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IONOLYTE SOLUTION FOR INFUSION

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About the medicine

How to use IONOLYTE SOLUTION FOR INFUSION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

Ionolyte solution for infusion

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack:

  1. What is Ionolyte and what is it used for
  2. What you need to know before you use Ionolyte
  3. How to use Ionolyte
  4. Possible side effects
  1. Storage of Ionolyte
  2. Contents of the pack and other information

1. What is Ionolyte and what is it used for

Ionolyte is a solution for infusion.

Ionolyte is used in the treatment of:

  • extracellular dehydration (loss of water)
  • hypovolemia (rapid decrease in circulating blood volume)
  • mild metabolic acidosis (increase in blood acidity caused by a metabolic disorder)
Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Ionolyte

Do not use Ionolyte:

  • if you are allergic to sodium acetate trihydrate, sodium chloride, potassium chloride, magnesium chloride hexahydrate or any of the other components of this medicine (listed in section 6).

Ionolyte should not be administered to you if you have:

  • hyperhydration (too much fluid in your body), especially in cases of pulmonary edema (fluid accumulation in the lungs) and congestive heart failure (the heart is unable to pump enough blood to the whole body)
  • severely impaired renal function
  • metabolic alkalosis (decrease in blood acidity caused by a metabolic disorder)
  • hyperkalemia (high potassium levels in the blood)

Your doctor should check this.

Be careful with Ionolyte if you have:

  • heart failure
  • a severe cardiac rhythm disorder
  • altered renal function
  • a severe electrolyte imbalance (e.g. high levels of potassium, sodium, magnesium or chloride in the blood)
  • high blood pressure
  • eclampsia (a complication of pregnancy characterized by high blood pressure and significant amounts of protein in the urine)
  • aldosteronism (a syndrome of high blood pressure and low potassium levels in the blood caused by an excess of a hormone called aldosterone)
  • you are receiving other treatments or have conditions related to sodium retention (e.g. corticosteroids, steroids)
  • you are taking potassium-sparing diuretics (used to increase urine volume)
  • you have severe potassium deficiency
  • you have taken high doses of digitalis (a medication used to treat heart conditions)

corazón)

  • you have myasthenia gravis (a disease that involves severe muscle weakness)
  • you have recently undergone surgery and a muscle relaxant (neuromuscular blockade) has been used
  • you are going to receive large volumes of this solution

Warnings and precautions

Consult your doctor, pharmacist or nurse before starting to use Ionolyte.

Children and adolescents

There are no special warnings and precautions.

Using Ionolyte with other medicines

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

Ionolyte is not recommended if you are taking/using:

  • corticosteroids/steroids and carbenoxolone (for the treatment of ulcers of the digestive system) as these are associated with sodium and water retention (with fluid accumulation in tissues and high blood pressure).
  • potassium-sparing diuretics (used to increase urine volume, such as amiloride, spironolactone, triamterene, administered alone or in combination)
  • angiotensin-converting enzyme inhibitors (ACE inhibitors) and angiotensin II receptor antagonists (medicines used primarily to control blood pressure, treatment of heart failure)
  • tacrolimus and cyclosporin (medicines used to prevent organ rejection)
  • muscle relaxants
  • salicylates (used to relieve pain and reduce fever)
  • lithium (antidepressant)
  • alkaline medicines such as sympathomimetics (e.g. amphetamines)

Using Ionolyte with food and drinks

Ionolyte has not shown any negative effects when administered at the same time as food and drink.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Ionolyte can be used safely during pregnancy and breastfeeding as long as electrolyte and fluid balance is monitored.

When another medicine is added to Ionolyte, the nature of the medicine and its use during pregnancy and breastfeeding should be considered independently. Your doctor will discuss this with you.

Driving and using machines

Ionolyte has no effect on the ability to drive or use machines.

3. How to use Ionolyte

Ionolyte will be administered to you in a hospital by a doctor or nurse.

You will receive your medicine by intravenous infusion (drip by drip through a vein). The volume and interval of the infusion that you are given will depend on your needs.

Your doctor will decide what dose is suitable for you to receive.

If you receive more Ionolyte than you should

It is very unlikely that you will receive more medicine than you should, because this medicine will be administered to you by your doctor or nurse who will monitor you during treatment. However, tell your doctor or nurse if you have any doubts.

In the event of an accidental overdose, treatment will be stopped and you will be monitored for any signs and symptoms related to the medicine. Therapeutic removal of excess fluid may be necessary.

In cases of overdose or accidental ingestion, consult the Toxicology Information Service, Telephone: 91-5620420

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Very common (may affect more than 1 in 10 people):

  • hyperhydration (too much fluid in your body) and heart failure in patients with heart disorders or pulmonary edema (fluid accumulation in the lungs)

Common (may affect up to 1 in 10 people, but less than 1 in 10 patients):

  • large volumes of this solution may lead to a dilution of blood components and decrease hematocrit (proportion of blood volume occupied by red blood cells)

Other side effects include:

  • fluid accumulation in tissues (edema)
  • fever
  • infection at the injection site, reaction or local pain
  • irritation of the veins, venous thrombosis (formation of a blood clot) or phlebitis (inflammation of the vein) extending from the injection site
  • extravasation (fluid loss from the vein)

You will be monitored by your doctor or nurse during treatment with this medicine. If any of these side effects appear, treatment will be stopped.

