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DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS

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5.0 (198)
Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Ditralia 25000 IUorodispersible films

colecalciferol (vitamin D3)

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Ditralia and what is it used for
  2. What you need to know before you take Ditralia
  3. How to take Ditralia
  4. Possible side effects
  5. Storing Ditralia
  6. Contents of the pack and other information

1. What is Ditralia and what is it used for

Ditralia contains colecalciferol (vitamin D3). The main function of vitamin D is to ensure proper intestinal absorption of calcium and to promote adequate mineralization of bones.

Ditralia is indicated for the initial treatment of clinically relevant vitamin D deficiency in adults.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Ditralia

Do not take Ditralia

  • if you are allergic to colecalciferol or any of the other ingredients of this medicine (listed in section 6)
  • if you have a particular sensitivity to vitamin D (tissue damage in various organs caused by vitamin D overdose) (hypervitaminosis D)
  • if you have high levels of calcium in the blood
  • if you have high levels of calcium in the urine, especially if you have kidney stones
  • if you have calcium deposits in the kidneys (nephrocalcinosis)
  • if you have severely reduced kidney function (severe renal insufficiency)

If you are in any of the above situations, consult your doctor or pharmacist before taking Ditralia.

Warnings and precautions

Consult your doctor or pharmacist before taking Ditralia.

Tell your doctor if you are taking other products that contain vitamin D, such as fortified foods and milk, as vitamin D accumulates in the body and an overdose can cause toxic effects. Ditralia should be used with caution in immobilized patients.

Therefore, it is important not to exceed the recommended dose.

Consult your doctor before taking Ditralia:

  • if you have a high tendency to form kidney stones
  • if you have a parathyroid hormone imbalance (pseudo-hypoparathyroidism)

If you have any of the following conditions, your doctor will monitor your calcium or phosphate levels in the blood, or your calcium levels in the urine:

  • if you have kidney problems
  • if you suffer from "sarcoidosis", an immune system disease that can affect the liver, lungs, skin, or lymph nodes
  • if you are an elderly person being treated with glycosides or diuretics
  • if you are immobilized

Children and adolescents

This medicine is not recommended for children and adolescents under 18 years of age.

Other medicines and Ditralia

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including those obtained without a prescription.

In particular, consult your doctor if you are taking any of the following medicines:

  • thiazide diuretics: your calcium levels in the blood will be regularly monitored
  • corticosteroids ("steroids", e.g., prednisolone or dexamethasone): your vitamin D dose may need to be increased
  • cholestyramine (a medicine to reduce cholesterol) or laxatives (e.g., paraffin oil): reduce vitamin D absorption
  • heart medicines (cardiac glycosides): you will be under medical supervision and your ECG and calcium levels in the blood may be monitored
  • anticonvulsants (for the treatment of epilepsy; e.g., phenytoin), sleeping medicines (e.g., hydantoin, barbiturics), or primidone: reduce the effects of vitamin D
  • rifampicin, isoniazid (antibiotics): may reduce the effectiveness of vitamin D
  • actinomycin (a medicine used to treat some types of cancer) and antifungal agents derived from imidazole (e.g., clotrimazole and ketoconazole, medicines used to treat fungal infections): may reduce the effectiveness of vitamin D
  • products containing high doses of calcium: increase the risk of high calcium levels in the blood
  • products containing magnesium (e.g., antacids): should not be used during treatment with vitamin D due to the risk of high magnesium levels
  • products containing high doses of phosphorus: concomitant use with vitamin D may increase the risk of high phosphate levels in the blood
  • orlistat (a medicine used to treat obesity, including weight loss): may reduce vitamin D absorption. There should be a 2-hour interval (before and after) between the administration of vitamin D and orlistat.

Taking Ditralia with food and drinks

See section 3 "How to take Ditralia".

Pregnancy, breastfeeding, and fertility

During pregnancy and breastfeeding, high doses of this product should not be used, but lower doses. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking vitamin D. Vitamin D3 passes into breast milk. This should be taken into account when administering additional vitamin D to the infant. There are no data on the effects of vitamin D3 on fertility. However, it is not expected that normal levels of vitamin D will have negative effects on fertility.

Driving and using machines

Ditralia has no or negligible influence on the ability to drive and use machines.

Ditralia contains orange yellow:

Orange yellow (E110), which may cause allergic reactions.

3. How to take Ditralia

Follow exactly the administration instructions of this medicine given by your doctor. If you are not sure, ask your doctor or pharmacist.

Use in adults

Your doctor will supervise the treatment, as the dose and duration of therapy depend on your 25-hydroxycolecalciferol (25(OH)D) level in the blood, the severity of your disease, and your response to treatment.

Recommended dose: 1 orodispersible film of 25,000 IU per week for the first month. After the first month of treatment, your doctor may consider reducing the dose.

Alternatively, national dosage recommendations for the treatment of vitamin D deficiency can be followed.

Use in children and adolescents

Ditralia is not intended for use in children and adolescents under 18 years of age.

Instructions for use

The orodispersible film should be placed in the mouth, on the tongue, and allowed to dissolve before swallowing. It should be taken immediately after removal from the sachet. Ditralia can be taken with or without food.

Important: Do not handle the orodispersible film with wet hands.

  • Take the sachet, locate the arrow symbol on the top of the sachet, and hold it with this side facing up. The sachet is not sealed in this area.

