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CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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About the medicine

How to use CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Cisatracurium Hikma 2 mg/ml Solution for Injection and Infusion EFG

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Cisatracurium Hikma and what is it used for
  2. What you need to know before you use Cisatracurium Hikma
  3. How to use Cisatracurium Hikma
  4. Possible side effects
  5. Storage of Cisatracurium Hikma
  6. Contents of the pack and further information

1. What is Cisatracurium Hikma and what is it used for

Cisatracurium Hikma contains a medicine called cisatracurium. This belongs to a group of medicines called muscle relaxants.

Cisatracurium is used to:

  • relax muscles during surgical operations, including heart surgery, in adults and children over 1 month old;
  • help insert a tube into the windpipe (tracheal intubation), if a person needs help with breathing;
  • relax muscles in adults in intensive care.

Ask your doctor if you need more information about this medicine.

Doctor consultation

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2. What you need to know before you use Cisatracurium Hikma

Do not use Cisatracurium Hikma

  • if you are allergic to cisatracurium or other muscle relaxants or any of the other ingredients of this medicine (listed in section 6).
  • if you have had a bad reaction to an anaesthetic in the past.

Cisatracurium should not be given to you if you have any of the above conditions. If you are not sure, talk to your doctor, nurse or pharmacist before you are given this medicine.

Warnings and precautions

Tell your doctor, pharmacist or nurse before you start using this medicine if:

  • you have muscle weakness, tiredness or difficulty coordinating your movements (myasthenia gravis);
  • you have a nerve disease that causes muscle wasting, paralysis, motor neurone disease or cerebral palsy;
  • you have burns that need medical treatment;
  • you have ever had an allergic reaction to any muscle relaxant that you have been given during an operation.

If you are not sure if any of the above applies to you, talk to your doctor, nurse or pharmacist before you are given this medicine.

Other medicines and Cisatracurium Hikma

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. In particular, tell your doctor if you are taking any of the following medicines:

  • anaesthetics (used to reduce feeling and pain during surgery);
  • antibiotics (used to treat infections);
  • medicines used to treat irregular heartbeats (anti-arrhythmics);
  • medicines used to treat high blood pressure;
  • medicines that help get rid of fluids (diuretics), such as furosemide;
  • medicines for joint inflammation, such as chloroquine or D-penicillamine;
  • corticosteroids;
  • medicines for epilepsy (seizures), such as phenytoin or carbamazepine;
  • medicines for mental illness, such as lithium, monoamine oxidase inhibitors (MAOIs) or chlorpromazine (which can also be used for nausea);
  • medicines that contain magnesium;
  • medicines for Alzheimer's disease (anticholinesterases, such as donepezil).

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before you are given this medicine.

A harmful effect of cisatracurium on the baby cannot be excluded; however, it is unlikely to occur if breast-feeding is restarted after the effects of the substance have disappeared. Cisatracurium is rapidly eliminated from the body. Women should not breast-feed for 3 hours after the end of treatment.

Driving and using machines

If you are going to be in hospital for just one day, your doctor will tell you how long to wait before you can leave hospital or drive. It may be dangerous to drive soon after you have had an operation.

3. How to use Cisatracurium Hikma

Never try to give yourself this medicine. It should always be given by a person who is qualified to do so. Cisatracurium can be given:

  • as a single injection into a vein (intravenous bolus injection);
  • as a continuous infusion into a vein. This is when the medicine is given slowly over a long period of time.

Your doctor will decide how and how much of the medicine you will be given. This will depend on:

  • your body weight;
  • how much and how long you need muscle relaxation;
  • how you are expected to respond to the medicine.

This medicine should not be given to children under 1 month old.

If you have been given too much Cisatracurium Hikma

This medicine will always be given in carefully controlled conditions. However, if you think you have been given too much, tell your doctor or nurse immediately.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Allergic reactions (may affect up to 1 in 10,000 people)

If you get an allergic reaction, tell your doctor or nurse immediately. The signs may include:

  • sudden wheezing, chest pain or tightness;
  • swelling of the eyelids, face, lips, mouth or tongue;
  • skin rash or hives anywhere on the body;
  • collapse and anaphylactic shock.

Tell your doctor, nurse or pharmacist if you notice any of the following:

Common (may affect up to 1 in 10 people)

  • decrease in heart rate;
  • decrease in blood pressure.

Uncommon (may affect up to 1 in 100 people)

  • skin rash or redness;
  • wheezing or coughing.

Rare (may affect up to 1 in 10,000 people)

  • muscle weakness or pain.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Spanish Medicines and Healthcare Products Agency (AEMPS) website (http://www.aemps.gob.es/). By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Cisatracurium Hikma

  • Keep this medicine out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the carton after “EXP”. The expiry date refers to the last day of that month.
  • Store in a refrigerator (2°C - 8°C). Do not freeze.
  • Store in the original package to protect from light.
  • If diluted, store the infusion solution at 25°C or 2-8°C and use within 24 hours. Any unused infusion solution should be discarded 24 hours after preparation.
  • Medicines should not be disposed of via wastewater or household waste. Your doctor or nurse will dispose of any unused medicine. This will help protect the environment.

