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LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS

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About the medicine

How to use LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Lamivudine Accord 100 mg film-coated tablets EFG

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What is Lamivudine Accord and what is it used for
  2. What you need to know before you take Lamivudine Accord
  3. How to take Lamivudine Accord
  4. Possible side effects
  5. Storage of Lamivudine Accord
  6. Contents of the pack and other information

1. What is Lamivudine Accord and what is it used for

Lamivudine Accord is used to treat long-term (chronic) hepatitis B infection in adults.

The active substance of Lamivudine Accord is lamivudine. Lamivudine Accord is an antiviral medicine that inhibits the hepatitis B virus and belongs to a group of medicines called nucleoside analogue reverse transcriptase inhibitors (NRTIs).

The hepatitis B virus infects the liver, causes long-term infection, and can cause liver damage. Lamivudine Accord can be used in patients whose liver is damaged but still functions normally (compensated liver disease) and in patients whose liver is damaged and does not function normally (decompensated liver disease).

Treatment with Lamivudine Accord may reduce the amount of hepatitis B virus in your body. This can lead to a reduction in liver damage and an improvement in liver function. Not everyone responds to treatment with Lamivudine Accord in the same way. Your doctor will monitor the effectiveness of the treatment.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Lamivudine Accord

Your healthcare professional should offer you advice and screening for HIV before starting treatment with lamivudine for hepatitis B infection and during treatment. If you have or contract HIV infection, see section 3.

Do not take Lamivudine Accord:

  • If you are allergicto lamivudine or any of the other ingredients of this medicine (listed in section 6).

Consult your doctorif you think this applies to you.

Warnings and precautions

Consult your doctor or pharmacist before starting treatment with Lamivudine Accord.

Some people taking Lamivudine Accord or similar medicines have a higher risk of experiencing serious side effects. You need to know that there is a higher risk:

  • if you have ever had other types of liver disease, such as hepatitis C.
  • if you are overweight(especially if you are a woman).
  • Consult your doctorif you have any of these conditions. You may need additional tests, such as blood tests, while taking this medicine. See section 4 for more information.

Do not stop taking Lamivudine Accordwithout your doctor's advice, as there is a risk that your hepatitis may worsen. When you stop taking Lamivudine Accord, your doctor will monitor you for at least four months to check for any problems. This will involve taking blood samples to check for any abnormal liver enzymes indicating liver damage. See section 3 for more information on how to take Lamivudine Accord.

Protect others

Hepatitis B is transmitted by having sexual contact with someone who has the disease or by transferring infected blood (e.g., by sharing needles). Lamivudine Accord does not prevent the risk of transmitting hepatitis B infection to others. To prevent others from getting infected with hepatitis B:

  • Use a condomwhen having oral or penetrative sex.
  • Avoid the risk of blood transfer— for example, do not share needles.

Taking Lamivudine Accord with other medicines

Tell your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including those obtained without a prescription, including herbal medicines.

Remember to tell your doctor or pharmacist if you start taking any other medicine while taking Lamivudine Accord.

These medicines must not be taken with Lamivudine Accord:

  • medicines (usually liquids) that contain sorbitol and other polyalcohols (such as xylitol, mannitol, lactitol, or maltitol), if taken regularly.
  • other medicines that contain lamivudine, used to treat HIV infection(sometimes also called AIDS virus).
  • emtricitabine used to treat HIV or hepatitis B infection.
  • cladribine, used to treat hairy cell leukemia.

Tell your doctorif you are being treated with any of these medicines.

Pregnancy and breastfeeding

Pregnancy

If you are pregnant, become pregnant, or are planning to become pregnant:

  • Talk to your doctor immediatelyabout the risks and benefits of taking Lamivudine Accord during pregnancy.

Do not stop treatment with Lamivudine Accord without your doctor's advice.

Breastfeeding

The components of Lamivudine Accord may pass into breast milk. If you are breastfeeding or thinking of breastfeeding:

  • Talk to your doctorbefore taking Lamivudine Accord.

Driving and using machines

Lamivudine Accord may make you feel tired, which could affect your ability to drive or use machines.

  • Do not drive or use machines unless you are sure it does not affect you.

Lamivudine Accord contains isomalt

If your doctor has told you that you have an intolerance to some sugars, consult them before taking this medicine.

3. How to take Lamivudine Accord

Follow exactly the instructions for administration of this medicine given by your doctor. Consult your doctor or pharmacist if you have any doubts.

Keep regular contact with your doctor

Lamivudine Accord helps control your hepatitis B infection. You need to continue taking it every day to control the infection and prevent it from getting worse.

  • Keep in touch with your doctor and do not stop taking Lamivudine Accordwithout your doctor's advice.

How much to take

The recommended doseis one tablet (100 mg of lamivudine) once a day.

Your doctor may prescribe a lower dose if you have kidney problems. Lamivudine oral solution is available for people who need a lower dose than usual or who cannot take tablets.

  • Talk to your doctorif you are in this situation.

Patients who also have or may contract HIV infection

If you have or contract untreated HIV infection while taking lamivudine for hepatitis B treatment, the HIV virus may develop resistance to certain HIV medicines and become more difficult to treat. Lamivudine is also used to treat HIV infection. Talk to your doctor if you have HIV infection. Your doctor may treat you with another medicine that contains a higher dose of lamivudine, usually 150 mg twice a day, as the lower dose of 100 mg of lamivudine is not sufficient to treat HIV infection. If you plan to change your HIV treatment, discuss it with your doctor first.

  • Talk to your doctorif you are in this situation.

