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MONOPROST 50 micrograms/ml eye drops solution in single-dose containers

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About the medicine

How to use MONOPROST 50 micrograms/ml eye drops solution in single-dose containers

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Monoprost 50 micrograms/ml eye drops, solution in single-dose container

Latanoprost

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again. If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet

  1. What is Monoprost and what is it used for
  2. What you need to know before you use Monoprost
  3. How to use Monoprost
  4. Possible side effects
  5. Storage of Monoprost
  6. Contents of the pack and other information

1. What is Monoprost and what is it used for

Monoprost belongs to a group of medicines known as prostaglandins. It works by increasing the natural flow of fluid from inside the eye into the bloodstream.

Monoprost is used to treat conditions known as open-angle glaucoma and ocular hypertensionin adults. Both conditions are related to an increase in pressure inside the eye, which can affect vision.

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Monoprost

Do not use Monoprost

  • If you are allergic (hypersensitive) to latanoprost or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor, pharmacist, or nurse before you start using Monoprost if you think any of the following apply to you:

  • If you have had or are going to have eye surgery (including cataract surgery).
  • If you have eye problems (such as eye pain, irritation, or inflammation, blurred vision).
  • If you have severe asthma or uncontrolled asthma.
  • If you use contact lenses. You can continue to use Monoprost, but you must follow the instructions in section 3 for contact lens users.
  • If you have had or are having a viral infection of the eye caused by the herpes simplex virus (HSV).

Children

Monoprost has not been investigated in children (under 18 years).

Using Monoprost with other medicines

Monoprost may interact with other medicines. Tell your doctor or pharmacist what you are using, have recently used, or might use.

Pregnancy and breastfeeding

Do not use Monoprostif you are pregnant or breastfeeding.

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

When using Monoprost, blurred vision may occur for a short time. If this happens, do not driveor use tools or machines until your vision is clear again.

Important information about some of the ingredients of Monoprost

Monoprost containsmacrogolglycerol hydroxystearate (derived from castor oil), which may cause allergic reactions.

3. How to use Monoprost

Usual dose

  • Follow your doctor's instructions for using Monoprost exactly. If you are unsure, consult your doctor or pharmacist again.
  • The usual dose for adults (including the elderly) is one drop in the affected eye(s) once a day. It is best to administer it at night.
  • Do not use Monoprost more than once a day, as the effectiveness of the treatment may decrease if it is administered more frequently.
  • Follow the administration instructions for the medicine contained in this package leaflet or as indicated by your doctor. If you are unsure, ask your doctor, pharmacist, or nurse.

Contact lens users

If you use contact lenses, you must remove them before using Monoprost. After applying Monoprost, wait 15 minutes before putting your contact lenses back in.

Instructions for use

The eye drops are supplied in single-dose containers. The solution from one single-dose container of Monoprost should be used immediately after opening to treat the affected eye(s). Since sterility cannot be guaranteed after opening each single-dose container, a new container must be opened before each use, which must be discarded immediately after administration.

To use the eye drops, follow these instructions:

  1. Wash your hands and sit or stand comfortably.
  2. Open the pouch containing the single-dose containers. Note the date of first opening on the pouch.
  3. Separate one single-dose container from the strip.

Hand holding four vials of medication with an arrow indicating the point of grip and preparation

  1. Twist the tip of the single-dose container as shown. Do not touch the tip after opening the container.

Vial of medication with cap turning in the direction of the clock hands, curved arrow indicating rotation

  1. Gently separate the lower eyelid of the affected eye with your finger.
  2. Place the tip of the single-dose container close to the eye, without touching it.
  3. Gently press the single-dose container so that only one drop falls into the eye, then remove your finger from the lower eyelid.

Hand applying a drop to the eye with the patient looking up and lower eyelid stretched

  1. Press the tip of the affected eye with your finger, near the nose. Apply pressure for 1 minute, keeping your eye closed.

