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ACTIMAG 400 MG/ML ORAL SOLUTION

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About the medicine

How to use ACTIMAG 400 MG/ML ORAL SOLUTION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Package Leaflet: Information for the User

ACTIMAG 400 mg/mL Oral Solution

Magnesium pidolate

Read this package leaflet carefully before starting to take this medicine, as it contains important information for you.

Follow the administration instructions for the medicine contained in this package leaflet or as indicated by your doctor or pharmacist.

  • Keep this package leaflet, as you may need to read it again.
  • If you need advice or more information, consult your pharmacist.
  • If you experience side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. See section 4.
  • You should consult a doctor if your condition worsens or does not improve after 7 days.

Contents of the Package Leaflet

  1. What is Actimag and what is it used for
  2. What you need to know before taking Actimag
  3. How to take Actimag
  4. Possible side effects
  5. Storage of Actimag
  6. Package Contents and Additional Information

1. What is Actimag and what is it used for

Actimag 400 mg/mL Oral Solution belongs to the group of medicines called magnesium supplements. It is indicated for adults and children over 12 years of age for the prevention and treatment of low magnesium levels in the body.

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2. What you need to know before taking Actimag

Do not take Actimag

  • If you are allergic to magnesium pidolate, magnesium, or any of the other components of this medicine (listed in section 6).
  • If you have abnormally high magnesium levels in your blood.
  • If you have had severe kidney problems.
  • If you have chronic diarrhea.
  • If you have any intestinal problems, consult your doctor before using this medicine.
  • If you have muscle weakness and/or fatigue (myasthenia gravis)
  • If you have had any part of your intestine removed
  • If you have Cushing's disease (excess cortisol)
  • If you have had diabetic coma (loss of consciousness due to excessively high or low blood glucose levels)
  • If you have had heart diseases such as angina pectoris or myocardial infarction.
  • If you have any alterations in calcium metabolism

Warnings and Precautions

Consult your doctor or pharmacist before starting to take Actimag.

  • Do not use this medicine continuously without medical supervision. Continuous use of this medicine can cause hypermagnesemia (high magnesium levels in the blood) characterized by nausea, vomiting, respiratory depression (weak breathing), and central nervous system depression (symptoms can range from numbness to coma), hyperreflexia (exaggerated reflexes), muscle weakness, and certain cardiovascular effects such as low blood pressure, decreased heart rate, and cardiac arrest.
  • Continuous use of this medicine can cause hypercalcemia (high calcium levels in the blood)
  • Use this medicine with caution in case of prolonged treatment, as it may be necessary to regularly monitor magnesium and calcium levels in the blood.
  • Taking this medicine on an empty stomach can cause diarrhea.
  • Patient with kidney diseases should consult their doctor before starting to take this medicine.

Children and Adolescents

Do not administer to children under 12 years of age unless medically prescribed.

Other Medicines and Actimag

Tell your doctor or pharmacist if you are using, have recently used, or may need to use any other medicine, including those obtained without a prescription.

Note that these instructions may also apply to medicines used before or after.

Magnesium can bind to certain medicines and prevent their complete absorption.

This medicine reduces the absorption of:

  • Antibiotics, such as tetracyclines (doxycycline, minocycline, oxytetracycline, tetracycline) and quinolones (ciprofloxacin, levofloxacin, norfloxacin, ofloxacin).
  • Bisphosphonates (medicines used in the treatment of osteoporosis, such as alendronate).
  • Antifungals (for treating fungal infections) of the azole type (e.g., ketoconazole)

The administration of Actimag and these medicines should be spaced at least 2 hours apart to avoid unwanted interactions.

If you are taking any of the following medicines:

  • Sodium polystyrene sulfonate (medicine for treating hyperkalemia)
  • Calcium supplements

Ask your doctor or pharmacist how much to space the doses and establish a dosing schedule that makes it easier to take these medicines.