Swallow the tablet whole with water. Lamivudine Accord can be taken with or without food.

If you take more Lamivudine Accord than you should

If you accidentally take too much Lamivudine Accord, contact your doctor or pharmacist, or go to the emergency department of the nearest hospital for advice. If possible, show them the Lamivudine Accord packaging. You can also call the Toxicology Information Service, phone: 91 562 04 20, indicating the medicine and the amount taken.

If you forget to take Lamivudine Accord

If you forget to take a dose, take it as soon as you remember. Then continue taking it as before. Do not take a double dose to make up for forgotten doses.

If you stop taking Lamivudine Accord

Do not stop taking Lamivudine Accord without consulting your doctor. There is a risk that your hepatitis may worsen (see “Warnings and precautions” in section 2). When you stop taking Lamivudine Accord, your doctor will monitor you for at least four months to check for any problems. This means that they will take blood samples to check that the level of any liver enzyme is not elevated, which can indicate liver damage.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The most common side effects reported in clinical trials with Lamivudine Accord were fatigue, respiratory tract infections, sore throat, headache, discomfort, and stomach pain, nausea, vomiting, and diarrhea, increased liver enzymes, and increased muscle enzymes (see below).

Allergic reaction

This is very rare (may affect up to 1 in 1000 people). The signs include:

  • swelling of the eyelids, face, or lips.
  • difficulty swallowing or breathing.
  • Contact a doctor immediatelyif you have these symptoms. Stop taking Lamivudine Accord.

Side effects that are thought to be caused by Lamivudine Accord:

A very common side effect(may affect more than 1 in 10people) that may appear in blood tests is:

  • an increase in the levels of some liver enzymes (transaminases), which may be a sign of liver inflammation or damage.

A common side effect(may affect up to 1 in 10people) is:

  • muscle cramps and pain.
  • skin rash or “hives” anywhere on the body.

A common side effectthat may appear in blood tests is:

  • An increase in the level of a muscle enzyme (creatine phosphokinase) that may be a sign of muscle damage.

A very rare side effect(may affect up to 1 in 10,000people) is:

  • Lactic acidosis (excess lactic acid in the blood).

Other side effects

Other side effects have been reported in a small number of people, but their exact frequency is unknown:

  • muscle breakdown.
  • worsening of liver disease if the hepatitis B virus becomes resistant to Lamivudine Accord or treatment is stopped. This can be fatal in some people.

A side effect that may appear in blood tests is:

  • a decrease in the number of cells involved in blood clotting (thrombocytopenia).

If you get side effects

Talk to your doctor or pharmacist.This includes any possible side effects not listed in this leaflet.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible that they are not listed in this leaflet. You can also report side effects directly through the Spanish Medicines Monitoring System for Human Use, www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Lamivudine Accord

Keep this medicine out of the sight and reach of children.

Do not take this medicine after the expiry date which is stated on the packaging after EXP. The expiry date is the last day of the month shown.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Return the packaging and any unused medicine to a pharmacy for disposal. If you are in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Lamivudine Accord

The active substance is lamivudine. Each film-coated tablet contains 100 mg of lamivudine.

The other ingredients are: isomalt (E953), crospovidone, magnesium stearate (E572), hypromellose (E464), titanium dioxide (E171), macrogol 400, polysorbate 80 (E433), and iron oxide yellow and red (E172).

Appearance and packaging of the product

Lamivudine Accord 100 mg film-coated tablets EFG are presented in Alu/PVC-Alu-OPA blisters containing 28 or 84 tablets.

The tablets are film-coated, pink, capsule-shaped, biconvex, with dimensions of 12.00 x 6.00 mm, scored on both sides with the code ''37'' on one side and ''I'' on the other side.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Accord Healthcare S.L.U.

World Trade Center

Moll de Barcelona, s/n

Edifici Est, 6ª planta

08039 Barcelona-Spain

Manufacturer

Pharmadox Healthcare Ltd.

KW 20A - Kordin Industrial Park

PLA 3000 Paola

Malta

This medicine is authorised in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:

Countries

Medicine name

Spain

Lamivudine Accord 100 mg, film-coated tablets EFG

United Kingdom (NI)

Lamivudine 100 mg Film-coated tablets

Netherlands

Lamivudine Accord 100 film-coated tablets

Date of last revision of this leaflet:June 2025

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

Online doctors for LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS

Discuss questions about LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

  • Diagnosis and treatment of acute and chronic conditions (high blood pressure, diabetes, respiratory infections, cardiovascular symptoms)
  • Evaluation of symptoms and guidance on further diagnostic testing
  • Preventive check-ups and regular health monitoring
  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
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  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
  • gastrointestinal complaints (nausea, diarrhoea, abdominal pain, gastroenteritis)
  • sudden changes in how a child or adult feels
  • questions about existing treatment and whether adjustments are needed
  • renewal of prescriptions when clinically appropriate
Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

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  • allergic rhinitis and chronic nasal symptoms
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  • general family medicine concerns
Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

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Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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Frequently Asked Questions

Is a prescription required for LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS?
LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS?
The active ingredient in LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS is lamivudine. This information helps identify medicines with the same composition but different brand names.
Who manufactures LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS?
LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS is manufactured by Accord Healthcare S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to LAMIVUDINE ACCORD 100 mg FILM-COATED TABLETS?
Other medicines with the same active substance (lamivudine) include EPIVIR 10 mg/mL ORAL SOLUTION, EPIVIR 150 MG FILM-COATED TABLETS, EPIVIR 150 MG FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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