Index finger gently pulling the lower eyelid down to expose the conjunctiva

  1. Repeat the operation in the other eye, if your doctor has indicated it. Each single-dose container contains enough for both eyes.
  2. After use, discard the single-dose container. Do not save it for later use. Since sterility cannot be guaranteed after opening the single-dose container, a new container must be opened before each use.

If you use Monoprost with other eye drops

Wait at least 5 minutes between applying Monoprost and administering other eye drops.

If you use more Monoprost than you should

If you have applied more drops in the eye than you should, you may feel mild irritation in the eye, and your eyes may become red and tear; this situation should disappear, but if it concerns you, contact your doctor.

If you accidentally ingest Monoprost, consult your doctor as soon as possible.

If you forget to use Monoprost

Continue with the administration of the next dose as usual. Do not apply an extra drop in the eye to make up for the missed dose. If you are unsure, consult your doctor or pharmacist.

If you stop using Monoprost

If you want to stop using Monoprost, you must consult your doctor.

If you have any other questions about using this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following adverse reactions are known with the use of Monoprost:

Very common: may affect more than 1 in 10 patients.

  • Gradual change in eye color due to an increase in the amount of brown pigment in the colored part of the eye, known as the iris.
    • If you have mixed-color eyes (blue-brown, gray-brown, yellow-brown, or green-brown), you are more likely to notice this change than if your eyes are a single color (blue, gray, green, or brown).
    • The change in eye color may take years to develop, although it can usually be seen after 8 months of treatment.
    • The change in eye color may be permanent and may be more noticeable if Monoprost is used in only one eye.
    • The change in eye color does not seem to be associated with the development of any problems.
    • The change in eye color does not progress once treatment with Monoprost has been stopped.
  • Redness of the eye.
  • Ocular irritation (feeling of stinging, feeling of grit in the eye, itching, pain, and feeling of a foreign body in the eye).
  • Gradual change in the eyelashes of the treated eye and the fine hair around the treated eye, observed in most patients of Japanese origin. These changes include an increase in color (darkening), length, thickness, and number of eyelashes.

Common: may affect up to 1 in 10 patients

  • Irritation or erosion of the surface of the eye, inflammation of the eyelid (blepharitis), and eye pain, and sensitivity to light (photophobia), conjunctivitis.

Uncommon: may affect up to 1 in 100 patients

  • Swelling of the eyelids, dry eye, inflammation or irritation of the surface of the eye (keratitis), blurred vision, inflammation of the colored part of the eye (uveitis), swelling of the retina (macular edema).
  • Skin rash.
  • Chest pain (angina), feeling the heartbeat (palpitations).
  • Asthma, difficulty breathing (dyspnea).
  • Chest pain.
  • Headache, dizziness.
  • Muscle pain, joint pain.
  • Nausea, vomiting.

Rare: may affect up to 1 in 1,000 patients

  • Inflammation of the iris (iritis), symptoms of swelling or injury/damage to the surface of the eye, swelling around the eye (periorbital edema), misdirected eyelashes or additional row of eyelashes, accumulation of fluid in the colored part of the eye (iris cyst).
  • Reactions on the skin of the eyelids, darkening of the skin of the eyelids.
  • Worsening of asthma.
  • Intense itching of the skin.
  • Development of a viral infection of the eye caused by the herpes simplex virus (HSV).

Very rare: may affect up to 1 in 10,000 patients

  • Worsening of angina in patients who also have heart problems.
  • Appearance of sinking of the eye (deepening of the eye sulcus).

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https//: notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Monoprost

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the packaging, on the outer packaging, and on the single-dose container. The expiry date is the last day of the month stated.

Store below 25°C.

After first opening the pouch: use the single-dose containers within the next 10 days.

After first opening the single-dose container: use immediately and discard the single-dose container after use.

Medicines should not be disposed of via wastewater or household waste. Place the containers and medicines you no longer need in the SIGRE collection point at the pharmacy. If you are unsure, ask your pharmacist how to dispose of the containers and medicines you no longer need. This will help protect the environment.

