Ducressa 1 mg/ml + 5 mg/ml colirio solution
Prescription review online
A doctor will review your case and decide whether a prescription is medically appropriate.
Talk to a doctor about this medicine
Discuss your symptoms and possible next steps in a quick online consultation.
How to use DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION
Contents of the leaflet
- Introduction
- What Ducressa is and what it is used for
- What you need to know before you use Ducressa
- How to use Ducressa
- Possible side effects
- How to store Ducressa
- Contents of the pack and other information
Introduction
Package Leaflet: Information for the User
Ducressa 1mg/ml + 5mg/ml eye drops solution
dexamethasone / levofloxacin
Read the package leaflet carefully before you start using this medicine because it contains important information for you.
- Keep this package leaflet, you may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
- If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
What is in this package leaflet:
- What Ducressa is and what it is used for
- What you need to know before you use Ducressa
- How to use Ducressa
- Possible side effects
- How to store Ducressa
- Contents of the pack and other information
1. What Ducressa is and what it is used for
What kind of medicine is it and how does it work
Ducressa is an eye drop solution that contains levofloxacin and dexamethasone.
Levofloxacin is an antibiotic of the fluoroquinolone type (sometimes abbreviated to quinolones). It works by killing certain types of bacteria that can cause infections.
Dexamethasone is an anti-inflammatory corticosteroid (i.e., it makes signs and symptoms such as pain, heat, inflammation, and redness disappear).
Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or the common cold. It is important that you follow the instructions regarding the dose, administration interval, and treatment duration indicated by your doctor. Do not store or reuse this medicine. If you have any leftover antibiotic after finishing the treatment, return it to the pharmacy for proper disposal. Do not throw away medicines via wastewater or household waste. |
What this medicine is used for
Ducressa is used to prevent and treat inflammation and potential eye infections after cataract surgery in adults.
Not sure if this medicine is right for you?
Discuss your symptoms and treatment with a doctor online.
2. What you need to know before you use Ducressa
Do not use Ducressa
- if you are allergic to levofloxacin (or other quinolones) or dexamethasone (or other corticosteroids) or any of the other ingredients of this medicine (listed in section 6).
- if you have an eye infection that is not being treated with any medicine, including viral infections (such as herpes simplex keratitis or chickenpox), fungal infections, and tuberculosis of the eye.
If your eye produces a sticky discharge, or if your eye is red and has not been treated by a doctor, you may have an infection.
Warnings and precautions
Consult your doctor before starting to use Ducressa:
- if you are using any other antibiotic treatment, including oral antibiotics. As with any other anti-infective agent, prolonged use may lead to antibiotic resistance, resulting in an overgrowth of pathogenic microorganisms.
- if you have ocular hypertension or have had it after using an ocular corticosteroid, you are at risk of having it again if you use Ducressa. If you have ocular hypertension, inform your doctor.
- if you have glaucoma.
- if you have visual disturbances or blurred vision.
- if you are using non-steroidal anti-inflammatory drugs (NSAIDs), see section "Other medicines and Ducressa".
- if you have a disorder that causes thinning of the eye tissues, as prolonged use of corticosteroid treatments may cause further thinning and perforation.
- if you have diabetes.
Important information if you wear contact lenses
After cataract surgery, you should not wear contact lenses during treatment with Ducressa.
Children and adolescents
Ducressa is not recommended for use in children and adolescents under 18 years of age due to the lack of safety and efficacy data in this age group.
Other medicines and Ducressa
Tell your doctor or pharmacist:
- if you are using, have recently used, or might use any other medicine, including those bought without a prescription.
- if you are using any other type of eye drops or ointment before starting to use Ducressa (see section 3, How to use Ducressa).
- if you are using ocular NSAIDs (to treat pain and inflammation in the eye), such as ketorolac, diclofenac, bromfenac, and nepafenac. The simultaneous use of ocular corticosteroids and ocular NSAIDs may increase the risk of eye healing problems.
- if you are using ritonavir or cobicistat (used to treat HIV), as these may increase the amount of dexamethasone in the blood.
- if you are using probenecid (to treat gout), cimetidine (to treat stomach ulcers), and cyclosporin (to prevent transplant rejection), as these medicines may alter the absorption and metabolism of levofloxacin.
Pregnancy and breastfeeding
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine. Ducressa should not be used during pregnancy or breastfeeding.
Driving and using machines
If you experience temporary blurred vision after using this medicine, do not drive or use machines until your vision is clear.
Ducressa contains phosphate buffer
This medicine contains 4.01 mg of phosphates per ml, which corresponds to 0.12 mg per drop. If you have severe corneal damage, treatment with phosphates, in very rare cases, may cause blurred vision due to calcium accumulation. Talk to your doctor, who may prescribe a phosphate-free treatment.
