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PENILEVEL 500 MG HARD CAPSULES

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About the medicine

How to use PENILEVEL 500 MG HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Penilevel 500 mg Hard Capsules

Phenoxymethylpenicillin Potassium

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Penilevel and what is it used for
  2. What you need to know before you take Penilevel
  3. How to take Penilevel
  4. Possible side effects
  5. Storage of Penilevel
  6. Contents of the pack and other information
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1. What is Penilevel and what is it used for

Penilevel contains phenoxymethylpenicillin as the active substance. Phenoxymethylpenicillin is used to treat certain infections caused by bacteria. It only works on specific strains of bacteria.

Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or the common cold.

It is essential to follow the instructions regarding dosage, administration interval, and treatment duration as indicated by your doctor.

Do not store or reuse this medication. If you have any leftover antibiotic after completing the treatment, return it to the pharmacy for proper disposal. Do not throw away medications down the drain or in the trash.

Penilevel is used to treat the following infections:

Adults

  • Respiratory infections: Acute streptococcal pharyngitis (group A).
  • Acute bacterial infections of the skin and its structures: Scarlet fever, ecthyma, furuncle, impetigo, erysipelas, and erysipeloid.
  • Odontogenic infections: Dental abscesses with disseminated cellulitis.

Adolescents 12 years of age and older

  • Respiratory infections: Acute streptococcal pharyngitis (group A).
  • Bacterial infections of the skin and its structures: Scarlet fever, ecthyma, furuncle, impetigo, erysipelas, and cellulitis.
  • Odontogenic infections: Dental abscesses with disseminated cellulitis.

2. What you need to know before you take Penilevel

Do not take Penilevel

If you are allergic to phenoxymethylpenicillin or any of the other components of this medication (see section 6) or to other beta-lactam antibiotics (penicillins or cephalosporins).

Warnings and precautions

Consult your doctor before starting to take Penilevel, especially if you have previously suffered any hypersensitivity or allergic reaction to any penicillin or other beta-lactam antibiotics.

Penicillins can cause severe allergic reactions that can be fatal.

In the case of patients with impaired renal function, consult your doctor as a dose reduction may be necessary.

Continuous and repeated use of antibiotics should be avoided as it can create resistance and the emergence of other infections.

Patients with renal insufficiency or those on low-potassium diets should note that this medication contains 55 mg (1.4 mmol) of potassium per capsule.

Other medications and Penilevel

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medication.

In particular, inform your doctor or pharmacist about any of the following medications:

  • Methotrexate (medication for treating cancer and psoriasis): Penicillins can increase the risk of toxicity by reducing methotrexate excretion.
  • Oral contraceptives (birth control pills): Penicillins can decrease the effectiveness of oral contraceptives, so additional contraceptive measures may be necessary (e.g., use of male condoms).
  • Probenecid or Sulfinpyrazone (medications for treating gout).

Taking Penilevel with food, drinks, and alcohol

Penilevel can be taken with or without food, although it is preferable to take it on an empty stomach or 1 hour before or 2 hours after meals.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

Driving and using machines

The influence on driving or using machinery is nil or insignificant.

Medicine questions

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3. How to take Penilevel

Your doctor will explain exactly how much Penilevel you should take, how often, and for how long. This will depend on the type of infection you have, its severity, and your weight. Follow your doctor's or pharmacist's instructions for taking this medication exactly. If in doubt, consult your doctor or pharmacist again.

The recommended dose is:

Adults

Indication

Posology

Treatment duration

Acute streptococcal pharyngitis (group A)

500 mg every 12 hours

10 days

Acute bacterial infections of the skin and its structures

Scarlet fever

500 mg every 12 hours

10 days

Ecthyma

125-500 mg every 6 hours

10 days

Furuncle

125-500 mg every 6 hours

10 days

Impetigo

125-500 mg every 6 hours

10 days

Erysipelas

250-500 mg every 6 hours

5 days

Erysipeloid

500 mg every 6 hours

7-10 days

Odontogenic infections

Dental abscesses with disseminated cellulitis

1,000 mg (initial dose)

500 mg (maintenance dose) every 4-6 hours

3-7 days

Adolescents 12 years of age and older

Your doctor will determine the correct dose for your child:

Indication

Posology

Treatment duration

Acute streptococcal pharyngitis (group A)

500 mg every 12 hours

10 days

Acute bacterial infections of the skin and its structures

Scarlet fever

500 mg every 12 hours

10 days

Ecthyma

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

10 days

Furuncle

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

10 days

Impetigo

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

10 days

Erysipelas

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

5 days

Cellulitis

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

5 days

Odontogenic infections

Dental abscesses with disseminated cellulitis

25-50 mg/kg/day (maximum dose: 3 g/day) every 6 hours

5-7 days

Due to the size of the capsules, Penilevel 500 mg hard capsules should not be used in children under 12 years of age or in patients who cannot swallow the capsules whole. For children under 12 years of age, there is a presentation in sachets (Penilevel 250 mg sachets).

