Bg pattern

COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION

Prescription review online

Prescription review online

A doctor will review your case and decide whether a prescription is medically appropriate.

Talk to a doctor about this medicine

Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

Show original

Introduction

Package Leaflet: Information for the User

Colfinair 2 million UIpowder for solution for inhalation by nebulizer

colistimethate sodium

Read all of this leaflet carefully before you start using this medicine, because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the package leaflet:

  1. What is Colfinair and what is it used for
  2. What you need to know before you use Colfinair
  3. How to use Colfinair
  4. Possible side effects
  5. Storage of Colfinair
  6. Contents of the pack and further information

1. What is Colfinair and what is it used for

Antibiotics are used to treat bacterial infections and are not effective against viral infections.

It is essential that you follow the instructions regarding dosage, administration interval, and treatment duration as indicated by your doctor.

Do not store or reuse this medication. If you have any leftover antibiotic after completing treatment, return it to the pharmacy for proper disposal. Do not dispose of medications through the drain or in the trash.

Colfinair is administered by inhalation to treat chronic respiratory infections in patients with cystic fibrosis. Colfinair is used when these infections are caused by a specific bacterium called Pseudomonas aeruginosa.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Colfinair

Do not use Colfinair

  • If you are allergic (hypersensitive) to colistimethate sodium, colistin, or other polymyxins.

Warnings and precautions

Consult your doctor, pharmacist, or nurse before starting to use Colfinair:

  • If you have or have had kidney problems
  • If you have myasthenia gravis
  • If you have porphyria
  • If you have asthma.

In premature infants and newborns, caution should be exercised when using Colfinair because the kidneys are not yet fully developed.

Coughing and chest tightness may lead to interruption. This can be alleviated with the use of an inhaled bronchodilator (e.g., salbutamol) before using Colfinair. Your doctor will supervise your first dose of Colfinair and check your lung function before and after administration.

If, despite using a bronchodilator, you experience chest tightness, inform your doctor because this may indicate an allergic reaction and treatment should be discontinued.

During treatment with Colfinair, neurotoxicity may occur with possible dizziness, confusion, or visual disturbances. If you experience side effects such as dizziness, confusion, or visual disturbances, or any not mentioned in this leaflet, inform your doctor.

Taking Colfinair with other medicines

  • medicines that may affect how your kidneys work. Taking these medicines at the same time as Colfinair may increase the risk of kidney damage
  • medicines that may affect the nervous system. Taking these medicines at the same time as Colfinair may increase the risk of side effects on your nervous system
  • medicines called muscle relaxants, often used during general anesthesia. Colfinair may increase the effects of these medicines. If you are going to be given a general anesthetic, inform your anesthesiologist that you are using Colfinair.

If you have myasthenia gravis and are also taking other antibiotics called macrolides (such as azithromycin, clarithromycin, or erythromycin), or antibiotics called fluoroquinolones (such as ofloxacin, norfloxacin, and ciprofloxacin), taking Colfinair increases the risk of muscle weakness and respiratory difficulties even more.

Receiving colistimethate sodium by infusion at the same time as receiving Colfinair by inhalation may increase your risk of experiencing side effects.

Colfinair must not be mixed with any other medicine in the nebulizer!

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

Colfinair has a moderate influence on the ability to drive and use machines. During treatment with Colfinair, neurotoxicity may occur with possible dizziness, confusion, or visual disturbances. If you experience any side effects such as dizziness, confusion, or visual disturbances, do not drive or use machines and consult your doctor or pharmacist.

3. How to use Colfinair

Colfinair is for inhalation use only.

Follow the instructions for administration of this medicine exactly as indicated by your doctor. If in doubt, consult your doctor or pharmacist again.

The recommended dose is:

Proposed dose

Maximum daily dose

Adults, Adolescents (12 to 17 years), Children (2 to 11 years)

1-2 million units two or three times a day

6 million units

Children under 2 years

0.5-1 million units, twice a day

2 million units

Your doctor may decide to adjust the dose depending on your circumstances. If you are also taking other inhaled medicines, your doctor will tell you in what order to take them.

Note that Colfinair is also available in a vial of 1 million UI, which may be a more suitable dose depending on the dosage prescribed by your doctor.

For use in children under 2 years of age, PARI LC SPRINT Baby (red nozzle adapter) with a mask is recommended.

Your doctor will tell you how long your treatment with Colfinair will last. Do not stop treatment early because when treating bacterial infections, it is essential to complete the full course of treatment to reduce the risk of developing resistance to the infectious bacteria.

