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CRESEMBA 40 mg HARD CAPSULES

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About the medicine

How to use CRESEMBA 40 mg HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Cresemba, Hard Capsules 40mg

Cresemba, Hard Capsules 100mg

isavuconazonium

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor, pharmacist, or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What is Cresemba and what is it used for
  2. What you need to know before you take Cresemba
  3. How to take Cresemba
  4. Possible side effects
  5. Storage of Cresemba
  6. Contents of the pack and other information

1. What is Cresemba and what is it used for

What is Cresemba

Cresemba is an antifungal medicine that contains the active substance isavuconazonium.

How Cresemba works

Isavuconazonium works by killing or stopping the growth of the fungus that causes the infection.

What Cresemba is used for

Cresemba is used in adults and pediatric patients from 6 years of age to treat the following fungal infections:

  • invasive aspergillosis, caused by a fungus of the 'Aspergillus' group,
  • mucormycosis, caused by a fungus belonging to the 'Mucorales' group, in patients for whom treatment with amphotericin B is not appropriate.
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2. What you need to know before you take Cresemba

Do not take Cresemba

  • if you are allergic to isavuconazonium or any of the other ingredients of this medicine (listed in section 6),
  • if you have a heart rhythm problem called 'short QT syndrome',
  • if you are taking any of the following medicines:
    • ketoconazole, used for fungal infections,
    • high doses of ritonavir (more than 200 mg every 12 hours), used for HIV,
    • rifampicin, rifabutin, used for tuberculosis,
    • carbamazepine, used for epilepsy,
    • barbiturates such as phenobarbital, used for epilepsy and sleep disorders,
    • phenytoin, used for epilepsy,
    • St. John's Wort, a herbal medicine used for depression,
    • efavirenz, etravirine, used for HIV,
    • nafcillin, used for bacterial infections.

Warnings and precautions

Talk to your doctor or pharmacist or nurse before you start taking Cresemba:

  • if you have had an allergic reaction to another antifungal treatment with 'azole', such as ketoconazole, fluconazole, itraconazole, voriconazole, or posaconazole in the past,
  • if you have severe liver disease. Your doctor should monitor you for possible side effects.

Monitoring of side effects

Stop taking Cresemba and call your doctor immediately if you notice any of the following side effects:

  • sudden wheezing, difficulty breathing, swelling of the face, lips, mouth, or tongue, intense itching, sweating, dizziness, or fainting, rapid heartbeat or palpitations in the chest: these may be signs of a severe allergic reaction (anaphylaxis).

Changes in liver function

Cresemba may sometimes affect liver function. Your doctor may perform blood tests while you are taking this medicine.

Skin problems

Call your doctor immediately if you experience severe skin peeling, mouth, eyes, or genital areas.

Children and adolescents

Do not give Cresemba capsules to children between 1 and less than 6 years of age, as this medicine has not been studied in this age group. For children from 6 years of age and adolescents with a body weight of at least 32 kg, your doctor may prescribe Cresemba 100 mg capsules. Other forms of the medicine are more suitable for children or adolescents who cannot swallow capsules; consult your doctor or pharmacist.

Other medicines and Cresemba

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines. Some medicines may change the way Cresemba works or Cresemba may change the way other medicines work if taken at the same time.

In particular, do not take this medicine and tell your doctor or pharmacist if you are taking any of the following medicines:

  • ketoconazole, used for fungal infections,
  • high doses of ritonavir (more than 200 mg every 12 hours), used for HIV,
  • rifampicin, rifabutin, used for tuberculosis,
  • carbamazepine, used for epilepsy,
  • barbiturates such as phenobarbital, used for epilepsy and sleep disorders,
  • phenytoin, used for epilepsy,
  • St. John's Wort, a herbal medicine used for depression,
  • efavirenz, etravirine, used for HIV,
  • nafcillin, used for bacterial infections.

Unless your doctor tells you otherwise, do not take this medicine and tell your doctor or pharmacist if you are taking any of the following medicines:

  • rufinamide or any other medicine that reduces the QT interval on the electrocardiogram (ECG),
  • aprepitant, used to prevent nausea and vomiting in cancer treatment,
  • prednisone, used for rheumatoid arthritis,
  • pioglitazone, used for diabetes.

