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COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Patient Information Leaflet

Colpermin 187 mg hard gastro-resistant capsules

Peppermint oil

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
  • You should consult a doctor if your symptoms worsen or do not improve after 2 weeks.

Contents of the pack

  1. What is Colpermin and what is it used for
  2. What you need to know before you take Colpermin
  3. How to take Colpermin
  4. Possible side effects
  5. Storing Colpermin
  6. Package contents and further information

1. What is Colpermin and what is it used for

Colpermin is a herbal medicine that contains peppermint oil.

Colpermin capsules are indicated for the symptomatic relief of mild gastrointestinal spasms, flatulence, and abdominal pain, particularly in patients with irritable bowel syndrome.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you take Colpermin

Do not take Colpermin

  • If you are allergic to peppermint oil, menthol, or any of the other ingredients of this medicine (listed in section 6).
  • If your doctor has told you that you have a liver disease.
  • If you have inflammation of the bile duct (cholangitis).
  • If you have a low production of stomach acid (a condition called achlorhydria).
  • If you have gallstones or any other biliary disorder.
  • In children under 8 years of age.

Colpermin contains peanut oil

Do not use this medicine if you are allergic to peanuts or soya.

Warnings and precautions

Consult your doctor or pharmacist before taking Colpermin.

Tell your doctor or pharmacist if you have heartburn or a hiatus hernia (a condition where part of the stomach protrudes into the chest cavity). In these cases, taking this medicine could worsen symptoms and treatment should be discontinued.

Colpermin capsules should be swallowed whole, without being broken or chewed, and should not be taken with food. This could cause the premature release of peppermint oil and irritation of the mouth and upper digestive tract (esophagus).

Children

The use of this medicine is recommended for children from 8 years of age and should not be used in children under this age (8 years).

Other medicines and Colpermin

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.

Taking other medicines that reduce stomach acid (such as H2 receptor antagonists and proton pump inhibitors) or antacids at the same time as this medicine could cause the premature release of peppermint oil. Therefore, they should be taken at least 2 hours before or after taking this medicine.

Using Colpermin with food and drinks

Eating food at the same time as taking this medicine could cause the premature release of peppermint oil. Therefore, this medicine should be taken at least 30 minutes before or after food.

Pregnancy and breastfeeding

Due to insufficient data, use during pregnancy and breastfeeding is not recommended, nor in women of childbearing age who are not using contraceptive methods.

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

This medicine has no or negligible influence on the ability to drive and use machines.

3. How to take Colpermin

Follow exactly the administration instructions of the medicine contained in this leaflet or as indicated by your doctor or pharmacist. If in doubt, consult your doctor or pharmacist again.

Use in adults and the elderly

The recommended dose is 1 capsule 3 times a day. The dose may be increased to a maximum of 2 capsules 3 times a day if necessary.

Use in adolescents from 12 to 17 years of age

The recommended dose is 1 capsule 3 times a day.

Use in children from 8 to 11 years of age

The recommended dose is 1 capsule 2 times a day.

Children under 8 years of age

This medicine should not be used in children under 8 years of age.

Special populations

No data are available on the dosage in case of renal insufficiency.

The route of administration is oral. Colpermin capsules should be swallowed whole with a sufficient amount of liquid to allow the capsule to pass comfortably. Do not chew, crush, or break the capsules.

Be careful when removing the capsules from the blister strip.

Colpermin should be taken at least 30 minutes before or after food.

The usual duration of treatment is 1 or 2 weeks. The maximum duration of treatment is 3 months per treatment course. If symptoms persist, inform your doctor or pharmacist.

If you take more Colpermin than you should

Symptoms of an overdose may be:

  • Severe gastrointestinal symptoms, such as diarrhea, rectal ulcers, or nausea.
  • Epileptic seizures, loss of consciousness, difficulty breathing.
  • Cardiac rhythm disturbances
  • Lack of coordination of muscle movements and other central nervous system problems.

In case of overdose, seek advice from your doctor or pharmacist.

If you forget to take Colpermin

If you miss a dose at the right time, simply take the next dose as usual. Do not take a double dose to make up for forgotten doses.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

If you stop taking Colpermin

No rebound effect is expected.