Preparation for inhalation treatment

If you are being treated at home, your doctor or nurse will show you how to use Colfinair in your nebulizer when you start this treatment.

To start your treatment, you will need the following:

  • A 10 ml vial of Colfinair 2 million UI
  • 4 ml of sterile NaCl 0.9% solution for inhalation to dissolve the powder
  • A suitable nebulizer for inhalation use of Colfinair (e.g., eFlowrapidor PARI LC SPRINT)

How to prepare Colfinair for inhalation

Before you can introduce Colfinair into the nebulizer and inhale it, it must be dissolved with 3 ml of sterile NaCl 0.9% solution for inhalation. An ampoule contains the correct volume to dissolve Colfinair.

Colfinair must be used immediately after dissolution. Do not dissolve Colfinair until you are ready to administer a dose (see also section 5).

Hands holding a medicine vial and preparing to remove the upper protective cap

Step 1

Take a Colfinair vial and gently tap the glass vial so that the powder settles at the bottom. This ensures that you receive the correct dose of the medication. Open the vial by lifting the upper plastic cap of lavender color.

Medicine bottle with gray cap and hands holding tweezers extracting something from the inside

Step 2

Remove the lavender-colored plastic cap along with the metal ring from the vial.

Glass bottle with cap and a hand holding it while removing the upper protector with an arrow indicating the direction

Step 3

Twist off the lavender-colored cap in the direction of the arrow. Proper completion will allow you to twist off the metal ring. Twist off the metal ring from the side so that the break point on the opposite side bends. Remove the metal ring from the vial. Carefully discard the ring and cap.

Hands holding a vial and a rubber stopper preparing to seal the transparent vial

Step 4

Carefully remove the rubber stopper.

Step 5

  • Add 4 ml of sterile NaCl 0.9% solution for inhalation to Colfinair 2 million UI (lavender cap)
  • Replace the rubber stopper and gently turn the vial twice.
  • Roll the vial gently between your hands to dissolve all visible Colfinair powder at the bottom and side of the vial. Do not shake the vial too hard, as this can cause the solution to foam.
  • Once most of the powder has dissolved, let the vial sit for a few minutes to allow the foam to disappear and the remaining powder to dissolve.

Use Colfinair only when all the powder has dissolved and there are no visible particles in the solution

How to use Colfinair

Colfinair is for inhalation use only with a suitable nebulizer (e.g., eFlowrapidor PARI LC SPRINT).

Read the nebulizer's instructions for use carefully to obtain more information about handling the nebulization system.

It is essential that your nebulization system functions correctly before starting treatment with Colfinair.

Place the components of your nebulizer on a flat, clean surface and follow the manufacturer's instructions for use.

Inhalation should be done in a well-ventilated room.

After inhaling Colfinair

Consult the manufacturer's instructions for use of the nebulizer for cleaning and disinfecting it.

If you use more Colfinair than you should

If you have used more Colfinair than you should, consult your doctor or pharmacist immediately. If too much Colfinair is administered accidentally, the effects can be severe and may include kidney problems, muscle weakness, and respiratory difficulty (even arrest).

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 915 620 420 (indicating the medication and the amount ingested), or go to the nearest hospital.

If you forget to use Colfinair

If you are treating yourself and have forgotten a dose, you should take the forgotten dose as soon as you remember and then the next dose 8 or 12 hours later, and continue from then on as instructed.

Do not take a double dose to make up for forgotten doses.

If you stop using Colfinair

You must not stop using Colfinair as prescribed without consulting your doctor first.

If you have any other questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

An allergic reaction may occur. Severe allergic reactions can occur even with the first dose and may include rapid onset of rash, swelling of the face, tongue, and throat, inability to breathe due to narrowing of the airways, and loss of consciousness. Urgent medical attention will be needed.

If you think you have an allergic reaction to Colfinair, inform your doctor immediately.

Some side effects can be serious

Very common: may affect more than 1 in 10 people.

  • Feeling of chest tightness due to narrowing of the airways (may not always be a true allergic reaction)

Frequency not known: cannot be estimated from the available data.

  • Patients with severe kidney impairment and at higher doses may experience side effects known for intravenous administration
  • Confusion
  • Psychotic disorder
  • Visual disturbance
  • Dizziness

If you experience any of these effects, inform your doctor immediately.

Other possible side effects

Very common: may affect more than 1 in 10 people.

