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AMOXICILLIN ARDINE 500 mg TABLETS

This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use AMOXICILLIN ARDINE 500 mg TABLETS

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: information for the user

Amoxicilina Ardine 500 mg tablets EFG

amoxicillin

Read the entire leaflet carefully before starting to take this medicine, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any doubts, consult your doctor or pharmacist.
  • This medicine has been prescribed to you (or your child) and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor or pharmacist, even if they are side effects not listed in this leaflet. See section 4.

Contents of the leaflet:

  1. What is Amoxicilina Ardine and what is it used for
  2. What you need to know before taking Amoxicilina Ardine
  3. How to take Amoxicilina Ardine
  4. Possible side effects
  5. Storage of Amoxicilina Ardine
  6. Contents of the pack and additional information

1. What is Amoxicilina Ardine and what is it used for

What is Amoxicilina Ardine

Amoxicilina Ardine is an antibiotic. The active ingredient is amoxicillin. This medicine belongs to a group of medicines called "penicillins".

Antibiotics are used to treat bacterial infections and are not effective against viral infections such as the flu or the common cold.

It is essential that you follow the instructions regarding dosage, administration interval, and treatment duration indicated by your doctor.

Do not store or reuse this medicine. If you have any leftover antibiotic after finishing the treatment, return it to the pharmacy for proper disposal. Do not throw medicines down the drain or in the trash.

What is Amoxicilina Ardine used for

Amoxicilina Ardine is used to treat infections caused by bacteria in different parts of the body. Amoxicilina Ardine can also be used in combination with other medicines to treat stomach ulcers.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before taking Amoxicilina Ardine

Do not take Amoxicilina Ardine:

  • if you are allergic to amoxicillin, penicillins, or any of the other ingredients of this medicine (listed in section 6).
  • if you have ever had an allergic reaction to any other antibiotic. This could include a skin rash or swelling of the face or throat.

Do not take Amoxicilina Ardine if any of the above points apply to you. If you are unsure, consult your doctor or pharmacist before taking Amoxicilina Ardine.

Warnings and precautions

Consult your doctor or pharmacist before taking Amoxicilina Ardine if:

  • you have infectious mononucleosis (fever, sore throat, swollen glands, and extreme fatigue)
  • you have kidney problems
  • you do not urinate regularly.

If you are unsure whether any of the above situations apply to you, inform your doctor or pharmacist before taking Amoxicilina Ardine.

Blood and urine tests

If you are having:

  • urine tests (glucose in urine) or blood tests for liver function
  • estriol tests (used during pregnancy to check if the baby is developing normally).

Inform your doctor or pharmacist that you are taking Amoxicilina Ardine. This is because Amoxicilina Ardine may affect the results of these types of tests.

Using Amoxicilina Ardine with other medicines

Inform your doctor or pharmacist if you are using, have recently used, or may need to use any other medicine.

  • If you are taking allopurinol (used for gout) with Amoxicilina Ardine, you may be more likely to experience a skin allergic reaction.
  • If you are taking probenecid (used to treat gout), your doctor may adjust the dose of Amoxicilina Ardine. Concomitant use of probenecid can reduce the excretion of Amoxicilina and is not recommended.
  • If you are taking anticoagulants (such as warfarin) with Amoxicilina Ardine, more blood tests may be necessary
  • If you are taking other antibiotics (such as tetracycline), Amoxicilina Ardine may be less effective.
  • If you are taking methotrexate (a medicine used to treat cancer and severe psoriasis), Amoxicilina Ardine may increase the risk of side effects. Penicillins can reduce the excretion of methotrexate and cause a potential increase in side effects.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Driving and using machines

Amoxicilina Ardine may have side effects and symptoms (such as allergic reactions, dizziness, and convulsions) that can make you unfit to drive.

Do not drive or operate machinery unless you feel well.

Amoxicilina Ardine contains glucose

This medicine contains glucose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

3. How to take Amoxicilina Ardine

Follow the administration instructions of this medicine exactly as indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

  • Add the tablet to a glass of water and stir well until it is evenly mixed. Swallow the mixture immediately. The tablet can also be swallowed whole.
  • Space the doses evenly throughout the day, at least 4 hours apart.

