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PYRAZINAMIDE PRODES 250 mg TABLETS

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5.0 (188)
Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use PYRAZINAMIDE PRODES 250 mg TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Pirazinamida Prodes 250 mg Tablets

pirazinamida

Read the entire package leaflet carefully before starting to take this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Pirazinamida Prodes and what is it used for
  2. What you need to know before taking Pirazinamida Prodes
  3. How to take Pirazinamida Prodes
  4. Possible side effects
  5. Storage of Pirazinamida Prodes
  6. Package Contents and Additional Information

1. What is Pirazinamida Prodes and what is it used for

Pirazinamida Prodes is a medication that belongs to the group of medications called antitubercular agents.

Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or common cold.

It is essential to follow the instructions regarding dosage, administration interval, and treatment duration as indicated by your doctor.

Do not store or reuse this medication. If you have any leftover antibiotic after completing treatment, return it to the pharmacy for proper disposal. Do not throw medications down the drain or in the trash.

Pirazinamida Prodes is used, in combination with other antitubercular medications, in the initial phase of tuberculosis treatment, which usually lasts 2 months.

.

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2. What you need to know before taking Pirazinamida Prodes

Do not take Pirazinamida Prodes:

  • if you are allergic to pirazinamida or any of the other components of this medication (listed in section 6).
  • if you have acute liver problems or have had a previous liver problem caused by medication use,
  • if you have severe kidney problems,
  • if you have hyperuricemia (elevated uric acid levels in the blood) or a history of gout, as this medication decreases uric acid elimination.
  • if you have been diagnosed with a condition called porphyria.

Do not take Pirazinamida Prodes if you are in any of the above circumstances.

Warnings and Precautions

Consult your doctor or pharmacist before starting to take Pirazinamida Prodes.

Before starting to take this medication, inform your doctor if you have any of the following conditions:

  • liver problems and chronic liver disease,
  • kidney problems,
  • gout,
  • diabetes mellitus,
  • porphyria.

Inform your doctor if you are pregnant or think you may be pregnant.

Do not interrupt treatment with Pirazinamida Prodes without consulting your doctor.

Other Medications and Pirazinamida Prodes

Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.

Pirazinamida may affect or be affected by other medications. For example:

  • With some antitubercular medications, such as isoniazid, rifampicin, and ethionamide, liver toxicity may occur, requiring close monitoring of liver function during treatment.
  • With probenecid, an increase in blood uric acid levels and worsening of gout symptoms may occur.
  • When pirazinamida and cyclosporin (an immunosuppressant medication) are used simultaneously, a decrease in cyclosporin blood levels may be observed.
  • When pirazinamida and zidovudine (an HIV treatment medication) are used simultaneously, a decrease in pirazinamida blood levels may be observed.

Pregnancy, Breastfeeding, and Fertility

If you are pregnant, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication. Your doctor will determine if it is possible to continue treatment with this medication during pregnancy.

It is essential to inform your doctor if you are breastfeeding or plan to breastfeed before taking this medication. Your doctor will determine if it is possible to continue treatment with this medication during breastfeeding.

There is no human data available on the long-term effects of pirazinamida on fertility.

Driving and Using Machines

The effects of pirazinamida on the ability to drive and use machines have not been studied. The influence of this product on these functions cannot be predicted.

Pirazinamida Prodes Contains Lactose

This medication contains lactose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medication.

Pirazinamida Prodes Contains Sodium

This medication contains less than 1 mmol of sodium (23 mg) per tablet; it is essentially "sodium-free".

3. How to Take Pirazinamida Prodes

Follow the administration instructions for this medication exactly as indicated by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist again.

The recommended dose depends on the patient's weight and the frequency of administration:

  • Daily administration: the recommended dose ranges from 20 to 30 mg per kg of body weight per day in a single daily dose. The usual dose is 25 mg per kg of body weight per day, but in severe infections, such as meningitis, a higher dose (e.g., 30 mg per kg of body weight per day) may be used.
  • Administration three days a week: the recommended dose ranges from 30 to 40 mg per kg of body weight per day in a single daily dose. The usual dose is 35 mg per kg of body weight per day.

The amount of this medication administered to each person may be different, as it depends on their body weight. Your doctor will indicate your daily dose and treatment duration. Do not stop treatment before completing it. Do not exceed the dose of 2g/day (8 tablets/day).

Use in Children

Children ≥ 3 months

The dose for children is based on their weight. It usually ranges from 30 to 35 mg per kg of body weight per day.

