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MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION

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About the medicine

How to use MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Meropenem Qilu 1 g Powder for Solution for Injection and Infusion EFG

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again. If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Meropenem Qilu and what is it used for
  2. What you need to know before you use Meropenem Qilu
  3. How to use Meropenem Qilu
  4. Possible side effects
  5. Storage of Meropenem Qilu
  6. Contents of the pack and other information

1. What is Meropenem Qilu and what is it used for

Meropenem Qilu contains the active substance meropenem and belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria that can cause serious infections.

Informative text about the correct use of antibiotics and the importance of following medical instructions

Meropenem Qilu is used to treat the following infections in adults and children from 3 months of age:

  • Infection affecting the lungs (pneumonia)
  • Bronchial and lung infections in patients with cystic fibrosis (a hereditary disease in which the lungs and digestive system can become clogged with thick, sticky mucus)
  • Complicated urinary tract infections
  • Complicated infections in the abdomen (stomach)
  • Infections that you can acquire during and after childbirth
  • Complicated skin and soft tissue infections
  • Acute bacterial infection of the brain (meningitis)

This medicine can be used to treat patients with weakened immune systems (neutropenic patients) who have a fever that is suspected to be due to a bacterial infection.

Meropenem Qilu can be used to treat bacterial infection of the blood that may be associated with one of the aforementioned types of infection.

Doctor consultation

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2. What you need to know before you use Meropenem Qilu

Do not use Meropenem Qilu

  • if you are allergic to meropenem or any of the other ingredients of this medicine (listed in section 6).
  • if you are allergic to other antibiotics such as penicillins, cephalosporins, or carbapenems, as you may also be allergic to meropenem.

Warnings and precautions

Talk to your doctor or pharmacist before starting Meropenem Qilu

  • if you have health problems, such as liver or kidney problems.
  • if you have had severe diarrhea after taking other antibiotics.

Blood tests

You may develop a positive response to a test (Coombs test) that indicates the presence of antibodies that can destroy red blood cells.

Your doctor will discuss this with you.

Skin reactions

You may develop signs and symptoms of severe skin reactions (see section 4). If this happens, inform your doctor or nurse immediately so that they can treat the symptoms.

If you are in any of these situations, or if you have doubts, consult your doctor before using this medicine.

Other medicines and Meropenem Qilu

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. This is because Meropenem Qilu may affect the way some medicines work, and some of these may affect Meropenem Qilu.

In particular, tell your doctor or nurse if you are taking any of the following medicines:

  • Probenecid (used to treat gout).
  • Valproic acid/sodium valproate/valpromide (used to treat epilepsy). Meropenem Qilu should not be used, as it may decrease the effect of sodium valproate.
  • Oral anticoagulant agent (used to treat or prevent blood clots).

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

It is preferable to avoid the use of meropenem during pregnancy.

Your doctor will decide whether you should use Meropenem Qilu.

It is important that you inform your doctor if you are breastfeeding or plan to breastfeed before receiving Meropenem Qilu. Small amounts of this medicine pass into breast milk. Therefore, your doctor will decide whether you should use meropenem during breastfeeding.

Driving and using machines

No studies have been conducted on the effects on the ability to drive and use machines.

However, meropenem has been associated with headache and tingling or numbness in the skin (paresthesia). Either of these effects could affect your ability to drive or use machines.

This medicine may cause involuntary muscle movements, leading to rapid and uncontrolled body movements (convulsions), which are usually accompanied by loss of consciousness. Do not drive or use machines if you experience this side effect.

Meropenem Qilu contains sodium

This medicine contains 90 mg of sodium (a major component of cooking/table salt) per 1 g dose. This is equivalent to 4.5% of the maximum recommended daily intake of sodium for an adult.

If you have a condition that requires you to control your sodium intake, inform your doctor, pharmacist, or nurse.

3. How to use Meropenem Qilu

Follow exactly the instructions for administration of this medicine given by your doctor or pharmacist. In case of doubt, ask your doctor, pharmacist, or nurse.

Use in adults

  • The dose depends on the type of infection you have, the area of the body affected, and its severity. Your doctor will decide what dose you need.
  • The normal dose in adults is between 500 mg and 2 g. You will usually be given a dose every 8 hours. However, if your kidneys do not work well, you may receive the dose less frequently.

