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ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS

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About the medicine

How to use ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

Artific 3.20 mg/ml eye drops, solution in single-dose container

Hypromellose

Read the package leaflet carefully before starting to use this medicine because it contains important information for you.

It contains information that is important for you.

Follow the administration instructions of the medicine contained in this package leaflet or as indicated by your doctor, pharmacist, or nurse.

Keep this package leaflet, as you may need to read it again.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor, pharmacist, or nurse, even if they are side effects not listed in this package leaflet. See section 4.
  • You should consult a doctor if it worsens or does not improve after 7 days.

Contents of the Package Leaflet

  1. What Artific is and what it is used for
  2. What you need to know before using Artific
  3. How to use Artific
  4. Possible side effects
  5. Storage of Artific
  6. Contents of the pack and further information

1. What Artific is and what it is used for

Artific is a medicine that belongs to the group of artificial tears.

Artific is indicated for the symptomatic relief of irritation and dryness of the eyes.

You should consult a doctor if it worsens or does not improve after 7 days.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before using Artific

Do not use Artific

If you are allergic to hypromellose or any of the other components of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to use Artific.

If irritation, pain, redness, or changes in vision occur, or if you think your condition is worsening, stop using this medicine and consult your doctor or pharmacist.

Using Artific with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicine.

No interactions with other medicines have been described to date in intraocular application.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you might be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

There is no experience regarding the safety of this product during pregnancy or breastfeeding.

Driving and using machines

No effects on the ability to drive or use machines have been described with the use of Artific.

Artific contains sodium phosphate dodecahydrate and sodium dihydrogen phosphate dihydrate

This medicine contains 0.068 mg of phosphates in each drop, which is equivalent to 1.84 mg/ml.

If you have severe damage to the transparent layer of the front of the eye (cornea), treatment with phosphates may, in very rare cases, cause blurred vision due to calcium accumulation.

3. How to use Artific

Follow the administration instructions of this medicine exactly as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

Artific should only be used via the ocular route, as eye drops.

The recommended dose is one drop in the eye 3 to 5 times a day, or more frequently if necessary. The treatment of dry eye syndrome requires an individualized dosing regimen.

This medicine does not contain preservatives; therefore, wearers of soft contact lensesdo not need to remove them before administering this medicine.

  1. Separate a single-dose container from the blister pack.
  2. Turn the cap and open the container.
  3. Instill the eye drops into the eye by placing the container perpendicular to it.

Do not store after opening. Discard the remaining contents of the single-dose container after each application.

If you use more Artific than you should

If you have used more Artific than you should, consult your doctor or pharmacist immediately.

No adverse effects due to ocular overdose are known, and no overdose effects are expected with ocular administration.

In case of overdose or accidental ingestion, go immediately to a medical center or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to use Artific

Do not use a double dose to make up for forgotten doses.

If you stop using Artific

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

You may experience the following side effects:

Uncommon (between 1 and 10 in every 1000 patients): burning sensation, blurred vision, and sticky eyelids.

Reporting side effects:

If you experience any side effects, consult your doctor or pharmacist, even if they are possible side effects not listed in this package leaflet. You can also report them directly through the Spanish Medicines and Healthcare Products Agency's website: https://www.notificaram.es.

By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Artific

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the container after CAD. The expiry date is the last day of the month indicated.

Discard after use. Do not reuse.

Do not store above 25°C.

Medicines should not be disposed of via wastewater or household waste. Place the containers and medicines you no longer need in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the containers and medicines you no longer need. This will help protect the environment.

6. Contents of the pack and further information

Composition of Artific

  • The active ingredient is hypromellose (methocel F4M). 1 ml of solution contains 3.20 mg of hypromellose.
  • The other ingredients are: sodium phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, sorbitol (E420), and water for injection.

Appearance and packaging of the product

Artific is a clear, transparent, and particle-free solution.

It is presented in boxes of 30 single-dose containers of 0.5 ml.

Marketing authorization holder and manufacturer

Marketing authorization holder

Bausch & Lomb S.A.

Avda. Valdeparra, 4

28108 – Alcobendas, Madrid

Spain

Manufacturer

Dr. Gerhard Mann Brunsbütteler Damm 165/173

13581 Berlin

Germany

Date of the last revision of this package leaflet: November 2020

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS

Discuss questions about ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
  • allergic rhinitis and chronic nasal symptoms
  • asthma and breathing difficulties
  • food and medication allergies
  • urticaria, atopic dermatitis and skin reactions
  • recurrent infections in children
  • sports-related health questions
  • general family medicine concerns

Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Frequently Asked Questions

Is a prescription required for ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS?

ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS?

The active ingredient in ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS is artificial tears and other indifferent preparations. This information helps identify medicines with the same composition but different brand names.

Who manufactures ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS?

ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS is manufactured by Bausch & Lomb S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to ARTIFIC 3.20 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS?

Other medicines with the same active substance (artificial tears and other indifferent preparations) include ACUOLENS 3 mg/ml + 5.5 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS, ARTIFIC 3.20 mg/ml EYE DROPS SOLUTION, CARMELOSE QUALIGEN 5 mg/ml EYE DROPS IN SINGLE-DOSE CONTAINERS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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