The usual dose for children for the treatment of tuberculosis is 35 mg per kg of body weight per day. In children with weight alterations, a dose reduction may be necessary. In severe infections, such as meningitis, a higher dose (e.g., 40 mg per kg of body weight per day) may be used.

There is insufficient data to establish a recommendation for children under three months.

If You Take More Pirazinamida Prodes Than You Should

If you take more tablets than you should, seek advice from your doctor or pharmacist.If possible, show them the package or this package leaflet.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medication and the amount ingested.

If You Forget to Take Pirazinamida Prodes

If you forget to take a dose, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take the next tablet at the usual time. Do not take a double dose to make up for missed doses.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

The following side effects have been reported with pirazinamida:

Common: may affect up to 1 in 10 patients

  • Allergic reactions.
  • Hyperuricemia (elevated uric acid in the blood). Treatment should be discontinued in case of severe hyperuricemia. The induction of hyperuricemia by pirazinamida is dose-related.
  • Lack of appetite, abdominal pain, nausea, and vomiting.
  • Elevated liver enzymes.
  • Muscle and joint pain. This side effect is dose-dependent and is less frequent and more moderate at the recommended dose.
  • Worsening of porphyria and acute intermittent porphyria (a group of disorders characterized by photosensitivity, skin lesions, anemia, psychosis, and acute abdominal pain).

Rare: may affect up to 1 in 1,000 patients

  • Anemia (sideroblastic), coagulation disorders, changes in platelet count, splenomegaly.
  • Dose-related hepatotoxicity, jaundice (yellowing of the skin due to elevated bilirubin), liver hypertrophy.
  • Skin rash, urticaria, itching, photosensitivity reactions (after sun exposure), acne.
  • Urination disorders, interstitial nephritis (inflammation of the renal tubules).
  • Fever.

It is recommended that, in the case of prolonged treatments, liver function tests be performed periodically.

Reporting Side Effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: https://www.notificaram.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Pirazinamida Prodes

Keep this medication out of the sight and reach of children.

Do not use this medication after the expiration date stated on the package after CAD. The expiration date is the last day of the month indicated.

No special storage conditions are required.

Medications should not be thrown away in drains or trash. Deposit the packages and medications you no longer need in the SIGRE Pointof the pharmacy. If you have any doubts, ask your pharmacist how to dispose of the packages and medications you no longer need. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Pirazinamida Prodes

  • The active ingredient is pirazinamida. Each tablet contains 250 mg of pirazinamida.
  • The excipients are lactose, magnesium stearate, povidone, talvo (E-553b), and sodium croscarmellose.

Appearance of the Product and Package Contents

White, flat, round tablets with a central score line on the lower and upper smooth surface. The score line should not be used to divide the tablet.

Packages of 100 tablets.

Marketing Authorization Holder and Manufacturer

Kern Pharma, S.L.

Venus, 72 - Pol. Ind. Colón II

08228 Terrassa - Barcelona

Spain

Date of the Last Revision of this Package Leaflet:November 2022.

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/.

Online doctors for PYRAZINAMIDE PRODES 250 mg TABLETS

Discuss questions about PYRAZINAMIDE PRODES 250 mg TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (188)
Doctor

Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

0.0 (11)
Doctor

Rita Isabel Calero Garcia

General medicine 2 years exp.

Dr. Rita Isabel Calero Garcia is a physician with extensive experience in emergency medical care, general medicine, and healthcare assistance in various clinical and out-of-hospital settings.

She currently works as a physician at the Canary Islands Emergency Service (Servicio de Urgencias Canario – SUC), where she is responsible for the assessment and care of patients in medical emergency situations, performing the initial diagnosis, patient stabilization, and coordination with hospital services when necessary.

She has also developed her professional activity within the Primary Care Management Service, providing consultations in general medicine. In this setting she is responsible for patient follow-up, management of acute and chronic conditions, as well as health promotion and disease prevention.

She has also worked as a physician in a mobile ICU unit, providing medical assistance in out-of-hospital emergencies, treating critical patients and participating in medicalized patient transport.

In addition, she has collaborated with the Red Cross, participating in healthcare support units, providing medical assistance at events and supporting emergency interventions.

Furthermore, she has provided medical services in the private sector with Salvaser, conducting clinical assessments of patients and providing healthcare services within private medical services.

5.0 (86)
Doctor

Jorge Correa Bellido

General medicine 7 years exp.