The usual dose is:

Children under 40 kg of weight

All doses are based on the child's body weight in kilograms.

  • Your doctor will tell you how much Amoxicilina Ardine to give to your baby or child.
  • The usual dose is 40 mg to 90 mg per kilogram of body weight per day, administered in two or three divided doses.
  • The maximum dose is 100 mg per kilogram of body weight per day.

Adults, elderly patients, and children over 40 kg of weight

The usual dose of Amoxicilina Ardine is 250 mg to 500 mg three times a day or 750 mg to 1 g every 12 hours, depending on the severity and type of infection.

  • Severe infections: 750 mg to 1 g, three times a day.
  • Urinary tract infection: 3 g twice a day, for one day.
  • Lyme disease (an infection caused by parasites called ticks): isolated erythema migrans (early stage - circular pink or red rash): 4 g per day; systemic manifestations (late stage - with more severe symptoms or when the disease spreads throughout the body): up to 6 g per day.
  • Stomach ulcers: a dose of 750 mg or a dose of 1 g twice a day for 7 days, with other antibiotics and medicines to treat stomach ulcers.
  • To prevent heart infection during surgery: the dose will vary depending on the type of surgery. Other medicines may be administered at the same time. Your doctor, pharmacist, or nurse can provide more details.
  • The maximum recommended dose is 6 g per day.

Kidney problems

If you have kidney problems, the dose may be lower than the usual dose.

If you take more Amoxicilina Ardine than you should

If you have taken more Amoxicilina Ardine than you should, the signs may be stomach upset (nausea, vomiting, or diarrhea) or crystals in the urine, which can be seen as cloudy urine or difficulty urinating. Talk to your doctor as soon as possible. Bring the medicine to show them. You can also call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to take Amoxicilina Ardine

  • If you forget to take a dose, take it as soon as you remember.
  • Do not take the next dose too soon, wait at least 4 hours before taking the next dose
  • Do not take a double dose to make up for forgotten doses.

How long to take Amoxicilina Ardine

  • Continue taking Amoxicilina Ardine for the time your doctor has indicated, even if you feel better. You need to take all the doses to overcome the infection. If some bacteria survive, they can cause the infection to recur.
  • Once you finish the treatment, if you continue to feel unwell, you should go back to see your doctor.

Thrush (a fungal infection of the moist parts of the body that can cause pain, itching, and white discharge) may appear if you take Amoxicilina Ardine for a long time. If this happens, consult your doctor.

If you take Amoxicilina Ardine for a long time, your doctor may perform additional tests to check that your kidneys, liver, and blood are working normally.

If you have any other doubts about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Stop taking Amoxicilina Ardine and go see a doctor immediately if you experience any of the following serious side effects - you may need urgent medical treatment:

The following side effects are very rare (may affect up to 1 in 10,000 people)

  • allergic reactions, the signs can include: itching of the skin or rash, swelling of the face, lips, tongue, body, or difficulty breathing. These can be serious and, in some cases, have been fatal
  • skin rash or flat red spots under the skin surface or bruising on the skin. This is due to inflammation of the blood vessel walls due to an allergic reaction. It can be associated with joint pain (arthritis) and kidney problems
  • a delayed allergic reaction may appear 7 to 12 days after taking Amoxicilina Ardine, some signs include: rashes, fever, joint pain, and swelling of the lymph nodes, especially under the arms
  • a skin reaction called 'erythema multiforme' in which you may develop: purple or reddish rashes with itching on the skin, especially on the palms of the hands or soles of the feet, swollen areas on the skin, soft tissues on the surface of the mouth, eyes, or genitals. You may have a fever and feel very tired
  • other serious skin reactions may include: change in skin color, lumps under the skin, blisters, pimples with pus, peeling, redness, pain, itching. These can be associated with fever, headache, and body pain
  • flu-like symptoms with skin rash, fever, gland inflammation, and abnormal blood test results (such as increased white blood cells (eosinophilia) and elevated liver enzymes) (drug reaction with eosinophilia and systemic symptoms (DRESS))
  • fever, chills, sore throat, or other signs of infection, or easy bruising. These can be signs of a problem with your blood cells
  • Jarisch-Herxheimer reaction that occurs during treatment with Amoxicilina Ardine for Lyme disease and causes fever, chills, headache, muscle pain, and skin rash
  • inflammation of the large intestine (colon) with diarrhea (sometimes with blood), pain, and fever
  • serious liver effects may occur. These are mainly associated with prolonged treatments, men, and the elderly. You should inform your doctor immediately if you have:
    • severe diarrhea with bleeding
    • blisters, redness, or bruising on the skin
    • dark urine or pale stools
    • yellowing of the skin and the whites of the eyes (jaundice). See also anemia below, which can cause jaundice.
  • Chest pain in the context of allergic reactions, which can be a symptom of allergy-induced heart attack (Kounis syndrome)
  • Drug-induced enterocolitis syndrome (DIES): DIES has been reported mainly in children receiving amoxicillin. It is a certain type of allergic reaction with the main symptom of repeated vomiting (1-4 hours after taking the medicine). Other symptoms may include abdominal pain, lethargy, diarrhea, and low blood pressure.
  • Crystals in the urine that cause acute kidney injury
  • A skin eruption with blisters arranged in a circle with a central crust or like a string of pearls (linear IgA disease).
  • Inflammation of the membranes surrounding the brain and spinal cord (aseptic meningitis)

