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ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

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Talk to a doctor about this medicine

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

ICOMIX 0.28%/ 9.3% Compressed Medical Gas

Carbon Monoxide (CO), Helium (He)

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is ICOMIX and what is it used for
  2. What you need to know before you start using ICOMIX
  3. How to use ICOMIX
  4. Possible side effects
  5. Storage of ICOMIX
  6. Contents of the pack and further information

1. What is ICOMIX and what is it used for

This medicinal product is for diagnostic use of lung function only. ICOMIX should only be used in patients who are able to perform the test, regardless of age.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you start using ICOMIX

Children and Adolescents

This medicinal product should be used with caution in children. Ask your doctor or nurse before using this medicinal product.

Pregnancy and Breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using ICOMIX.

ICOMIX should only be used during pregnancy when absolutely necessary.

ICOMIX can be used during breast-feeding.

3. How to use ICOMIX

ICOMIX is for use only during diagnostic tests of lung function. You should follow the instructions of the medical staff attending you exactly. If in doubt, consult your doctor or nursing staff again.

If the dose of ICOMIX is higher than prescribed

If you have taken too much of the product, you may experience symptoms of low oxygen levels in the blood, such as altered consciousness, headache, dizziness, nausea, vomiting, and blurred vision; chest pain, shortness of breath, weakness, or other vague symptoms.

If you experience any of these symptoms, inform the healthcare staff immediately and stop inhaling ICOMIX.

Safety Information

  • ICOMIX is for medicinal use only.
  • Smoking or igniting flames is not allowed in the room where this product is being used.

If you have any other questions about the use of this medicinal product, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medicines, this medicinal product can cause side effects, although not everybody gets them.

No known side effects have been associated with the use of ICOMIX.

Reporting of Side Effects

If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this package leaflet. You can also report side effects directly through the Spanish Medicines Agency's website: www.notificaRAM.es

By reporting side effects, you can help provide more information on the safety of this medicinal product.

5. Storage of ICOMIX

Keep this medicinal product out of the sight and reach of children.

Store the cylinders in restricted access areas, reserved for medical gases. Do not expose to high temperatures.

In case of fire, if possible, move the cylinders to a safe place. Handle with care. Return used cylinders to the supplier with a minimum residual pressure (5 bar overpressure).

Store and transport the cylinders with the valve closed and with the protective cap in place.

Do not use ICOMIX after the expiry date stated on the cylinder label.

6. Contents of the Pack and Further Information

What ICOMIX contains

The active substances are carbon monoxide (CO) and helium (He).

The other ingredients are nitrogen (N2) and oxygen (O2).

Appearance and Packaging

ICOMIX is a colorless, odorless, and tasteless gas.

Pharmaceutical form: medicinal gas, compressed

The top part (nose) of the cylinders has light green marks (inert gas). The body of the gas cylinder is white (medicinal gas).

Packaging (including materials) and valves:

10-liter aluminum cylinder with closing valve.

20-liter aluminum cylinder with closing valve.

40-liter aluminum cylinder with closing valve.

50-liter aluminum cylinder with closing valve.

Marketing Authorization Holder and Manufacturer

Linde Sverige AB

Rättarvägen 3

169 68 Solna

Sweden.

Manufacturer

Linde Gas AB

Baltzar von Platens gata 4-6

749 47 Enköping

Sweden.

Linde GmbH

Seitnerstr. 70,

82049 Pullach

Germany

With manufacturing plant in:

Linde GmbH, Betriebsstaette Leuna

Spergauer Straße 1a

06237 Leuna

Germany

Linde Gas Therapeutics Benelux B.VDe Keten 7, 5651 JG te EindhovenNetherlands

This medicinal product is authorized in the Member States of the European Union under the following names:

Austria: iCOmix

Belgium: Carbon monoxide 0.28%, Helium 9,3 % Linde

Denmark: Lung test gas CO/He Linde

Finland: Lung test gas CO/He Linde

Germany: iCOmix

Iceland: Lung test gas CO/He Linde

Luxembourg: ICOMIX

Netherlands: ICOMIX

Portugal: Icomix

Spain: ICOMIX

Sweden: Lung test gas CO/He Linde

Date of last revision of this package leaflet:December 2024

Detailed information on this medicinal product is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).

The following information is intended for healthcare professionals only:

Safety Instructions

  • Connect only to medical connections.
  • Keep the cylinder clean, dry, and free from grease and oil.
  • Turn off/disconnect the equipment when not in use.
  • In case of fire, turn off/disconnect the equipment.
  • The pressure regulator should be opened slowly and with care.
  • ICOMIX should only be used in well-ventilated areas.
  • When the cylinder is in use, it should be properly secured.
  • This product should not be used with a pressure lower than 5 bar. This residual pressure protects the cylinder from possible contamination.

After use, the cylinder valve should be closed using normal manual pressure. Depressurize the regulator or connector.

Online doctors for ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS

Discuss questions about ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
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  • eFAST and critical care transthoracic echocardiography
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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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€58
5.0 (3)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€80
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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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€70
5.0 (764)
Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

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  • Chronic diseases: hypertension, elevated cholesterol, weight management.
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She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
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  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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€55
5.0 (29)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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€60

Frequently Asked Questions

Is a prescription required for ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS is manufactured by Linde Sverige Ab. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ICOMIX 0.28%/9.3% MEDICINAL COMPRESSED GAS?
Other medicines with the same active substance () include APULCO ACOMETH 0.3%/0.3%/0.3% MEDICINAL COMPRESSED GAS, APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS, APULCO COHEMAX 0.28%/14% MEDICINAL COMPRESSED GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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