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MELGAMA 300 MG FILM-COATED TABLETS

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About the medicine

How to use MELGAMA 300 MG FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET

Package Leaflet: Information for the Patient

Melgama 300mg film-coated tablets

benfotiamine

Read this package leaflet carefully before you start taking this medicine, as it contains important information for you.

Follow the instructions for administration of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve.

Contents of the package leaflet

  1. What is Melgama and what is it used for
  2. What you need to know before taking Melgama
  3. How to take Melgama
  4. Possible side effects
  5. Storage of Melgama
  6. Package contents and additional information

1. What is Melgama and what is it used for

Melgama contains benfotiamine, which is a derivative of vitamin B1 that, after ingestion, is converted into vitamin B1.

Most people get enough vitamin B1 from their diet, but you may not absorb enough vitamin B1 if you have had stomach surgery, are on hemodialysis, have certain intestinal diseases, follow a restrictive diet, have diabetes or alcoholism, or are elderly.

Benfotiamine is used in adults in the following situations:

Treatment and prevention of vitamin B1 deficiency, if it cannot be controlled with an adequate diet.

This medicine is indicated for use in adults.

The tablets can be taken as long as symptoms persist or a dietary supplement is required; follow the recommendations of your doctor or pharmacist.

You should consult a doctor if it worsens or does not improve.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Melgama

Do not take Melgama

If you are allergic to benfotiamine, thiamine, or any of the other components of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to take Melgama.

Children and adolescents

This medicine must not be used in children and adolescents under 18 years of age, as the safety and benefits of this medicine in people under 18 years of age are not yet known.

Other medicines and Melgama

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicine.

5-fluorouracil, which is a chemotherapy medicine used to treat cancer, may reduce the action of vitamin B1.

Taking Melgama with food and drinks

There are no data on the influence of food on this medicine.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Do not use this medicine unless it is prescribed by a doctor. Your doctor will only prescribe this medicine after carefully considering the risks and benefits. Your doctor will also consider other forms of vitamin B1 supplementation you may be taking (such as multivitamins before conception and during pregnancy).

The influence of benfotiamine on fertility is unknown.

Driving and using machines

Melgama has no significant influence on the ability to drive and use machines.

Melgama contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per film-coated tablet; it is essentially "sodium-free".

3. How to take Melgama

Follow the instructions for administration of the medicine contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

Use in adults

Prevention:usually, half a tablet or one whole film-coated tablet (150-300 mg) once a day.

Treatment:1 film-coated tablet (300 mg) once a day.

Use in children and adolescents

This medicine is not suitable for use in children and adolescents under 18 years of age.

Elderly patients

The same dose as for adults is applied.

Renal impairment

In patients with kidney problems, this medicine can be used at the normal dose.

Hepatic impairment

It is unknown whether this medicine can be taken safely if you have liver problems. Consult your doctor if you have any liver problems.

Method of administration:

Oral use.

The tablet should be swallowed with a glass of water before meals.

The tablet can be divided into equal doses.

If you take more Melgama than you should

If you take more of this medicine than you should, consult your doctor or pharmacist, who will advise you on the necessary measures. No cases of benfotiamine overdose have been reported. In general, excess water-soluble vitamins, such as vitamin B1, are easily excreted in the urine, so no toxic effects of doses higher than recommended are expected.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Melgama

Do not take a double dose to make up for forgotten doses.

If you stop taking Melgama

You should always consult your doctor or pharmacist before stopping treatment.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Frequency not known (cannot be estimated from the available data):

  • Allergic reactions (rash, itching, skin allergic reactions)
  • Nausea or other stomach or intestinal disorders

Reporting of side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Medicines Monitoring System, www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Melgama

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton or blister after EXP. The expiry date is the last day of the month indicated.

Store in the original packaging to protect from light.

Medicines should not be disposed of via wastewater or household waste. Dispose of the packaging and any unused medicine in the pharmacy's SIGRE point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Package contents and additional information

Composition of Melgama

  • The active ingredient is benfotiamine. Each tablet contains 300 mg of benfotiamine.
  • The other ingredients are: microcrystalline cellulose, talc, povidone K30, colloidal anhydrous silica, high-partial-glycerides, and sodium croscarmellose in the tablet core; and hypromellose 15 mPa·s, talc, titanium dioxide (E 171), hypromellose 3 mPa·s, hypromellose 6 mPa·s, hypromellose 50 mPa·s, macrogol 3350, and sodium saccharin in the film coating.

Appearance of the product and package contents

White, oblong, film-coated tablets with a break line on both sides (approx. dimensions 18.5 mm x 6.5 mm).

Melgama is available in blister packs (PVC/PVDC/Al) in a carton.

Packs of 1, 10, 30, 60, 90, or 100 film-coated tablets.

Clinical packs of 500, 1,000, or 5,000 film-coated tablets.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

AAA-Pharma GmbH

Flugfeld-Allee 24

71034 Böblingen

Germany

Manufacturer

Dragenopharm Apotheker Püschl GmbH

Göllstraße 1

84529 Tittmoning

Germany

This medicine is authorised in the Member States of the European Economic Area under the following names:

Austria milgamma protect 300 mg Filmtabletten

Spain Melgama 300 mg film-coated tablets

Date of the last revision of this package leaflet:03.2025.

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS): http://www.aemps.gob.es/

Online doctors for MELGAMA 300 MG FILM-COATED TABLETS

Discuss questions about MELGAMA 300 MG FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (140)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
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Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • sexually transmitted infections, erectile dysfunction;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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€55
5.0 (2)
Doctor

Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

Patients commonly seek her help for:

  • High blood pressure, headaches, dizziness, swelling, palpitations.
  • Diagnosis and management of hypertension, arrhythmias, and tachycardia.
  • Metabolic syndrome, excess weight, high cholesterol.
  • Chronic fatigue, insomnia, poor concentration, anxiety.
  • Respiratory symptoms: colds, flu, sore throat, cough, fever.
  • Digestive issues: heartburn, bloating, constipation, IBS symptoms.
  • Chronic conditions: diabetes, thyroid disorders.
  • Interpretation of lab tests and medical reports, therapy adjustment.
  • Second opinion and decision-making support.
  • Cardiovascular disease prevention and metabolic risk reduction.
  • Long-term follow-up and dynamic health monitoring.

Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for MELGAMA 300 MG FILM-COATED TABLETS?
MELGAMA 300 MG FILM-COATED TABLETS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in MELGAMA 300 MG FILM-COATED TABLETS?
The active ingredient in MELGAMA 300 MG FILM-COATED TABLETS is benfotiamine. This information helps identify medicines with the same composition but different brand names.
Who manufactures MELGAMA 300 MG FILM-COATED TABLETS?
MELGAMA 300 MG FILM-COATED TABLETS is manufactured by Aaa-Pharma Gmbh. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of MELGAMA 300 MG FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MELGAMA 300 MG FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to MELGAMA 300 MG FILM-COATED TABLETS?
Other medicines with the same active substance (benfotiamine) include BENERVA 100 mg/ml INJECTABLE SOLUTION, BENERVA 300 mg FILM-COATED TABLETS, SURMENALIT 200 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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