These can occur during treatment or up to several weeks after.

If any of the above symptoms appear, stop taking the medicine and go see a doctor immediately.

Sometimes you may experience less severe skin reactions such as:

  • a moderate rash with itching (round, pink-red patches), swollen areas with a blister-like appearance on the forearms, legs, palms, hands, or feet. This is uncommon (may affect up to 1 in 100 people).

If you have any of these, talk to your doctor, as you will need to interrupt your treatment with Amoxicilina Ardine.

Other possible side effects are:

Common(may affect up to 1 in 10 people)

  • skin rash
  • diarrhea
  • nausea

Uncommon(may affect up to 1 in 100 people)

  • vomiting

Very rare(may affect up to 1 in 10,000 people)

  • thrush (fungal infection in the vagina, mouth, or skin folds), you can get treatment for thrush from your doctor or pharmacist
  • kidney problems
  • seizures (convulsions), observed in patients treated with high doses or with kidney problems
  • dizziness
  • hyperactivity
  • crystals in the urine, which can appear as cloudy urine or difficulty or discomfort urinating. Make sure to drink plenty of fluids to reduce the likelihood of these symptoms
  • discoloration of the teeth, which usually disappears with brushing (this has been reported in children)
  • the tongue may change color to yellow, brown, or black and may have a hairy appearance
  • a excessive breakdown of red blood cells that causes a type of anemia. The signs include: fatigue, headache, difficulty breathing, dizziness, paleness, and yellowing of the skin and the whites of the eyes
  • low white blood cell count
  • low number of cells involved in blood clotting
  • the blood may take longer than usual to clot. You may notice this if you have a nosebleed or cut yourself.

Reporting side effects

If you experience any side effects, consult your doctor, pharmacist, or nurse, even if they are side effects not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Amoxicilina Ardine

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiration date stated on the packaging after CAD. The expiration date is the last day of the month indicated.

Store in the original packaging to protect it from moisture.

Do not use this medicine if you notice visible signs of deterioration.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and any unused medicines in the SIGRE collection point at your usual pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Container Content and Additional Information

Composition of Amoxicilina Ardine

  • The active ingredient is Amoxicillin. Each tablet contains 500 mg of amoxicillin.
  • The other components are: Povidone, Sodium saccharin (E-954), Magnesium stearate, Sodium lauryl sulfate, Microcrystalline cellulose (E-460), and Raspberry flavor (contains glucose and corn starch).

Appearance of the Product and Container Content

Amoxicilina Ardine 500 mg tablets are white scored tablets. The score line is only for breaking and facilitating swallowing, but not for dividing into equal doses.

They are packaged in blisters in a box. It is available in packs of 20 and 30 tablets.

Marketing Authorization Holder and Manufacturer

Marketing Authorization Holder:

Laboratorio Reig Jofre, S.A.

Gran Capitán, 10

08970 Sant Joan Despí (Barcelona)

Manufacturer:

Laboratorio Reig Jofré, S.A.

Jarama, 111 (Polígono Industrial)

45007 (Toledo)

Date of the Last Revision of this Leaflet: January 2023.