  • Taking delavirdine (medicine used as part of antiretroviral therapy for the treatment of HIV-1) simultaneously with Actimag may reduce the effect of this medicine, so the administration of delavirdine with Actimag should be spaced at least 1 hour apart.

Review the information of any medicine or herbal remedy you are taking (such as antacids, laxatives, vitamins) as they may contain magnesium. Additionally, there are other possible interactions of Actimag with other medicines used to treat heart diseases, as well as with alcohol and glucose. Ask your doctor or pharmacist how to safely use these products.

Using Actimag with Food and Drinks

Excessive and prolonged consumption of products containing magnesium and calcium can cause excessive calcium concentrations in the blood. In these situations, calcium intake and foods rich in calcium, such as dairy products, should be monitored.

Taking this medicine with food intake

Pregnancy and Breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor or pharmacist before using this medicine.

Pregnancy

This medicine can be used during pregnancy only in cases where it is strictly necessary.

It is recommended to cover magnesium needs with a diet rich in vegetables, whole grains, and legumes to prevent the consequences of magnesium deficiency during pregnancy.

Breastfeeding

Consult your doctor if you are breastfeeding your baby.

No problems have been reported in breastfed children whose mothers take magnesium at the recommended doses.

Driving and Using Machines

The influence of Actimag on the ability to drive or use machines is negligible.

Actimagcontains sucrose, methyl parahydroxybenzoate (E-218), propyl parahydroxybenzoate (E-216), amaranth (E-123), propylene glycol (E-1520), and sodium.

This medicine contains sucrose. If your doctor has told you that you have an intolerance to certain sugars, consult with them before taking this medicine.

It may cause allergic reactions (possibly delayed) because it contains methyl parahydroxybenzoate (E-218) and propyl parahydroxybenzoate (E-216).

This medicine may cause allergic reactions because it contains amaranth (E-123). It can cause asthma, especially in patients allergic to acetylsalicylic acid.

This medicine contains 8.66 mg of propylene glycol in each dose unit (10 mL).

This medicine contains less than 23 mg of sodium (1 mmol) per dose unit (5 mL); it is essentially "sodium-free".

3. How to Take Actimag

Follow the administration instructions for the medicine contained in this package leaflet or as indicated by your doctor or pharmacist. If in doubt, ask your doctor or pharmacist.

This medicine is administered orally.

The recommended dose in adults and children over 12 years of age is 5 mL twice a day.

Do not exceed the recommended daily doses.

Method of Administration

It is recommended to take this medicine with food intake, unless your doctor indicates otherwise, in order to reduce gastric discomfort and diarrhea.

Use in Children

This medicine should not be used in children unless medically prescribed.

Use in Elderly

In elderly patients (65 years) with reduced kidney function, the dose and frequency of administration of magnesium salts should be adjusted by the doctor according to the degree of renal function impairment.

If You Take More Actimag Than You Should

If you take an excessive dose of this medicine, the following symptoms may appear: nausea, vomiting, decreased blood pressure, and in severe cases, skin vasodilation, slowed heart rate, and central nervous system depression.

If you observe any of these symptoms, consult your doctor or pharmacist immediately or go to the emergency department of the nearest hospital. Bring this package leaflet with you. You can also call the Toxicology Information Service at 91.562.04.20, indicating the medicine and the amount taken.

If You Forget to Take Actimag

Remember to take your medicine. If you forget to take a dose, take it as soon as possible, unless it is almost time for the next dose. Do not take a double dose to make up for forgotten doses.

If You Stop Taking Actimag

If you have any further questions about the use of this medicine, ask your doctor or pharmacist.

Medicine questions

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4. Possible Side Effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

The following side effects have been observed, although their frequency cannot be established with precision:

Gastrointestinal disorders:

  • Occasionally: gastric discomfort, diarrhea
  • Vascular disorders
  • Hypotension

In rare cases, a severe allergic reaction may occur. Consult your doctor immediately if you show any of the following symptoms: flushing, itching/swelling (especially of the face, tongue, or throat), dizziness, and/or breathing difficulties.

