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Givlaari 189 mg/ml injectable solution

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Prescription request online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience
Licence no. 464628925

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use GIVLAARI 189 mg/mL Injectable Solution

Contents of the leaflet

  1. Introduction
  2. What is Givlaari and what is it used for
  3. What you need to know before you are given Givlaari
  4. How to use Givlaari
  5. Possible side effects
  6. Storage of Givlaari
  7. Contents of the pack and other information

Introduction

Package Leaflet: Information for the User

Givlaari 189 mg/ml Solution for Injection

givosiran

Read all of this leaflet carefully before this medicine is administered to you because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or nurse.
  • If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Givlaari and what is it used for
  2. What you need to know before you are given Givlaari
  3. How to use Givlaari
  4. Possible side effects
  5. Storage of Givlaari
  6. Contents of the pack and other information

1. What is Givlaari and what is it used for

What is Givlaari

Givlaari contains the active substance givosiran.

What Givlaari is used for

Givlaari is used to treat acute hepatic porphyria in adults and adolescents from 12 years of age.

What is acute hepatic porphyria

Acute hepatic porphyria is a rare and inherited disease. It is due to a defect in one of the proteins that make up a molecule called heme produced in the liver. Because there is a problem with one of the proteins that make up heme, the substances used to produce it, namely delta-aminolevulinic acid (ALA) and porphobilinogen (PBG), accumulate. An excess of ALA and PBG can cause nerve damage and lead to crises of pain, nausea, muscle weakness, and changes in mental function. Some people with acute hepatic porphyria may also experience symptoms such as pain and nausea between crises. Long-term complications observed in people with acute hepatic porphyria include hypertension, chronic kidney failure, and liver disease.

How Givlaari works

The medicine works by reducing the amount of an enzyme called "ALAS1", which controls the amount of ALA and PBG produced by the liver. By reducing the amount of ALAS1, the liver produces less ALA and PBG. This may help reduce the effects of the disease.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you are given Givlaari

Givlaari must not be given to you:

  • if you have ever had a severe allergic reaction to givosiran or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Talk to your doctor or nurse before you are given Givlaari.

Severe allergic reaction

  • Tell your doctor or nurse immediately if you start to experience signs of a severe allergic reaction. The signs are mentioned in "Serious side effects" in section 4.
  • If you have a severe allergic reaction, your doctor or nurse will stop using the medicine immediately and you may need to take other medicines to control the symptoms.

Liver problems

Using this medicine may affect your liver. You will have blood tests to check your liver function before starting treatment with Givlaari and these will be repeated periodically during treatment. If these tests show abnormal results, your doctor or nurse will decide whether treatment should be temporarily interrupted or permanently stopped. Abnormalities have been observed in the test results of some patients treated with this medicine, mainly between 3 and 5 months after starting treatment.

Kidney problems

Using this medicine may affect your kidneys, especially if you have already been diagnosed with kidney problems. Your doctor will check that your kidneys are working properly while you are taking this medicine, especially if you already have kidney problems.

Homocysteine level tests

While you are taking this medicine, blood tests may show an increase in homocysteine, a type of amino acid, compared to your homocysteine levels before starting treatment. Your doctor will check your homocysteine levels in the blood before and during treatment. If your homocysteine levels are high, your doctor may give you treatment to reduce homocysteine.

Children

This medicine must not be used in children under 12 years of age because it has not been studied in this age group.

Other medicines and Givlaari

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

When using certain medicines, this medicine may prolong or increase their effect or change their side effects.

Pregnancy

If you are pregnant, think you may be pregnant, or plan to become pregnant, consult your doctor or nurse before using this medicine.

Breast-feeding

Animal studies show that this medicine can pass into breast milk. If you are breast-feeding, consult your doctor before using this medicine. Your doctor will help you decide whether to stop breast-feeding or stop treatment with Givlaari after considering the benefit of breast-feeding to your child and the benefit of treatment to you.

Driving and using machines

This medicine is not expected to affect your ability to drive or use machines.

Givlaari contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per ml, which is essentially "sodium-free".

3. How to use Givlaari

How much Givlaari is given

Your doctor will decide how much medicine you should be given. The amount will depend on your body weight.

  • The recommended dose is 2.5 milligrams per kilogram of body weight
  • The medicine will be given to you once a month (every 4 weeks)
  • If liver damage is observed in the blood test results, your doctor may interrupt treatment with Givlaari or stop it permanently. Your doctor may consider restarting it at a lower dose.

How to use Givlaari

A doctor or nurse will give you this medicine once a month. It is given by injection under the skin (subcutaneously) in the stomach area (abdominal) or, in some cases, in the arm or thigh. The injection site will be alternated. If the dose is more than 1 ml, more than one vial may be needed and more than one subcutaneous injection may be required.

