Glucocemin 330 mg/ml injectable solution
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How to use GLUCOCEMIN 33% INJECTABLE SOLUTION
Contents of the leaflet
- Introduction
- What is Glucocemin 33% and what is it used for
- What you need to know before you start using Glucocemin 33%
- How to use Glucocemin 33%
- Possible side effects
- Storage of Glucocemin 33%
- Contents of the pack and other information
Introduction
Package Leaflet: Information for the User
Glucocemin 33%
Injectable Solution
Anhydrous glucose, 330 mg/ml
Read all of this leaflet carefully before you start using this medicine
- Keep this leaflet, you may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
- If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
Contents of the package leaflet:
- What is GLUCOCEMIN 33% and what is it used for
- What you need to know before you start using GLUCOCEMIN 33%
- How to use GLUCOCEMIN 33%
- Possible side effects
- Storage of GLUCOCEMIN 33%
- Contents of the pack and other information
1. What is Glucocemin 33% and what is it used for
GLUCOCEMIN 33% belongs to the group of solutions for parenteral nutrition (directly into a vein) intended for the supply of sugar as energy.
GLUCOCEMIN 33% is an injectable solution used:
- in glucose deficit of any cause.
- as an additive for energy supply in parenteral nutrition (feeding directly into a vein) when oral food intake is limited.
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Discuss your symptoms and treatment with a doctor online.
2. What you need to know before you start using Glucocemin 33%
Do not useGLUCOCEMIN 33%
- if you are allergic (hypersensitive) to glucose or any of the other components of GLUCOCEMIN 33%.
- in states of excess glucose in the blood (hyperglycemia).
- if you have excess acid in the body (acidosis).
Be careful with GLUCOCEMIN 33%
Tell your doctor if:
- you have diabetes. It can be used if adequate insulin treatment is initiated beforehand.
- you suffer from kidney or liver failure.
GLUCOCEMIN 33% should not be administered with the same perfusion equipment (equipment used to administer medications directly into the blood), either at the same time, before, or after a blood transfusion, as incompatibilities may occur.
Regular monitoring of blood sugar, electrolyte levels, and water balance should be performed.
Adequate vitamin intake (particularly vitamin B1) should be ensured.
Along with the glucose solution, potassium may be administered to prevent hypokalemia (low potassium levels in the blood) that may occur during parenteral nutrition.
Patients with critical conditions, pain, postoperative stress, infections, burns, nervous system diseases, cardiac, hepatic, and renal diseases, and patients taking medications that increase the effect of vasopressin (a hormone that regulates body fluids), when administered glucocemin 33%, have a certain risk of developing abnormally low sodium levels in the blood (acute hyponatremia) that can lead to brain inflammation (encephalopathy).
Acute hyponatremia can cause acute hyponatremic encephalopathy (brain edema) characterized by headache, nausea, seizures, lethargy, and vomiting. Patients with brain edema are at special risk of suffering severe, irreversible, and potentially fatal brain damage.
Children, women of childbearing age, and patients with severe brain diseases such as meningitis (infection in the membranes surrounding the brain) or brain damage are at risk of severe and potentially fatal brain inflammation caused by a sudden decrease in sodium levels in the blood.
Use in elderly patients
It should be administered with caution in elderly patients, as they may have affected liver and/or kidney function.
Use of other medications
Tell your doctor or pharmacist if you are using or have recently used other medications, including those purchased without a prescription.
Taking some medications at the same time can be hazardous. The use of GLUCOCEMIN 33% with other medications can alter the effectiveness of both treatments.
In particular, it is essential to inform your doctor if you are taking any of the following medications:
- Insulin or oral antidiabetics (biguanides, sulfonylureas): these medications decrease the effect of glucose.
- Corticosteroids (cortisol): due to the risk of increased glucose in the blood or the ability of these medications to retain sodium and water.
- Digitalis glycosides (digoxin): because there is a risk of developing an overdose of these medications.
- Medications that increase the effect of vasopressin and the risk of low sodium levels (hyponatremia):
- Carbamazepine and oxcarbazepine used to treat epilepsy.
- Vincristine and Ifosfamide used to treat cancer.