Reporting Side Effects

If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this package leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines: https://www.notificaRAM.es/. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Actimag

Keep this medicine out of the sight and reach of children.

No special storage conditions are required.

Do not use this medicine after the expiration date stated on the packaging, after EXP. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and any unused medicines in the pharmacy's SIGRE collection point. If in doubt, ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Package Contents and Additional Information

Composition of Actimag 400 mg/mL Oral Solution

  • The active ingredient is magnesium pidolate. Each mL of oral solution contains 400 mg of magnesium pidolate (equivalent to 34.7 mg of magnesium).
  • The other ingredients are: sucrose, propylene glycol, sodium saccharin, methyl parahydroxybenzoate (E-218), propyl parahydroxybenzoate (E-216), raspberry flavor, peppermint flavor, amaranth (E-123) coloring, and water.

Appearance of the Product and Package Contents

Glass bottle with a polypropylene/polyethylene high-density (PP/HDPE) cap with a child-resistant closure, containing 100 mL of oral solution and a measuring dosing device.

Marketing Authorization Holder

Faes Farma, S.A.

Autonomia Etorbidea, 10

48940 Leioa (Bizkaia)

Spain

Manufacturer

Faes Farma, S.A.

Parque Científico y Tecnológico de Bizkaia

Ibaizabal Bidea, Edificio 901

48160 Derio (Bizkaia)

Spain

Date of the Last Revision of this Package Leaflet:November 2021

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Online doctors for ACTIMAG 400 MG/ML ORAL SOLUTION

Discuss questions about ACTIMAG 400 MG/ML ORAL SOLUTION, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

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Tarek Agami

General medicine 11 years exp.

Dr. Tarek Agami is a general practitioner registered in both Portugal and Israel, with broad experience in family and preventive medicine. He offers online consultations for adults and children, providing personalised support for primary care needs, chronic disease management, and everyday health concerns.

Dr. Agami received clinical training and worked in leading medical institutions in Israel (Kaplan Medical Center, Barzilai Medical Center, Wolfson Medical Center) and Portugal (European Healthcare City, Viscura Internacional, Hospital Dr. José Maria Grande, Hospital Vila Franca de Xira). His approach combines international medical standards with individualised attention to each patient.

Main areas of consultation:

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  • Medical support during travel or after relocation
  • Treatment adjustments and lifestyle recommendations based on your personal history
Dr. Agami provides medical support for patients using GLP-1 medications (such as Ozempic or Mounjaro) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Portugal and Israel.

Dr. Agami is committed to evidence-based, patient-centred care, ensuring that each person receives trusted medical support tailored to their health goals.

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Nuno Tavares Lopes

Family medicine 18 years exp.

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies
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Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.

Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

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Anastasiia Shalko

Family medicine 13 years exp.

Dr. Anastasiia Shalko is a general practitioner with a background in both paediatrics and general medicine. She graduated from Bogomolets National Medical University in Kyiv and completed her paediatric internship at the P.L. Shupyk National Medical Academy of Postgraduate Education. After working as a paediatrician in Kyiv, she relocated to Spain, where she has been practising general medicine since 2015, providing care for both adults and children.

Her work focuses on urgent, short-term medical concerns – situations where patients need quick guidance, symptom assessment and clear next steps. She helps people understand whether their symptoms require in-person evaluation, home management or a change in treatment. Common reasons for booking an online consultation include:

  • acute respiratory symptoms (cough, sore throat, runny nose, fever)
  • viral illnesses such as colds and seasonal infections
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Dr. Shalko works specifically with urgent and short-term problems, providing practical recommendations and helping patients determine the safest next step. She explains symptoms clearly, guides patients through decision-making and offers straightforward medical advice for everyday acute issues.

