Skip to main content

HEMICRANEAL 300 mg/100 mg /1 Mg Tablet

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use HEMICRANEAL TABLETS

Contents of the leaflet

  1. Introduction
  2. What Hemicraneal tablets are and what they are used for
  3. What you need to know before you take Hemicraneal tablets
  4. During treatment with Hemicraneal tablets, inform your doctor immediately if:
  5. How to take Hemicraneal tablets
  6. Possible side effects
  7. Storing Hemicraneal tablets
  8. Contents of the pack and further information

Introduction

Package Leaflet: Information for the Patient

Hemicraneal 300 mg/100 mg/1 mg Coated Tablets

Paracetamol/Caffeine/Ergotamine Tartrate

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack and other information:

  1. What Hemicraneal tablets are and what they are used for
  2. What you need to know before you take Hemicraneal tablets
  3. How to take Hemicraneal tablets
  4. Possible side effects
  5. Storing Hemicraneal tablets
  6. Contents of the pack and further information.

.

1. What Hemicraneal tablets are and what they are used for

Hemicraneal tablets belong to a group of medicines called antimigraine medicines.

Hemicraneal tablets are indicated for migraine attacks, equivalent migrainous conditions, and vasomotor headaches.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Hemicraneal tablets

Do not take Hemicraneal tablets

  • If you are allergic (hypersensitive) to the active substances or to any of the other ingredients of this medicine.
  • If you have peripheral circulation disorders, vascular disease that decreases blood flow to the arms and legs (vascular occlusive disease); heart disease due to decreased blood flow to the heart (ischemic heart disease); hypertension; generalized infection (sepsis); kidney failure; liver disease.
  • If you are taking any other medicine listed in the "Use with other medicines" section without consulting your doctor.
  • If you are pregnant or breastfeeding.

Warnings and precautions

During treatment with Hemicraneal tablets, inform your doctor immediately if:

If you have severe diseases, such as severe kidney failure or sepsis (when bacteria and their toxins circulate in the blood, causing damage to organs), or if you have malnutrition, chronic alcoholism, or are also taking flucloxacillin (an antibiotic). A serious disease called metabolic acidosis (an anomaly in the blood and fluids) has been reported in patients in these situations when paracetamol is used at regular doses for a prolonged period or when paracetamol is taken with flucloxacillin. The symptoms of metabolic acidosis may include: severe breathing difficulties with deep and rapid breathing, drowsiness, feeling unwell (nausea) and vomiting.

  • This medicine should only be taken during acute migraine attacks or vascular-type headaches (vasomotor headache) and not as a treatment to prevent their onset.
  • You should avoid prolonged use of this medicine or use at doses higher than recommended, as higher doses than recommended may cause contraction of the arteries, which can lead to cerebral or cardiac disorders (vasospasm), and after prolonged treatments, alterations in the membrane that covers the lungs (pleura), the membrane that covers the intestinal loops (peritoneum), or more rarely, the heart valves.
  • In case of tingling, numbness, or burning sensation in the skin or coldness of hands and feet, you should stop treatment and consult your doctor.
  • You should avoid excessive use of Hemicraneal tablets, as it may worsen and increase the frequency of your headaches.

Use of Hemicraneal in athletes

If you are an athlete, you should know that this medicine contains caffeine, which may result in a positive doping test.

Use of Hemicraneal with other medicines

Tell your doctor or pharmacist if you are using or have recently used any other medicines, including those obtained without a prescription.

Especially if you are being treated with:

  • those medicines that are eliminated by the same route as ergotamine, as it may favor the onset of ergotism, such as: other ergotamine preparations; other medicines for the treatment of migraine, such as sumatriptan, almotriptan, naratriptan; medicines for the treatment of HIV infection, such as amprenavir, nelfinavir, ritonavir, saquinavir, efavirenz; macrolide antibiotics (erythromycin, clarithromycin, and azithromycin); medicines for the treatment of fungal infections, such as ketoconazole, itraconazole, or voriconazole, and sibutramine, which is used for the treatment of obesity.
  • beta-blockers (nadolol, oxprenolol, propanolol, timolol) and dopamine.
  • Chloramphenicol, as it may increase its toxicity due to paracetamol.
  • Flucloxacillin (antibiotic), due to a serious risk of blood and fluid anomaly (called metabolic acidosis) that requires urgent treatment (see section 2).

Pregnancy and breastfeeding

Hemicraneal tablets should not be used during pregnancy and breastfeeding.

Consult your doctor or pharmacist before taking any medicine.

Driving and using machines

It should be taken into account that some symptoms, such as drowsiness, dizziness, and weakness, caused by the migraine crisis itself, may affect the ability to drive or use machines.

Important information about some of the ingredients of Hemicraneal tablets

This medicine may cause allergic reactions because it contains orange yellow S (E-110). It can cause asthma, especially in patients allergic to acetylsalicylic acid.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

3. How to take Hemicraneal tablets

Follow exactly the administration instructions of Hemicraneal tablets indicated by your doctor. In case of doubt, consult your doctor or pharmacist again.

Posology

The recommended dose of Hemicraneal tablets in adult patients is 2 tablets at the onset of the first symptoms of the crisis; if it does not subside, 1 tablet may be administered every hour. Do not exceed 6 tablets in a day, or 10 tablets in a week.