- Cyclophosphamide to treat cancer and autoimmune diseases.
- Selective serotonin reuptake inhibitors (SSRIs) to treat depression.
- Antipsychotics for mental disorders.
- Opioid analgesics to relieve severe pain.
- Non-steroidal anti-inflammatory medications to relieve mild to moderate pain and treat body inflammation.
- Desmopressin to treat diabetes insipidus (extreme thirst and continuous production of large volumes of diluted urine).
- Oxytocin used during childbirth.
- Vasopressin and terlipressin used to treat "bleeding esophageal varices" (dilated veins in the esophagus caused by liver problems).
- Diuretics (medications that increase the amount of urine excreted).
Use in children
For children over 2 years:
The dose is the same as that recommended for adults.
Newborns and children under 2 years:
For the treatment of hypoglycemia (decrease in blood glucose concentration) in these patients, it is preferable to use a less concentrated glucose solution than GLUCOCEMIN 33%.
Pregnancy and breastfeeding
Consult your doctor or pharmacist before using any medication.
Glucose solutions should be administered with caution in pregnant women. In case of pregnancy, your doctor will decide on the convenience of its use.
Glucose solutions should be administered with special caution in pregnant women during childbirth, especially if administered in combination with oxytocin, due to the risk of hyponatremia.
There is no evidence to suggest that glucose solutions can cause adverse effects in the newborn during breastfeeding. Nevertheless, it is recommended to use them with caution during this period.
3. How to use Glucocemin 33%
This medication will always be administered by healthcare personnel.
Your doctor will decide on the most suitable dose in each case, depending on the patient's condition (age, weight, clinical situation, and metabolic state).
Your doctor will monitor blood sugar, electrolyte levels, and fluid balance before and during treatment, especially in patients with alterations in vasopressin release (a hormone that regulates body fluids) and in patients taking medications that increase the action of vasopressin due to the risk of abnormally low sodium levels in the blood (hyponatremia).
GLUCOCEMIN 33% can become extremely hypotonic after administration due to glucose metabolism in the body.
If you use more GLUCOCEMIN 33% than you should
This is unlikely to happen, as your doctor will determine your daily doses. However, if you receive a larger amount of medication than you should, you may experience water excess (hyperhydration), excess glucose in the blood (hyperglycemia), and alterations in the balance of salts in the blood (hyperosmolarity), which are accompanied by disturbances of consciousness, seizures, and coma.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
In case of overdose or accidental ingestion, consult the Toxicology Information Service (telephone: 91.562 04 20) or consult your doctor or pharmacist. Bring this leaflet with you.
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4. Possible side effects
Like all medications, GLUCOCEMIN 33% can cause side effects, although not everyone will experience them.
Side effects can occur if the solution is administered too quickly or if the amount administered is excessive. In this case, the following may appear:
Excess glucose in the blood (hyperglycemia), glucose elimination in the urine (glucosuria).
The resulting hyperglycemia from too rapid or excessive administration should be carefully monitored in severe cases of diabetes mellitus.
You may develop an imbalance in fluid and mineral levels in your body. You may develop low sodium (hyponatremia), potassium, phosphate, and magnesium levels in the blood, hospital hyponatremia, and hyponatremic encephalopathy.
General disorders and administration site conditions:
Itching, pain, infection, inflammation of the vein wall (phlebitis).
Reporting of side effects
If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report them directly through the Spanish Medicines Monitoring System: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medication.
5. Storage of Glucocemin 33%
Keep this medication out of the sight and reach of children.
No special storage conditions are required.
Do not use GLUCOCEMIN 33% after the expiration date stated on the packaging (after EXP:). The expiration date is the last day of the month indicated.
Do not use GLUCOCEMIN 33% if you notice that the solution is not clear, has particles at the bottom (sedimentation), or if the packaging shows visible signs of deterioration.
Medications should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medications. This will help protect the environment.
