152 Czosnów

Manufacturer

Adamed Pharma S.A. Pieńków, ul. M. Adamkiewicza 6A 05-152 Czosnów Date of last revision of the leaflet:

Alternatives to Holestil in other countries

The best alternatives with the same active ingredient and therapeutic effect.

Alternative to Holestil in Ukraine

Dosage form: tablets, tablets 200mg
Active substance: hymecromone
Manufacturer: Adamed Farma S.A.
Prescription not required
Dosage form: capsules, 10 capsules in a blister
Dosage form: tablets, 30 tablets in a blister
Prescription not required
Dosage form: tincture, 100 ml in a bottle
Prescription not required
Dosage form: flowers, 75 g in packs
Manufacturer: PrAT "Liktravi
Prescription not required
Dosage form: collection, 50 g in packs
Manufacturer: PrAT "Liktravi
Prescription not required

Alternative to Holestil in Spain

Dosage form: CAPSULE, 150 mg
Prescription not required
Dosage form: CAPSULE, 10 mg
Prescription required
Dosage form: ORAL SOLUTION/SUSPENSION, 9.5 MG/ML
Active substance: maralixibat chloride
Prescription required
Dosage form: CAPSULE, 600 µg
Active substance: odevixibat
Manufacturer: Ipsen Pharma
Prescription required
Dosage form: CAPSULE, 200 - REVIEW µg
Active substance: odevixibat
Manufacturer: Ipsen Pharma
Prescription required
Dosage form: CAPSULE, 200 µg
Active substance: odevixibat
Manufacturer: Ipsen Pharma
Prescription required

Online doctors for Holestil

Discuss dosage, side effects, interactions, contraindications, and prescription renewal for Holestil – subject to medical assessment and local rules.

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Doctor

Maryna Kuznetsova

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Dr Marina Kuznetsova is an internal medicine doctor and cardiologist with a PhD in medicine. She provides online consultations for adults with chronic and acute conditions, with a strong focus on cardiovascular health. Her approach is based on current clinical guidelines and evidence-based treatment strategies.

Areas of expertise:

  • dyslipidaemia and lipid metabolism disorders
  • prevention and management of atherosclerosis
  • blood pressure monitoring and antihypertensive therapy
  • arrhythmias: diagnosis, follow-up, and treatment adjustment
  • cardiovascular care and recovery support after Covid-19
Dr Kuznetsova helps patients manage cardiovascular risk factors, optimise long-term treatment, and gain clarity in complex health situations – all through accessible and structured online care.
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Doctor

Anna Biriukova

General medicine5 years of experience

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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She treats adults with respiratory illnesses such as pneumonia, COPD and bronchial asthma, as well as cardiovascular conditions including hypertension and ischaemic heart disease. Her practice also covers gastrointestinal complaints and chronic comorbidities that require careful, structured medical supervision.

Dr Boichuk provides care for children from birth, including acute respiratory viral infections, infectious diseases, pneumonia, bronchitis, bronchial obstruction syndromes and allergic reactions. She offers clear, evidence-based guidance to parents and ensures safe follow-up throughout the child’s recovery.

Her work also includes developing personalised immunisation plans and supporting families with long-term preventive care.

Known for her structured clinical approach and clear communication, Dr Liudmyla Boichuk offers patients of all ages comprehensive, reliable and evidence-based medical care.

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Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Mar Tabeshadze

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Dr. Mar Tabeshadze is a licensed endocrinologist and general practitioner in Spain. She provides online consultations for adults, offering medical support for a wide range of endocrine conditions and related health concerns.

  • Diagnostic consultations for suspected endocrine disorders
  • Management of thyroid conditions, including in pregnant women
  • Early detection and treatment of type 1 and type 2 diabetes, with personalised therapy plans
  • Obesity treatment: identifying underlying causes of weight gain, combining medication and non-pharmacological strategies, and long-term support
  • Diagnosis and treatment of endocrine-related skin, hair, and nail issues
  • Ongoing care for patients with osteoporosis, pituitary, and adrenal gland disorders
Dr. Tabeshadze takes a patient-centred approach based on evidence-based medicine. Her goal is to help patients achieve hormonal balance, manage chronic conditions effectively, and improve overall well-being through targeted, personalised care.
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Dr Alexandra Alexandrova is a licensed general medicine doctor in Spain, specialising in trichology, nutrition, and aesthetic medicine. She offers online consultations for adults, combining a therapeutic approach with personalised care for hair, scalp, and overall health.

Areas of expertise:

  • Hair loss in women and men, postpartum hair loss, androgenetic and telogen effluvium.
  • Scalp conditions: seborrheic dermatitis, psoriasis, scalp irritation, dandruff.
  • Chronic conditions: hypertension, diabetes, metabolic disorders.
  • Online trichology consultation: customised treatment plans, nutritional support, hair growth stimulation.
  • Hair loss prevention: hormonal imbalance, stress factors, haircare strategies.
  • Routine health check-ups, prevention of cardiovascular and metabolic diseases.
  • Personalised nutritional advice to improve hair strength, skin health, and hormonal balance.
  • Aesthetic medicine: non-invasive strategies to enhance skin quality, tone, and metabolic wellness.

Dr Alexandrova follows an evidence-based and holistic approach: online consultations with a therapist and trichologist on Oladoctor provide professional support for hair, scalp, and overall health — all from the comfort of your home.

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