Children: Not recommended in children under 12 years.

If you take more Hemicraneal tablets than you should

In case of overdose or accidental ingestion, go immediately to a medical center or call the Toxicology Information Service (telephone: 915620420), indicating the medicine and the amount ingested. The symptoms can be very serious and usually appear from the third day after ingestion.

The most characteristic symptoms of paracetamol overdose include dizziness, vomiting, loss of appetite, yellowing of the skin (jaundice), and abdominal pain.

Paracetamol overdose is considered to be a single dose of more than 6 g in adults and more than 100 mg per kg of body weight in children. Patients being treated with barbiturates or chronic alcoholics may be more susceptible to the toxicity of a paracetamol overdose.

Treatment consists of gastric aspiration and lavage, oral activated charcoal, intravenous administration of N-acetylcysteine at adequate doses, and, if necessary, hemodialysis. The period in which treatment offers the greatest guarantee of efficacy is within 12 hours after ingestion of the overdose.

Ergotamine may add a picture of peripheral ischemia that should be treated with peripheral vasodilators, local heat, and heparin.

If you forget to take Hemicraneal tablets

Do not take a double dose to make up for forgotten doses.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Hemicraneal tablets can cause side effects, although not everybody gets them:

Frequent(May affect up to 1 in 10 people):

Dizziness

Nausea and vomiting not related to migraine

Abdominal pain

Uncommon(May affect up to 1 in 100 people):

Numbness and tingling of fingers and toes

Bluish discoloration of skin and mucous membranes

Diarrhea

Pain and weakness in arms and legs

Vasoconstriction

Rare(May affect up to 1 in 1,000 people):

Vertigo

Acceleration or slowing of heart rate

Increased blood pressure

Skin rash, facial edema, urticaria

Muscle pain

Headache

Lack of pulse

Breathing difficulties

Hypotension (decreased blood pressure)

Increased levels of liver transaminases (markers of liver function)

Discomfort

Fibrotic changes in heart valves after prolonged treatments

Ergotism (poisoning by ergot alkaloids)

Very rare(May affect up to 1 in 10,000 people):

Myocardial infarction or angina pectoris

Gangrene

Changes in blood cell count, such as leukopenia or neutropenia

Hypoglycemia (decreased blood glucose levels)

Jaundice (yellowing of skin and eyes)

Cloudy urine

Severe skin reactions

Frequency not known(cannot be estimated from the available data):

Retroperitoneal fibrosis after prolonged treatments

Hepatitis after prolonged treatments

Coldness of hands and feet

Pleural fibrosis after prolonged treatments

A serious disease that can make the blood more acidic (called metabolic acidosis) in patients with severe disease using paracetamol (see section 2).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing Hemicraneal tablets

Keep this medicine out of the sight and reach of children.

Store below 25°C.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date is the last day of the month stated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Hemicraneal tablets

  • The active substances are: paracetamol, caffeine, ergotamine tartrate.
  • The other ingredients are: microcrystalline cellulose (E-460), povidone (E-1201), corn starch, magnesium stearate (E-470b), tartaric acid (E-334), quinoline yellow (E-104), orange yellow S (E-110), copovidone, talc (E-553b), titanium dioxide (E-171), macrogol 6,000, hydroxypropyl cellulose (E-464), carnauba wax (E-903), and purified water.

Appearance of the product and pack contents

Hemicraneal tablets are presented as orange-yellow, oval, scored tablets.

The score line is only to facilitate breaking the tablet if you have difficulty swallowing it whole.

Each pack contains 20 tablets.

Marketing authorization holder and manufacturer:

Marketing authorization holder:

Desma Laboratorio Farmacéutico SL

Paseo de la Castellana 121, Escalera Izquierda 3ºB

28046 Madrid,

Tel: +34913238792

Manufacturer:

Laboratorio Farmaceutico S.I.T. Srl.

Via Cavour, 70

27035 Mede (PV) Italy

Date of last revision of this leaflet: February 2025.

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS).

http://www.aemps.gob.es/

Online doctors for HEMICRANEAL TABLETS

Discuss questions about HEMICRANEAL TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

Get HEMICRANEAL TABLETS Prescription Online

1

Fill in a 2-min form

Tell us your symptoms, history, and what medicine you're requesting.

2

Pick a doctor or let us assign

Choose a specialist or we'll match you with the next available doctor.

3

Doctor reviews your case

Usually within 30 minutes. They may ask follow-up questions via chat.

4

Collect from any pharmacy

Electronic prescription sent to your email — valid across Spain.

Frequently Asked Questions

HEMICRANEAL TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in HEMICRANEAL TABLETS is ergotamine, combinations excl. psycholeptics. This information helps identify medicines with the same composition but different brand names.

The average pharmacy price for HEMICRANEAL TABLETS is around 3.59 EUR. Prices may vary depending on the manufacturer and dosage form.

HEMICRANEAL TABLETS is manufactured by Desma Laboratorio Farmaceutico S.L.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether HEMICRANEAL TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy HEMICRANEAL TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (ergotamine, combinations excl. psycholeptics) include CAFERGOT 1 mg/100 mg TABLETS, HEMICRANEAL 400 MG/100 MG /2 MG SUPPOSITORIES, AIMOVIG 140 mg SOLUTION FOR INJECTION IN A PRE-FILLED PEN. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media