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CEFIXIME CODAL 400 mg FILM-COATED TABLETS

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About the medicine

How to use CEFIXIME CODAL 400 mg FILM-COATED TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Cefixima Codal400 mg film-coated tablets EFG

cefixima

Read the entire package leaflet carefully before starting to take this medication, as it contains important information for you.

  • Keep this package leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor, pharmacist, or nurse.
  • This medication has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor, pharmacist, or nurse, even if they are side effects not listed in this package leaflet. See section 4.

Contents of the Package Leaflet

  1. What is Cefixima Codal and what is it used for
  2. What you need to know before taking Cefixima Codal
  3. How to take Cefixima Codal
  4. Possible side effects
  5. Storage of Cefixima Codal
  6. Package contents and additional information

1. What is Cefixima Codal and what is it used for

The active ingredient of Cefixima Codal is cefixime, a third-generation cephalosporin antibiotic. Cefixime works by eliminating the bacteria that cause the infection.

Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or common cold.

It is essential to follow the instructions regarding dosage, administration interval, and treatment duration as indicated by your doctor.

Do not store or reuse this medication. If you have any leftover antibiotic after completing the treatment, return it to the pharmacy for proper disposal. Do not throw medicines down the drain or in the trash.

It is indicated in the following infections, when it is believed that the causative bacteria are sensitive:

  • Acute otitis media (severe middle ear infection).
  • Upper respiratory tract infections (pharyngitis, tonsillitis, acute sinusitis).
  • Lower respiratory tract infections (acute exacerbations of chronic bronchitis, community-acquired pneumonia).
  • Urinary tract infections (acute cystitis, uncomplicated acute pyelonephritis).
  • Urethritis and cervicitis (inflammation of the urethra and cervix) due to gonorrhea, uncomplicated.
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2. What you need to know before taking Cefixima Codal

Do not take Cefixima Codal

  • If you are allergic to cefixime or to antibiotics of the penicillin class (beta-lactams). There is a rare possibility of a sudden and severe allergic reaction (anaphylactic reaction/anaphylactic shock) even with the first dose of antibiotics. Symptoms can include chest tightness, dizziness, discomfort (general feeling of discomfort, illness), fainting, or difficulty breathing, erythema (rash). If you experience any of these symptoms, seek medical help immediately and stop taking Cefixima Codal.
  • If you are allergic to any of the other components of this medication (listed in section 6).

Warnings and precautions

Consult your doctor, pharmacist, or nurse before starting to take Cefixima Codal.

Be particularly careful:

  • If you have renal insufficiency (it may be necessary to reduce the dose of Cefixima Codal).
  • If you are pregnant or breastfeeding.

Children

This medication is intended for children over 12 years old (or over 30 kg in weight).

Other medications and Cefixima Codal

Inform your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.

If you are taking anticoagulants (medicines that prevent blood clotting) in tablet form, your doctor may consider it necessary to perform more frequent checks.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

Driving and using machines

No cases of interference with cefixime and the ability to drive vehicles or use machines have been reported.

3. How to take Cefixima Codal

Follow the administration instructions for this medication exactly as indicated by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist again.

Cefixima Codal is for oral use.

The tablets should be swallowed with a glass of water. It is recommended to take Cefixima Codal at approximately the same time each day.

This medication can be taken with or without food.

The tablet can be divided into equal doses.

The recommended dose is:

Adults or children over 12 years old (or over 30 kg in weight): 400 mg per day (1 tablet), taken once a day.

In elderly patients, the same dose as in adults can be used, unless there is severe renal insufficiency (in which case the doctor should be consulted).

The duration of treatment varies depending on the type of infection being treated, generally ranging from 3 to 7 days, and should be completed in its entirety.

If you take more Cefixima Codal than you should

If you have taken more Cefixima Codal than you should, consult your doctor as soon as possible. Bring the package and this package leaflet with you to show your doctor.

If you forget to take Cefixima Codal

If you forget to take a dose, take it as soon as you remember on the same day. If you forget to take it one day, take the normal dose the next day. Do not take a double dose to make up for the missed dose.

If you interrupt treatment with Cefixima Codal

Continue taking Cefixima Codal until the end of the treatment, even if you feel better. All prescribed doses are required to combat the infection. If some bacteria survive, the infection may return or worsen again.

If you have any further questions about the use of this medication, ask your doctor, pharmacist, or nurse.

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4. Possible side effects

Like all medications, this medication can cause side effects, although not everyone will experience them.

The most common side effect of cefixime is diarrhea. You should stop taking Cefixima Codal and consult your doctor if the diarrhea is too frequent, persists, or worsens, or if the stools contain blood or mucus.