  • Sores in the mouth or throat
  • Cough
  • Breathing difficulties
  • Wheezing
  • Worsening of lung function test results
  • Transient absence of spontaneous breathing

If any of these problems affect you severely, inform your doctor.

Frequency not known: cannot be estimated from the available data.

  • Subjective skin sensations
  • Speech disorder
  • Dizziness
  • Kidney failure

Other possible side effects include thrush in the mouth or throat.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Medicines and Healthcare Products Agency (AEMPS) https://www.notificaram.es

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Colfinair

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton or vial label after EXP. The expiry date is the last day of the month indicated.

Do not store above 25°C.

Keep the vial in the outer carton to protect it from light.

Colfinair solution for inhalation by nebulizer should be used immediately after preparation. If this is not possible, a Colfinair solution should be stored in the refrigerator (2°C - 8°C) and not more than 24 hours.

If not used immediately, storage conditions and times are the responsibility of the user.

Any leftover solution should be discarded.

For single use only.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Colfinair

  • The active substance is colistimethate sodium.
  • Each 10 ml vial contains 2 million UI, which is equivalent to approximately 160 mg of colistimethate sodium.

Appearance and packaging of the product

Colfinair is a powder for solution for inhalation by nebulizer.

2 million UI/vial:

White powder in a 10 ml colorless glass vial with a lavender cap.

Also available:

1 million UI/vial:

White powder in a 10 ml colorless glass vial with a red cap.

The product is available in the following pack sizes:

Carton box containing:

  • 8 carton boxes of 7 vials each (56 vials),
  • 2 solution packs for inhalation of NaCl 0.9% with 30 ampoules of 4 ml each (60 ampoules), and a handheld nebulizer eFlowrapid.

Marketing authorization holder and manufacturer

PARI Pharma GmbH

Moosstrasse 3

82319 Starnberg

Germany

Tel.: +49 (0) 89/74 28 46 – 10

You can request more information about this medicine by contacting the local representative of the marketing authorization holder:

PARI Pharma Iberia S.L.

Miguel Yuste 17, 4th floor C.

28037 Madrid

This medicine is authorized in the Member States of the European Economic Area under the following names:

GermanyColiFin 2 Millionen. I.E. Pulver zur Herstellung einer Lösung für einen Vernebler

NetherlandsColiFin PARI 2.000.000 IE Poeder voor verneveloplossing

AustriaColiFin 2 Mio. I. E. Pulver zur Herstellung einer Lösung für einen Vernebler

SpainColfinair 2 million UI powder for solution for inhalation by nebulizer

ItalyColfinair 2.000.000 U Polvere per soluzione per nebulizzatore

Date of last revision of this leaflet: 05/2022

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION

Discuss questions about COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

0.0 (0)
Doctor

Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
  • chest discomfort, palpitations, dizziness, fatigue, and blood pressure concerns;
  • digestive problems: abdominal pain, nausea, diarrhoea, constipation, reflux;
  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders;
  • review and interpretation of lab tests, imaging reports, and medical documents;
  • medication review and treatment adjustment;
  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.
Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
Camera Book a video appointment
€55
0.0 (0)
Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Camera Book a video appointment
€58
5.0 (25)
Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Camera Book a video appointment
€70
5.0 (760)
Doctor

Alina Tsurkan

Family medicine 13 years exp.

Dr. Alina Tsurkan is a licensed family medicine physician based in Portugal, offering online consultations for adults and children. She provides professional primary care, with a focus on prevention, accurate diagnosis, and long-term management of acute and chronic conditions.

Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

Camera Book a video appointment
€55

Frequently Asked Questions

Is a prescription required for COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION?
COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION?
The active ingredient in COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION is colistin. This information helps identify medicines with the same composition but different brand names.
Who manufactures COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION?
COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION is manufactured by Pari Pharma Gmbh. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to COLFINAIR 2 MILLION IU POWDER FOR SOLUTION FOR NEBULIZER INHALATION?
Other medicines with the same active substance (colistin) include COLFINAIR 1 Million IU Powder for Solution for Nebulizer Inhalation, SODIUM COLISTIMETHATE ACCORD 1 Million IU POWDER FOR INJECTABLE SOLUTION AND FOR INFUSION, SODIUM COLISTIMETHATE ACCORD 2 Million IU POWDER FOR INJECTABLE SOLUTION AND FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
bg-pattern-dark

Stay informed about Oladoctor

News about new services, product updates and useful information for patients.

Follow us on social media