Dr. Jorge Correa Bellido is a Spanish physician who offers online consultations in Spanish and English. He graduated from the University of La Laguna and has a solid background in clinical practice and international research.

Throughout his career, he has participated in various medical and academic projects, including a research fellowship in Spain, where he contributed to evidence-based studies in the field of family medicine. This experience allowed him to broaden his global perspective on healthcare and comprehensive patient care.

Dr. Correa Bellido has worked with several healthcare providers in Spain, focusing particularly on patient-centered care and public health initiatives aimed at communities with limited access to healthcare services.

In addition, he actively participates in international medical conferences and workshops, which allows him to stay up to date with the latest medical advances and collaborate with healthcare professionals from different countries.

Dr. Correa Bellido provides comprehensive care for a wide variety of medical conditions, including:

  • respiratory infections
  • gastrointestinal disorders
  • cardiovascular problems
  • endocrine and metabolic diseases
  • musculoskeletal and dermatological conditions
  • as well as mental health conditions such as anxiety and depression.

He also treats infectious and allergic diseases, general health concerns, and provides guidance on prevention and healthy lifestyle habits.

His services include virtual consultations, diagnosis and management of acute and chronic diseases, prescription renewals, and personalized medical advice.

With a patient-centered approach and a strong commitment to continuous learning, Dr. Correa Bellido provides accessible and high-quality healthcare to patients both in Spain and around the world.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

5.0 (100)
Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Doctor

Lizaveta Trafimchuk Takhvaniuk

Dermatology 10 years exp.

Dr. Lizaveta Trafimchuk Takhvaniuk graduated in Medicine and subsequently specialized in Dermatology and Venereology. She has more than 10 years of clinical experience and is licensed to practice in Spain, where she focuses on the comprehensive diagnosis and treatment of dermatological conditions.

Throughout her education and professional career, Dr. Trafimchuk has gained extensive experience in managing diseases of the skin, hair, and nails, as well as in the diagnosis, treatment, and prevention of sexually transmitted infections (STIs). Her clinical approach is based on evidence-based medicine, combined with personalized care tailored to each patient’s needs.

In her daily practice, she treats a wide range of dermatological conditions, including chronic inflammatory dermatoses such as acne, rosacea, atopic dermatitis, psoriasis, and eczema. She also has experience in treating pigmentation disorders, including melasma, post-inflammatory hyperpigmentation, and dyschromia.

She has developed a particular interest in trichology, treating various types of alopecia, chronic hair loss, and scalp disorders. In addition, she has experience in managing infectious dermatoses of fungal, viral, and bacterial origin, as well as in evaluating benign and suspicious skin lesions, with referral to specialized care when necessary.

With a strong interest in a comprehensive approach to skin health, she also treats scars, post-procedural skin changes, and conditions related to hormonal factors and aging, including those associated with pregnancy, menopause, and age-related skin changes.

Thanks to her experience and continuous professional development, Dr. Trafimchuk provides high-quality medical care that is professional, confidential, and aligned with modern dermatology standards.

4.6 (73)
Doctor

Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate

Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Frequently Asked Questions

Is a prescription required for PYRAZINAMIDE PRODES 250 mg TABLETS?

PYRAZINAMIDE PRODES 250 mg TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in PYRAZINAMIDE PRODES 250 mg TABLETS?

The active ingredient in PYRAZINAMIDE PRODES 250 mg TABLETS is pyrazinamide. This information helps identify medicines with the same composition but different brand names.

How much does PYRAZINAMIDE PRODES 250 mg TABLETS cost in pharmacies?

The average pharmacy price for PYRAZINAMIDE PRODES 250 mg TABLETS is around 5.64 EUR. Prices may vary depending on the manufacturer and dosage form.

Who manufactures PYRAZINAMIDE PRODES 250 mg TABLETS?

PYRAZINAMIDE PRODES 250 mg TABLETS is manufactured by Kern Pharma S.L.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of PYRAZINAMIDE PRODES 250 mg TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PYRAZINAMIDE PRODES 250 mg TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy PYRAZINAMIDE PRODES 250 mg TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy PYRAZINAMIDE PRODES 250 mg TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to PYRAZINAMIDE PRODES 250 mg TABLETS?

Other medicines with the same active substance (pyrazinamide) include DELTYBA 50 mg FILM-COATED TABLETS, Myambutol 400 mg film-coated tablets, SIRTURO 100 MG TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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