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PARACETAMOL 500 mg/65 mg Film-Coated Tablets

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About the medicine

How to use PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS

Contents of the leaflet

  1. Introduction
  2. What Paracetamol/Caffeine Pharmaclan is and what it is used for
  3. What you need to know before you take Paracetamol/Caffeine Pharmaclan
  4. Do not take Paracetamol/Caffeine Pharmaclan
  5. How to take Paracetamol/Caffeine Pharmaclan
  6. Possible side effects
  7. Storage of Paracetamol/Caffeine Pharmaclan
  8. Contents of the pack and other information
  9. C
  10. A

Introduction

Package Leaflet: Information for the User

Paracetamol/Caffeine Pharmaclan 500 mg/65 mg film-coated tablets EFG

paracetamol/caffeine

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What Paracetamol/Caffeine Pharmaclan is and what it is used for
  2. What you need to know before you take Paracetamol/Caffeine Pharmaclan
  3. How to take Paracetamol/Caffeine Pharmaclan
  4. Possible side effects
  5. Storage of Paracetamol/Caffeine Pharmaclan
  6. Contents of the pack and other information

1. What Paracetamol/Caffeine Pharmaclan is and what it is used for

This medicine contains a combination of two active substances, paracetamol and caffeine, and is effective for pain and fever.

Paracetamol relieves pain and reduces fever. Caffeine increases the analgesic effect of paracetamol.

Paracetamol/Caffeine Pharmaclan is indicated for the short-term symptomatic treatment of mild to moderate pain, such as headache, back pain, and toothache.

Paracetamol/Caffeine Pharmaclan also reduces fever.

This medicine is indicated in adults and adolescents ≥12 years (from 40 kg body weight).

You should consult a doctor if the fever persists for more than 3 days or worsens or does not improve, or if the pain persists for more than 5 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Paracetamol/Caffeine Pharmaclan

Do not take Paracetamol/Caffeine Pharmaclan

  • if you are allergic to paracetamol, caffeine, or any of the other ingredients of this medicine (listed in section 6);
  • if you have severe liver failure
  • if you have hepatitis

Warnings and precautionsThis medicine contains paracetamol. Do not take it with other medicines that contain paracetamol, such as medicines for flu and colds. Taking higher doses than recommended can lead to a risk of severe liver damage.

Do not take more than the recommended dose of the medicine. The time interval between individual doses should be at least 4 hours.

Do not drink alcohol during treatment with this medicine.

Consult your doctor or pharmacist before taking Paracetamol/Caffeine Pharmaclan:

  • if you have liver disease;
  • if you regularly drink alcohol;
  • if you have kidney disease;
  • if you have hemolytic anemia (anemia due to the destruction of red blood cells);
  • if you have a deficiency of an enzyme called glucose-6-phosphate dehydrogenase;
  • if you are underweight or malnourished.

Caution is required if:

  • you have a severe infection (sepsis), are underweight, or are malnourished, or have regular problems with alcohol consumption, as this may increase the risk of metabolic acidosis. The symptoms of metabolic acidosis are:
  • difficulty breathing, rapid and deep breathing;
  • nausea (feeling unwell), vomiting;
  • loss of appetite.

If you experience a combination of these symptoms, contact your doctor immediately.

Children and adolescents

This medicine is not indicated in children under 12 years or adolescents with a body weight below 40 kg.

Other medicines and Paracetamol/Caffeine Pharmaclan

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including those obtained without a prescription.

Do not take Paracetamol/Caffeine Pharmaclan in combination with other medicines that contain paracetamol.

The effects of Paracetamol/Caffeine Pharmaclan may interact with the effects of other medicines used at the same time.

Before using Paracetamol/Caffeine Pharmaclan, consult your doctor or pharmacist if you are taking:

? anticoagulant medicines (e.g., warfarin);

? medicines for nausea and vomiting (e.g., metoclopramide, domperidone);

? medicines to lower cholesterol levels in the blood (cholestyramine);

? medicines that contain acetylsalicylic acid or other pain and fever medicines that belong to a class of medicines called non-steroidal anti-inflammatory drugs;

? some antibiotics (rifampicin, chloramphenicol);

? some medicines for the treatment of gout (probenecid);

? some medicines for the treatment of epilepsy (phenobarbital, lamotrigine);

? antiretrovirals for the treatment of HIV (zidovudine);

? medicines for the treatment of tuberculosis (isoniazid);

? lithium for the treatment of some mental illnesses;

? flucloxacillin for the treatment of bacterial infections.

If you are going to have laboratory tests, you should inform your doctor that you are taking this medicine, as it may affect the results of the tests. Paracetamol alters glucose and uric acid concentrations in the blood.

Taking Paracetamol/Caffeine Pharmaclan with food, drink, and alcohol

Alcohol should not be consumed during treatment. Prolonged alcohol consumption significantly increases the risk of liver damage. If you have problems with alcohol consumption, talk to your doctor before starting treatment.

Paracetamol/Caffeine Pharmaclan contains caffeine, so you should avoid excessive consumption of caffeinated beverages while taking this medicine (e.g., tea, coffee, or other caffeinated beverages). High caffeine intake can cause sleep problems, tremors, and chest pain (caused by rapid heartbeats).

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Due to the caffeine content, the use of this medicine is not recommended during pregnancy and breastfeeding.

Caffeine may increase the risk of spontaneous abortion during pregnancy. Caffeine in breast milk may have a stimulating effect on a breastfed baby.

Driving and using machines

Paracetamol/Caffeine Pharmaclan has no influence on the ability to drive or use vehicles and operate machines.

Paracetamol/Caffeine Pharmaclan contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per tablet; i.e., it is almost "sodium-free".

Medicine questions

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Discuss your symptoms and treatment with a doctor online.

