MEDIKARB 100 % V/V MEDICINAL GAS LIQUID
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How to use MEDIKARB 100% V/V MEDICINAL GAS LIQUID
Contents of the leaflet
- Introduction
- What is Medikarb and what is it used for
- What you need to know before you start using Medikarb
- How to use Medikarb
- Possible side effects
- Storage of Medikarb
- Contents of the pack and further information
Introduction
Package Leaflet: Information for the User
Medikarb, 100% V/V medicinal liquid gas
Carbon dioxide
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
- Keep this leaflet, you may need to read it again.
- If you have any further questions, ask your doctor, pharmacist, or nurse.
- This medicine has been prescribed for you only, do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
- If you experience any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.
Contents of the package leaflet
- What is Medikarb and what is it used for
- What you need to know before you start using Medikarb
- How to use Medikarb
- Possible side effects
- Storage of Medikarb
- Contents of the pack and further information
1. What is Medikarb and what is it used for
Medikarb is a medicinal liquid gas, supplied in high-pressure gas cylinders. This medicine is used in the following situations:
- to stimulate breathing after a period of lack of breathing or controlled breathing
- to prevent a reduced concentration of carbon dioxide in the blood during hyperventilation
- to inflate body cavities during surgical procedures (such as laparoscopic surgery)
- during complementary body examinations
- to create a foam for use in the treatment of varicose veins
If you are given Medikarb by inhalation, it will always be given with medicinal oxygen.
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2. What you need to know before you start using Medikarb
Medikarb is administered exclusively in hospitals or medical centers under the supervision of medical, pharmaceutical, or nursing staff. Make sure your healthcare professional is aware of any conditions you have.
Do not use Medikarb
- if you have high acidity in the blood or tissues.
Warnings and precautions
Talk to your doctor, pharmacist, or nurse before you start using Medikarb.
Be particularly careful with Medikarb
- if you have any condition that causes difficulty breathing
- if you have previously undergone surgery or suffered trauma to the body to prevent the formation of bubbles in the body
- in case of hypovolemia
Other medicines and Medikarb
Medikarb may affect other medicines in the body, such as those used to treat hypertension, anticonvulsants, analgesics, and muscle relaxants.
Do not use this medicine with epinephrine or similar medicines.
Medikarb should not be used with nitrous oxide or similar anesthetics.
Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicine.
Pregnancy and breastfeeding
Medikarb should not be used during pregnancy.
Breastfeeding should be avoided during the use of Medikarb or if you are near this medicine.
If you are pregnant, think you might be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.
Driving and using machines
You can drive and use machines after using Medikarb if your healthcare professional considers you are in good condition and able to do so.
3. How to use Medikarb
Your doctor, pharmacist, or nurse will ensure that your Medikarb supply is suitable for you and that the equipment is correctly set up for you to receive the correct amount of gas.
Administration of Medikarb by inhalation in the form of a mixture with other medicinal gases is applied using a respiratory mask, a mouthpiece, or an endotracheal tube (which is inserted into the airways).
Special medical equipment will be used:
- to inflate parts of your body during laparoscopic surgery or gynecological procedures,
- to treat varicose veins
If you use more Medikarb than you should
When this medicine is administered at concentrations above 5%, it can cause extreme difficulty breathing, increased blood pressure, nausea, vomiting, and occasionally loss of consciousness. In case of overdose, your doctor, pharmacist, or nurse will stop administration and provide appropriate care. Contact with the product can cause burns or frostbite.
If you have any questions, talk to your doctor, pharmacist, or nurse.
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4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Possible side effects are:
- difficulty breathing, dry cough, increased blood pressure and heart rate, headache, tingling, alteration of taste, and nausea, if administered at a concentration below 5%;
- dizziness, sweating, alteration of vision and hearing, anxiety, and confusion, if administered at a concentration above 5%;
- seizures and loss of consciousness, if administered at a concentration above 10%.
Less common side effects are:
- cardiac arrest, which means the heart stops beating temporarily. It can be fatal if the cardiac arrest is not treated immediately;
- alteration of heart rhythm, when high levels of carbon dioxide enter the blood during laparoscopy;
- heart attacks due to gas bubbles in the bloodstream.
Reporting of side effects
If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if they are not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Agency's website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.
5. Storage of Medikarb
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label after EXP. The expiry date is the last day of the month shown.
