Bg pattern

ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

ICOMIX 0.28%/ 9.3% Compressed Medical Gas

Carbon Monoxide (CO), Helium (He)

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is ICOMIX and what is it used for
  2. What you need to know before you start using ICOMIX
  3. How to use ICOMIX
  4. Possible side effects
  5. Storage of ICOMIX
  6. Contents of the pack and further information

1. What is ICOMIX and what is it used for

This medicinal product is for diagnostic use of lung function only. ICOMIX should only be used in patients who are able to perform the test, regardless of age.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you start using ICOMIX

Children and Adolescents

This medicinal product should be used with caution in children. Ask your doctor or nurse before using this medicinal product.

Pregnancy and Breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using ICOMIX.

ICOMIX should only be used during pregnancy when absolutely necessary.

ICOMIX can be used during breast-feeding.

3. How to use ICOMIX

ICOMIX is for use only during diagnostic tests of lung function. You should follow the instructions of the medical staff attending you exactly. If in doubt, consult your doctor or nursing staff again.

If the dose of ICOMIX is higher than prescribed

If you have taken too much of the product, you may experience symptoms of low oxygen levels in the blood, such as altered consciousness, headache, dizziness, nausea, vomiting, and blurred vision; chest pain, shortness of breath, weakness, or other vague symptoms.

If you experience any of these symptoms, inform the healthcare staff immediately and stop inhaling ICOMIX.

Safety Information

  • ICOMIX is for medicinal use only.
  • Smoking or igniting flames is not allowed in the room where this product is being used.

If you have any other questions about the use of this medicinal product, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medicines, this medicinal product can cause side effects, although not everybody gets them.

No known side effects have been associated with the use of ICOMIX.

Reporting of Side Effects

If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this package leaflet. You can also report side effects directly through the Spanish Medicines Agency's website: www.notificaRAM.es

By reporting side effects, you can help provide more information on the safety of this medicinal product.

5. Storage of ICOMIX

Keep this medicinal product out of the sight and reach of children.

Store the cylinders in restricted access areas, reserved for medical gases. Do not expose to high temperatures.

In case of fire, if possible, move the cylinders to a safe place. Handle with care. Return used cylinders to the supplier with a minimum residual pressure (5 bar overpressure).

Store and transport the cylinders with the valve closed and with the protective cap in place.

Do not use ICOMIX after the expiry date stated on the cylinder label.

6. Contents of the Pack and Further Information

What ICOMIX contains

The active substances are carbon monoxide (CO) and helium (He).

The other ingredients are nitrogen (N2) and oxygen (O2).

Appearance and Packaging

ICOMIX is a colorless, odorless, and tasteless gas.

Pharmaceutical form: medicinal gas, compressed

The top part (nose) of the cylinders has light green marks (inert gas). The body of the gas cylinder is white (medicinal gas).

Packaging (including materials) and valves:

10-liter aluminum cylinder with closing valve.

20-liter aluminum cylinder with closing valve.

40-liter aluminum cylinder with closing valve.

50-liter aluminum cylinder with closing valve.

Marketing Authorization Holder and Manufacturer

Linde Sverige AB

Rättarvägen 3

169 68 Solna

Sweden.

Manufacturer

Linde Gas AB

Baltzar von Platens gata 4-6

749 47 Enköping

Sweden.

Linde GmbH

Seitnerstr. 70,

82049 Pullach

Germany

With manufacturing plant in:

Linde GmbH, Betriebsstaette Leuna

Spergauer Straße 1a

06237 Leuna

Germany

Linde Gas Therapeutics Benelux B.VDe Keten 7, 5651 JG te EindhovenNetherlands

This medicinal product is authorized in the Member States of the European Union under the following names:

Austria: iCOmix

Belgium: Carbon monoxide 0.28%, Helium 9,3 % Linde

Denmark: Lung test gas CO/He Linde

Finland: Lung test gas CO/He Linde

Germany: iCOmix

Iceland: Lung test gas CO/He Linde

Luxembourg: ICOMIX

Netherlands: ICOMIX

Portugal: Icomix

Spain: ICOMIX

Sweden: Lung test gas CO/He Linde

Date of last revision of this package leaflet:December 2024

Detailed information on this medicinal product is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

The following information is intended for healthcare professionals only:

Safety Instructions

  • Connect only to medical connections.
  • Keep the cylinder clean, dry, and free from grease and oil.
  • Turn off/disconnect the equipment when not in use.
  • In case of fire, turn off/disconnect the equipment.
  • The pressure regulator should be opened slowly and with care.
  • ICOMIX should only be used in well-ventilated areas.
  • When the cylinder is in use, it should be properly secured.
  • This product should not be used with a pressure lower than 5 bar. This residual pressure protects the cylinder from possible contamination.

After use, the cylinder valve should be closed using normal manual pressure. Depressurize the regulator or connector.

Online doctors for ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

Discuss questions about ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (37)
Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

Camera Book a video appointment
€60
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

Camera Book a video appointment
€80
5.0 (181)
Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Camera Book a video appointment
€50
0.0 (0)
Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
€55
0.0 (0)
Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

Camera Book a video appointment
€80

Frequently Asked Questions

Is a prescription required for ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
The active ingredient in ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS is Other diagnostic agents. This information helps identify medicines with the same composition but different brand names.
Who manufactures ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS is manufactured by Linde Sverige Ab. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
Other medicines with the same active substance (Other diagnostic agents) include APULCO ACOMETH 0.3%/0.3%/0.3% MEDICINAL COMPRESSED GAS, APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS, APULCO COHEMAX 0.28%/14% MEDICINAL COMPRESSED GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media