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APOGAR 5MG/5MG LOZENGES

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About the medicine

How to use APOGAR 5MG/5MG LOZENGES

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: Information for the user

Apogar 5 mg/5 mg lozenges

Chlorhexidine dihydrochloride/Benzocaine

Read the entire leaflet carefully before starting to take this medication, as it contains important information for you.

Follow the administration instructions for the medication contained in this leaflet or as indicated by your doctor or pharmacist.

  • Keep this leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet.
  • You should consult your doctor if your condition worsens or does not improve after 2 days.

Contents of the leaflet

  1. What Apogar is and what it is used for
  2. What you need to know before taking Apogar
  3. How to take Apogar
  4. Possible side effects
  5. Storage of Apogar
  6. Package contents and additional information

1. What Apogar is and what it is used for

The active ingredients of this medication work by combining the antiseptic and disinfectant action of chlorhexidine with the local anesthetic action of benzocaine.

This medication is used for the symptomatic local and temporary relief of mild mouth and throat infections that occur with pain and without fever, such as: throat irritation, hoarseness, small mouth sores, from 6 years of age.

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2. What you need to know before taking Apogar

Do not take Apogar

  • if you are allergic to the active ingredients or to any of the other components of this medication, including those listed in section 6.
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A

Consult your doctor or pharmacist before starting to take this medication:

  • if you do not tolerate other local anesthetics such as para-aminobenzoic acid (PABA), parabens, or paraphenylenediamine (a hair dye component),
  • if you are an elderly patient or your immune system is weakened, you may need lower doses; in case of doubt, consult a doctor,
  • if you have a severe or extensive injury in the mouth,
  • if you have periodontitis (gum disease), as chlorhexidine may cause an increase in supragingival calculus,
  • it is recommended to maintain good oral hygiene to reduce plaque accumulation and possible tooth discoloration that may be caused by chlorhexidine,
  • do not take higher doses than recommended in section 3 (How to take Apogar).

Use of other medications

Tell your doctor or pharmacist if you are using or have recently used other medications, including those purchased without a prescription.

Although they are not described in the recommended conditions of use, do not use with other medications for mouth or throat application without consulting your doctor or pharmacist.

This is especially important in the case of:

  • Other mouth or throat antiseptics.
  • Cholinesterase inhibitor medications (medications for Alzheimer's disease).
  • Sulfonamides (used for infections).

Anionic compounds and suspending agents, common components of toothpastes, reduce the effectiveness of chlorhexidine, so the mouth should be rinsed well after using toothpaste.

Interference with diagnostic tests

This medication may interact with the pancreatic function test that uses bentiromide. Do not take this medication at least three days before the test and inform your doctor.

Children and adolescents

This medication should be administered to children over 6 years of age. For the administration form in children over 6 years of age, see section 3.

How to take Apogar

It should be used with caution as methemoglobinemia (difficulty breathing, dizziness, fatigue, weakness) may occur.

Use of Apogar with other medications

Tell your doctor or pharmacist if you are taking, have recently taken, or may need to take any other medication.

Although they are not described in the recommended conditions of use, do not use with other medications for mouth or throat application without consulting your doctor or pharmacist.

This is especially important in the case of:

  • Other mouth or throat antiseptics (disinfectants).
  • Cholinesterase inhibitor medications (medications for Alzheimer's disease).
  • Sulfonamides (used for infections).

Anionic compounds and suspending agents, common components of toothpastes, reduce the effectiveness of chlorhexidine, so the mouth should be rinsed well after using toothpaste.

Pregnancy and breastfeeding

If you are pregnant, breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medication.

Taking medications during pregnancy can be hazardous to the embryo or fetus and should be monitored by your doctor.

Driving and using machines

No cases have been reported that affect the ability to drive or use machines.

3. How to take Apogar

Follow the administration instructions for this medication as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist.

The recommended dose is:

Adults, adolescents, and children over 6 years of age

1 lozenge every 2 or 3 hours, dissolving it slowly in the mouth.

Do not take more than 8 lozenges in 24 hours (1 day).

Dissolve the lozenge slowly in the mouth without chewing or swallowing.

Elderly patients

Elderly patients and more debilitated patients may be more sensitive to benzocaine, so lower concentrations of this medication may be needed.

This medication is for buccopharyngeal use, so the lozenges should be dissolved slowly in the mouth without chewing or swallowing, as its action is local and only occurs when the product is in direct contact with the affected area.

Always use the lowest effective dose.

If you notice that your symptoms worsen or persist for more than 2 days after starting treatment or if you develop a fever, headache, nausea, or vomiting, you should consult your doctor as soon as possible.

If you take more Apogar than you should

Signs of overdose are: slurred speech, numbness, staggering gait, blurred or double vision, dizziness, excitement, or convulsions, ringing in the ears, increased sweating. A decrease in blood pressure may also occur.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately, or call the Toxicology Information Service, phone 91 562 04 20, indicating the medication and the amount ingested.

If you forget to take Apogar

Do not take a double dose to make up for forgotten doses.

If you have any other questions about the use of this medication, ask your doctor or pharmacist.

4. Possible side effects

Like all medications, Apogar can cause side effects, although not everyone will experience them.