Use in children and adolescents

The dose for children over 3 months and up to 12 years is decided using the child's age and weight. The normal dose is between 10 mg and 40 mg of meropenem per kilogram (kg) of the child's weight. You will usually be given a dose every 8 hours. Children who weigh more than 50 kg will be given an adult dose.

How to use Meropenem Qilu

  • Meropenem Qilu will be given to you as an injection or infusion into a large vein.
  • Meropenem Qilu will usually be given to you by your doctor or nurse.
  • However, some patients, parents, or caregivers are trained to administer Meropenem Qilu at home. The instructions for this are found in this leaflet (in the section called "Instructions for administering Meropenem Qilu to yourself or another person at home"). Follow exactly the instructions for administration of Meropenem Qilu given by your doctor. If you have doubts, ask your doctor.
  • Your injection should not be mixed with or added to solutions that contain other medicines.
  • The injection may take approximately 5 minutes or between 15 and 30 minutes. Your doctor will tell you how Meropenem Qilu is administered.
  • The injections should usually be given at the same time every day.

If you use more Meropenem Qilu than you should

If you accidentally use more than the prescribed dose, contact your doctor or go to the nearest hospital immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to use Meropenem Qilu

If you miss a dose, you should receive it as soon as possible. However, if it is almost time for your next dose, do not receive the missed dose. Do not use a double dose (two injections at the same time) to make up for a missed dose.

If you stop using Meropenem Qilu

Do not stop using Meropenem Qilu until your doctor tells you to.

If you have any further questions on the use of this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Severe allergic reactions

If you experience any of these symptoms, inform your doctor or nurse immediately. You may need urgent medical treatment. The symptoms can include a sudden onset of:

  • Severe rash, itching, or hives on the skin.
  • Swelling of the face, lips, tongue, or other parts of the body.
  • Shortness of breath, wheezing, or difficulty breathing.
  • Severe skin reactions that include:
  • Severe hypersensitivity reactions with fever, skin rash, and changes in blood test results that check liver function (increased levels of liver enzymes), increased levels of a type of white blood cell (eosinophilia), and swelling of the lymph nodes. These can be signs of a multi-organ sensitivity disorder known as DRESS syndrome.
  • Severe scaly red rash, skin bumps containing pus, blisters, or skin peeling, which can be associated with high fever and joint pain.
  • Severe skin reactions that can appear as circular red patches, often with central blisters, on the trunk, skin peeling, ulcers in the mouth, throat, nose, genitals, and eyes, and which can be preceded by fever and flu-like symptoms (Stevens-Johnson syndrome) or a more severe form (toxic epidermal necrolysis).

Damaged red blood cells

The symptoms include:

  • Shortness of breath when you do not expect it
  • Red or brown urine

If you notice any of the above, go to a doctor immediately.

Possible side effects

Common (may affect up to 1 in 10 people)

  • Abdominal pain (stomach pain).
  • Feeling sick (nausea).
  • Vomiting.
  • Diarrhea.
  • Headache.
  • Skin rash, itching.
  • Pain and inflammation (swelling at the injection site).
  • Increased platelet count in the blood (checked in a blood test).
  • Changes in blood tests, including tests that show how your liver is working.

Uncommon (may affect up to 1 in 100 people)

  • Changes in the blood. These include a decrease in the number of platelets (which can make you bruise more easily), an increase in some white blood cells, a decrease in other white blood cells, and an increase in the amount of a substance called "bilirubin". Your doctor may perform blood tests periodically.
  • Changes in blood tests, including tests that show how your kidneys are working.
  • Feeling of tingling (pins and needles).
  • Mouth or vaginal infections caused by a fungus.
  • Inflammation of the intestine with diarrhea.
  • Pain in the veins where Meropenem Qilu is injected.
  • Other changes in your blood. The symptoms include frequent infections, fever, and sore throat. Your doctor may perform blood tests periodically.

Rare (may affect up to 1 in 1,000 people)

  • Seizures (fits).
  • Sudden confusion and disorientation (delirium).

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Agency's website: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Meropenem Qilu

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and vial label after EXP. The expiry date refers to the last day of the month shown.

This medicine does not require any special storage conditions.

