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ADALGUR 500 mg/2 mg TABLETS

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About the medicine

How to use ADALGUR 500 mg/2 mg TABLETS

Translated with AI

This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

PACKAGE LEAFLET: INFORMATION FOR THE USER

Adalgur500 mg/2 mg tablets

Paracetamol / Tiocolchicoside

Read all of this leaflet carefully before you start taking this medicine, because it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

Contents of the pack

  1. What Adalgur is and what it is used for
  2. What you need to know before you take Adalgur
  3. How to take Adalgur
  4. Possible side effects
  5. Storage of Adalgur
  6. Contents of the pack and other information

1. What Adalgur is and what it is used for

Adalgur is an association of an analgesic (to reduce pain) and a muscle relaxant. It is used in adults and adolescents over 16 years of age as an adjunctive treatment for painful muscle contractions. It should be used for acute conditions related to the spine.

Doctor consultation

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2. What you need to know before you take Adalgur

Do not take Adalgur:

  • if you are allergic to paracetamol, tiocolchicoside, or any of the other ingredients of this medicine (listed in section 6).
  • if you have severe liver disease.
  • in case of paralysis or muscle weakness.
  • if you have a blood disease called severe hemolytic anemia.
  • if you are pregnant, may become pregnant, or think you may be pregnant (see section 2 "Pregnancy, breastfeeding, and fertility").
  • if you are breastfeeding (see section 2 "Pregnancy, breastfeeding, and fertility").
  • if you are a woman of childbearing age who is not using effective contraceptive methods (during treatment and for one month after stopping treatment).
  • if you are a man who does not use effective contraceptive measures (during treatment and for three months after stopping treatment).

Warnings and precautions

Strictly follow the dosage and treatment duration indicated in section 3. Do not take this medicine at high doses or for more than 7 days. This is because one of the products formed in your body when taking tiocolchicoside at high doses can damage some cells (abnormal number of chromosomes). This has been demonstrated in animal studies and laboratory studies. In humans, this type of cellular damage is a risk factor for cancer, fetal damage, and reduced male fertility. Consult your doctor if you have any questions.

Your doctor will inform you about all measures related to effective contraceptive methods and the potential risk of pregnancy.

During treatment with Adalgur, immediately inform your doctor if:

  • you have epilepsy or are at risk of seizures, as seizures can occur with the use of this medicine.
  • you have chronic alcoholism, as you should be careful not to take more than 2 g/day of paracetamol.
  • you have liver or kidney problems, including Gilbert's syndrome (mild jaundice),
  • you suffer from chronic malnutrition or are dehydrated
  • you have any heart or lung disease or suffer from anemia (reduced hemoglobin levels in the blood, due to or not due to a reduction in red blood cells) or have low levels of an enzyme in the blood called glucose-6-phosphate dehydrogenase.
  • you have asthma or have a history of asthma, and/or are sensitive to acetylsalicylic acid.

If you have severe diseases, such as severe renal failure or sepsis (when bacteria and their toxins circulate in the blood, causing damage to organs), or if you suffer from malnutrition, chronic alcoholism, or are also taking flucloxacillin (an antibiotic). A serious disease called metabolic acidosis (an anomaly in the blood and fluids) has been reported in patients in these situations when using paracetamol at regular doses for a prolonged period or when taking paracetamol with flucloxacillin. The symptoms of metabolic acidosis may include: severe breathing difficulties with deep and rapid breathing, drowsiness, feeling unwell (nausea) and vomiting.

Consuming alcoholic beverages can cause paracetamol to damage the liver.

If the pain persists for more than 3 days or worsens or other symptoms appear, treatment should be discontinued and a doctor consulted.

Children and adolescents

This medicine should not be given to children and adolescents under 16 years of age for safety reasons.

Using Adalgur with other medicines

Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines.

Other medicines and paracetamol

Tell your doctor or pharmacist if you are taking:

  • Oral anticoagulants (used to treat thromboembolic diseases)
  • Antiepileptics (used to treat epileptic seizures)
  • Antibiotics (chloramphenicol)
  • Oral contraceptives
  • Activated charcoal (used for diarrhea or gas treatment)
  • Metoclopramide and domperidone (used to prevent nausea and vomiting)
  • Diuretics (used to increase urine elimination)
  • Isoniazid (used to treat tuberculosis)
  • Lamotrigine (used to treat epilepsy)
  • Probenecid (used to treat gout)
  • Propranolol (used to treat hypertension, cardiac arrhythmias)
  • Rifampicin (used to treat tuberculosis)
  • Anticholinergics (used to relieve spasms or contractions of the intestine and bladder)
  • Zidovudine (used to treat HIV infections)
  • Colestyramine (used to decrease blood cholesterol levels)
  • Flucloxacillin (antibiotic), due to a serious risk of blood and fluid anomalies (called metabolic acidosis) that requires urgent treatment (see section 2).