The gas cylinders should be stored:
- at a temperature between -20°C and +65°C;
- covered and protected from adverse weather conditions;
- in a well-ventilated area, used exclusively for the storage of medicinal gases;
- separated from gas cylinders containing other gases or different in composition;
- protected from falls and other types of impact;
- away from heat sources. The valves of the gas cylinders are equipped with a rupture disc to prevent the cylinder from cracking due to excessive pressure. The rupture disc may fail in case of excessive temperature. This would cause the release of the entire contents of the cylinder. In that case, do not enter the storage area and ventilate the area well until an expert certifies it is safe.
Empty gas cylinders should be stored separately. Return empty gas cylinders to the supplier.
6. Contents of the pack and further information
Composition of Medikarb
- The active substance is medicinal carbon dioxide, 100% V/V.
- It does not contain excipients.
Appearance of Medikarb and contents of the pack
Medikarb is a medicinal liquid gas, colorless and odorless. This medicine is stored under pressure in gas cylinders made of steel or aluminum. The body of the cylinder is white and the valve is gray.
The gas cylinders with a capacity of x liters provide y (unit of volume) of carbon dioxide gas at 15°C and 1 bar (see table).
Not all pack sizes may be marketed.
Capacity of the gas cylinder (x) in liters | Nominal filling weight (kg) | Volume of carbon dioxide gas (y) in m3at 15°C and 1bar |
0.5 | 0.375 | 0.203 |
0.6 | 0.450 | 0.244 |
1 | 0.750 | 0.406 |
2 | 1.50 | 0.812 |
3 | 2.25 | 1.22 |
4 | 3.00 | 1.62 |
5 | 3.75 | 2.03 |
6 | 4.50 | 2.44 |
7 | 5.25 | 2.84 |
8 | 6.00 | 3.25 |
10 | 7.50 | 4.06 |
13.4 | 10.0 | 5.41 |
15 | 11.3 | 6.09 |
20 | 15.0 | 8.12 |
25 | 18.8 | 10.2 |
30 | 22.5 | 12.2 |
40 | 30.0 | 16.2 |
50 | 37.5 | 20.3 |
9X50 | 338 | 183 |
11X50 | 413 | 223 |
12X50 | 450 | 244 |
Marketing authorization holder and manufacturer
Marketing authorization holder:
S.E. de Carburos Metálicos, S.A., Av. De la Fama, 1, 08940 Cornellà de Llobregat, Spain
Manufacturers:
S.E. de Carburos Metálicos, S.A., Carretera de Toledo, 7, 28300 Aranjuez, Spain
Air Products S.A.S., 21 Rue de l'Epinoy, Zone Industrielle de l’Epinoy, 59175 Templemars, France
This medicine is authorized in the Member States of the European Economic Area under the following names:
Spain: Medikarb 100% V/V medicinal liquid gas
Portugal: Medikarb, 100% V/V, medicinal gas, liquefied
Date of last revision of this leaflet: 12/2022
Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/
- Country of registration
- Dosage formPULMONARY INHALATION, 100 % (V/V)
- ATC codeV03AN02
- Active substance
- Prescription requiredYes
- Manufacturer
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to MEDIKARB 100% V/V MEDICINAL GAS LIQUIDDosage form: PULMONARY INHALATION, 100% V/V ambient airActive substance: medical airManufacturer: Linde Gas Espana S.A.U.Prescription requiredDosage form: PULMONARY INHALATION, 22% w/w PackageActive substance: medical airManufacturer: Sociedad Española De Carburos Metalicos S.A.Prescription requiredDosage form: PULMONARY INHALATION, 21-22.5% v/vActive substance: oxygenManufacturer: Nippon Gases Espana SluPrescription required
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Frequently Asked Questions
MEDIKARB 100% V/V MEDICINAL GAS LIQUID requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
The active ingredient in MEDIKARB 100% V/V MEDICINAL GAS LIQUID is carbon dioxide. This information helps identify medicines with the same composition but different brand names.
MEDIKARB 100% V/V MEDICINAL GAS LIQUID is manufactured by Sociedad Española De Carburos Metalicos S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether MEDIKARB 100% V/V MEDICINAL GAS LIQUID is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.
You can buy MEDIKARB 100% V/V MEDICINAL GAS LIQUID in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.
To obtain a prescription, you can use Oladoctor:
Other medicines with the same active substance (carbon dioxide) include MEDICAL AIR COMPRESSED GAS LINDE 200 BAR, COMPRESSED MEDICAL GAS, SYNTHETIC MEDICAL AIR METAL CARBIDES, 22% V/V, MEDICAL GAS, COMPRESSED, SYNTHETIC MEDICAL AIR NIPPON GASES 200 BAR, COMPRESSED MEDICAL GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