Hand pressing the gray oval applicator with the thumb on a flat surface

  • Gently peel apart the two parts of the sachet.

To do this, hold each part with one hand, using your thumb and index finger.

Hand holding an auto-injector with the tip applied to the skin of the upper right abdomen

  • Carefully pull the two parts of the sachet in opposite directions until they separate.

You will see the orodispersible film placed in one of the separated parts of the sachet.

Hands holding a gray rectangular medical device with a central transparent window

  • Remove the orodispersible film from the sachet with dry fingers and place it in your mouth, directly on the tongue. It will dissolve quickly and can be swallowed easily.

Hand placing a sublingual tablet under the tongue with the mouth slightly open

If you take more Ditralia than you should

If you take an excessive dose of Ditralia, consult your doctor or pharmacist immediately. Excess vitamin D causes an alteration of the calcium cycle in the body. The following symptoms may be experienced: weakness, fatigue, headache, nausea, vomiting, diarrhea (and in later stages, constipation), excessive urine production, urinary calcium, dry mouth, nocturia, intense thirst, loss of appetite, muscle and joint pain, abdominal pain, and arrhythmia.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

Emergency treatment:

Calcitonin, corticosteroid therapy (which prevents intestinal absorption of calcium), abundant hydration, diuretics to increase calcium content in the urine (furosemide), a low-calcium diet. High levels of calcium in the blood require immediate hospitalization.

If you forget to take Ditralia

Do not take a double dose to make up for forgotten doses.

If you stop taking Ditralia

Do not stop treatment unless you experience side effects. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop treatment with Ditralia and consult your doctor immediately

  • If you experience any of the following symptoms, as they may be a sign of an allergic reaction (hypersensitivity):
    • swelling of the face, lips, tongue, or throat
    • difficulty swallowing
    • hives
    • difficulty breathing

Uncommon side effects (may affect up to 1 in 100 people):

  • excess calcium in the blood (hypercalcemia)
  • excess calcium in the urine (hypercalciuria)

Rare side effects (may affect up to 1 in 1,000 people):

  • pruritus, skin rash, and urticaria

Frequency not known (cannot be estimated from the available data):

  • constipation, flatulence, nausea, abdominal pain, diarrhea

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing Ditralia

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the carton after EXP.

Do not store above 30°C.

Store the product in its original packaging to protect it from light.

Medicines should not be disposed of via wastewater or household waste. Return the containers and any unused medicines to the SIGRE collection point at your pharmacy. If you have any further questions on how to dispose of the containers and any unused medicines, ask your pharmacist. This will help protect the environment.

6. Contents of the pack and other information

Composition of Ditralia

The active substance is colecalciferol. Each film contains 625 micrograms of colecalciferol (vitamin D3), equivalent to 25,000 IU.

The other ingredients (excipients) are refined olive oil, purified water, maltodextrin, hydroxypropylbetadex, copovidone, mannitol (E421), glycerol (E422), polysorbate 80 (E433), mono-linoleate glycerol, titanium dioxide (E171), sucralose (E955), orange flavor*, ascorbic acid (E300), all-rac-alpha-tocopherol (E307), orange yellow (E110).

*contains:

Flavor: orange essential oil, terpene-free orange oil, terpene-free lemon oil, terpene-free mandarin oil, ethyl hexanoate, ethyl 2-methylbutyrate, ethyl butyrate, acetaldehyde

Additives: butylhydroxyanisole (E320), citric acid (E330)

Fillers: maltodextrin, arabic gum (E414)

Appearance and packaging of the product

Ditralia 25,000 IU is a rectangular, flexible, light orange film (15 mm x 30 mm).

The orodispersible film is presented in a pack containing 2 or 4 films for each concentration. Each sachet contains one orodispersible film.

Marketing Authorization Holder:

IBSA Farmaceutici Italia S.r.l.

Via Martiri di Cefalonia 2

26900 Lodi, Italy

Manufacturer:

IBSA Farmaceutici Italia S.r.l

S.S. n. 11 Padana Superiore Km 160

20051 Cassina de’ Pecchi (Mi), Italy

or

Altergon Italia Srl

Zona Industriale

83040 Morra de Sanctis (AV), Italy

You can request more information about this medicine by contacting the local representative of the Marketing Authorization Holder:

Instituto Bioquimico Iberico IBSA S.L.

Avenida Diagonal 605,

Planta 8, Local 1,

08028 Barcelona (Spain)

Date of last revision of this leaflet:

August 2024

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es

Online doctors for DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS

Discuss questions about DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (86)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

5.0 (198)
Doctor

Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

5.0 (939)
Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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5.0 (2)
Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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€66
5.0 (5)
Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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€86

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Frequently Asked Questions

Is a prescription required for DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS?

DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS?

The active ingredient in DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS is colecalciferol. This information helps identify medicines with the same composition but different brand names.

Who manufactures DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS?

DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS is manufactured by Ibsa Farmaceutici Italia S.R.L.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to DITRALIA 25,000 IU ORALLY DISINTEGRATING TABLETS?

Other medicines with the same active substance (colecalciferol) include ALDEXINA 25,000 IU HARD CAPSULES, ALDEXINA 50,000 IU HARD CAPSULES, BENFEROL CHOQUE 50,000 IU SOFT GEL CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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