Skip to main content

KETOBRILL 0.25 mg/ml Eye Drops

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS

Contents of the leaflet

  1. Introduction
  2. What is Ketobrill and what is it used for
  3. What you need to know before you use Ketobrill
  4. How to use Ketobrill
  5. Possible side effects
  6. Storage of Ketobrill
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

Ketobrill 0.25 mg/ml eye drops, solution in single-dose container

Ketotifen

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Ketobrill and what is it used for
  2. What you need to know before you use Ketobrill
  3. How to use Ketobrill
  4. Possible side effects
  5. Storage of Ketobrill
  6. Contents of the pack and further information

1. What is Ketobrill and what is it used for

Ketobrill contains the active substance ketotifen hydrogen fumarate, which is an antiallergic substance. Ketobrill is used to treat the ocular symptoms of seasonal allergic conjunctivitis (hay fever).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Ketobrill

Do not use Ketobrill

  • If you are allergic to ketotifen hydrogen fumarate or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before you start using Ketobrill.

Children

Safety and efficacy in children under 3 years have not been established.

Other medicines and Ketobrill

If you need to apply any other eye medicine besides Ketobrill, wait at least 5 minutes between applying each product.

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. This is especially important with medicines used to treat:

  • depression, anxiety and sleep disorders
  • allergy (e.g. antihistamines)

Using Ketobrill with alcohol

Ketobrill may increase the effects of alcohol.

Pregnancy and breastfeeding

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Ketobrill can be used during breastfeeding.

Driving and using machines

Ketobrill may cause blurred vision or drowsiness. If this happens, wait until the effects have gone before driving or using machines.

3. How to use Ketobrill

Follow exactly the administration instructions of this medicine given by your doctor. Ask your doctor or pharmacist if you have any doubts.

The recommended dose in adults, elderly and children (from 3 years onwards) is one drop in the affected eye(s) twice daily (in the morning and at night).

Use in children under 3 years

Safety and efficacy in children under 3 years have not been established.

A single-dose container contains a sufficient amount of solution to treat both eyes in one application.

Instructions for use

  1. Wash your hands.
  2. Open the aluminum bag and take out a strip of single-dose containers.
  3. Separate one single-dose container from the strip (Fig. 1).
  4. Put the remaining single-dose containers back in the aluminum bag and fold the edge of the bag. Keep the bag in the box.
  5. Open the single-dose container by twisting the top end. After opening the container, do not touch the tip of the dropper (Fig. 2).
  6. Tilt your head back (Fig. 3).
  7. Pull the lower eyelid down with your finger and hold the container with the other hand. Squeeze the container so that one drop falls into the eye (Fig. 4).
  8. Close your eyes and press the inner corner of your eye with the tip of your finger for 1-2 minutes. This prevents the drop from flowing down the tear duct into the throat and most of the drop stays in the eye (Fig. 5). If necessary, repeat steps 6 to 8 in the other eye.
  9. Discard the single-dose container after use.

Series of schematic illustrations showing the application of eye drops from different angles

Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5

If you have any further questions on the use of this product, ask your doctor or pharmacist.

If you use more Ketobrill than you should

If you accidentally take Ketobrill orally, it will not cause any harm, nor will it if more than one drop accidentally falls into your eye. In case of doubt, consult your doctor. Also, in case of overdose or accidental ingestion, you can contact the Toxicology Information Service Tel.: 91 596 04 20.

If you forget to use Ketobrill

If you forget to use Ketobrill, apply the treatment as soon as you remember. Then go back to your normal treatment schedule. Do not use a double dose to make up for forgotten doses.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported.

Common (may affect up to 1 in 10 people)

  • eye irritation or pain in the eye
  • inflammation in the eye
  • corneal epithelium injury

Uncommon (may affect up to 1 in 100 people)

  • blurred vision when applying the drops in the eye
  • dryness in the eye
  • alteration in the eyelid
  • conjunctivitis
  • increased sensitivity of the eyes to light
  • visible bleeding in the white part of the eye
  • headache
  • drowsiness
  • rash (which can also cause itching)
  • eczema (itching, redness, rash with itching)
  • dry mouth
  • allergic reaction (including swelling of the face and eyelids) and increased severity of an existing allergic condition such as asthma and eczema

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines Agency website: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Ketobrill

Keep out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and the aluminum bag after EXP and on the single-dose container after EXP. The expiry date is the last day of the month shown.

Do not store above 25°C. Do not refrigerate or freeze.

Keep the single-dose container in the aluminum bag.

Ketobrill does not contain preservatives. Once opened, the contents of the single-dose container should be used immediately and not stored. Discard the remaining solution in the single-dose container after application.

Discard Ketobrill 4 weeks after opening the aluminum bag.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Ketobrill

-The active substance is ketotifen (as hydrogen fumarate). Each ml contains 0.25 mg of ketotifen, corresponding to 0.345 mg of ketotifen hydrogen fumarate.

-The other ingredients (excipients) are glycerol (E422), sodium hydroxide (E524) (for pH adjustment) and water for injections.