The most characteristic adverse reactions due to benzocaine are:

Tooth discoloration may appear, especially in people with plaque accumulation on their teeth. This alteration of tooth color is not permanent and can be eliminated through a dental cleaning. The color of fillings may also be altered, in which case this discoloration may be permanent.

Alteration in taste perception may occur.

Irritation in the mouth or irritation of the tip of the tongue or numbness of the tongue may occur, which are usually transient, lack of sensitivity in the mouth, stomatitis (inflammation of the oral mucosa), desquamation of the mucosa, burning sensation in the mucosa, change in taste perception; discoloration of teeth, tongue, fillings, and dentures; increased plaque, as well as hypersensitivity reactions such as urticaria, angioedema (swelling of certain areas of the skin), anaphylactic reaction, or anaphylactic shock, mainly due to chlorhexidine.

Inflammation of the parotid gland has also been reported.

Some cases of methemoglobinemia caused by benzocaine have been reported, with symptoms such as difficulty breathing, cyanosis (bluish discoloration of the skin and mucous membranes), altered mental state, headache, fatigue, difficulty exercising, dizziness, and loss of consciousness.

In some cases, this medication may cause irritation in the mouth or irritation of the tip of the tongue, which are usually transient, as well as allergic reactions to chlorhexidine or benzocaine.

Reporting side effects

If you experience any of the side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medication Surveillance System for Human Use: www.notificaRAM.es. By reporting side effects, you can contribute to providing more information on the safety of this medication.

If you consider that any of the side effects you are experiencing are serious or if you notice any side effect not mentioned in this leaflet, inform your doctor or pharmacist.

5. Storage of Apogar

Keep this medication out of the sight and reach of children.

Store below 30°C.

Do not use this medication after the expiration date shown on the packaging, after "EXP". The expiration date is the last day of the month indicated.

Medications should not be disposed of through wastewater or household waste. Deposit the packaging and any unused medications at the SIGRE collection point in your pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medications. This will help protect the environment.

6. Package contents and additional information

Composition of Apogar

The active ingredients are chlorhexidine dihydrochloride and benzocaine.

Each lozenge contains 5 mg of chlorhexidine dihydrochloride and 5 mg of benzocaine.

The other components (excipients) are: mannitol (E-421), microcrystalline cellulose (E-460), povidone, magnesium stearate, sodium cyclamate, sodium saccharin (E-954), menthol flavor, and orange flavor.

Appearance of the product and package contents

Apogar are lozenges with an orange flavor, white-yellowish in color, rounded, and scored on one side.

Aluminum blister pack coated with PVDC and layered with PVC/PE/PVDC. Available in packages of 20 lozenges.

Marketing authorization holder and manufacturer

Marketing authorization holder

Aurovitas Spain, S.A.U.

Avda. De Burgos, 16-D

28036 Madrid

Spain

Manufacturer

Laboratorios Alcalá Farma, S.L.

Avenida de Madrid 82

28802 Alcalá de Henares (Madrid)

Date of the last revision of this leaflet:June 2025

Detailed information about this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for APOGAR 5MG/5MG LOZENGES

Discuss questions about APOGAR 5MG/5MG LOZENGES, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Svetlana Kolomeeva

Cardiology 18 years exp.

Dr. Svetlana Kolomeeva is a general practitioner and internal medicine doctor providing online consultations for adults. She helps patients manage acute symptoms, chronic conditions, and preventive care. Her clinical focus includes cardiovascular health, hypertension control, and managing symptoms like fatigue, weakness, sleep issues, and overall low energy.

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Dr Kolomeeva combines clinical expertise with personalised care. She clearly explains diagnoses, guides patients through symptoms and treatment options, and provides actionable plans. Her consultations are designed not only to address current complaints but also to stabilise chronic conditions and prevent future complications. She supports patients through every stage of care – from first symptoms to ongoing health management.

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Sergey Ilyasov

Psychiatry 7 years exp.

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

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Psychiatry 7 years exp.

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Alexander Nazarchuk

Allergology 7 years exp.

Dr. Alexander Nazarchuk is a physician specialising in allergology and internal medicine. He provides online consultations for adults, following the principles of evidence-based medicine — no outdated treatments or unnecessary tests, with clear explanations and a personalised approach. He helps patients with a wide range of allergic and therapeutic conditions, from common day-to-day complaints to complex cases involving allergies, gastrointestinal issues, cardiovascular concerns, respiratory symptoms, and more.

You can consult Dr. Nazarchuk for:

  • Test interpretation and guidance on diagnostic plans.
  • Allergic rhinitis, hay fever, bronchial asthma (including severe cases).
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Frequently Asked Questions

Is a prescription required for APOGAR 5MG/5MG LOZENGES?
APOGAR 5MG/5MG LOZENGES does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
Who manufactures APOGAR 5MG/5MG LOZENGES?
APOGAR 5MG/5MG LOZENGES is manufactured by Aurovitas Spain, S.A.U.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of APOGAR 5MG/5MG LOZENGES online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether APOGAR 5MG/5MG LOZENGES is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to APOGAR 5MG/5MG LOZENGES?
Other medicines with the same active substance () include BETADINE 10 mg/ml MOUTH RINSE SOLUTION, BETADINE BUCAL 100 mg/mL ORAL SOLUTION, BUCOMAX WITH LIDOCAINE LOZENGES MINT FLAVOR. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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