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PERME-CURE 50 mg/g CREAM

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About the medicine

How to use PERME-CURE 50 mg/g CREAM

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Perme-cure 50 mg/g cream

permethrin

Read the entire package leaflet carefully before starting to use this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor or pharmacist.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Perme-cure and what is it used for
  2. What you need to know before using Perme-cure
  3. How to use Perme-cure
  4. Possible side effects
  5. Storage of Perme-cure
  6. Package Contents and Additional Information

1. What is Perme-cure and what is it used for

Perme-cure contains permethrin as the active ingredient, which belongs to the group of medications called scabicides.

Perme-cure is indicated for the treatment of scabies in adults and children over 2 months of age.

Doctor consultation

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2. What you need to know before using Perme-cure

Do not use Perme-cure

  • if you are allergic to permethrin or any pyrethrin or synthetic pyrethroids, or to any of the other ingredients of this medication (listed in section 6).

Warnings and Precautions

Consult your doctor or pharmacist before starting to use Perme-cure.

Scabies infestation is often accompanied by itching, mild burning, or stinging after application with Perme-cure. Treatment with Perme-cure may temporarily exacerbate these symptoms, although they usually disappear within 2 to 4 weeks. If irritation persists for a longer period, you should consult your doctor.

In case of a hypersensitivity reaction to Perme-cure, its use should be discontinued.

Be careful with this cream if you are prone to asthma attacks, as the use of permethrin may cause difficulty breathing.

If you know you are allergic to chrysanthemums or other plants of the Compositae family, Perme-cure should only be used after consulting your doctor.

Caregivers are recommended to use gloves when applying permethrin.

Avoid contact between Perme-cure and the eyes. If accidental contact occurs, the eyes should be rinsed immediately with plenty of water.

Do not apply to wounds or mucous membranes.

Children up to 23 months of age

Do not use Perme-cure in newborns and infants under 2 months of age, unless your doctor advises you to do so. There is no adequate experience in infants. Treatment for children up to 23 months of age should only be administered under close medical supervision.

Other medications and Perme-cure

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medication.

No interactions with other medications have been reported.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

There is no experience in pregnant women, so Perme-cure should only be used during pregnancy when the doctor recommends it as strictly necessary.

It is not known whether this medication passes into breast milk, so the doctor will decide whether to interrupt breastfeeding or interrupt treatment with Perme-cure, taking into account the benefit of breastfeeding for the child and the benefit of treatment for the mother.

Driving and Using Machines

No effects on the ability to drive or use machines have been reported.

Perme-cure contains castor oil, butylhydroxyanisole, butylhydroxytoluene, ethyl parahydroxybenzoate, propyl parahydroxybenzoate, methyl parahydroxybenzoate, butyl parahydroxybenzoate, and isobutyl parahydroxybenzoate.

This medication may cause skin reactions because it contains castor oil.

This medication may cause local skin reactions (such as contact dermatitis) or eye and mucous membrane irritation because it contains butylhydroxyanisole and butylhydroxytoluene.

It may cause allergic reactions (possibly delayed) because it contains ethyl parahydroxybenzoate, propyl parahydroxybenzoate, methyl parahydroxybenzoate, butyl parahydroxybenzoate, and isobutyl parahydroxybenzoate.

3. How to use Perme-cure

Follow the instructions for administration of this medication exactly as indicated by your doctor or pharmacist. If in doubt, consult your doctor or pharmacist again.

Perme-cure should be used only for external use. Generally, a single application is sufficient to eliminate the infestation.

In any case, your doctor should indicate the duration of treatment with Perme-cure 50mg/g cream.

Apply a sufficient amount of cream to cover the area to be treated.

Before applying the cream, make sure the skin is clean and dry.

.

Apply the cream to the entire body from the base of the neck to the tips of the toes, paying special attention to the areas between the fingers of the hands and feet (including the underside and between the nails), wrists, armpits, genitals, and buttocks (always respecting the genital and anal mucous membranes).

The cream should be in contact with the skin for 8 to 14 hours. After this time, any unabsorbed cream should be removed by washing or showering with warm or cool water.

Reapply the cream to the hands if they are washed before 8 hours to ensure proper treatment.

Generally, a single application is sufficient to eliminate the infection. Only in cases where live mites are observed after 14 days of using the cream will a second application be performed.

It is recommended that you consult your doctor for a review 2 or 4 weeks after treatment.

Avoid contact with the eyes. In case of accidental contact, rinse immediately with plenty of water.

Adults and children over 2 years of age

Should apply the cream to the skin of the entire body, including the palms of the hands and the soles of the feet. Do not apply to the head or face.

Adults over 65 years of age

In addition to considering the same application conditions as for adults and children over 2 years of age, apply to the neck, face, and scalp. Be careful not to apply the cream around the eyes and mouth.