Appearance and pack contents

Ketobrill is a clear, colorless solution. One single-dose container contains 0.4 ml.

Ketobrill is available in packs containing 5, 10, 20, 30, 50 and 60 single-dose containers.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Pharma Stulln GmbH

Werksstrasse 3

92551 Stulln

(Germany)

You can obtain further information on this medicine from the representative of the marketing authorisation holder:

BRILL PHARMA, S.L.

C/ Munner, 8

08022 Barcelona

(Spain)

This medicine is authorised in the Member States of the European Economic Area and in the United Kingdom (Northern Ireland) under the following names:

Germany Allergo-Vision sine 0,25 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis

Austria Ketotifen Stulln 250 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis

Spain Ketobrill 0,25 mg/ml colirio en solución en envase unidosis

Ireland Ketofall 0.25 mg/ml eye drops, solution in single-dose container

Netherlands Ketotifen Stulln Unit Dose 0,25 mg/ml oogdruppels, oplossing in verpakking voor éénmalig gebruik

United Kingdom Ketofall 0.25 mg/ml eye drops, solution in single-dose container

(Northern Ireland)

Date of last revision of this leaflet: July 2022.

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS

Discuss questions about KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(36)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a family physician with specialized training in the management of chronic pain. He provides video consultations for adults in Spain and across Europe: whether you have been living with pain for months that no one has been able to properly explain, or you need to resolve a health issue without waiting weeks for an appointment.

His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

Book a video appointment
€86
Doctor
5.0(19)

Nuno Tavares Lopes

Family medicineGeneral medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management
  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses
  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment
  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance
  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis
  • Pain management: acute and chronic pain, post-surgical care
  • Public health: prevention, health screenings, long-term monitoring
  • Sick leave (Baixa médica) connected to Segurança Social in Portugal
  • IMT medical certificates for driving licence exchange
Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64
Doctor
0.0(0)

Muhammad Tayyab Altaf

General medicine3 years of experience

Dr. Muhammad Tayyab Altaf is a primary care physician with extensive international experience, offering online consultations for adults and children. His background includes clinical practice in Policlinico San Matteo Hospital Pavia in Italy, Mount Sinai Hospital in New York, United States and other healthcare settings, allowing him to manage a wide range of acute and chronic medical conditions with confidence and clarity.

His clinical expertise spans multi-system conditions, preventive care and long-term management of chronic diseases. Dr. Altaf combines hands-on experience with a strong research background in both medical and surgical fields, enabling him to provide accurate assessments and structured, evidence-based treatment plans. Patients value his ability to explain diagnoses clearly, outline next steps and support them in making informed healthcare decisions.

Online consultations with Dr. Altaf are suitable for many everyday and acute situations where a timely medical opinion can help determine the safest next steps. He evaluates and treats conditions affecting the cardiovascular, respiratory, gastrointestinal, neurological, haematological and endocrine systems. Common examples include:

  • hypertension and other blood pressure issues
  • ischaemic heart disease and angina
  • asthma, COPD and emphysema
  • pneumonia and lung fibrosis
  • gastroenteritis and digestive infections
  • liver conditions, including alcohol-related disease
  • epilepsy, seizures and post-stroke symptoms
  • dementia and cognitive decline
  • anaemia and other haematological changes
  • diabetes, thyroid disorders and pituitary disease
Many patients reach out when they experience new or worsening symptoms, fluctuations in blood pressure, non-severe chest discomfort, breathing symptoms, digestive issues, suspected infections, chronic fatigue or concerns that affect daily life. He also helps patients understand test results, adjust existing treatment plans and navigate long-term health strategies safely and effectively.

When clinically appropriate, Dr. Altaf can also provide health and fitness certificates, including documentation required for physical activity, sports participation or gym use, based on the patient’s health status and medical indications.

Some conditions are not suitable for online care. Severe chest pain, loss of consciousness, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack require immediate attention from local emergency services. Dr. Altaf prioritises patient safety and will guide you accordingly if your situation needs urgent in-person care.

In all consultations, Dr. Muhammad Tayyab Altaf focuses on clear communication, accurate diagnosis and patient-centred decision-making. His approach ensures that individuals and families feel informed, supported and confident in their next steps, no matter where they are.

Book a video appointment
€71

Get KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS Prescription Online

1

Fill in a 2-min form

Tell us your symptoms, history, and what medicine you're requesting.

2

Pick a doctor or let us assign

Choose a specialist or we'll match you with the next available doctor.

3

Doctor reviews your case

Usually within 30 minutes. They may ask follow-up questions via chat.

4

Collect from any pharmacy

Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is ketotifen. This information helps identify medicines with the same composition but different brand names.

The average pharmacy price for KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is around 5.06 EUR. Prices may vary depending on the manufacturer and dosage form.

KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is manufactured by Pharma Stulln Gmbh. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy KETOBRILL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (ketotifen) include BENTIFEN 0.25mg/ml EYE DROPS SOLUTION, KETISAL 0.25 mg/ml EYE DROPS SOLUTION, KETOTIFEN CODRAMOL 0.25 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media