Do not use with other analgesics (pain-relieving medicines) without consulting your doctor.

Interference with laboratory tests

If you are going to have any laboratory tests (including blood tests, urine tests, skin tests using allergens, etc.), inform your doctor that you are taking this medicine, as it may alter the results of these tests.

Taking Adalgur with food, drinks, and alcohol

Consuming alcohol can increase the liver toxicity of paracetamol.

Pregnancy, breastfeeding, and fertility

Do not take this medicine if:

  • you are pregnant, may become pregnant, or think you may be pregnant (see section 2 "Do not take Adalgur").
  • you are a woman of childbearing age who is not using adequate contraceptive methods (see section 2 "Do not take Adalgur").

This is because this medicine can harm the fetus.

Do not take this medicine if you are breastfeeding. This is because the medicine is excreted in breast milk (see section 2 "Do not take Adalgur").

Do not take this medicine if:

  • you are a man who does not use effective contraceptive methods (see section 2 "Do not take Adalgur").

This medicine may cause problems with male fertility, due to potential damage to sperm (abnormal number of chromosomes). These data are based on laboratory studies (see section 2 "Warnings and precautions").

Contraception in women and men

Women who may become pregnant should use an effective contraceptive method while taking Adalgur and for one month after stopping treatment.

Adalgur and its metabolites can cause harm to the fetus if used by pregnant women. If you are pregnant or become pregnant during treatment with Adalgur, consult a doctor immediately.

Men should use effective contraceptive methods and should be advised not to conceive children while taking Adalgur and for three months after stopping treatment (see section 2 "Do not take Adalgur").

Driving and using machines

You may feel drowsy with this medicine, so it is recommended that you do not drive or operate machinery until you have checked that this medicine does not affect you.

3. How to take Adalgur

Follow exactly the administration instructions of this medicine indicated by your doctor or pharmacist. In case of doubt, consult your doctor or pharmacist again.

Adults and adolescents over 16 years of age:

The recommended dose is 1 or 2 tablets per intake. Intakes can be repeated 2 to 4 times a day.

The maximum recommended single dose is 2 tablets per intake, and the minimum interval between each administration is 6 hours.

The recommended and maximum dose of tiocolchicoside is 4 mg every 6 hours (i.e., 16 mg per day). The duration of treatment is limited to 7 consecutive days.

Do not exceed the recommended dose or treatment duration.

This medicine should not be used as prolonged treatment (see section 2 "Warnings and precautions").

If the pain persists for more than 3 days, or worsens, or other symptoms appear, consult a doctor.

Use in children and adolescents

This medicine should not be administered to children and adolescents under 16 years of age for safety reasons.

Patient with liver or kidney disease: before taking the medicine, consult your doctor.

Elderly patients: consult your doctor.

If you take more Adalgur than you should

If you accidentally take more Adalgur than you should, consult your doctor or pharmacist immediately or go to the nearest hospital, taking the remaining tablets with you to inform the doctor. You can also call the Toxicology Information Service. Phone: 91 562 04 20.

If you have taken an overdose, you should go to a medical center immediately, even if you do not have symptoms, as they often do not appear until three days after taking the overdose, even in cases of severe poisoning. The symptoms of an overdose may be: dizziness, vomiting, loss of appetite, yellowing of the skin and eyes (jaundice), and abdominal pain.

Treatment of the overdose is most effective if started within 4 hours of ingestion of the medicine.

Patient taking barbiturates or chronic alcoholics may be more susceptible to the toxicity of a paracetamol overdose.

If you forget to take Adalgur

Do not take a double dose to make up for forgotten doses. If you forget to take a dose of Adalgur when it was due, take it as soon as you remember and then wait the indicated time between intakes (at least 4 to 6 hours, depending on the dose) to take the next one.

If you have any other questions about the use of this medicine, ask your doctor, pharmacist, or nurse.

Medicine questions

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4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Rare side effects (may affect up to 1 in 1,000 people)

  • Discomfort
  • Agitation, fainting
  • Allergic reactions on the skin
  • Increased levels of liver transaminases (liver enzymes),
  • Stomach pain or burning, diarrhea, nausea, vomiting
  • Hypotension (low blood pressure).