Tell your doctor or pharmacist if you are taking any of the following medicines, as it may be necessary to adjust or monitor the dose to ensure that the medicines continue to have the desired effect:

  • cyclosporine, tacrolimus, and sirolimus, used to prevent transplant rejection,
  • cyclophosphamide, used for cancer,
  • digoxin, used to treat heart failure or irregular heartbeat,
  • colchicine, used to treat gout attacks,
  • dabigatran etexilate, used to prevent blood clots after hip or knee replacement surgery,
  • clarithromycin, used for bacterial infections,
  • saquinavir, fosamprenavir, indinavir, nevirapine, lopinavir/ritonavir combination, used for HIV,
  • alfentanil or fentanyl, used for severe pain,
  • vincristine, vinblastine, used for cancer,
  • mycophenolate mofetil (MMF), used in transplant patients,
  • midazolam, used for severe insomnia and stress,
  • bupropion, used for depression,
  • metformin, used for diabetes,
  • daunorubicin, doxorubicin, imatinib, irinotecan, lapatinib, mitoxantrone, topotecan, used for different types of cancer.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Do not take Cresemba if you are pregnant, unless your doctor tells you otherwise. As it is not known whether it can affect or harm the fetus.

Cresemba should not be used during breastfeeding.

Driving and using machines

Cresemba may make you feel confused, tired, or drowsy. It may also cause fainting. Therefore, be very careful when driving or operating machinery.

3. How to take Cresemba

Follow the instructions for administration of this medicine exactly as indicated by your doctor or pharmacist. If you are unsure, consult your doctor or pharmacist again.

The recommended dose is as follows:

Adult patients

Loading dose

(3 times a day)1

Maintenance dose

(1 time a day)2

Every 8hours during days1 and 2

Total daily dose during days1 and 2

2 capsules of 100 mg

6 capsules of 100 mg

2 capsules of 100 mg

1 Six administrations in total.

2 Starts between 12 and 24 hours after the last loading dose.

Pediatric patients from 6 to 18years of age

Body weight (kg)

Loading dose

(every 8hours during the first 48hours)1

Total daily dose during days1 and 2

Maintenance dose (once a day)2

From 16 kg to <18 kg

2 capsules of 40 mg

6 capsules of 40 mg

2 capsules of 40 mg

From 18 kg to <25 kg

3 capsules of 40 mg

9 capsules of 40 mg

3 capsules of 40 mg

From 25 kg to <32 kg

4 capsules of 40 mg

12 capsules of 40 mg

4 capsules of 40 mg

≥32 kg to < 37 kg

1 capsule of 100 mg and2 capsules of 40 mg

3 capsules of 100 mg and6 capsules of 40 mg

1 capsule of 100 mg and2 capsules of 40 mg

≥37 kg

5 capsules of 40 mg

or

2 capsules of 100 mg

15 capsules of 40 mg

or

6 capsules of 100 mg

5 capsules of 40 mg

or

2 capsules of 100 mg

1 Six administrations in total.

2 Starts between 12 and 24 hours after the last loading dose.

Use in children and adolescents

The use of Cresemba 100 mg capsules has not been studied in children and adolescents. Your doctor may prescribe Cresemba 100 mg capsules to children and adolescents with a body weight of at least 32 kg.

Other forms of the medicine are more suitable for children or adolescents who cannot swallow capsules; consult your doctor or pharmacist.

You should take this dose until your doctor tells you otherwise. The duration of treatment with Cresemba may be more than 6 months, if your doctor considers it necessary.

The capsules can be taken with or without food. Swallow the capsules whole. Do not chew, crush, dissolve, or open the capsules.

If you take more Cresemba than you should

If you take more Cresemba than you should, talk to a doctor or go to the hospital immediately. Take the medicine package with you to show the doctor what you have taken.

It may cause more side effects such as:

  • headache, feeling dizzy, agitation, or drowsiness,
  • tingling, decreased sensitivity, or tactile sensation,
  • problems perceiving things, hot flashes, anxiety, joint pain,
  • altered taste, dry mouth, diarrhea, vomiting,
  • palpitations, increased heart rate, increased sensitivity to light.

If you forget to take Cresemba

Take the capsule as soon as you remember. However, if it is almost time for the next dose, skip the missed dose.

Do not take a double dose to make up for the missed doses.

If you stop taking Cresemba

Do not stop taking Cresemba unless your doctor has told you to. It is important to continue treatment with this medicine until your doctor tells you to. This is to ensure that the fungal infection has disappeared.

If you have any other questions about the use of this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking Cresemba and call your doctor immediately if you notice any of the following side effects:

  • a severe allergic reaction (anaphylaxis) such as sudden wheezing, difficulty breathing, swelling of the face, lips, mouth, or tongue, intense itching, sweating, dizziness, or fainting, rapid heartbeat or palpitations in the chest.

Call your doctor immediately if you notice any of the following side effects:

  • severe skin peeling, mouth, eyes, or genital areas.

