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Naloxona Accord 0,4 mg/ml injectable solution

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Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe

Contents of the leaflet

  1. Introduction
  2. What is Naloxona Accord and what is it used for
  3. What you need to know before you are given Naloxona Accord
  4. How Naloxona Accord is administered
  5. Possible side effects
  6. Storage of Naloxona Accord
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the Patient

Naloxona Accord 0.4 mg/ml Solution for Injection and Infusion in Pre-filled Syringe

Naloxone Hydrochloride

Read all of this leaflet carefully before this medicine is administered to you because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Naloxona Accord and what is it used for
  2. What you need to know before you are given Naloxona Accord
  3. How Naloxona Accord is administered
  4. Possible side effects
  5. Storage of Naloxona Accord
  6. Contents of the pack and further information

1. What is Naloxona Accord and what is it used for

Naloxone is a medicine used to counteract the effects of opioid overdose, for example, morphine overdose.

Naloxone is used to reverse the unwanted effects of opioids, to counteract central nervous system and respiratory depression (breathing difficulties) that can be life-threatening.

Naloxone is also used to diagnose acute opioid overdose or poisoning.

If a woman has received pain relief medication during childbirth, the newborn may be treated with Naloxona Accord to reverse the unwanted effects of opioids, for example, if the baby has breathing problems or central nervous system depression.

Naloxona Accord should not be used in infants weighing less than 4 kg.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given Naloxona Accord

Naloxona Accord must not be administered:

  • If you are allergic (hypersensitive) to naloxone hydrochloride or any of the other ingredients of this medicine (listed in section 6).

Naloxona Accord should not be used in infants weighing less than 4 kg.

Warnings and PrecautionsConsult your doctor or pharmacist before you are given naloxone. Special caution will be taken:

  • If you have physical dependence on opioids(e.g., morphine), or if you have received high doses of these drugs (you may experience intense withdrawal symptoms after receiving naloxone due to too rapid reversal of the opioid effect; these symptoms can include high blood pressure, palpitations, severe breathing difficulties, or cardiac arrest).
  • If you have any heart or circulatory problems(because it is more likely that side effects such as high or low blood pressure, palpitations, or severe breathing difficulties will occur).

Using Naloxona Accord with other medicines

Tell your doctor or pharmacist that you are using or have recently used or might use any other medicines.

  • If you are taking analgesic medicationsuch as buprenorphine. The analgesic effect may be even more intense while you are being treated with naloxone. However, the reversal of unwanted effects, such as respiratory depression caused by buprenorphine, is limited.
  • If you are taking sedativesas naloxone may have a less rapid effect.
  • If you are taking any medicine that may affect your heart or circulation(e.g., medications for hypertension such as clonidine), including those not prescribed.

Using Naloxona Accord with alcohol

Tell your doctor if you have drunk alcohol. In patients with multiple intoxication (with opioids and sedatives or alcohol), naloxone may have a less rapid effect.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, or think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Pregnancy

There is limited information on the use of naloxone in pregnant women. During pregnancy, your doctor will weigh the benefits of naloxone against the possible risks to the embryo or fetus. Naloxone may cause withdrawal symptoms in the newborn.

Breastfeeding

It is not known whether naloxone passes into breast milk or whether the baby is affected by Naloxona Accord. Therefore, breastfeeding should be avoided for 24 hours after treatment.

Driving and Using Machines

After receiving naloxone to reverse the effects of opioids, you should not drive, use machinery, or perform any other activity that requires physical or mental effort for at least 24 hours, as the effects of the opioids may recur.

Naloxona Accord contains sodium

This medicine contains less than 23 mg of sodium (1 mmol) per dose; it is essentially "sodium-free".

3. How Naloxona Accord is administered

The recommended doses are:

To reverse the unwanted effects of opioids:

Adults: 0.1 to 0.2 mg, if necessary, additional injections of 0.1 mg may be administered.Children: 0.01 to 0.02 mg per kg body weight, if necessary, additional injections of the same dose may be administered.

Diagnosis of opioid overdose or poisoning:

Adults: 0.4 mg to 2 mg, if necessary, injections may be repeated at intervals of 2 to 3 minutes. The maximum dose should not exceed 10 mg.

Children: 0.01 mg per kg body weight, if necessary, an additional injection of 0.1 mg per kg may be administered.

Reversal of unwanted effects of opioids in newborns whose mothers have received opioids:

0.01 mg per kg body weight; if necessary, additional injections may be administered.

To reverse the unwanted effects of opioids (in adults, children, and also in newborns), patients are monitored to check that the desired effect of naloxone occurs. If necessary, additional doses may be administered every one to two hours.