After reconstitution/dilution:

Administration of intravenous bolus injection

An injection solution is prepared by dissolving the medicine in water for injection, to a final concentration of 50 mg/ml.

The reconstituted solution of the medicinal product in water for injection must be used immediately.

Administration by intravenous infusion

An infusion solution is prepared by dissolving the medicine in a 9 mg/ml sodium chloride (0.9%) infusion solution or in a 50 mg/ml dextrose (5%) infusion solution, to a final concentration of 1 to 20 mg/ml.

The reconstituted solution of the medicinal product in 9 mg/ml sodium chloride (0.9%) infusion solution must be used immediately. The maximum time that should elapse between the start of reconstitution and the end of infusion should not exceed one hour.

The reconstituted solution of the medicinal product in 50 mg/ml dextrose (5%) infusion solution must be used immediately.

Do not freeze the reconstituted solution.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and other information

Composition of Meropenem Qilu

The active substance is meropenem.

Each vial contains 1 g of meropenem (as meropenem trihydrate).

The other ingredient is sodium carbonate.

Appearance of Meropenem Qilu and pack contents

Meropenem Qilu is presented in vials containing a white or slightly yellow powder for solution for injection or infusion.

Pack sizes of 1 or 10 vials (clinical pack).

Not all pack sizes may be marketed.

Marketing authorization holder and manufacturer

Marketing authorization holder

QILU PHARMA SPAIN S.L.

Paseo de la Castellana 40, 8th floor,

28046 Madrid,

Spain

Manufacturer

KYMOS, S.L.

Ronda de Can Fatjó,

7B (Parque Tecnológico del Vallès),

Cerdanyola del Vallès,

08290 Barcelona,

Spain

Eurofins Analytical Services Hungary Kft.

Anonymus utca 6, Budapest

H-1045,

Hungary

LLC “UNIFARMA”

Vangazu street 23,

Riga, LV-1024,

Latvia

Local representative:

Sun Pharma Laboratorios, S.L.

Rambla de Catalunya, 53-55

08007 – Barcelona

Spain

Tel.: +34 93 342 7890

This medicine is authorized in the Member States of the European Economic Area under the following names:

Member State

Medicine name

Germany

Meropenem Qilu 1 g Powder for solution for injection/infusion

Bulgaria

Meropenem Qilu 1 g ????? ?? ???????????/?????????? ???????

Croatia

Meropenem Qilu 1000 mg powder for solution for injection/infusion

Denmark

Meropenem Qilu

Estonia

Meropenem Qilu

Finland

Meropenem Qilu 1 g injektio-/infuusiokuiva-aine liuosta varten

France

MEROPENEM QILU 1g, powder for solution for injection/infusion

Hungary

Meropenem Qilu 1 g por oldatos injekcióhoz/infúzióhoz

Italy

Meropenem Qilu

Lithuania

Meropenem Qilu 1 g milteliai injekciniam ar infuziniam tirpalui

Latvia

Meropenem Qilu 1 g pulveris injekciju/infuziju škiduma pagatavošanai

Norway

Meropenem Qilu

Spain

Meropenem Qilu 1 g polvo para solución inyectable y para perfusión EFG

Sweden

Meropenem Qilu 1 g pulver till injektions-/infusionsvätska, lösning

Slovenia

Meropenem Qilu 1000 mg prašek za raztopino za injiciranje/infundiranje

Date of last revision of this leaflet: 12/2023

Other sources of information:

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION

Discuss questions about MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
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  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
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Additional care areas:

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  • Medical advice and follow-up consultations.
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  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
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  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
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  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
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  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Frequently Asked Questions

Is a prescription required for MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION?
MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION?
The active ingredient in MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION is meropenem. This information helps identify medicines with the same composition but different brand names.
Who manufactures MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION?
MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION is manufactured by Qilu Pharma Spain S.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MEROPENEM QILU 1g POWDER FOR INJECTION AND INFUSION SOLUTION?
Other medicines with the same active substance (meropenem) include ARCHIFAR 1G POWDER FOR INJECTABLE SOLUTION AND FOR INFUSION, ARCHIFAR 500 mg POWDER FOR INJECTABLE SOLUTION AND FOR INFUSION, MEROPENEM ACCORDPHARMA 1 g POWDER FOR INJECTION AND INFUSION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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