Other side effects

Tell your doctor, pharmacist, or nurse if you notice any of the following side effects:

Common:may affect up to 1 in 10 people

  • reduced potassium levels in the blood,
  • decreased appetite,
  • confusion (delirium),
  • headache,
  • drowsiness,
  • inflamed veins that can cause blood clots,
  • sudden shortness of breath or severe respiratory problems,
  • nausea, vomiting, diarrhea, and stomach pain,
  • changes in blood tests of liver function,
  • skin rash, itching,
  • kidney failure (symptoms may include swelling of the legs),
  • chest pain, feeling tired or drowsy.

Uncommon:may affect up to 1 in 100 people

  • reduced white blood cell count, may increase the risk of infection and fever,
  • reduced platelet count, may increase the risk of bleeding or bruising,
  • reduced red blood cell count, may make you feel weak or short of breath or pale,
  • severe reduction in the number of blood cells, may make you feel weak, cause bruising, or increase the likelihood of infections,
  • skin rash, swelling of the lips, mouth, tongue, or throat with difficulty breathing (hypersensitivity),
  • low blood sugar levels,
  • low magnesium levels in the blood,
  • low levels of a protein called 'albumin' in the blood,
  • malnutrition,
  • low sodium levels in the blood (hyponatremia),
  • depression, difficulty sleeping,
  • stroke, fainting, or feeling faint, dizziness,
  • tingling, numbness, or prickling sensation in the skin (paresthesia),
  • alterations in mental status (encephalopathy),
  • altered taste (dysgeusia),
  • 'spinning' sensation or dizziness (vertigo),
  • heart rhythm problems, may be too fast, or irregular, or extra heartbeat, this may appear on your electrocardiogram or ECG,
  • circulatory problems,
  • low blood pressure,
  • wheezing, rapid breathing, coughing up blood or bloody sputum, nosebleeds,
  • indigestion,
  • constipation,
  • abdominal distension (bloating),
  • enlarged liver,
  • liver inflammation,
  • skin problems, red or purple spots on the skin (petechiae), skin inflammation, hair loss,
  • back pain,
  • swelling of the limbs,
  • feeling weak, very tired, drowsy, feeling unwell (malaise).

Side effects with unknown frequency:

  • anaphylaxis (a severe allergic reaction).

Reporting of side effects

If you experience any side effects, talk to your doctor, pharmacist, or nurse, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system included in Appendix V. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Cresemba

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the label after EXP. The expiry date is the last day of the month indicated.

Do not store above 30°C.

Store in the original packaging to protect from moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Cresemba

  • The active substance is isavuconazole. Each capsule contains 74.5 mg of isavuconazonium sulfate, equivalent to 40 mg of isavuconazole (for Cresemba 40 mg hard capsules) or 186.3 mg of isavuconazonium sulfate, equivalent to 100 mg of isavuconazole (for Cresemba 100 mg hard capsules).
  • The other ingredients are:
  • Capsule content: magnesium citrate (anhydrous), microcrystalline cellulose (E460), talc (E553b), colloidal anhydrous silica, stearic acid.
  • Capsule shell for Cresemba 40 mg hard capsules: hypromellose, red iron oxide (E172), titanium dioxide (E171).
  • Capsule shell for Cresemba 100 mg hard capsules: hypromellose, red iron oxide (E172) (only in the capsule body), titanium dioxide (E171), gellan gum, potassium acetate, disodium edetate, sodium lauryl sulfate.
  • Printed ink: shellac (E904), propylene glycol (E1520), potassium hydroxide, black iron oxide (E172).

Appearance of Cresemba and Package Contents

Cresemba 40 mg hard capsules are brown-red capsules with the cap marked with “CR40” in black ink.

Cresemba 100 mg hard capsules are capsules with the brown-red body marked with “100” in black ink and a white cap marked with "C" in black ink.

Cresemba 40 mg hard capsules are available in boxes with 35 capsules. Each box contains 7 aluminum blisters with 5 capsules each.

Cresemba 100 mg hard capsules are available in boxes with 14 capsules. Each box contains 2 aluminum blisters with 7 capsules each.

Each capsule is connected to a bag with a ‘desiccant’ to protect the capsule from moisture.

Do not puncture the blister with the desiccant.

Do not ingest or use the desiccant.

