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APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS

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This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: information for the user

Apulco CoHe 0.28%/9.5% compressed medical gas

Carbon monoxide (CO), helium (He)

Read this leaflet carefully before starting to use this medicine, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again. If you have any questions, consult your doctor.
  • This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What Apulco CoHe is and what it is used for
  2. What you need to know before starting to use Apulco CoHe
  3. How to use Apulco CoHe
  4. Possible side effects
  5. Storage of Apulco CoHe
  6. Package contents and additional information

1. What Apulco CoHe is and what it is used for

Apulco CoHe is a medical gas that is only used for diagnostic purposes. It is used during diagnostic tests of lung function: determination of diffusion capacity/transfer factor.

Doctor consultation

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Discuss your symptoms and treatment with a doctor online.

2. What you need to know before starting to use Apulco CoHe

Do not use Apulco CoHe:

Unless your doctor has asked you to undergo lung function tests.

Warnings and precautions

Consult your doctor before starting to use Apulco CoHe for lung function tests.

Using Apulco CoHe with other medicines

Tell your doctor if you are using, have recently used, or may need to use any other medicine.

Using Apulco CoHe with food, drinks, and alcohol

When using Apulco CoHe, you should not be in a state that would prevent you from performing the lung function test correctly according to your doctor's or medical staff's instructions.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before inhaling Apulco CoHe.

Driving and using machines

Using Apulco CoHe during lung function tests should not affect your ability to drive and use machines.

3. How to use Apulco CoHe

Inhale Apulco CoHe only during diagnostic tests of lung function and exactly as your doctor or medical staff has instructed you. If in doubt, consult your doctor again.

Only your doctor or medical staff should decide the duration of the diagnostic lung function test and the frequency of repeating the test.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

During inhalation of Apulco CoHe in lung function tests, side effects such as dizziness, chest pain, and a feeling of disorientation may occur, although this is very rare. If any of these symptoms appear while using the medical gas, you should stop inhaling Apulco CoHe immediately and receive medical treatment.

A blood sample may need to be taken for blood gas analysis after inhaling Apulco CoHe.

Reporting side effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medicines Surveillance System for Human Use: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Apulco CoHe

Keep out of sight and reach of children.

Gas cylinders should be stored indoors and protected from adverse weather conditions.

Do not use this medical gas after the expiration date shown on the label.

Do not dispose of this medical gas. Return it to the supplier. This will help protect the environment.

6. Package contents and additional information

What Apulco CoHe contains

The active ingredients are carbon monoxide and helium.

The other ingredients are nitrogen and oxygen.

Appearance of Apulco CoHe and package contents

Apulco CoHe is a colorless and odorless gas compressed in aluminum gas cylinders.

The body of the gas cylinder is white and the top of the gas cylinder is bright green.

Package sizes in liters (200 bar): 5L, 10L, 20L, and 40L.

Capacity in liters

Filling pressure (bar)

Liters of gas

m3of gas at 1 bar and 15°C

5

200

904

0.904

10

200

1808

1.808

20

200

3615

3.615

40

200

7231

7.231

Marketing authorization holder

S.E. de Carburos Metálicos S.A.

Avda. de la Fama, 1

08940 Cornella de Llobregat

Spain

Manufacturer

S.E. de Carburos Metálicos S.A.

Pol. Nord-Este C-35, km 59

08470 Sant Celoni

Spain

This medicine is authorized in the Member States of the European Economic Area under the following names:

Netherlands: Apulco CoHe.

Germany: Apulco CoHe.

Spain: Apulco CoHe.

Portugal: Apulco CoHe.

Slovenia: Apulco CoHe.

Czech Republic: Apulco CoHe.

Date of last revision of this leaflet: March 2021

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es.

Online doctors for APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS

Discuss questions about APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Dmytro Horobets

Family medicine 7 years exp.

Dr. Dmytro Horobets is a licensed family medicine physician in Poland, specialising in endocrinology, diabetology, obesity management, gastroenterology, pediatrics, general surgery, and pain medicine. He offers online consultations for adults and children, providing personalised medical support for a wide range of acute and chronic health concerns.

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Dr. Horobets combines evidence-based medicine with a patient-centred approach. He carefully evaluates each patient’s medical history and symptoms, offering clear explanations and structured treatment plans adapted to individual needs.

Whether you need help managing diabetes, tackling weight-related health issues, interpreting lab results, or receiving general family medicine support, Dr. Horobets provides professional online care tailored to your specific health goals.

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Doctor

Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques. For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance. Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults. In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions. Patients commonly seek his care for: 

  • seasonal and perennial allergies
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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.

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Doctor

Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
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  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
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  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
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Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Doctor

Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

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Bulat Garipov

General medicine 15 years exp.

Dr. Bulat Garipov is a radiologist with more than 15 years of experience, specializing in magnetic resonance imaging (MRI). Throughout his professional career, he has worked in leading diagnostic imaging centers, both in on-site practice and teleradiology, which has allowed him to develop a broad and versatile approach to radiology.

Over the years, he has gained solid experience in interpreting MRI studies in various areas, including:

  •  Neuroimaging
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Additionally, Dr. Garipov is open to new collaboration opportunities in radiology and teleradiology projects. He offers his expertise in MRI, providing both first and second readings of studies, as well as advanced image interpretation, ensuring accurate and high-quality diagnostics.

You could consult Dr. Bulat Garipov in cases where accurate interpretation of MRI studies or a second expert opinion is required. His expertise is especially valuable in cases of suspected neurological conditions, back and joint pain, vascular disorders, as well as in the diagnosis of abdominal and pelvic diseases. The doctor also provides support in complex or unclear clinical situations, including the review of previously performed studies, which helps improve diagnostic accuracy and determine the optimal treatment strategy. A teleradiology format is available, allowing you to receive a professional opinion remotely.

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Frequently Asked Questions

Is a prescription required for APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS?
APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS?
The active ingredient in APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS is Other diagnostic agents. This information helps identify medicines with the same composition but different brand names.
Who manufactures APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS?
APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS is manufactured by Sociedad Española De Carburos Metalicos S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to APULCO COHE 0.28%/9.5% MEDICINAL COMPRESSED GAS?
Other medicines with the same active substance (Other diagnostic agents) include APULCO ACOMETH 0.3%/0.3%/0.3% MEDICINAL COMPRESSED GAS, APULCO COHEMAX 0.28%/14% MEDICINAL COMPRESSED GAS, ICOMAS 0.3%/0.3%/0.3% MEDICINAL COMPRESSED GAS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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