6. Contents of the pack and other information
Composition of GLUCOCEMIN 33%:
The active ingredient is: | 1 ml | 10 ml |
Glucose monohydrate | 0.363 g | 3.63 g |
(equivalent to anhydrous glucose) | 0.330 g | 3.30 g |
Energy Value: | 558 kJ/100 ml = 133 kcal/100 ml |
Theoretical Osmolality: | 1832 mOsm/l |
Acidity (pH adjustment to 7.4): | < 1 mmol/l |
pH: | 3.5 – 5.5 |
The other ingredients are: water for injectable preparations.
Appearance of the product and pack contents
GLUCOCEMIN 33% is an injectable solution presented in packs of 20 ampoules of 10 ml of Miniplasco Classic or Miniplasco Connect.
Not all pack sizes may be marketed.
Marketing authorization holder
B|BRAUN
- Braun Medical, S.A.
Ctra. de Terrassa, 121
08191-Rubí (Barcelona)
Spain
Manufacturer
- Braun Melsungen AG
Carl-Braun-Straße 1
34212 Melsungen
Mailing address:
34209 Melsungen
This leaflet was approved in December 2024
Detailed information on this medication is available on the website of the Spanish Agency for Medicines and Health Products.
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This information is intended only for healthcare professionals:
The contents of each pack are for single use. The unused fraction should be discarded.
The solution should be visually inspected before use. The solution must be transparent, not contain precipitates, and the packaging must be intact. Do not administer otherwise.
Do not administer intramuscularly.
GLUCOCEMIN 33% should be administered by slow intravenous injection or as an additive to another perfusion solution.
These solutions should not be administered through the same perfusion equipment used, being used, or to be used for blood administration, as pseudoagglutination may occur.
In critically ill patients, the administration rate should not exceed 6 mg of glucose per kilogram of body weight per minute. Only in exceptional cases, the administration rate could reach 9 mg of glucose per kilogram of body weight per minute.
Duration of use
The duration of administration can be as long as necessary.
Disposal of unused medication and all materials that have come into contact with it will be carried out in accordance with local regulations.
Illustrative image - Country of registration
- Dosage formINJECTABLE, 330 mg/ml
- ATC codeB05BA03
- Active substance
- Prescription requiredYes
- Manufacturer
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to GLUCOCEMIN 33% INJECTABLE SOLUTION
DEXTROSE FRESENIUS KABI 50% SOLUTION FOR INFUSIONIllustrative imageDosage form: INJECTABLE INFUSION, 50 g glucoseActive substance: carbohydratesManufacturer: Fresenius Kabi España, S.A.U.Prescription requiredFREEFLEX GLUCOSA 10% SOLUTION FOR INFUSIONIllustrative imageDosage form: INJECTABLE PERFUSION, 11 gActive substance: carbohydratesManufacturer: Fresenius Kabi España, S.A.U.Prescription requiredFREEFLEX GLUCOSA 5% SOLUTION FOR INFUSIONIllustrative imageDosage form: INJECTABLE INFUSION, Glucose Monohydrate 5.5 gActive substance: carbohydratesManufacturer: Fresenius Kabi España, S.A.U.Prescription required
Online doctors for GLUCOCEMIN 33% INJECTABLE SOLUTION
Discuss questions about GLUCOCEMIN 33% INJECTABLE SOLUTION, including use, safety considerations and whether a prescription is appropriate, subject to medical assessment and local regulations.
Frequently Asked Questions
GLUCOCEMIN 33% INJECTABLE SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
The active ingredient in GLUCOCEMIN 33% INJECTABLE SOLUTION is carbohydrates. This information helps identify medicines with the same composition but different brand names.
GLUCOCEMIN 33% INJECTABLE SOLUTION is manufactured by B Braun Medical S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Doctors such as Family doctors, Cardiologists, Nephrologists, Hematologists, General surgeons, General medicine doctors, Phlebologists may assess whether GLUCOCEMIN 33% INJECTABLE SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
The prescription is issued by a doctor after assessing your health. In Spain, GLUCOCEMIN 33% INJECTABLE SOLUTION is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.
To request an assessment, you can use Oladoctor:
Other medicines with the same active substance (carbohydrates) include DEXTROSE FRESENIUS KABI 50% SOLUTION FOR INFUSION, FREEFLEX GLUCOSA 10% SOLUTION FOR INFUSION, FREEFLEX GLUCOSA 5% SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