6. Contents of the pack and further information

What Cisatracurium Hikma contains

  • The active substance is 2 mg/ml cisatracurium (as besilate).
  • The other ingredients are benzenesulfonic acid (for pH adjustment) and water for injections.

Appearance and packaging

Cisatracurium Hikma 2 mg/ml Solution for Injection and Infusion is a colourless to pale yellow or yellowish-green solution, practically free from visible particles, and is available in:

  • Boxes of 5 and 10 glass ampoules of 2.5 ml (each 2.5 ml ampoule contains 5 mg of cisatracurium).
  • Boxes of 5 and 10 glass ampoules of 5 ml (each 5 ml ampoule contains 10 mg of cisatracurium).
  • Boxes of 5 and 10 glass ampoules of 10 ml (each 10 ml ampoule contains 20 mg of cisatracurium).

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Marketing authorisation holder

Hikma Farmacêutica (Portugal), S.A.

Estrada do Rio da Mó, 8, 8A e 8B - Fervença

2705-906 Terrugem SNT

Portugal

Manufacturer

Hikma Italia S.P.A.

Viale Certosa 10

27100 Pavia

Italy

You can obtain further information on this medicine from the representative of the marketing authorisation holder:

Hikma España, S.L.U.

Calle Anabel Segura nº11, Edificio A, planta 1ª, oficina 2

28108 - Alcobendas, Madrid

Spain

This medicine is authorised in the Member States of the European Economic Area under the following names:

Austria: Cisatracurium Hikma 2 mg/ml Injektionslösung oder Infusionslösung

Germany: Cisatracurium Hikma 2 mg/ml Injektionslösung /Infusionslösung

Belgium: Cisatracurium Hikma 2 mg/ml Injektions/Infusionslösung/Solution injectable/pour perfusion/ Oplossing voor injectie / infusie

Spain: Cisatracurio Hikma 2 mg/ml solución inyectable y para perfusión EFG

France: Cisatracurium Hikma 2 mg/ml Solution injectable/pour perfusion

Italy: Cisatracurio Hikma 2 mg/ml Soluzione iniettabile infusione

Netherlands: Cisatracurium Hikma 2 mg/ml Oplossing voor injectie/ infusie

Portugal: Cisatracúrio Hikma

United Kingdom: Cisatracurium 2 mg/ml Solution for injection/infusion

Date of last revision of this leaflet: July 2024

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) (http://www.aemps.gob.es/).

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This information is intended only for healthcare professionals:

This product is for single use only. Use only clear and almost colourless or slightly yellowish/greenish solutions. The product should be inspected visually before use, and if the appearance has changed or the container is damaged, the product should be discarded.

Diluted Cisatracurium Hikma remains physically and chemically stable for at least 24 hours at 2-8°C and 25°C at concentrations between 0.1 and 2 mg/ml in the following infusion fluids, either in polyvinyl chloride or polypropylene containers.

Intravenous infusion of sodium chloride (0.9% w/v).

Intravenous infusion of glucose (5% w/v).

Intravenous infusion of sodium chloride (0.18% w/v) and glucose (4.5% w/v) (one-fifth of the usual concentration of glucose).

Intravenous infusion of sodium chloride (0.45% w/v) and glucose (5% w/v).

In any case, since the product does not contain antimicrobial preservatives, dilution should be made immediately before use or, if this is not possible, it can be stored according to section 5 of the leaflet.

Cisatracurium Hikma has been shown to be compatible with the following drugs commonly used in surgical procedures, when mixed under conditions simulating intravenous infusion through a "Y" device: alfentanil hydrochloride, droperidol, fentanyl citrate, midazolam hydrochloride and sufentanil citrate. When other drugs are administered through the same needle or cannula as cisatracurium, it is recommended that each drug be flushed through with a suitable volume of an intravenous fluid, such as sodium chloride 0.9% w/v infusion.

As with other drugs administered intravenously, when a small vein is selected as the injection site, this medicine should be flushed through the vein with a suitable intravenous fluid, for example, sodium chloride 0.9% w/v infusion.

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Sergey Ilyasov

Psychiatry 7 years exp.

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

Camera Book a video appointment
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Frequently Asked Questions

Is a prescription required for CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?

CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?

The active ingredient in CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is cisatracurium. This information helps identify medicines with the same composition but different brand names.

Who manufactures CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?

CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is manufactured by Hikma Farmaceutica (Portugal) S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to CISATRACURIO HIKMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION?

Other medicines with the same active substance (cisatracurium) include CISATRACURIO ACCORDPHARMA 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, CISATRACURIO ACCORDPHARMA 5 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION, CISATRACURIO KALCEKS 2 mg/ml INJECTABLE SOLUTION AND PERFUSION SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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