Detailed and updated information on this medication is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

General Advice Regarding the Use of Antibiotics

Antibiotics are used to treat bacterial infections. They are not effective against viral infections.

Sometimes a bacterial infection does not respond to antibiotic treatment. One of the most common reasons for this is that the bacteria causing the infection are resistant to the antibiotic being taken. This means that the bacteria can survive or grow despite the antibiotic.

Bacteria can become resistant to antibiotics for many reasons. Using antibiotics properly can reduce the chances of bacteria becoming resistant to them.

When your doctor prescribes an antibiotic, it is only to treat your current illness. Paying attention to the following tips will help you prevent the appearance of resistant bacteria that can make the antibiotic not work:

  1. You should not take an antibiotic unless it has been specifically prescribed for you, and you should only use it for the infection for which it was prescribed.
  2. You should not take antibiotics that have been prescribed for other people, even if they had a similar infection to yours.
  3. You should not give antibiotics that have been prescribed for you to other people.
  4. If you still have antibiotic left after completing the treatment, return all unused medication to your pharmacy to ensure that the disposal requirements are met.

Online doctors for AMOXICILLIN ARDINE 500 mg TABLETS

Discuss questions about AMOXICILLIN ARDINE 500 mg TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Doctor

Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

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Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

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He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Chikeluo Okeke

General medicine 4 years exp.

Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

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Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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Jorge Correa Bellido

General medicine 7 years exp.

Dr. Jorge Correa Bellido is a Spanish physician who offers online consultations in Spanish and English. He graduated from the University of La Laguna and has a solid background in clinical practice and international research.

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Dr. Correa Bellido provides comprehensive care for a wide variety of medical conditions, including:

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He also treats infectious and allergic diseases, general health concerns, and provides guidance on prevention and healthy lifestyle habits.

His services include virtual consultations, diagnosis and management of acute and chronic diseases, prescription renewals, and personalized medical advice.

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Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

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Additional care areas:

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Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Antonio Cayatte

General medicine 44 years exp.

Dr Antonio Cayatte is a physician in General and Acute Medicine with over 30 years of experience across clinical care, medical research, and education. He offers online consultations for adults with a wide range of symptoms, both acute and chronic. His clinical background includes: 

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Dr Cayatte earned his degree from the University of Lisbon and taught internal medicine at Boston University School of Medicine. He holds active medical registrations in both Portugal and the UK and is a Fellow of the American Heart Association. Consultations are available in English and Portuguese. Patients value his clarity, professionalism, and balanced approach to evidence-based care.

Dr. Antonio Cayatte provides comprehensive care for a broad spectrum of common health concerns, including:

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Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

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Gastroenterology – Digestive health:
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General internal medicine and preventive care:
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.

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Frequently Asked Questions

Is a prescription required for AMOXICILLIN ARDINE 500 mg TABLETS?

AMOXICILLIN ARDINE 500 mg TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

What is the active substance in AMOXICILLIN ARDINE 500 mg TABLETS?

The active ingredient in AMOXICILLIN ARDINE 500 mg TABLETS is amoxicillin. This information helps identify medicines with the same composition but different brand names.

How much does AMOXICILLIN ARDINE 500 mg TABLETS cost in pharmacies?

The average pharmacy price for AMOXICILLIN ARDINE 500 mg TABLETS is around 2.5 EUR. Prices may vary depending on the manufacturer and dosage form.

Who manufactures AMOXICILLIN ARDINE 500 mg TABLETS?

AMOXICILLIN ARDINE 500 mg TABLETS is manufactured by Laboratorio Reig Jofre, S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Which doctors can assess the use of AMOXICILLIN ARDINE 500 mg TABLETS online?

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether AMOXICILLIN ARDINE 500 mg TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

How to buy AMOXICILLIN ARDINE 500 mg TABLETS in Spain?

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy AMOXICILLIN ARDINE 500 mg TABLETS in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

What are the alternatives to AMOXICILLIN ARDINE 500 mg TABLETS?

Other medicines with the same active substance (amoxicillin) include AMITRON 1 g POWDER FOR INJECTABLE SOLUTION, AMITRON 500 mg HARD CAPSULES, AMOXICILLIN ALMUS 1000 mg DISPERSIBLE TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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