Swallow the capsules whole directly with a glass of water. The capsules should not be opened. Penilevel can be taken with or without food, although it is preferable to take it on an empty stomach or 1 hour before or 2 hours after meals.

If you take more Penilevel than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount taken.

If you forget to take Penilevel

If you forget to take a daily dose, take the next dose as usual. Do not take a double dose to make up for forgotten doses.

If you stop taking Penilevel

It is essential to continue taking Penilevel unless your doctor tells you to stop the treatment.

If you have any further questions about the use of this medication, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Penilevel can cause side effects, although not everybody gets them.

The most common side effects are gastrointestinal and allergic reactions.

Stop taking the medication and ask your doctor immediately if you experience any of the following reactions:

  • Allergic reaction accompanied by forced and rapid breathing, flushing, and itching, hives (rash), skin inflammation (especially lips, face, and tongue), chills, or fever,
  • urticaria and skin reactions,
  • tremors,
  • acute and profuse diarrhea, usually accompanied by blood and mucus, stomach pain, and fever.

If the following side effects are common (stomach pain, nausea, vomiting, and diarrhea), discuss them with your doctor or pharmacist.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report them directly through the Spanish Medicines and Healthcare Products Agency's (AEMPS) website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medication.

5. Storage of Penilevel

Keep this medication out of the sight and reach of children.

Store below 25°C. Store in the original packaging to protect it from moisture.

Do not use this medication after the expiration date shown on the box and blister pack after "EXP". The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medication in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medication. This will help protect the environment.

6. Contents of the pack and other information

Composition of Penilevel

  • The active substance is phenoxymethylpenicillin potassium (penicillin V potassium), equivalent to 500 mg of phenoxymethylpenicillin.
  • The other components are: Microcrystalline cellulose, talc, magnesium stearate, gelatin, titanium dioxide (E-171), indigo carmine (E-132), and quinoline yellow (E-104).

Appearance of the product and pack contents

Penilevel 500 mg hard capsules are available in packs of 20, 40, and 500 capsules, in PVDC/PVC-Aluminum blisters of 10 capsules.

Marketing Authorization Holder

LABORATORIOS ERN, S.A.

Perú, 228

08020 Barcelona, Spain.

Manufacturer

LABORATORIOS ERN, S.A.

Gorgs Lladó, 188

08210 Barberá del Vallés, Barcelona, Spain.

Date of the last revision of this leaflet:October 2018

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for PENILEVEL 500 MG HARD CAPSULES

Discuss questions about PENILEVEL 500 MG HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
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  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
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  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
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  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
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  • medication review and treatment adjustment;
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Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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Frequently Asked Questions

Is a prescription required for PENILEVEL 500 MG HARD CAPSULES?
PENILEVEL 500 MG HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in PENILEVEL 500 MG HARD CAPSULES?
The active ingredient in PENILEVEL 500 MG HARD CAPSULES is phenoxymethylpenicillin. This information helps identify medicines with the same composition but different brand names.
How much does PENILEVEL 500 MG HARD CAPSULES cost in pharmacies?
The average pharmacy price for PENILEVEL 500 MG HARD CAPSULES is around 9.65 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures PENILEVEL 500 MG HARD CAPSULES?
PENILEVEL 500 MG HARD CAPSULES is manufactured by Laboratorios Ern S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of PENILEVEL 500 MG HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PENILEVEL 500 MG HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to PENILEVEL 500 MG HARD CAPSULES?
Other medicines with the same active substance (phenoxymethylpenicillin) include BENZETACIL 1,200,000 IU Powder and Solvent for Injectable Suspension, BENZETACIL 2,400,000 IU powder and solvent for injectable suspension, BENZETACIL 600,000 IU Powder and Solvent for Injectable Suspension. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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