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ASACOL 1 G SUPPOSITORIES

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About the medicine

How to use ASACOL 1 G SUPPOSITORIES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the Patient

Asacol 1g Suppositories

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
    • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the Package Leaflet

  1. What Asacol 1 g Suppositories are and what they are used for
  2. What you need to know before you use Asacol 1 g Suppositories
  3. How to use Asacol 1 g Suppositories
  4. Possible side effects
    1. Storage of Asacol 1 g Suppositories
    2. Contents of the pack and further information

1. What Asacol 1 g Suppositories are and what they are used for

This medicine contains the active substance mesalazine, an anti-inflammatory drug used to treat inflammatory bowel disease.

This medicine is used to treat acute mild to moderate ulcerative proctitis (inflammation of the rectum).

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you use Asacol 1 g Suppositories

Do not use Asacol 1g Suppositories

  • if you are allergic to salicylic acid, salicylates such as acetylsalicylic acid (aspirin) or any of the other components of this medicine (listed in section 6),
  • if you have severe liver or kidney disease.

Warnings and Precautions

Consult your doctor before starting to use Asacol 1g Suppositories

  • If you have a history of or suffer from lung problems, particularly if you suffer from bronchial asthma.
  • If you have a history of allergy to sulfasalazine, a substance related to mesalazine.
  • If you have liver problems.
  • If you have kidney problems.
  • If you have ever suffered from a severe skin rash, skin peeling, or blisters in the mouth after using mesalazine.

If you experience severe or recurrent headache, vision disturbances, or ringing in the ears, contact your doctor immediately.

Additional Precautions

During treatment, your doctor may want to keep you under close medical supervision, and it may be necessary to perform regular blood and urine tests.

Kidney stones can occur with the use of mesalazine. Symptoms may include pain in the sides of the abdomen and blood in the urine. Make sure to drink enough fluids during treatment with mesalazine.

Severe skin reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SSJ), and toxic epidermal necrolysis (TEN), have been observed with mesalazine treatment. Stop taking mesalazine and seek medical attention immediately if you notice any of the symptoms related to these severe skin reactions described in section 4.

Mesalazine may cause a discoloration of the urine to a reddish-brown color after contact with sodium hypochlorite bleach in the toilet water. This is a chemical reaction between mesalazine and bleach and is harmless.

Other Medicines and Asacol 1g Suppositories

Tell your doctor if you are taking or using any of the following medicines, as their effects may change (interactions):

  • Azathioprine, 6-mercaptopurine, or thioguanine(medicines used to treat immune system disorders).
  • Certain medicines that inhibit blood clotting(medicines for thrombosis or to thin the blood, e.g., warfarin).

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Even so, it may be correct for you to use this medicine, and your doctor will decide what is suitable for you.

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

You should only use this medicine during pregnancy if your doctor tells you to.

You should only use this medicine during breastfeeding if your doctor tells you to, as the medicine may be excreted in breast milk.

Driving and Using Machines

This medicine is not expected to affect your ability to drive or use machines.

3. How to Use Asacol 1 g Suppositories

Follow the instructions for administration of this medicine exactly as told by your doctor. If you are unsure, ask your doctor or pharmacist.

Method of Administration

This medicine can only be used rectally, so it must be inserted into the anus. DO NOT swallow it.

Dosage

Adults and Elderly

For the treatment of acute ulcerative proctitis, the recommended dose is one mesalazine suppository once daily, at bedtime.

The dose will be adjusted by your doctor according to your disease.

Use in Children

There is limited experience and documentation of the effect in children.

Duration of Treatment

Your doctor will decide how long you need to continue treatment with this medicine. This will depend on your disease.

To get the most benefit from this medicine, you should use mesalazine regularly and constantly, as indicated.

If you think this medicine is too strong or too weak, talk to your doctor.

If you use more Asacol 1 g Suppositories than you should

Contact your doctor if you have any doubts so that they can decide what to do.

If you use too much mesalazine at one time, just take the next dose as prescribed.

Do not use a smaller amount.

If you forget to use Asacol 1g Suppositories

If you forget to use this medicine, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Use the next dose at the usual time. Do not use a double dose to make up for forgotten doses.

If you stop using Asacol 1g Suppositories

Do not stop using this medicine until you talk to your doctor.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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Discuss your symptoms and treatment with a doctor online.

4. Possible Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

All medicines can cause allergic reactions, although serious allergic reactions are very rare. If you get any of the following symptoms after using this medicine, you should contact your doctor immediately:

  • Allergic skin rash
  • Reddish patches, or circular or coin-shaped patches on the chest, often with central blisters, skin peeling, ulcers in the mouth, throat, nose, genitals, and eyes, generalized rash, fever, and swollen lymph nodes. These severe skin rashes are often preceded by fever or flu-like symptoms
  • Fever
  • Difficulty breathing

Tell your doctor immediatelyif you experience severe or recurrent headache, vision disturbances, or ringing in the ears. These could be symptoms of increased pressure inside your skull (idiopathic intracranial hypertension) (frequency not known [cannot be estimated from the available data]).

If you experience a marked worsening of your general health, especially if accompanied by fever and/or sore throat and mouth, stop using these suppositories andcontact your doctor immediately. These symptoms could, very rarely, be due to a reduction in the number of white blood cells in the blood (a disease called agranulocytosis), which can make you more prone to developing a serious infection. A blood test can confirm if your symptoms are due to an effect of this medicine on your blood.