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Ionolyte

Do not refrigerate or freeze.

Keep this medicine out of the sight and reach of children.

The product should be used immediately once opened.

Do not use this medicine after the expiry date which is stated on the label after EXP. The expiry date is the last day of the month shown.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and other information

Composition of Ionolyte

The active substances are:

500 ml

1000 ml

Sodium acetate trihydrate

2.32 g

4.63 g

Sodium chloride

3.01 g

6.02 g

Potassium chloride

0.15 g

0.30 g

Magnesium chloride hexahydrate

0.15 g

0.30 g

Electrolytes:

Na+ 137.0 mmol/l

K+ 4.0 mmol/l

Mg++ 1.5 mmol/l

Cl- 110.0 mmol/l

CH3COO- 34.0 mmol/l

Theoretical osmolality: 286.5 mOsm/l

Titration acidity: < 2.5 mmol NaOH/l

pH: 6.9 – 7.9

The other ingredients are:

Water for injections

Sodium hydroxide (for pH adjustment)

Hydrochloric acid (for pH adjustment)

Appearance and packaging

Ionolyte is a clear and colorless solution presented in a sealed plastic container known as a freeflex®bag or in plastic bottles known as KabiPac®.

The solution is available in 500 ml or 1000 ml presentations.

Polyolefin bag (freeflex®) with overbag: 20 x 500 ml, 10 x 1000 ml

LDPE bottle (KabiPac®): 10 x 500 ml, 10 x 1000 ml

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder:

Fresenius Kabi España, S.A.U

C/ Marina 16-18

08005-BARCELONA (Spain)

Manufacturer:

Fresenius Kabi Deutschland GmbH

61169 Friedberg

Tel: +49 6172 686 8667

[email protected]

Fresenius Kabi France

6 rue du Rempart

27400 Louviers

Tel: +33 2 32 09 59 00

This medicine is authorised in the Member States of the European Economic Area under the following names:

Belgium

Ionolyte, oplossing voor infusie

Denmark

Ionolyte, infusionsvæske, opløsning

Slovakia

Isolyte, infúzny roztok

Spain

Ionolyte solución para perfusión

France

Ionoven, solution pour perfusion

Netherlands

Ionolyte, oplossing voor infusie

Hungary

Isolyte, oldatos infúzió

Norway

Ionolyte infusjonsvæske, oppløsning

Poland

Venolyte

Portugal

Ionoven solução para perfusão

Czech Republic

Isolyte, infuzní roztok

Sweden

Ionolyte, infusionsvätska, lösning

Date of last revision of this leaflet: February 2016

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This information is intended only for healthcare professionals:

Adults and pediatric population

The dose and rate of administration depend on the age, body weight, clinical and biological condition of the patient (including acid-base balance) and concomitant treatment.

Recommended dose:

The maximum daily dose depends on the patient's fluid and electrolyte needs.

To temporarily restore blood volume, a volume equivalent to 3-5 times the lost blood volume is required.

Usual recommended doses:

For adults, elderly and adolescents (from 12 years): 500 ml to 3 liters/24 hours.

For infants and children (from 28 days to 11 years): 20 ml/kg to 100 ml/kg/24 hours.

Rate of administration:

In continuous treatments, except in cases of severe fluid loss, the infusion rate is normally 40 ml/kg/24 hours in adults.

In pediatric patients, the infusion rate is 5 ml/kg/hour on average, but the value varies with age: 6-8 ml/kg/hour for infants, 4-6 ml/kg/hour for children from 1 to 2 years and a half, and 2-4 ml/kg/hour for school-age children.

Method of administration

Intravenous route

Online doctors for IONOLYTE SOLUTION FOR INFUSION

Discuss questions about IONOLYTE SOLUTION FOR INFUSION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.
Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
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Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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€55
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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50

Frequently Asked Questions

Is a prescription required for IONOLYTE SOLUTION FOR INFUSION?
IONOLYTE SOLUTION FOR INFUSION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in IONOLYTE SOLUTION FOR INFUSION?
The active ingredient in IONOLYTE SOLUTION FOR INFUSION is electrolytes. This information helps identify medicines with the same composition but different brand names.
Who manufactures IONOLYTE SOLUTION FOR INFUSION?
IONOLYTE SOLUTION FOR INFUSION is manufactured by Fresenius Kabi España, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of IONOLYTE SOLUTION FOR INFUSION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether IONOLYTE SOLUTION FOR INFUSION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to IONOLYTE SOLUTION FOR INFUSION?
Other medicines with the same active substance (electrolytes) include SODIUM ACETATE 1M FRESENIUS KABI CONCENTRATE FOR PERFUSION SOLUTION, APIROSERUM SODIUM CHLORIDE 2% SOLUTION FOR INFUSION, APIROSERUM RINGER'S SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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