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KYTRIL 3mg/3mL Injectable Solution

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use KYTRIL 3mg/3mL Injectable Solution

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Kytril 3mg/3ml injectable solution

Granisetron

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Kytril and what is it used for
  2. What you need to know before you use Kytril
  3. How to use Kytril
  4. Possible side effects
  5. Storage of Kytril
  6. Contents of the pack and other information

1. What is Kytril and what is it used for

Kytril contains the active substance granisetron. This belongs to a group of medicines called serotonin receptor antagonists, 5-HT3, or antiemetics, which means they prevent or stop nausea and vomiting.

Kytril is used to prevent and treat nausea and vomiting caused by certain treatments, such as chemotherapy or radiotherapy in anticancer therapy, as well as to treat and prevent post-operative nausea and vomiting.

The injectable solution is indicated in adults and children aged 2 years and older.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Kytril

Do not use Kytril

? if you are allergic (hypersensitive) to granisetron or any of the other ingredients of Kytril (listed in section 6: Further information).

If you are not sure, consult your doctor, nurse or pharmacist before receiving the injection.

Warnings and precautions

Consult your doctor, nurse or pharmacist before starting to use Kytril, especially if you:

? have problems with constipation due to intestinal obstruction

? have heart problems, are receiving anticancer medicines that can be harmful to your heart, and/or have some disorder of salt levels such as potassium, sodium or calcium (electrolyte disturbances).

? are taking another medicine from the group of “5-HT3 receptor antagonists”. This group includes dolasetron and ondansetron, used, like Kytril, for the treatment and prevention of nausea and vomiting.

Serotonin Syndrome is a rare but potentially life-threatening reaction that can occur with granisetron (see section 4). It can cause serious changes in how your brain, muscles, and digestive system work. The reaction can occur if you take granisetron alone,butit is more likely to occur if you take granisetron with other medicines (in particular fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram, venlafaxine, duloxetine). The risk of serotonin syndrome also increases if you are taking medicines that contain buprenorphine or other opioids. Make sure to tell your doctor, nurse or pharmacist all the medicines you are taking.

Other medicines and Kytril

Tell your doctor, nurse or pharmacist if you are using or have recently used or might use other medicines, even those bought without a prescription. This is because Kytril may interact with some medicines. Also, some medicines may interact with this injection.

Tell your doctor, nurse or pharmacist if you are taking or might take other medicines:

? medicines used to treat irregular heartbeats, other “5-HT3 receptor antagonists” such as dolasetron or ondansetron (see “Warnings and precautions”).

? phenobarbital, a medicine used to treat epilepsy

? ketoconazole, a medicine used to treat fungal infections

? erythromycin, an antibiotic used to treat bacterial infections

? SSRIs (selective serotonin reuptake inhibitors) used to treat depression and/or anxiety. For example: fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram

? SNRIs (serotonin and norepinephrine reuptake inhibitors) used to treat depression and/or anxiety. For example: venlafaxine, duloxetine

  • Medicines that contain buprenorphine or other opioids.

Pregnancy and breastfeeding

Do not receive this injection if you are pregnant, trying to become pregnant or breastfeeding, unless your doctor has told you to.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor, nurse or pharmacist for advice before using this medicine.

Driving and using machines

Kytril is not expected to affect your ability to drive or use machines.

Kytril contents

Kytril contains less than 1 mmol of sodium (23 mg) per dose (3mg/3ml), i.e., essentially “sodium-free”.

3. How to use Kytril

The injection will be given to you by your doctor or nurse. The recommended dose of Kytril varies from one patient to another. This depends on age, weight, and whether you are taking other medicines to prevent or treat nausea and vomiting. Your doctor will decide how much to give you.

Kytril can be given as an injection into the veins (intravenously).

Prevention of nausea or vomiting after radiotherapy or chemotherapy

You will be given the injection before you start radiotherapy or chemotherapy. The injection into the veins (intravenously) will last between 30 seconds to 5 minutes and the usual dose is between 1 and 3 mg. The medicine may be diluted before injection.

Treatment of nausea or vomiting after radiotherapy or chemotherapy

The injection will last between 30 seconds to 5 minutes and the usual dose is between 1 and 3 mg. The medicine may be diluted before injection into the veins (intravenously). To stop the discomfort, you may receive more injections after the first dose. There must be at least 10 minutes between each dose. The maximum dose of Kytril will be 9 mg per day.

Combination with corticosteroids

The effect of the injection may be increased with the use of other medicines, called corticosteroids. This may be 8-20 mg of dexamethasone, given before the start of radiotherapy or chemotherapy treatment, or 250 mg of methylprednisolone given before the start of chemotherapy and again immediately after finishing it.

Use in children for the prevention or treatment of nausea or vomiting after radiotherapy or chemotherapy

Kytril is given by injection into the veins (intravenously) as described above, with the dose adjusted according to the child's weight. The injections are diluted and given before radiotherapy or chemotherapy and last 5 minutes. Children may receive a maximum of 2 doses per day, with at least 10 minutes between each dose.

Treatment of nausea or vomiting after an operation

The injection into the veins (intravenously) will last between 30 seconds and 5 minutes and the usual dose is 1 mg. The maximum dose of Kytril is 3 mg per day.

Use in children for the prevention or treatment of nausea or vomiting after an operation

This injection should not be given for the treatment of nausea or discomfort after an operation.

If you use more Kytril than you should

Because this injection is given by a doctor or nurse, it is unlikely that you will receive more than the dose you should. However, if you are concerned, consult your doctor or nurse. Symptoms of overdose include a mild headache (cephalalgia). You will be treated according to your symptoms.

