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AMEXXINE 1 mg /Ml Eye Drops Solution

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Talk to a doctor about this medicine

Discuss your symptoms and possible next steps in a quick online consultation.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use AMEXXINE 1 mg/ml EYE DROPS SOLUTION

Contents of the leaflet

  1. Introduction
  2. What is Amexxine and what is it used for
  3. What you need to know before you start using Amexxine
  4. How to use Amexxine
  5. Possible side effects
  6. Storage of Amexxine
  7. Contents of the pack and further information

Introduction

Package Leaflet: Information for the User

Amexxine 1 mg/ml, eye drops solution

dexamethasone phosphate

Read this package leaflet carefully before you start using this medicine because it contains important information for you.

  • Keep this package leaflet, you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this package leaflet. See section 4.

Contents of the package leaflet

  1. What is Amexxine and what is it used for
  2. What you need to know before you start using Amexxine
  3. How to use Amexxine
  4. Possible side effects
  5. Storage of Amexxine
  6. Contents of the pack and further information

1. What is Amexxine and what is it used for

Amexxine is a multidose eye drop solution that contains the active substance dexamethasone. This substance is a corticosteroid that inhibits inflammatory symptoms.

Amexxine is indicated for the treatment of eye inflammation. The eye should not be infected (red eye, discharge, tearing, etc.); otherwise, this medicine should be combined with specific treatment for the infection (see section 2).

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before you start using Amexxine

Do not use Amexxine

  • If you have an eye infectionthat may be bacterial (acute purulent infection), fungal, viral (herpes virus, vaccinia virus, varicella-zoster virus) or amoebic.
  • If you have corneal damage(perforation, ulcers or lesions associated with incomplete healing).
  • If you have ocular hypertension(high intraocular pressure) caused by glucocorticosteroids (corticosteroid family).
  • If you are allergic(hypersensitive) to dexamethasone phosphate sodiumor any of the other components of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to use this medicine.

DO NOT INJECT, DO NOT INGEST

Avoid contact between the tip of the dispenser and the eye or eyelids.

  • Strict control by your ophthalmologist is required during the use of this medicine in any case and in particular:
    • In children and the elderly. More frequent ophthalmological monitoring is recommended.
    • If you have an eye infection, you should only use this medicine if the infection is being treated with an anti-infective.
    • If you have a corneal ulcer, do not use local treatment with dexamethasone or Amexxine, unless inflammation is the primary cause of delayed healing.
    • If you have high intraocular pressure or have previously experienced an increase in intraocular pressure after local steroid treatment, you are at risk of increased intraocular pressure if treated with Amexxine.
    • If you have glaucoma.
  • Children: Prolonged treatment should be avoided.
  • Severe allergic conjunctivitis: If you have severe allergic conjunctivitis that does not respond to usual treatment, use this medicine only for a short period.
  • Diabetes: If you are diabetic, inform your ophthalmologist.
  • Red eye: Do not use this medicine in case of undiagnosed red eye.
  • Contact lenses: You should avoid wearing contact lenses during treatment with this medicine.
  • Patients with a history of hypersensitivity to silver should not use this medicine, as the drops may contain traces of silver.

Consult your doctor if you experience swelling and weight gain around the trunk and face, as these are usually the first manifestations of a syndrome called Cushing's syndrome. Suppression of adrenal gland function may occur after intensive or prolonged treatment with dexamethasone. Consult your doctor before stopping treatment on your own. These risks are especially important in children and patients treated with a medicine called ritonavir or cobicistat.

Contact your doctor if you experience blurred vision or other visual disturbances.

Other medicines and Amexxine

If you are using any other medicine that is applied to the eye, you should wait 15 minutes between each application.

Tell your doctor if you are using ritonavir or cobicistat, as this may cause an increase in the amount of dexamethasone in the blood.

Calcium phosphate deposits in the cornea have been described during concomitant use of corticosteroids and local beta-blockers.

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

Pregnancy and breastfeeding

  • There is not enough data on the use of this medicine in pregnant women to assess the possible adverse effects.

For this reason, it is not recommended to use this medicine during pregnancy.

  • It is not known if this medicine is excreted in breast milk. However, the total dose of dexamethasone is low.

Therefore, this medicine can be used during breastfeeding.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.

Driving and using machines

As with all eye drops, temporary blurred vision or other visual disturbances may affect your ability to drive or use machines. Do not drive or use machines until your vision has returned to normal.

Amexxine contains phosphates

This medicine contains 2.177 mg of phosphates in each ml of solution.

If you have severe damage to the transparent layer of the front of the eye (the cornea), treatment with phosphates, in very rare cases, may cause cloudy patches on the cornea due to calcium.

3. How to use Amexxine

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

Dosage

Follow the instructions for administration of this medicine exactly as indicated by your doctor. If you are unsure, consult your doctor or pharmacist again.

The recommended dose is 1 drop, 4 to 6 times a day in the affected eye. In severe cases, treatment may be started with 1 drop every hour and should be reduced to 1 drop every 4 hours when a favorable response is observed. Gradual reduction of dose is recommended to avoid relapse.

  • In elderly patients: no dose adjustment is necessary.
  • In children: prolonged use should be avoided.

Method of administration

Ophthalmic route: this medicine is for administration in the eye.

Administration method

? Wash your handscarefully before using the product.