Very rare side effects (may affect up to 1 in 10,000 people)

  • Allergic reactions (hypersensitivity) ranging from a simple skin rash (redness or inflammation of the skin) or hives and anaphylactic shock (a type of severe allergic reaction). In this case, treatment should be discontinued immediately and a doctor consulted.
  • Drowsiness
  • Hepatotoxicity (liver toxicity) and jaundice (yellowing of the skin and mucous membranes).
  • Hypoglycemia (low blood sugar levels).
  • Thrombocytopenia (reduced platelet count in the blood), agranulocytosis, leukopenia, neutropenia (alterations of white blood cells in the blood), hemolytic anemia (reduced red blood cell count in the blood).
  • Pyuria (cloudy urine), kidney side effects.
  • Very rare cases of severe skin reactions have been reported.

Frequency not known (cannot be estimated from the available data): A serious disease called metabolic acidosis (an anomaly in the blood and fluids) in patients with severe disease using paracetamol (see section 2).

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist, even if it is possible side effects not listed in this leaflet. You can also report side effects directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Adalgur

Keep this medicine out of the sight and reach of children.

No special storage conditions are required.

Do not use this medicine after the expiry date stated on the packaging after EXP. The expiry date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Place the packaging and any unused medicine in the SIGRE collection point at your pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicine. This will help protect the environment.

6. Contents of the pack and other information

Composition of Adalgur tablets

  • The active ingredients are paracetamol and tiocolchicoside. Each tablet contains 500 mg of paracetamol and 2 mg of tiocolchicoside.
  • The other ingredients are: cornstarch, sodium potato carboxymethylcellulose, magnesium stearate (E572), hydroxypropylcellulose (E463), talc (E553b).

Appearance of the product and pack contents

Adalgur are round, flat, yellowish-colored tablets, scored on one side. The score line is only to facilitate breaking the tablet if you have difficulty swallowing it whole, but not to divide it into equal doses.

They are available in packs of 30 tablets.

Marketing authorization holder and manufacturer

Teofarma S.r.l.

Via F.lli Cervi, 8

27010 Valle Salimbene (PV) - Italy

Date of last revision of this leaflet:August 2025

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/.

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PATIENT CARD FOR TREATMENT WITH ADALGUR (PARACETAMOL AND TIOCOLCHICOSIDE)

Adalgur can cause harm to the fetus. Your doctor will inform you about all measures related to effective contraceptive methods and the potential risk of pregnancy.

Do not take this medicine if:

  • You are pregnant or think you may be pregnant.
  • You are breastfeeding.
  • You are a woman of childbearing age who is not using effective contraceptive methods (during treatment and for one month after stopping treatment).
  • You are a man who does not use effective contraceptive methods (during treatment and for three months after stopping treatment).

If you are pregnant, become pregnant during treatment with Adalgur, or suspect you may be pregnant, contact your doctor immediately.

For more information, read the leaflet included in the packaging, also available at https://cima.aemps.es/.

Information on risk prevention agreed with the Spanish Agency for Medicines and Health Products (AEMPS). April 2025.

Available on the AEMPS website www.aemps.gob.es.

Online doctors for ADALGUR 500 mg/2 mg TABLETS

Discuss questions about ADALGUR 500 mg/2 mg TABLETS, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Yevgen Yakovenko

General surgery 12 years exp.

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
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  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Joao Silva

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Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Hocine Lokchiri

General medicine 21 years exp.

Dr. Hocine Lokchiri is a French consultant with over 20 years of experience in General and Emergency Medicine. He works with adults and children, helping patients with urgent symptoms, infections, sudden health changes and everyday medical concerns that require timely evaluation. His background includes clinical practice in France, Switzerland and the United Arab Emirates, which allows him to navigate different healthcare systems and manage a wide range of conditions with confidence. Patients value his calm, structured approach, clear explanations and evidence-based decision-making.

Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
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  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance. His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation. Patients commonly consult Dr Daniel Cichi for: 

  • acute symptoms: fever, infections, flu-like illness, cough, sore throat, shortness of breath;
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  • muscle, joint, and back pain, minor injuries, post-traumatic symptoms;
  • chronic conditions: hypertension, diabetes, high cholesterol, thyroid disorders, weight loss, hair loss;
  • review and interpretation of lab tests, imaging reports, and medical documents;
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  • medical advice while travelling or living abroad;
  • second opinions and guidance on whether in-person care is needed.

Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.

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Doctor

Anna Biriukova

General medicine 6 years exp.