If you are given too much Givlaari

In the unlikely event that your doctor or nurse gives you too much (overdose), you will be monitored for side effects.

If you miss a dose of Givlaari

If you miss an appointment for an injection, talk to your doctor or nurse as soon as possible.

If you have any other questions about using this medicine, ask your doctor or nurse.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Serious side effects

Severe allergic reactions (uncommon: may affect up to 1 in 100 people)

Tell your doctor or nurse immediately if you experience any of the following signs of a severe allergic reaction (anaphylactic reaction); the injection will be stopped and you may need to take other medicines to treat the reaction:

  • swelling: mainly of the lips, tongue, or throat, which may make swallowing or breathing difficult
  • breathing problems or wheezing
  • feeling dizzy or fainting
  • rash, hives
  • itching

Other side effects

Tell your doctor or nurse if you notice any of the following side effects:

Very common:may affect more than 1 in 10 people

  • Nausea
  • Blood tests showing increased transaminases (liver enzymes), which are a sign of possible liver inflammation
  • Skin rash, including red, dry, itchy skin, eczema, or hives
  • Blood tests showing increased creatinine, a substance that is removed from the body by the kidneys, or decreased glomerular filtration rate (signs of possible kidney damage)
  • Redness, pain, itching, or swelling at the injection site (injection site reaction)
  • Feeling tired

Common:may affect up to 1 in 10 people

  • A type of allergic reaction (hypersensitivity): with symptoms such as hives, skin rash, eye, mouth, or face swelling, difficulty breathing, itching.
  • Pancreatitis (inflammation of the pancreas).
  • Blood tests showing increased homocysteine (a type of amino acid).

Reporting of side effects

If you experience any side effects, talk to your doctor or nurse, even if they are not listed in this leaflet. You can also report side effects directly via the national reporting system listed in the contact information for your country. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Givlaari

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP.

The expiry date is the last day of the month stated.

This medicine is for single use only. Once the product has been opened, use it immediately.

Do not store above 25°C.

Keep the vial in the outer packaging to protect it from light.

Medicines should not be disposed of via wastewater or household waste. Your doctor or nurse will dispose of any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

What Givlaari contains

  • The active substance is givosiran.
  • Each ml contains givosiran sodium equivalent to 189 mg of givosiran.
  • The other ingredients are sodium hydroxide, phosphoric acid, and water for injections. See section 2 "Givlaari contains sodium".

Appearance and packaging

This medicine is a clear, colorless to yellow solution for injection.

Each pack contains one vial of 1 ml solution for injection.

Marketing authorisation holder and manufacturer

Alnylam Netherlands B.V.

Antonio Vivaldistraat 150

1083 HP Amsterdam

Netherlands

For further information about this medicine, contact the local representative of the marketing authorisation holder:

Belgium/België/Belgien

Alnylam Netherlands B.V.

Tel: 0800 81 443 (+32 234 208 71)

[email protected]

Contact information of Genesis Pharma Bulgaria Eood with address, phone number, and email

Luxembourg/Luxemburg

Alnylam Netherlands B.V.

Tel: 80085235 (+352 203 014 48)

[email protected]

Malta

Genesis Pharma (Cyprus) Ltd

Tel: +357 22765715

[email protected]

Czech Republic

Alnylam Czech s.r.o.

Tel: 800 050 450 (+420 234 092 195)

[email protected]

Netherlands

Alnylam Netherlands B.V.

Tel: 08002820025 (+31 203697861)

[email protected]

Denmark

Alnylam Sweden AB

Tel: 433 105 15 (+45 787 453 01)

[email protected]

Norway

Alnylam Sweden AB

Tel: 800 544 00 (+472 1405 657)

[email protected]

Germany

Alnylam Germany GmbH

Tel: 08002569526 (+49 8920190112)

[email protected]

Austria

Alnylam Austria GmbH

Tel: 0800070339 (+43 720 778 072)

[email protected]

Greece

ΓΕΝΕΣΙΣ ΦΑΡΜΑ Α.Ε.

Tel: +30 210 87 71 500

[email protected]

Portugal

Alnylam Portugal

Tel: 707201512 (+351 707502642)

[email protected]

Spain

Alnylam Pharmaceuticals Spain SL

Tel: 900810212 (+34 910603753)

[email protected]

Romania

Genesis Biopharma Romania SRL

Tel: +40 21 403 4074

[email protected]

France

Alnylam France SAS

Tel: 0805542656 (+33 187650921)

[email protected]

Slovenia

Genesis Biopharma SL d.o.o.

Tel: +386 1 292 70 90

[email protected]

Croatia

Genesis Pharma Adriatic d.o.o.