Take Colpermin for the time your doctor or pharmacist has indicated. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking this medicine and seek urgent medical attention

If you develop severe allergic reactions, including anaphylactic shock (a severe, sudden allergic reaction with signs such as low blood pressure and difficulty breathing), which requires immediate medical treatment, mild or severe tremors, movement disorders with balance problems, decreased heart rate, and red skin rash. The frequency of these reactions is unknown.

The following side effects have been reported with the approximate frequencies indicated:

Common:may affect up to 1 in 10 people

Headache, heartburn (acidity), anal discomfort, abnormal-smelling stools, dry mouth, feeling of unease, and stomach discomfort and nausea, and vomiting.

Uncommon:may affect up to 1 in 100 people

Hypersensitivity, skin itching, gastric bleeding, and blurred vision.

Frequency not known: cannot be estimated from the available data

Pain around the anus, diarrhea, difficulty and pain when urinating, inflammation of the head of the penis (glans), and abnormal-smelling urine.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storing Colpermin

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and blister strip after EXP. The expiry date is the last day of the month stated.

Do not store above 25°C. Store in the original package to protect from light and moisture.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Package contents and further information

Colpermin composition

  • The active substance is peppermint oil. Each hard gastro-resistant capsule contains 187 mg (0.2 ml) of Mentha x piperitaL., aetheroleum (peppermint oil).
  • The other ingredients are:

Contents of the capsule:

  • White beeswax
  • Peanut oil (refined Arachis hypogaeaL. oil)
  • Colloidal anhydrous silica

Capsule shell:

  • Gelatin
  • Indigotine (E132)
  • Titanium dioxide (E171)
  • Methacrylic acid-methyl methacrylate copolymer (1:2)
  • Methacrylic acid-ethyl acrylate copolymer (1:1) – 30% dispersion
  • Triethyl citrate
  • Glycerol monostearate 40-55
  • Macrogol 4000
  • Talc.

Appearance and package contents

The body of the Colpermin hard gastro-resistant capsule is opaque, light blue; the cap is opaque, blue, with a dark blue stripe between the body and the cap.

Colpermin capsules are packaged in blister strips of 10 capsules and each carton may contain 30 or 100 hard gastro-resistant capsules (3 or 10 blister strips). Not all pack sizes may be marketed.

Marketing authorisation holder

Tillotts Pharma GmbH

Warmbacher Strasse 80

79618 Rheinfelden, Germany

Manufacturer

Tillotts Pharma GmbH

Warmbacher Strasse 80

79618 Rheinfelden,

Germany

You can obtain further information on this medicine from the local representative of the marketing authorisation holder:

TILLOTTS PHARMA SPAIN, S.L.U.

Travessera de Gràcia 58, 5º 3ª

08006 Barcelona

Spain

This medicine is authorised in the Member States of the EEA under the following names:

Belgium, Denmark, Finland, France, Germany, Iceland, Luxembourg, Netherlands, Norway, Portugal, Spain, Sweden: Colpermin

Austria: Pfefferminzöl Tillotts 187 mg magensaftresistente Hartkapseln

Date of last revision of this leaflet:September 2022

Other sources of information

Detailed and up-to-date information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES

Discuss questions about COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

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When to consult Dr. Chekhun:

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Consultation format

Dr. Chekhun provides online consultations, where you can receive:

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Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

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If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Taisiia Proida

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Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

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Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Frequently Asked Questions

Is a prescription required for COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES?

COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES?

The active ingredient in COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES is menthae piperitae aetheroleum. This information helps identify medicines with the same composition but different brand names.

Who manufactures COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES?

COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES is manufactured by Tillotts Pharma Gmbh. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to COLPERMIN 187 mg GASTRO-RESISTANT HARD CAPSULES?

Other medicines with the same active substance (menthae piperitae aetheroleum) include AERO RED 40 mg CHEWABLE TABLETS, AERO-RED 120 mg CHEWABLE TABLETS, AERO-RED FORTE 240 mg SOFT CAPSULES. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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