The following side effects have also been reported by patients using mesalazine:

Rare side effects (may affect up to 1 in 100 patients):

  • Abdominal pain, diarrhea, flatulence, nausea, and vomiting, constipation
  • Headache, dizziness
  • Chest pain, difficulty breathing, or swelling of the limbs due to an effect on the heart
  • Increased sensitivity of the skin to sunlight and ultraviolet light (photosensitivity)

Very rare side effects(may affect up to 1 in 10,000 patients)

  • Changes in kidney function, sometimes with swelling of the limbs or pain in the side
  • Severe abdominal pain due to acute inflammation of the pancreas
  • Fever, sore throat, or malaise due to changes in the blood count
  • Shortness of breath, cough, wheezing, spots on the lungs visible on X-rays due to allergic and/or inflammatory lung diseases
  • Severe diarrhea and abdominal pain due to an allergic reaction to this medicine in the intestine
  • Skin rash or inflammation
  • Muscle and joint pain
  • Jaundice or abdominal pain due to liver and bile duct disorders
  • Hair loss and development of baldness
  • Numbness and tingling in hands and feet (peripheral neuropathy)
  • Reversible decrease in semen production

Unknown frequency side effects(frequency cannot be estimated from the available data)

  • Kidney stones and associated kidney pain (see also section 2)

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Asacol 1 g Suppositories

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the blister and on the carton after 'EXP'. The expiry date is the last day of the month stated.

Store below 30°C.

Store in the original package to protect from light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help protect the environment.

6. Contents of the pack and further information

Composition of Asacol 1g Suppositories

  • The active substance is mesalazine, and one suppository of this medicine contains 1 g of mesalazine.
  • The other component is hard fat.

Appearance of the product and pack contents

This medicine is suppositories in the shape of a torpedo, light beige in color.

This medicine is available in boxes of 10, 20, 30, 60, or 90 suppositories.

Not all pack sizes may be marketed.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder:

Tillotts Pharma Spain, S.L.U.

Travessera de Gràcia 58, 5º 3ª

08006 Barcelona

Spain

Manufacturer:

Tillotts Pharma GmbH

Warmbacher Strasse 80

79618 Rheinfelden

Germany

This medicine is authorised in the Member States of the European Economic Area under the following names:

Czech Republic, Denmark, Finland, Germany, Iceland, Norway, Spain, Sweden: Asacol.

Estonia, Latvia, Lithuania: Yaldigo

France: Fivasa

Ireland: Asacolon

Greece, Netherlands: Kiudro

Date of last revision of this leaflet:May 2025

Other sources of information

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.es/

Online doctors for ASACOL 1 G SUPPOSITORIES

Discuss questions about ASACOL 1 G SUPPOSITORIES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

5.0 (41)
Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
  • Metabolic syndrome – obesity, lipid disorders, insulin resistance.
Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
  • Respiratory infections – cough, colds, bronchitis.
  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
  • Cancer prevention – screening strategies and risk assessment.
  • Holistic approach – symptom relief, complication prevention, and quality of life improvement.
Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Doctor

Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
  •  Musculoskeletal system (MSK)
  •  Angiography
  •  Abdomen and pelvis
  •  Soft tissues

Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

Areas of expertise:

  • Endocrinology: diabetes type 1 and type 2, prediabetes, thyroid disorders, metabolic syndrome, hormonal imbalance.
  • Obesity medicine: structured weight management plans, nutritional counselling, obesity-related health risks.
  • Gastroenterology: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), liver and biliary conditions.
  • Pediatric care: infections, respiratory symptoms, digestive issues, growth and development monitoring.
  • General surgery support: pre- and post-surgical consultations, wound care, rehabilitation.
  • Pain management: chronic and acute pain, back pain, joint pain, post-traumatic pain syndromes.
  • Cardiovascular health: hypertension, cholesterol control, risk assessment for heart disease.
  • Preventive medicine: regular check-ups, health screenings, long-term management of chronic conditions.

Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
  • Food and drug allergies, skin rashes, angioedema.
  • Atopic dermatitis, urticaria, contact allergies.
  • Allergen-specific immunotherapy (AIT) – initiation and ongoing management.
  • Abdominal pain, bloating, changes in bowel habits, nausea, heartburn.
  • High blood pressure and adjustment of baseline antihypertensive therapy.
  • Hyperlipidaemia and elevated cholesterol.
  • Cough, nasal congestion, fever, sore throat.
  • Anaemia, including iron deficiency and related conditions.
  • Other issues related to allergology and internal medicine.

During consultations, Dr. Nazarchuk takes a thorough, structured approach — analysing symptoms, identifying potential causes, and helping patients make informed decisions. Whether treatment, further investigation, or monitoring is needed, he explains each step clearly so you understand your health and how best to manage it.

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€55
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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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€280

Frequently Asked Questions

Is a prescription required for ASACOL 1 G SUPPOSITORIES?
ASACOL 1 G SUPPOSITORIES requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ASACOL 1 G SUPPOSITORIES?
The active ingredient in ASACOL 1 G SUPPOSITORIES is mesalazine. This information helps identify medicines with the same composition but different brand names.
How much does ASACOL 1 G SUPPOSITORIES cost in pharmacies?
The average pharmacy price for ASACOL 1 G SUPPOSITORIES is around 45.13 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures ASACOL 1 G SUPPOSITORIES?
ASACOL 1 G SUPPOSITORIES is manufactured by Tillotts Pharma Spain S.L.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ASACOL 1 G SUPPOSITORIES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ASACOL 1 G SUPPOSITORIES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ASACOL 1 G SUPPOSITORIES?
Other medicines with the same active substance (mesalazine) include ASACOL 1600 mg GASTRO-RESISTANT TABLETS, ASACOL 400 mg GASTRO-RESISTANT TABLETS, ASACOL 800 MG GASTRO-RESISTANT TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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