Common(may affect up to 1 in 10 people)

  • Diarrhea

Uncommon(may affect up to 1 in 100 people)

  • Headache
  • Abdominal pain, nausea (feeling of discomfort), and vomiting (being sick)
  • Red spots on the skin (rash)
  • Abnormal liver tests (increased transaminases and alkaline phosphatase)

Rare(may affect up to 1 in 1,000 people)

  • Eosinophilia (increased number of a type of blood cell, eosinophils)
  • Decreased platelet count or other blood cells
  • Increased bilirubin in the blood
  • Increased urea in the blood
  • Dizziness
  • Anorexia (potentially life-threatening eating disorder)
  • Heartburn
  • Jaundice (yellowing of the skin and sclera)
  • Itching of the skin
  • Rash (red spots on the skin) with eosinophilia and general symptoms (fever and swollen lymph nodes)
  • Erythema multiforme (red spots on the skin and mucous membranes with fever, discomfort, muscle pain, and weakness, and possibly vomiting)
  • Facial edema
  • Breathing difficulties

Very rare(may affect up to 1 in 10,000 people)

  • Antibiotic-associated colitis (swelling of the large intestine)
  • Severe allergic reaction
  • Urticaria
  • Stevens-Johnson syndrome (severe form of erythema multiforme)
  • Toxic epidermal necrolysis (most severe form of Stevens-Johnson syndrome, in which the top layer of the skin may peel off)
  • Renal failure
  • Increased serum creatinine

Reporting of side effects

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are possible side effects not listed in this package leaflet. You can also report them directly through the Spanish Medicines Monitoring System for Human Use: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medication.

5. Storage of Cefixima Codal

Keep this medication out of the sight and reach of children.

Do not use this medication after the expiration date stated on the carton, after "EXP". The expiration date is the last day of the month indicated.

Store below 25°C.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medication in the SIGRE collection point at the pharmacy. If you have any doubts, ask your pharmacist how to dispose of the packaging and any unused medication. This will help protect the environment.

6. Package contents and additional information

Composition of Cefixima Codal

  • The active ingredient is cefixime. Each film-coated tablet contains 447.68 mg of cefixime as trihydrate, equivalent to 400 mg of cefixime.
  • The other ingredients are

Core: microcrystalline cellulose (E460), calcium hydrogen phosphate dihydrate (E341), pregelatinized starch, magnesium stearate (E470b);

Coating: polyvinyl alcohol (E1203), titanium dioxide (E171), macrogol 3350 (E1521), macrogol 4000 (E1521), talc (E553b), red iron oxide (E172), yellow iron oxide (E172).

Appearance of the product and package contents

Cefixima Codal 400 mg are film-coated tablets of light brown color, oval, biconvex, scored on both sides, and measuring 18.2 ± 0.3 mm x 9.2 ± 0.3 mm.

The tablets are supplied in PVC-aluminum blisters.

Packaging sizes: 5, 6, 7, 8, 10, 12, and 100 film-coated tablets.

Not all packaging sizes may be marketed.

Marketing authorization holder

Codal-Synto Limited

Konstantinoupoleos 21

Limassol

3011

Cyprus

Manufacturer

Medochemie Ltd

1-10 Constantinoupoleos Street

Limassol

3011

Cyprus

Date of the last revision of this package leaflet:

July 2025

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Discuss questions about CEFIXIME CODAL 400 mg FILM-COATED TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

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When to consult Dr. Chekhun:

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Consultation format

Dr. Chekhun provides online consultations, where you can receive:

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Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

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Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Taisiia Proida

Family medicine 7 years exp.

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
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During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Frequently Asked Questions

Is a prescription required for CEFIXIME CODAL 400 mg FILM-COATED TABLETS?

CEFIXIME CODAL 400 mg FILM-COATED TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in CEFIXIME CODAL 400 mg FILM-COATED TABLETS?

The active ingredient in CEFIXIME CODAL 400 mg FILM-COATED TABLETS is cefixime. This information helps identify medicines with the same composition but different brand names.

Who manufactures CEFIXIME CODAL 400 mg FILM-COATED TABLETS?

CEFIXIME CODAL 400 mg FILM-COATED TABLETS is manufactured by Codal-Synto Limited. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of CEFIXIME CODAL 400 mg FILM-COATED TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether CEFIXIME CODAL 400 mg FILM-COATED TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy CEFIXIME CODAL 400 mg FILM-COATED TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy CEFIXIME CODAL 400 mg FILM-COATED TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to CEFIXIME CODAL 400 mg FILM-COATED TABLETS?

Other medicines with the same active substance (cefixime) include CEFIXIME MABO 200 mg FILM-COATED TABLETS, CEFIXIME MABO 400 mg FILM-COATED TABLETS, CEFIXIME NECLIFE 100 mg/5 ml ORAL SUSPENSION POWDER. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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