She does not provide long-term management of chronic conditions, ongoing follow-up or comprehensive care plans for complex long-term illnesses. Her consultations are designed for acute symptoms, sudden concerns and situations where timely medical input is important.

With clinical experience in both paediatrics and general medicine, Dr. Shalko confidently supports adults and children. Her communication style is clear, simple and reassuring, helping patients feel informed and supported throughout the consultation.

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Tomasz Grzelewski

Dermatology 21 years exp.

Dr Tomasz Grzelewski is an MD, PhD specialist in allergy, paediatrics, general practice and sports medicine, with a clinical focus on dermatology, endocrinology, allergology and sports-related health. He has more than 20 years of clinical experience and completed his medical training at the Medical University of Łódź, where he defended his PhD thesis with distinction. His doctoral research was recognised by the Polish Society of Allergology for its innovative contribution to the field. Throughout his career, he has gained extensive expertise in diagnosing and managing a wide range of allergic and paediatric conditions, including modern allergen desensitisation techniques.

For five years, Dr Grzelewski served as the Head of two paediatric departments in Poland, managing complex clinical cases and leading multidisciplinary teams. He also worked in medical centres in the United Kingdom, gaining experience across both primary care and specialist environments. With over a decade of telemedicine experience, he has provided online consultations across Europe and is valued for his clear, structured and evidence-based medical guidance.

Dr Grzelewski is actively involved in clinical programmes focused on modern anti-allergic therapies. As a Principal Investigator, he leads research projects on sublingual and oral allergen desensitisation, supporting evidence-based progress in allergy treatment for both children and adults.

In addition to his background in allergology and paediatrics, he completed dermatology studies through the Cambridge Education Group (Royal College of Physicians of Ireland) and a Clinical Endocrinology course at Harvard Medical School. This advanced training enhances his ability to manage skin manifestations of allergies, atopic conditions, urticaria, endocrine-related symptoms and complex immunological reactions.

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Dr Tomasz Grzelewski is known for his clear communication style, structured medical approach and ability to explain treatment options in a concise and accessible way. His multidisciplinary background across allergy, paediatrics, dermatology and endocrinology allows him to provide safe, up-to-date and comprehensive care for patients of all ages.
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Daniel Cichi

Family medicine 24 years exp.

Dr Daniel Cichi is a family medicine doctor with over 20 years of clinical experience. He provides online consultations for adults, supporting patients with acute symptoms, chronic conditions, and everyday health concerns that require timely medical guidance.

His background includes work in emergency care, ambulance services, and family medicine, which allows him to assess symptoms quickly, identify warning signs, and help patients choose the safest next steps – whether that means home care, treatment adjustment, or in-person evaluation.

Patients commonly consult Dr Daniel Cichi for:

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Dr Cichi’s consultations are structured and practical. He focuses on clear explanations, risk assessment, and actionable recommendations, helping patients understand their symptoms and make informed decisions about their health.
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Frequently Asked Questions

Is a prescription required for ACTIMAG 400 MG/ML ORAL SOLUTION?
ACTIMAG 400 MG/ML ORAL SOLUTION does not require a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ACTIMAG 400 MG/ML ORAL SOLUTION?
The active ingredient in ACTIMAG 400 MG/ML ORAL SOLUTION is magnesium pidolate. This information helps identify medicines with the same composition but different brand names.
Who manufactures ACTIMAG 400 MG/ML ORAL SOLUTION?
ACTIMAG 400 MG/ML ORAL SOLUTION is manufactured by Faes Farma S.A.. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ACTIMAG 400 MG/ML ORAL SOLUTION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ACTIMAG 400 MG/ML ORAL SOLUTION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ACTIMAG 400 MG/ML ORAL SOLUTION?
Other medicines with the same active substance (magnesium pidolate) include MAGNESIUM NM 200 MG ORAL SOLUTION POWDER IN SACHET, MAGNESIOBOI 48.62 mg TABLETS, MAGNOGENE 53 mg FILM-COATED TABLETS. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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