3. How to take Paracetamol/Caffeine Pharmaclan

Follow the instructions for administration of this medicine exactly as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

Do not exceed the recommended dose. The time interval between individual doses should be at least 4 hours.

Take the lowest effective dose for the shortest possible time to improve the symptoms of the disease.

Do not take with other medicines that contain paracetamol.

If the pain persists for more than 5 days or if the fever persists for more than 3 days, or the pain or fever worsens or other symptoms appear, you should stop treatment and consult your doctor.

High daily doses of paracetamol should be avoided during prolonged periods, as this increases the risk of adverse effects such as liver damage.

Adults and adolescents from 15 years (from 50 kg body weight)

The recommended dose is 1 tablet per intake. The interval between two doses should be at least 4 hours. A dose of 2 tablets at the same time is recommended only in patients with a body weight above 60 kg if pain relief is not sufficient with 1 tablet or if a higher dose is required due to more intense pain. The maximum daily dose is 6 tablets, which should not be exceeded within a 24-hour period.

Adolescents from 12 to 15 years (from 40 kg body weight)

The recommended dose is 1 tablet per intake, as needed, up to 5 times a day with an interval of at least 4 to 6 hours. The maximum dose per intake is 1 tablet. The maximum daily dose is a total of 5 tablets, which should not be exceeded within a 24-hour period.

Children under 12 years and adolescents with a body weight below 40 kg

The medicine is not indicated in children under 12 years or adolescents with a body weight below 40 kg.

If you have liver or kidney disease, consult your doctor before starting treatment. Your doctor will indicate if you need to reduce the dose or prolong the interval between doses. Do not take this medicine if you have severe liver failure.

Method of administration

For oral use only. Take the tablet with plenty of water.

Paracetamol/Caffeine Pharmaclan can be taken with or without food.

If you take more Paracetamol/Caffeine Pharmaclan than you should

In case of overdose or accidental ingestion by a child, consult your doctor or pharmacist or the nearest medical center immediately and inform them exactly how many tablets you have taken. Show them the used packaging and this leaflet. Paracetamol overdose can cause severe liver damage. In case of overdose or accidental ingestion, you can also call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Paracetamol/Caffeine Pharmaclan

DO NOT take a double dose to make up for forgotten doses. Take the usual dose as soon as you remember. Maintain a minimum interval of 4 hours between doses.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking the medicine and inform your doctor immediately if:

  • you have allergic reactions, such as skin rash or itching, or have breathing problems, problems, or inflammation of the lips, tongue, throat, or face;
  • you have a skin rash with peeling or blisters in the mouth;
  • you have had previous breathing problems after taking acetylsalicylic acid or other pain and fever medicines that belong to a class of medicines called non-steroidal anti-inflammatory drugs, and if you have similar problems after taking this medicine;
  • you have bruising or bleeding of unknown origin.
  • These side effects are rare (affect 1 in 1000 people).

Very rare cases of severe skin reactions (affect 1 in 10,000 people) have been reported.

Other side effects

Rare side effects (may affect 1 in 1000 people)

  • abdominal pain, discomfort (nausea), vomiting, diarrhea;
  • liver problems, liver failure, jaundice;
  • changes in blood counts;
  • sweating, purpura (multiple pinpoint bleeding on the skin);
  • swelling.

Frequency not known (frequency cannot be estimated from the available data):

  • dizziness, headache;
  • insomnia, agitation, anxiety, irritability, nervousness;
  • palpitations (abnormal heartbeats).

These side effects may increase with the combination with caffeinated beverages.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. Even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System for Human Use: https//www.notificaRam.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Paracetamol/Caffeine Pharmaclan

  • Keep this medicine out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the packaging or on the blister after 'EXP'. The expiry date is the last day of the month stated.
  • This medicine does not require any special storage conditions.
  • Do not use this medicine if you notice visible signs of deterioration.
  • Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

C

  • The active substances are: paracetamol 500 mg and caffeine 65 mg in a film-coated tablet.
  • The other ingredients are microcrystalline cellulose, pregelatinized starch (corn), povidone K-30, croscarmellose sodium, stearic acid, magnesium stearate, hypromellose, macrogol 400.

A

Film-coated tablets are oval, white to off-white, scored with 'G55' on one side and smooth on the other side.

The tablets are packaged in blisters (PVC/aluminum) containing 10 or 20 film-coated tablets in a box.

Not all pack sizes may be marketed.

Marketing authorization holder:

Pharmaclan s.r.o.

Trtinová 260/1

Prague 9, 19600

Czech Republic

Manufacturer

Pharmazet Group s.r.o.

Trtinová 260/1, Cakovice

Prague 9, 19600

Czech Republic

This medicine is authorized in the Member States of the European Economic Area under the following names:

Czech Republic

Paracetamol/Caffeine Pharmaclan

Germany

Paracetamol & Caffeine Pharmaclan 500 mg/65 mg film-coated tablets EFG

France

Paracetamol Caffeine Pharmaclan 500 mg/65 mg film-coated tablet

Date of last revision of this leaflet: May 2022

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/

Online doctors for PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS

Discuss questions about PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS Prescription Online

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Frequently Asked Questions

PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS is paracetamol, combinations excl. psycholeptics. This information helps identify medicines with the same composition but different brand names.

PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS is manufactured by Pharmaclan S.R.O.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy PARACETAMOL/CAFFEINE PHARMACLAN 500 MG/65 MG FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (paracetamol, combinations excl. psycholeptics) include ANTICATARRAL EDIGEN ORAL SOLUTION POWDER, ANTIDOL DUAL 500 mg/200 mg FILM-COATED TABLETS, BISOLGRIP FORTE GRANULES FOR ORAL SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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