Children between 2 months and 2 years of age

Treatment should be performed under medical supervision.

The use of this medication is not recommended in children under 2 months of age. (See section 2).

Avoid letting children suck the cream from their hands. If necessary, the use of gloves in children is advised.

If you use more Perme-cure than you should

If you have used more Perme-cure than you should, consult your doctor or pharmacist immediately.

In case of accidental ingestion, inform your doctor or pharmacist. Gastric lavage and symptomatic treatment are recommended.

For more information, call the National Toxicology Information Service at 91 562 04 20.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

Very common: may affect more than 1 in 10 people:

  • burning sensation on the skin
  • stinging or itching sensation. This sensation is usually brief and disappears quickly.

Common: may affect up to 1 in 10 people:

  • skin sensation (paresthesia) such as tingling, pinching, burning sensation on the skin, pruritus, erythema, numbness, and skin rash,
  • itching sensation that may persist for 2 to 4 weeks after treatment. This is not common and is caused by an allergic reaction to the remains of dead mites that cause scabies, and it is not a sign that the treatment has failed.

Reporting Side Effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: https://www.notificaram.es.

By reporting side effects, you can contribute to providing more information on the safety of this medication.

5. Storage of Perme-cure

Keep this medication out of sight and reach of children.

This medication does not require special storage conditions.

Do not use this medication after the expiration date shown on the tube and carton after EXP. The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and any unused medication in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medication. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Perme-cure

The active ingredient is permethrin. Each gram of cream contains 50 mg of permethrin.

  • The other ingredients are: Castor Oil, Purified Water, Steareth-2 (polyoxyethylene (2) stearate), butylhydroxyanisole (E-320), citric acid, Ceteareth-2 (C16-18 alcohol, ethoxylated-phosphate), sodium hydroxide (E-524) 20%, Vitamin E acetate, parahydroxybenzoates (2-phenoxyethanol, methyl parahydroxybenzoate (E-218), ethyl parahydroxybenzoate (E-214), butyl parahydroxybenzoate, isobutyl parahydroxybenzoate, propyl parahydroxybenzoate (E-216)), Citric Acid, Disodium EDTA, Butylhydroxytoluene (E-321), and Perfume Timly.

Appearance of the Product and Package Contents

Perme-cure is an oily external phase cream for cutaneous use, presented in polyethylene tubes of 40 and 70 grams.

Marketing Authorization Holder and Manufacturer

Marketing Authorization Holder

Galenicum Derma, S.L.U.

Ctra N-1, Km 36

28750 San Agustin del Guadalix (Madrid) Spain

Manufacturer

Laboratorios ERN, S.A.

Polígono Industrial Can Salvatella

Calle Gorcs i Lladó, 188, Barberà del Vallés

08210 (Barcelona) Spain

or

Ferrer Internacional, S.A.

Joan Buscallá, 1-9

08173 -Sant Cugat del Vallés, Barcelona –Spain

or

Laboratorios Bohm S.A.

C/ Molinaseca, 23-25. Polígono Industrial Cobo Calleja

28947 Fuenlabrada.- Madrid (Spain)

Date of the Last Revision of this Package Leaflet: July 2021

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

  • Country of registration
  • Dosage form
    CREAM, 5 g permethrin / 100 g
  • ATC code
    P03AC04
  • Average pharmacy price
    9.73 EUR
  • Active substance
  • Prescription required
    Yes
  • Manufacturer
  • Alternatives to PERME-CURE 50 mg/g CREAM
    Dosage form:  CREAM, 5 g permethrin / 100 g
    Active substance:  permethrin
    Manufacturer:  Unipharma S.A.
    Prescription required

Online doctors for PERME-CURE 50 mg/g CREAM

Discuss questions about PERME-CURE 50 mg/g CREAM, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (37)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
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  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

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  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
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  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Frequently Asked Questions

Is a prescription required for PERME-CURE 50 mg/g CREAM?
PERME-CURE 50 mg/g CREAM requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PERME-CURE 50 mg/g CREAM?
The active ingredient in PERME-CURE 50 mg/g CREAM is permethrin. This information helps identify medicines with the same composition but different brand names.
How much does PERME-CURE 50 mg/g CREAM cost in pharmacies?
The average pharmacy price for PERME-CURE 50 mg/g CREAM is around 9.73 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures PERME-CURE 50 mg/g CREAM?
PERME-CURE 50 mg/g CREAM is manufactured by Galenicum Derma S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PERME-CURE 50 mg/g CREAM online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PERME-CURE 50 mg/g CREAM is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PERME-CURE 50 mg/g CREAM?
Other medicines with the same active substance (permethrin) include SARCOP 50 MG/G CREAM. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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