Dr Anna Biriukova is an internal medicine doctor with clinical experience in cardiology, endocrinology, and gastroenterology. She provides online consultations for adults, offering expert medical support for heart health, hormonal balance, digestive issues, and general internal medicine.

Cardiology – Diagnosis and treatment of:

  • High blood pressure, blood pressure fluctuations, and cardiovascular risk prevention.
  • Chest pain, shortness of breath, arrhythmias (tachycardia, bradycardia, palpitations).
  • Leg swelling, chronic fatigue, reduced exercise tolerance.
  • EKG interpretation, lipid profile evaluation, cardiovascular risk assessment (heart attack, stroke).
  • Post-COVID-19 cardiac monitoring and care.
Endocrinology – Diabetes, thyroid, metabolism:
  • Diagnosis and management of type 1 and type 2 diabetes, and prediabetes.
  • Individual treatment plans including oral medications and insulin therapy.
  • GLP-1 therapy– modern pharmacological treatment for weight management and diabetes control, including drug selection, monitoring, and safety follow-up.
  • Thyroid disorders – hypothyroidism, hyperthyroidism, autoimmune thyroid diseases (Hashimoto’s, Graves’ disease).
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Gastroenterology – Digestive health:
  • Abdominal pain, nausea, heartburn, gastroesophageal reflux (GERD).
  • Stomach and intestinal conditions: gastritis, irritable bowel syndrome (IBS), indigestion.
  • Management of chronic digestive disorders and interpretation of tests (endoscopy, ultrasound, labs).
General internal medicine and preventive care:
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  • Lab test analysis, therapy adjustments, medication management.
  • Adult vaccinations – planning, contraindications assessment.
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Dr Biriukova combines internal medicine with specialist insight, offering clear explanations, personalised treatment plans, and comprehensive care tailored to each patient.
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Doctor

Sviatoslav Chekhun

Oncology 13 years exp.

Dr. Sviatoslav Chekhun is a medical oncologist with international clinical and research experience, specializing in modern medical oncology and a personalized approach to cancer treatment.

Currently (since 2025), he works as a Medical Oncologist at Institut Català d’Oncologia (Girona, Spain). Previously, he completed his residency in Medical Oncology and was involved in clinical research at Hospital Universitari Germans Trias i Pujol.

Dr. Chekhun has a strong academic and scientific background. He served as a lecturer in Internal Medicine at O.O. Bohomolets National Medical University and conducted research in experimental oncology at the R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology.

Earlier in his career, he worked as a medical oncologist at the Kyiv City Clinical Oncological Center and contributed to regulatory evaluation of medicinal products at the State Expert Center of the Ministry of Health of Ukraine.

When to consult Dr. Chekhun:

  •  for diagnosis or clarification of a cancer diagnosis
  •  to obtain a second opinion on an existing treatment plan 
  •  when you need a personalized treatment strategy 
  •  for interpretation of test results, CT, MRI, PET-CT, and biopsies 
  •  when choosing between treatment options (chemotherapy, targeted therapy, immunotherapy) 
  •  in case of doubts about treatment strategy or disease progression 

Consultation format

Dr. Chekhun provides online consultations, where you can receive:

  •  expert second opinion 
  •  detailed case review 
  •  recommendations based on current international treatment guidelines 
  •  personalized treatment and follow-up plan 

Important:
Prescription and monitoring of medications must be carried out by your treating physician in an in-person (offline) setting. An online consultation does not replace a face-to-face visit but helps you make more informed decisions about your treatment.

Dr. Sviatoslav Chekhun combines clinical practice, research, and international experience, enabling him to provide patients with modern, evidence-based approaches in oncology.

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Frequently Asked Questions

Is a prescription required for ADALGUR 500 mg/2 mg TABLETS?
ADALGUR 500 mg/2 mg TABLETS requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ADALGUR 500 mg/2 mg TABLETS?
The active ingredient in ADALGUR 500 mg/2 mg TABLETS is thiocolchicoside, combinations. This information helps identify medicines with the same composition but different brand names.
Who manufactures ADALGUR 500 mg/2 mg TABLETS?
ADALGUR 500 mg/2 mg TABLETS is manufactured by Teofarma S.R.L.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ADALGUR 500 mg/2 mg TABLETS online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ADALGUR 500 mg/2 mg TABLETS is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ADALGUR 500 mg/2 mg TABLETS?
Other medicines with the same active substance (thiocolchicoside, combinations) include BACLOFEN COMBIX 10 mg TABLETS, LIORESAL 0.05 mg/mL Injectable Solution, LIORESAL 0.5 mg/mL SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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