Ducressa contains benzalkonium chloride
This medicine contains 0.05 mg of benzalkonium chloride per ml, which corresponds to 0.0015 mg per drop.
Benzalkonium chloride may cause eye irritation, especially if you have dry eye or other corneal diseases. Consult your doctor if you feel any unusual sensation, itching, or pain in the eye after using this medicine.
3. How to use Ducressa
Follow the instructions for administering this medicine exactly as indicated by your doctor or pharmacist. If you are unsure, consult your doctor or pharmacist again.
The recommended dose is 1 drop in the affected eye every 6 hours. The maximum dose is 4 drops per day. The usual treatment with Ducressa lasts 7 days, which may be followed by an additional 7 days with a corticosteroid eye drop if your doctor considers it necessary.
Your doctor will inform you about the duration of treatment.
If you are using any other eye medicine, wait at least 15 minutes between administering one eye drop and another. Ocular ointments should be used last.
Method of administration:
If possible, ask someone to apply the eye drops for you. Before they do, ask them to read these instructions with you.
- Wash your hands carefully (illustration 1).
- Open the bottle. Remove the ring that separates from the cap when opening the bottle for the first time.
Be careful not to let the tip of the dropper bottle come into contact with the eye, the surrounding skin, or your fingers.
- Unscrew the cap from the bottle. Hold the bottle upside down between your thumb and other fingers.
- Move the lower eyelid down with one finger until a space is created between the eyelid and the eye. This is where you will place the drop (illustration 2).
- Tilt your head back, bring the tip of the bottle close to the eye, and gently squeeze the bottle until a drop falls into the eye (illustration 3). Please note that from the moment you squeeze the bottle until the drop falls, a few seconds may pass. Do not squeeze the bottle too hard.
- After using Ducressa, press the inner corner of your eye, next to your nose, with your finger. This will help prevent the medicine from reaching other parts of your body (illustration 4).
If the drop does not fall into the eye, try again. Close the bottle tightly with the cap immediately after use.
If you use more Ducressa than you should
If you use more of this medicine than you should, you can rinse it off with warm water.
In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone: 91 562 04 20.
If you forget to use Ducressa
If you forget to use this medicine, do not worry, just apply it as soon as possible. Do not apply a double dose to make up for forgotten doses.
If you stop using Ducressa
If you stop using this medicine before the indicated time, inform your doctor. If you have any further questions about the use of this medicine, ask your doctor or pharmacist.
Started taking the medicine and have questions?
Discuss your symptoms and treatment with a doctor online.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Most side effects are not serious and only affect the eye.
- In very rare cases, this medicine may cause severe allergic reactions (anaphylactic reactions), accompanied by inflammation and constriction of the throat, as well as breathing difficulties.
- If you experience any of these symptoms, stop using Ducressa and contact your doctor immediately.
- There have been cases of tendon inflammation and rupture in people receiving fluoroquinolones orally or intravenously, especially in older patients and those treated simultaneously with corticosteroids. Stop using Ducressa if you experience pain or inflammation of the tendons (tendinitis).
You may also experience the following effects in the eye(s):
Very common(may affect more than 1 in 10 people):
- high pressure in the eye.
Common(may affect up to 1 in 10 people):
- discomfort, itching, or irritation, burning, stinging in the eye
- blurred or decreased vision
- eye discharge.
Uncommon(may affect up to 1 in 100 people):
- delayed corneal healing
- eye infections
- abnormal sensation in the eye
- increased tearing
- dry and tired eyes
- eye pain
- increased visual clarity
- inflammation or redness (red eyes) of the front coating of the eye (the conjunctiva)
- inflammation or redness of the eyelid
- sensitivity to light
- sticky eyelids.
Rare(may affect up to 1 in 1,000 people):
- increased pupil size
- drooping eyelids
- calcium accumulation on the surface of the eye (corneal calcification)
- tearing and gritty sensation in the eye (crystalline keratopathy)
- change in the thickness of the eye surface
- ulcer on the surface of the eye
- small holes in the surface of the eye (corneal perforation)
- inflammation of the eye surface (corneal edema)
- inflammation of the eye that causes pain and redness (uveitis).
You may also experience effects in other parts of the body, including:
Uncommon(may affect up to 1 in 100 people):
- headache
- altered sense of taste
- itching
- nasal congestion or runny nose.
Rare(may affect up to 1 in 1,000 people):
- allergic reactions, such as skin rash.
Very rare(may affect up to 1 in 10,000 people):
- facial inflammation.