Tel: +385 1 5530 011

[email protected]

Finland

Alnylam Sweden AB

Tel: 0800 417 452 (+358 942 727 020)

[email protected]

Ireland

Alnylam Netherlands B.V.

Tel: 1800 924260 (+353 818 8822137)

[email protected]

Sweden

Alnylam Sweden AB

Tel: 020109162 (+46 842002641)

[email protected]

Italy

Alnylam Italy S.r.l.

Tel: 800 90 25 37 (+39 02 89 73 22 91)

[email protected]

Estonia, Iceland, Latvia, Lithuania, Hungary, Poland, Slovakia

Alnylam Netherlands B.V.

Tel: +31 20 369 7861

[email protected]

Cyprus

Genesis Pharma (Cyprus) Ltd

Tel: +357 22765715

[email protected]

Date of last revision of this leaflet 11/2024

Other sources of information

Detailed information on this medicine is available on the European Medicines Agency website: http://www.ema.europa.eu.

<------------------------------------------------------------------------------------------------------------------

This information is intended only for healthcare professionals:

Instructions for use

For subcutaneous use only.

  • Gather the materials that are not included in the pack and are necessary for administration; these include a sterile syringe (1 ml or 3 ml) with a 21 G (or larger) needle, a 25 G or 27 G needle, and a sharps container.
  • Calculate the volume of Givlaari needed based on the recommended dose according to weight. If the dose is more than 1 ml, more than one vial may be needed and more than one subcutaneous injection may be required. The maximum acceptable volume for each individual injection is 1.5 ml.
  • To withdraw Givlaari, hold the vial upright or tilt it slightly and ensure that the flat edge of the needle is pointing downwards.
  • Withdraw the indicated injection volume with the 21 G (or larger) needle.
  • Divide doses that require a volume greater than 1.5 ml into equal parts in multiple syringes; each injection should contain approximately the same volume.
  • Point the needle and syringe upwards and gently tap the syringe to move any air bubbles to the top. Once the air bubbles are at the top, gently push the plunger to expel the air bubbles from the syringe. Check that the amount of medicine in the syringe is still correct.
  • Once the dose is prepared and in the administration syringe, replace the 21 G (or larger) needle with a 25 G or 27 G needle.
  • Note: Do not put the medicine into the 25 G or 27 G needle.
  • The injection can be given in the abdomen or, if necessary, in the back or side of the arm or in the thighs. Consider alternating injection sites. The medicine must not be given in scar tissue or on red, inflamed, or swollen surfaces.
  • Note: When giving subcutaneous injections in the abdomen, avoid a circle of 5.0 cm in diameter around the navel.
  • Clean the surface where you want to give the injection with an alcohol swab and wait for the surface to dry completely.
  • Make sure to use the correct injection technique. Do not give the injection into a vein or muscle.
  • Pinch and lift the skin at the selected injection site. Insert the needle at a right angle (90 degrees) to give the injection just under the skin. In patients with little subcutaneous tissue or if the needle length is more than 2.5 cm, the needle should be inserted at a 45-degree angle.
  • Do not press the plunger while the needle is penetrating the skin. Once the needle is inserted into the skin, release the pinched skin and administer the dose slowly and steadily. After the medicine has been given, count to at least 5 before removing the needle from the skin. Gently press a cotton ball or swab over the injection site as needed. Do not replace the needle cap.
  • Note: Do not aspirate after inserting the needle to avoid damaging tissue, causing hematomas, and bruising.
  • If more than one injection is needed for a single dose of Givlaari, the injection sites should be at least 2 cm apart from previous injection sites.
  • Use the vial only once. After injecting the dose, discard any unused medicine in the vial according to local regulations.
  • Use syringes, transfer needles, and injection needles only once. Discard used needles and syringes according to local regulations.

Online doctors for GIVLAARI 189 mg/mL Injectable Solution

Discuss questions about GIVLAARI 189 mg/mL Injectable Solution, including use, safety considerations and whether a prescription is appropriate, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience
Licence no. 464628925

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience
Licence no. 35/35/09707

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64

Frequently Asked Questions

GIVLAARI 189 mg/mL Injectable Solution requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in GIVLAARI 189 mg/mL Injectable Solution is givosiran. This information helps identify medicines with the same composition but different brand names.

GIVLAARI 189 mg/mL Injectable Solution is manufactured by Alnylam Netherlands B.V.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether GIVLAARI 189 mg/mL Injectable Solution is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

The prescription is issued by a doctor after assessing your health. In Spain, GIVLAARI 189 mg/mL Injectable Solution is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.

To request an assessment, you can use Oladoctor:

Other medicines with the same active substance (givosiran) include AMMONAPS 500 mg TABLETS, AMMONAPS 940 mg/g GRANULES, CERDELGA 84 mg HARD CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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