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Ketobrill 0,25 mg/ml colirio

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A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS

Contents of the leaflet

  1. Introduction
  2. What is Ketobrill and what is it used for
  3. What you need to know before you use Ketobrill
  4. How to use Ketobrill
  5. Possible side effects
  6. Storage of Ketobrill
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

Ketobrill 0.25 mg/ml eye drops, solution in single-dose container

Ketotifen

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Ketobrill and what is it used for
  2. What you need to know before you use Ketobrill
  3. How to use Ketobrill
  4. Possible side effects
  5. Storage of Ketobrill
  6. Contents of the pack and further information

1. What is Ketobrill and what is it used for

Ketobrill contains the active substance ketotifen hydrogen fumarate, which is an antiallergic substance. Ketobrill is used to treat the ocular symptoms of seasonal allergic conjunctivitis (hay fever).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Ketobrill

Do not use Ketobrill

  • If you are allergic to ketotifen hydrogen fumarate or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before you start using Ketobrill.

Children

Safety and efficacy in children under 3 years have not been established.

Other medicines and Ketobrill

If you need to apply any other eye medicine besides Ketobrill, wait at least 5 minutes between applying each product.

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. This is especially important with medicines used to treat:

  • depression, anxiety and sleep disorders
  • allergy (e.g. antihistamines)

Using Ketobrill with alcohol

Ketobrill may increase the effects of alcohol.

Pregnancy and breastfeeding

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Ketobrill can be used during breastfeeding.

Driving and using machines

Ketobrill may cause blurred vision or drowsiness. If this happens, wait until the effects have gone before driving or using machines.

3. How to use Ketobrill

Follow exactly the administration instructions of this medicine given by your doctor. Ask your doctor or pharmacist if you have any doubts.

The recommended dose in adults, elderly and children (from 3 years onwards) is one drop in the affected eye(s) twice daily (in the morning and at night).

Use in children under 3 years

Safety and efficacy in children under 3 years have not been established.

A single-dose container contains a sufficient amount of solution to treat both eyes in one application.

Instructions for use

  1. Wash your hands.
  2. Open the aluminum bag and take out a strip of single-dose containers.
  3. Separate one single-dose container from the strip (Fig. 1).
  4. Put the remaining single-dose containers back in the aluminum bag and fold the edge of the bag. Keep the bag in the box.
  5. Open the single-dose container by twisting the top end. After opening the container, do not touch the tip of the dropper (Fig. 2).
  6. Tilt your head back (Fig. 3).
  7. Pull the lower eyelid down with your finger and hold the container with the other hand. Squeeze the container so that one drop falls into the eye (Fig. 4).
  8. Close your eyes and press the inner corner of your eye with the tip of your finger for 1-2 minutes. This prevents the drop from flowing down the tear duct into the throat and most of the drop stays in the eye (Fig. 5). If necessary, repeat steps 6 to 8 in the other eye.
  9. Discard the single-dose container after use.

Series of schematic illustrations showing the application of eye drops from different angles

Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5

If you have any further questions on the use of this product, ask your doctor or pharmacist.

If you use more Ketobrill than you should

If you accidentally take Ketobrill orally, it will not cause any harm, nor will it if more than one drop accidentally falls into your eye. In case of doubt, consult your doctor. Also, in case of overdose or accidental ingestion, you can contact the Toxicology Information Service Tel.: 91 596 04 20.

If you forget to use Ketobrill

If you forget to use Ketobrill, apply the treatment as soon as you remember. Then go back to your normal treatment schedule. Do not use a double dose to make up for forgotten doses.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported.

Common (may affect up to 1 in 10 people)

  • eye irritation or pain in the eye
  • inflammation in the eye
  • corneal epithelium injury

Uncommon (may affect up to 1 in 100 people)

  • blurred vision when applying the drops in the eye
  • dryness in the eye
  • alteration in the eyelid
  • conjunctivitis
  • increased sensitivity of the eyes to light
  • visible bleeding in the white part of the eye
  • headache
  • drowsiness
  • rash (which can also cause itching)
  • eczema (itching, redness, rash with itching)
  • dry mouth
  • allergic reaction (including swelling of the face and eyelids) and increased severity of an existing allergic condition such as asthma and eczema

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Agency website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Ketobrill

Keep out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and the aluminum bag after EXP and on the single-dose container after EXP. The expiry date is the last day of the month shown.

Do not store above 25°C. Do not refrigerate or freeze.

Keep the single-dose container in the aluminum bag.

Ketobrill does not contain preservatives. Once opened, the contents of the single-dose container should be used immediately and not stored. Discard the remaining solution in the single-dose container after application.

Discard Ketobrill 4 weeks after opening the aluminum bag.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Ketobrill

-The active substance is ketotifen (as hydrogen fumarate). Each ml contains 0.25 mg of ketotifen, corresponding to 0.345 mg of ketotifen hydrogen fumarate.

-The other ingredients (excipients) are glycerol (E422), sodium hydroxide (E524) (for pH adjustment) and water for injections.

Appearance and pack contents

Ketobrill is a clear, colorless solution. One single-dose container contains 0.4 ml.

Ketobrill is available in packs containing 5, 10, 20, 30, 50 and 60 single-dose containers.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Pharma Stulln GmbH

Werksstrasse 3

92551 Stulln

(Germany)

You can obtain further information on this medicine from the representative of the marketing authorisation holder:

BRILL PHARMA, S.L.

C/ Munner, 8

08022 Barcelona

(Spain)

This medicine is authorised in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:

Germany Allergo-Vision sine 0,25 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis

Austria Ketotifen Stulln 250 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis

Spain Ketobrill 0,25 mg/ml colirio en solución en envase unidosis

Ireland Ketofall 0.25 mg/ml eye drops, solution in single-dose container

Netherlands Ketotifen Stulln Unit Dose 0,25 mg/ml oogdruppels, oplossing in verpakking voor éénmalig gebruik

United Kingdom Ketofall 0.25 mg/ml eye drops, solution in single-dose container

(Northern Ireland)

Date of last revision of this leaflet: July 2022.

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS

Discuss questions about KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64

Frequently Asked Questions

KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is ketotifen. This information helps identify medicines with the same composition but different brand names.

The average pharmacy price for KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is around 5.06 EUR. Prices may vary depending on the manufacturer and dosage form.

KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is manufactured by Pharma Stulln Gmbh. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

The prescription is issued by a doctor after assessing your health. In Spain, KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.

To request a review, you can use Oladoctor:

Other medicines with the same active substance (ketotifen) include BENTIFEN 0.25mg/ml EYE DROPS SOLUTION, KETISAL 0.25 mg/ml EYE DROPS SOLUTION, KETOTIFEN CODRAMOL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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