Marketing Authorization Holder:

Basilea Pharmaceutica Deutschland GmbH

Marie-Curie-Strasse 8

79539 Lörrach

Germany

Manufacturer:

Almac Pharma Services (Ireland) Limited

Finnabair Industrial Estate

Dundalk

Co. Louth

A91 P9KD

Ireland

Almac Pharma Services Limited

Seagoe Industrial Estate

Craigavon, Co. Armagh

BT63 5UA

United Kingdom (Northern Ireland)

You can request more information about this medication by contacting the local representative of the marketing authorization holder:

België/Belgique/Belgien

Pfizer SA/NV

Tel/Tél: +32 (0)2 554 62 11

Lietuva

Pfizer Luxembourg SARL filialas Lietuvoje

Tel: +3705 2514000

Text in Bulgarian language with contact information of Pfizer Luxembourg SARL, Clon Bulgaria, and phone number

Luxembourg/Luxemburg

Pfizer SA/NV

Tél/Tel: +32 (0)2 554 62 11

Ceská republika

Pfizer s.r.o.

Tel: +420-283-004-111

Magyarország

Pfizer Kft.

Tel.: + 36 1 488 37 00

Danmark

Unimedic Pharma AB

Tlf.: +46 (0) 10-130 99 50

Malta

Vivian Corporation Ltd.

Tel: +35621 344610

Deutschland

PFIZER PHARMA GmbH

Tel: +49 (0)30 550055-51000

Nederland

Pfizer bv

Tel: +31 (0)800 63 34 636

Eesti

Pfizer Luxembourg SARL Eesti filiaal

Tel: +372 666 7500

Norge

Unimedic Pharma AB

Tlf: +46 (0) 10-130 99 50

Ελλ?δα

Pfizer ΕΛΛΑΣ A.E.

Τηλ: +30 210 67 85 800

Österreich

Pfizer Corporation Austria Ges.m.b.H.

Tel: +43 (0)1 521 15-0

España

Pfizer S.L.

Tel: +34 91 490 99 00

Polska

Pfizer Polska Sp. z o.o.

Tel.: +48 22 335 61 00

France

Pfizer

Tél: +33 (0)1 58 07 34 40

Portugal

Laboratórios Pfizer, Lda.

Tel: +351 21 423 5500

Hrvatska

Pfizer Croatia d.o.o.

Tel: +385 1 3908 777

România

Pfizer România S.R.L.

Tel: +40 (0) 21 20 728 00

Ireland

Pfizer Healthcare Ireland Unlimited Company

Tel: +1800 633 363 (toll free)

+44 (0)1304 616161

Slovenija

Pfizer Luxembourg SARL

Pfizer, podružnica za svetovanje s podrocja

farmacevtske dejavnosti, Ljubljana

Tel: + 386 (0) 1 52 11 400

Ísland

Unimedic Pharma AB

Sími: +46 (0) 10-130 99 50

Slovenská republika

Pfizer Luxembourg SARL, organizacná zložka

Tel: +421-2-3355 5500

Italia

Pfizer S.r.l.

Tel: +39 06 33 18 21

Suomi/Finland

Unimedic Pharma AB

Puh/Tel: +46 (0) 10-130 99 50

Κ?προς

Pfizer ΕΛΛΑΣ Α.Ε. (CYPRUS BRANCH)

Τηλ: +357 22 817690

Sverige

Unimedic Pharma AB

Tel: +46 (0) 10-130 99 50

Latvija

Pfizer Luxembourg SARL filiale Latvija

Tel: +371 670 35 775

Date of the Last Revision of this Prospectus:

Other Sources of Information

Detailed information about this medication is available on the European Medicines Agency website: https://www.ema.europa.eu. There are also links to other websites about rare diseases and orphan medicines.

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Discuss questions about CRESEMBA 40 mg HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

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  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
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Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

Patients commonly seek his care for:

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
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  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
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  • Second opinion on diagnoses and treatment plans.
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  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

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  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
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  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
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Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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€50

Frequently Asked Questions

Is a prescription required for CRESEMBA 40 mg HARD CAPSULES?
CRESEMBA 40 mg HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in CRESEMBA 40 mg HARD CAPSULES?
The active ingredient in CRESEMBA 40 mg HARD CAPSULES is isavuconazole. This information helps identify medicines with the same composition but different brand names.
Who manufactures CRESEMBA 40 mg HARD CAPSULES?
CRESEMBA 40 mg HARD CAPSULES is manufactured by Basilea Pharmaceutica Deutschland Gmbh. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of CRESEMBA 40 mg HARD CAPSULES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether CRESEMBA 40 mg HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to CRESEMBA 40 mg HARD CAPSULES?
Other medicines with the same active substance (isavuconazole) include CRESEMBA 100 mg HARD CAPSULES, CRESEMBA 200 mg POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION, CANADIOL 100 mg CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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