If you have any further questions on the use of this product, ask your doctor, nurse or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. If you notice any of the following side effects, you should see your doctor immediately:

? Allergic reactions (anaphylaxis). The signs may include swelling of the throat, or your face, lips, and mouth becoming swollen, and difficulty breathing or swallowing.

  • Serotonin Syndrome. The signs may include diarrhea, nausea, vomiting, high temperature and blood pressure, excessive sweating, and rapid heartbeat, agitation, confusion, hallucination, shivering, muscle tremors, shaking or stiffness, loss of coordination, and restlessness. This reaction can occur if you take Kytril alone or, more likely, with other medicines (see “Warnings and precautions“).

Other side effects that may occur while taking this medicine are:

Very common: may affect more than 1 in 10 people

? headache

? constipation. Your doctor will monitor your condition.

Common: may affect up to 1 in 10 people

? difficulty sleeping (insomnia)

? blood tests show changes in liver function

? diarrhea

Uncommon: may affect up to 1 in 100 people

? skin rash or an allergic reaction or hives. The signs may include red patches that itch.

? changes in heartbeats (rhythm) and changes in the ECG (electrocardiogram).

? abnormal involuntary movements, such as tremors, muscle stiffness, and muscle contractions.

Reporting of side effects

If you experience any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Agency's website: https://www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Kytril

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the pack and/or ampoule after “EXP”. The expiry date is the last day of the month stated.

Kytril should be stored below 30°C to protect it from light.

After dilution, the diluted solution should be stored between 2°C and 8°C and used within 24 hours of dilution.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

Kytril composition

The active substance is granisetron.

Each ml of injectable solution contains 1 mg of granisetron (as granisetron hydrochloride).

The other ingredients are sodium chloride, water for injections, citric acid monohydrate, hydrochloric acid, and sodium hydroxideto adjust the pH (acidity).

Appearance of Kytril and pack contents

Kytril solution is a clear, colorless liquid, in transparent glass ampoules containing 3 ml of nominal volume. Each pack contains 1 or 5 ampoules. Not all pack sizes may be marketed.

Each 1 ml of Kytril solution contains 1 mg of granisetron (as granisetron hydrochloride).

Each 3 ml ampoule contains 3 mg of granisetron (as granisetron hydrochloride).

Preparation of the dilution

For single use. Dilute before use. The medicine requires dilution before administration by injection or infusion.

Other presentations:

Kytril 1 mg/1 ml injectable solution (hospital use)

Kytril 1 mg tablets (hospital diagnosis)

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Atnahs Pharma Netherlands B.V.

Copenhagen Towers

Ørestads Boulevard 108, 5.tv

DK-2300 København S

Denmark

Manufacturer

Cenexi

52, rue M. et J. Gaucher

94120 Fontenay-sous-Bois

France

This medicine is authorised in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:

Austria, Belgium, Czech Republic, Estonia, Finland, France, Ireland, Italy, Latvia, Netherlands, Slovak Republic, Slovenia, Spain, United Kingdom (Northern Ireland): Kytril

Germany: Kevatril

Date of last revision of this leaflet: March 2025

Other sources of information

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for KYTRIL 3mg/3mL Injectable Solution

Discuss questions about KYTRIL 3mg/3mL Injectable Solution, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Antonio Cayatte

General medicine 44 years exp.

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic. His clinical background includes: 

  • assessment of sudden or unclear symptoms
  • ongoing care for chronic conditions
  • follow-up after hospital discharge
  • interpretation of test results
  • medical support while abroad

Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association. Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Dr. Antonio Cayatte provides comprehensive care for a broad spectrum of common health concerns, including:

  • Respiratory & ENT: acute bronchitis, concerns related to pneumonia, sinusitis, tonsillitis, ear infections, sore throat conditions, and allergic rhinitis
  • Eye Health: allergic and infectious conjunctivitis, as well as red or irritated eyes
  • Digestive & Urinary: gastroesophageal reflux disease (GERD), gastritis, urinary tract infections, and cystitis
  • Chronic Conditions: hypertension, elevated cholesterol, and structured weight management planning
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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

5.0 (43)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

5.0 (195)
Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

Get KYTRIL 3mg/3mL Injectable Solution Prescription Online

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Frequently Asked Questions

Is a prescription required for KYTRIL 3mg/3mL Injectable Solution?

KYTRIL 3mg/3mL Injectable Solution requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in KYTRIL 3mg/3mL Injectable Solution?

The active ingredient in KYTRIL 3mg/3mL Injectable Solution is granisetron. This information helps identify medicines with the same composition but different brand names.

Who manufactures KYTRIL 3mg/3mL Injectable Solution?

KYTRIL 3mg/3mL Injectable Solution is manufactured by Atnahs Pharma Netherlands Bv.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of KYTRIL 3mg/3mL Injectable Solution online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether KYTRIL 3mg/3mL Injectable Solution is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy KYTRIL 3mg/3mL Injectable Solution in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy KYTRIL 3mg/3mL Injectable Solution in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to KYTRIL 3mg/3mL Injectable Solution?

Other medicines with the same active substance (granisetron) include GRANISETRON ALTAN 3 mg/50 ml SOLUTION FOR INFUSION, GRANISETRON AUROVITAS SPAIN 1 mg FILM-COATED TABLETS, GRANISETRON KABI 1 mg/ml CONCENTRATE FOR INJECTION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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