6. Contents of the pack and other information

Composition of Monoprost

The active substance is latanoprost.

1 ml of eye drops contains 50 micrograms of latanoprost.

The other ingredients (excipients) are: macrogolglycerol hydroxystearate 40, sorbitol, carbomer 974P, macrogol 4000, disodium edetate, sodium hydroxide (for pH adjustment), water for injections.

Appearance of the product and pack contents

This medicine is presented as eye drops, solution, in single-dose containers. The solution is slightly yellow and opalescent, without preservatives, contained in single-dose containers, presented in a pouch with 5 or 10 units. Each single-dose container contains 0.2 ml of eye drops solution.

The boxes contain 5 (1 x 5), 10 (2 x 5), 10 (1 x 10), 30 (6 x 5), 30 (3 x 10), 90 (18 x 5), or 90 (9 x 10) single-dose containers.

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

LABORATOIRES THEA

12 RUE LOUIS BLERIOT

63017 CLERMONT-FERRAND CEDEX 2

FRANCE

Manufacturer

EXCELVISION

27, rue de la Lombardière

ZI la Lombardière

07100 ANNONAY

FRANCE

Or

LABORATOIRES THEA

12 RUE LOUIS BLERIOT

63017 CLERMONT-FERRAND CEDEX 2

FRANCE

Or

LABORATOIRE UNITHER

1 rue de l’Arquerie 50200 Coutances

FRANCE

Or

FAREVA Mirabel

Route de Marsat

Riom

63693 Clermont-Ferrand Cedex 9

FRANCE

Local representative

LABORATORIOS THEA, S.A.

C/ Enric Granados, nº 86-88, 2ª planta

08008 – Barcelona

This medicine is authorized in the Member States of the European Economic Area under the following names

Germany, Belgium, Bulgaria, Cyprus, Denmark, Spain, Finland, France, Greece, Netherlands, Iceland, Italy, Latvia, Luxembourg, Norway, Poland, Portugal, Sweden

Monoprost

Ireland Monopost Unidose

Austria, Slovenia, Lithuania, Czech Republic, Slovakia, United Kingdom, Romania

Monopost

Estonia…………………………………………………………………………………Monopro

Date of last revision of this package leaflet: May 2025

Online doctors for MONOPROST 50 micrograms/ml eye drops solution in single-dose containers

Discuss questions about MONOPROST 50 micrograms/ml eye drops solution in single-dose containers, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Andrei Popov

General medicine 7 years exp.

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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€80
5.0 (184)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50
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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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€55
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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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€60

Frequently Asked Questions

Is a prescription required for MONOPROST 50 micrograms/ml eye drops solution in single-dose containers?
MONOPROST 50 micrograms/ml eye drops solution in single-dose containers requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MONOPROST 50 micrograms/ml eye drops solution in single-dose containers?
The active ingredient in MONOPROST 50 micrograms/ml eye drops solution in single-dose containers is latanoprost. This information helps identify medicines with the same composition but different brand names.
How much does MONOPROST 50 micrograms/ml eye drops solution in single-dose containers cost in pharmacies?
The average pharmacy price for MONOPROST 50 micrograms/ml eye drops solution in single-dose containers is around 15.61 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures MONOPROST 50 micrograms/ml eye drops solution in single-dose containers?
MONOPROST 50 micrograms/ml eye drops solution in single-dose containers is manufactured by Laboratoires Thea. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MONOPROST 50 micrograms/ml eye drops solution in single-dose containers online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MONOPROST 50 micrograms/ml eye drops solution in single-dose containers is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MONOPROST 50 micrograms/ml eye drops solution in single-dose containers?
Other medicines with the same active substance (latanoprost) include CATIOLANZE 50 micrograms/ml EMULSION EYE DROPS, LATANEST 50 micrograms/ml eye drops solution, LATANOPROST AUROVITAS 50 micrograms/ml EYE DROPS SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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