Not known
- Reduced function of the adrenal gland, which may be perceived as low blood sugar, dehydration, weight loss, and confusion.
- Hormonal problems: excessive growth of body hair (especially in women), weakness and muscle wasting, purple striae on the skin, increased blood pressure, irregular or absent menstrual periods, changes in protein and calcium levels in the body, delayed growth in children and adolescents, and swelling and weight gain of the body and face (called Cushing's syndrome).
Reporting of side effects
If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.
5. How to store Ducressa
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label of the bottle and the carton, after "EXP". The expiry date is the last day of the month shown.
Do not use this medicine if you notice that the plastic ring around the cap and neck is missing or broken before starting a new bottle.
Keep the bottle tightly closed. To avoid infections, you should discard the bottle 28 days after opening it for the first time and use a new bottle.
This medicine does not require any special storage conditions.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.
6. Contents of the pack and other information
What Ducressa contains
- The active substances are levofloxacin in the form of hemihydrate and dexamethasone in the form of sodium phosphate. Each milliliter of solution contains 5 mg of levofloxacin and 1 mg of dexamethasone.
- The other excipients are sodium dihydrogen phosphate monohydrate, disodium hydrogen phosphate dodecahydrate, sodium citrate, benzalkonium chloride, sodium hydroxide/hydrochloric acid (for pH adjustment), and water for injections.
Appearance and packaging
Ducressa is a clear, yellowish-green solution, practically free of particles. The expelled drops appear transparent and colorless. It is supplied in a carton containing a 5 ml white plastic bottle with a white dropper. The plastic bottle is closed with a screw cap.
Marketing authorisation holder
Santen Oy
Niittyhaankatu 20
33720 Tampere
Finland
Manufacturer responsible for batch release
Santen Oy
Kelloportinkatu 1
33100 Tampere
Finland
You can obtain further information on this medicine from the local representative of the marketing authorisation holder:
Santen Pharmaceutical Spain, S.L.
Acanto, 22, 7th floor
28045 Madrid
Spain
Tel.: 91 414 24 85
Date of last revision of this leaflet: June 2022
Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) (http://www.aemps.gob.es/).
- Country of registration
- Dosage formEYEDROP, 1 mg/ml + 5 mg/ml
- ATC codeS01CA01
- Average pharmacy price8.62 EUR
- Active substance
- Prescription requiredYes
- Manufacturer
- CompositionCLORURO DE BENZALCONIO SOLUCION (0,1 mg/ml mg), DIHIDROGENO FOSFATO DE SODIO (1,47 mg/ml mg), HIDROGENOFOSFATO DISODICO DODECAHIDRATADO (10 mg/ml mg), CITRATO DE SODIO (E-331) (21 mg/ml mg), ACIDO CLORHIDRICO/HIDROXIDO DE SODIO (csp 7.2 pH pH mg), HIDROXIDO DE SODIO (E 524) (cs pH mg)
- This information is for reference only and does not constitute medical advice. Always consult a doctor before taking any medication. Oladoctor is not responsible for medical decisions based on this content.
- Alternatives to DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTIONDosage form: EYEDROP, -Active substance: dexamethasone and antiinfectivesManufacturer: Novartis Farmaceutica S.A.Prescription requiredDosage form: EYEDROP, 3 mg/ml + 1 mg/mlActive substance: dexamethasone and antiinfectivesManufacturer: Sifi S.P.A.Prescription requiredDosage form: EYEDROP, 3mg/ml + 1mg/mlActive substance: dexamethasone and antiinfectivesManufacturer: Sifi S.P.A.Prescription required
Online doctors for DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION
Discuss questions about DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.
Frequently Asked Questions
DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
The active ingredient in DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION is dexamethasone and antiinfectives. This information helps identify medicines with the same composition but different brand names.
The average pharmacy price for DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION is around 8.62 EUR. Prices may vary depending on the manufacturer and dosage form.
DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION is manufactured by Santen Oy. Pharmacy brands and packaging may differ depending on the distributor.
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
The prescription is issued by a doctor after assessing your health. In Spain, DUCRESSA 1 mg/ml + 5 mg/ml EYE DROPS SOLUTION is then dispensed in pharmacies with that prescription. An online consultation does not guarantee that a prescription will be issued: the decision always rests with the doctor.
To request a review, you can use Oladoctor:
Other medicines with the same active substance (dexamethasone and antiinfectives) include MAXITROL 3,500 IU/mL + 6,000 IU/mL + 1 mg/mL EYE DROPS, SUSPENSION, NETDEX 3 mg/mL + 1 mg/mL Eye Drops in Single Dose Containers, NETDEX 3 mg/mL + 1 mg/mL EYE DROPS SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