In elderly patients with heart or circulatory problems or in those receiving medications that may cause circulatory or heart disorders (e.g., cocaine, methamphetamine, tricyclic antidepressants, calcium channel blockers, beta-blockers, digoxin), naloxone will be used with caution as serious side effects such as rapid heart rate (ventricular tachycardia) and fibrillation have occurred.

Naloxona Accord should not be used in infants weighing less than 4 kg.

If you feel that the effect of Naloxona Accord is too strong or too weak, tell your doctor.

Method of administration

Naloxone will always be administered by intravenous or intramuscular injection or, after dilution, as intravenous infusion (over a long period). Naloxona Accord will be administered by your anesthesiologist or by a doctor with experience.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, naloxone can cause side effects, although not everybody gets them.

It may be difficult to know which side effects are caused by Naloxona Accord, as it is always administered after other medicines have been used.

The following side effects may be serious. If you experience any of the following, tell a doctor immediately:

Common: may affect up to 1 in 10 people

  • Rapid heart rate

Uncommon: may affect up to 1 in 100 people

  • Changes in the way your heart beats, slow heart rate

Rare: may affect up to 1 in 1,000 people

  • Seizures

Very rare: may affect up to 1 in 10,000 people

  • Allergic reactions (hives, nasal congestion or cold, difficulty breathing, angioedema, anaphylactic shock
  • Fibrillation, cardiac arrest
  • Fluid in the lungs (pulmonary edema)

Other side effects include:

Very common: may affect more than 1 in 10 people

  • Nausea

Common: may affect up to 1 in 10 people

  • Dizziness, headache
  • Increased or decreased blood pressure (you may have a headache or feel dizzy)
  • Vomiting
  • If a very high dose is administered after an operation, you may feel excited and have pain (because the analgesic effects of the medicines you have received will be counteracted, as well as the effects on your breathing)

Uncommon: may affect up to 1 in 100 people

  • Involuntary tremors, sweating
  • Diarrhea, dry mouth
  • Excessive breathing (hyperventilation)
  • Irritation of blood vessel walls (after intravenous administration); local irritation and inflammation (after intramuscular administration)

Rare: may affect up to 1 in 1,000 people

  • Tension

Very rare: may affect up to 1 in 10,000 people

  • Discoloration and skin lesions (erythema multiforme)

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Agency's website: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Naloxona Accord

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton or label of the syringe after "EXP". The expiry date refers to the last day of the month shown.

No special storage conditions are required.

Keep the syringe in the original packaging to protect it from light.

Shelf life after first opening of the package

After first opening of the package, the medicine should be used immediately

Shelf life after dilution

Chemical and physical stability have been demonstrated for 36 hours at 2-8°C and 25°C.

From a microbiological point of view, the dilutions should be used immediately. If not used immediately, the in-use storage times and conditions are the responsibility of the user and would normally not be longer than 24 hours at 2-8°C, unless the dilution has been made in a controlled and validated aseptic environment.

Do not use this medicine if you notice a change in the color of the solution or visible signs of deterioration.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Naloxona Accord

The active substance is naloxone hydrochloride. Each pre-filled syringe with 1 ml contains 0.4 mg of naloxone hydrochloride (as dihydrate).

The other ingredients are sodium chloride, hydrochloric acid (for pH adjustment), and water for injections.

Appearance and packaging of the product

Naloxona Accord is a clear and colorless solution for injection/infusion in a pre-filled syringe, practically free from foreign particles.

1 ml glass syringe with a tip cap, plunger stopper (gray bromobutyl rubber), and plunger rod (polypropylene). Graduations for 0.1 ml are present on the syringe cylinder.

The pre-filled syringe is provided with a needle (23 G; 30 mm), packaged in a Twist Box.

Package size: one pre-filled syringe and one needle.

Marketing authorization holder and manufacturerMarketing authorization holderAccord Healthcare S.L.U.

World Trade Center

Moll de Barcelona, s/n

Edifici Est 6ª planta,

08039 Barcelona,

Spain

ManufacturerAccord Healthcare Polska Sp.z o.o.

ul. Lutomierska 50,

95-200 Pabianice

Poland

Or

Laboratori Fundació Dau

C/ C, 12-14 Pol. Ind.

Zona Franca, Barcelona, 08040

Spain

Date of last revision of this leaflet: December 2022

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.es

Online doctors for NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe

Discuss questions about NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64

Frequently Asked Questions

NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe is naloxone. This information helps identify medicines with the same composition but different brand names.

NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe is manufactured by Accord Healthcare S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

The prescription is issued by a doctor after assessing your health. In Spain, NALOXONE ACCORD 0.4 mg/mL injectable solution in pre-filled syringe is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.

To request a review, you can use Oladoctor:

Other medicines with the same active substance (naloxone) include FOMED 0.4 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, NALOXONE B. BRAUN 0.4 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, NYXOID 1.8 mg NASAL SPRAY SOLUTION SINGLE-DOSE CONTAINER. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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