??Introduce one dropinto the affected eye, while tilting your head back slightly with your gaze directed upwards and pulling the lower eyelid down with your finger.

??Immediately after application, gently pressthe inner corner of the treated eye with your finger for a few minutes (to reduce the risk of systemic reactions and increase the penetration of the active substance into the eye).

? After use and before closing it again,the multidose container should be shaken once downwards, without touching the tip of the dropper, to eliminate any remaining liquid on the tip. This procedure is necessary to ensure the administration of the following drops.

Frequency of administration

4 to 6 times a day.

Duration of treatment

The duration of treatment may vary from several days to a maximum of 14 days.

If you use more Amexxine than you should

If too much product has been applied to the eye and you notice persistent irritation, rinse the eye with sterile water.

Contact your doctor or pharmacist immediately.

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicology Information Service, phone 91 562 04 20, indicating the medicine and the amount ingested.

If you forget to use Amexxine

Do not use a double dose to make up for forgotten doses.

If you stop treatment with Amexxine

Do not stop treatment abruptly. Always consult your doctor if you decide to stop treatment.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them:

Endocrine disorders:

Uncommon (may affect up to 1 in 100 people)

  • If used frequently, it is possible that the kidneys do not produce enough hormones (suppression of adrenal gland function). This may manifest as a decrease in blood sugar levels, dehydration, weight loss, and confusion.
  • Hormonal problems: excessive body hair growth (particularly in women), weakness and muscle wasting, purple striae on the skin, high blood pressure, irregular or absent menstrual periods, changes in protein and calcium levels in the body, delayed growth in children and adolescents, and swelling and weight gain of the body and face (Cushing's syndrome) (see section 2, "Warnings and precautions").

Eye disorders:

Very common: may affect more than 1 in 10 people

  • Increased intraocular pressure after 2 weeks of treatment.

Common: may affect up to 1 in 10 people

  • Discomfort, irritation, burning, itching, stinging, and blurred vision after application. These symptoms are usually transient and mild.

Uncommon: may affect up to 1 in 100 people

  • Allergic reactions and hypersensitivity to any of the components of the eye drops,
  • Delayed wound healing,
  • Clouding of the lens (cataract),

Infections,

  • Glaucoma.

Rare: may affect up to 1 in 10,000 people

  • Inflammation of the eye membranes (conjunctivitis),
  • Pupil dilation (mydriasis),
  • Swelling (facial edema),
  • Drooping eyelid (ptosis),
  • Inflammation of the iris (uveitis),
  • Corneal calcification,
  • Inflammation of the cornea (crystalline keratopathy),
  • Changes in corneal thickness,
  • Corneal edema,
  • Corneal ulceration,
  • Corneal perforation.
  • Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this package leaflet.

You can also report side effects directly through the Spanish Medicines Monitoring System for Human Use: www.notificaRAM.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Amexxine

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date stated on the multidose container after EXP. The expiry date is the last day of the month shown.

After first opening of the pouch: use the multidose container within 28 days of opening.

This medicine does not require any special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. This will help protect the environment.

6. Contents of the pack and further information

Composition of Amexxine

  • The active substance is dexamethasone phosphate. Each ml of solution contains 1 mg of dexamethasone phosphate (as dexamethasone phosphate sodium).
  • The other ingredients are sodium hydrogen phosphate dodecahydrate (E 399), sodium chloride, disodium edetate, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment), and water for injections.

Appearance of Amexxine and contents of the pack

Amexxine is a clear and transparent eye drop solution that comes in a multidose container. Each multidose container is a 11 ml white low-density polyethylene bottle (with dropper and screw cap) containing 6 ml of solution. The carton contains 1 or 3 multidose containers.

Not all pack sizes may be marketed.

Marketing authorisation holder and manufacturer

Pharmaselect International Beteiligungs GmbH

Ernst-Melchior-Gasse 20

1020 Wien, Austria.

This medicine has been authorised in the Member States of the European Economic Area under the following names:

Austria, Bulgaria, Denmark, Germany, Netherlands: Dexanova

Belgium: Darazon

Croatia, Hungary, Czech Republic: Darazur

Slovakia: Daraoc

Italy, Portugal: Amexzur

Date of last revision of this package leaflet:January 2023.

Detailed information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es.

Online doctors for AMEXXINE 1 mg/ml EYE DROPS SOLUTION

Discuss questions about AMEXXINE 1 mg/ml EYE DROPS SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(20)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70
Doctor
0.0(0)

Hocine Lokchiri

General medicine21 years of experience

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
Book a video appointment
€64

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Frequently Asked Questions

AMEXXINE 1 mg/ml EYE DROPS SOLUTION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in AMEXXINE 1 mg/ml EYE DROPS SOLUTION is dexamethasone. This information helps identify medicines with the same composition but different brand names.

AMEXXINE 1 mg/ml EYE DROPS SOLUTION is manufactured by Pharmaselect International Beteiligungs Gmbh. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether AMEXXINE 1 mg/ml EYE DROPS SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy AMEXXINE 1 mg/ml EYE DROPS SOLUTION in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (dexamethasone) include COLIRCUSI DEXAMETHASONE 1 mg/ml eye drops solution, DEXAFREE 1 mg/ml EYE DROPS IN SOLUTION IN SINGLE-DOSE CONTAINERS, DEXAMETHASONE POS 1 mg/ml EYE DROPS SOLUTION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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