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ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION

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About the medicine

How to use ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION

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This page provides general information and does not replace a doctor’s consultation. Always consult a doctor before taking any medication. Seek urgent medical care if symptoms are severe.

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Introduction

Leaflet: information for the user

Accusol 35, solution for hemofiltration, hemodialysis, and hemodiafiltration

Read this leaflet carefully before this medicine is administered to you, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, ask your doctor.
  • If you experience side effects, ask your doctor, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What Accusol 35 is and what it is used for
  2. What you need to know before Accusol 35 is administered to you
  3. How Accusol 35 will be administered to you
  4. Possible side effects
  5. Storage of Accusol 35
  6. Package contents and additional information

1. What Accusol 35 is and what it is used for

Accusol 35 is a solution for hemofiltration, hemodialysis, and hemodiafiltration.

Accusol 35 is indicated in patients with acute or chronic renal failure.

It cleans the blood of waste products; corrects acidosis or alkalinity and abnormal levels of salts in the blood. As a replacement solution in hemodiafiltration and hemofiltration, it can also be used as a source of salts and water for hydration.

The Accusol 35 solutions are presented in a two-compartment bag (bicompartimental) that does not contain PVC. A long seal (seal between the chambers) separates the two chambers. Before use, the solutions from the two Accusol 35 chambers must be mixed by opening the long seal (seal between the chambers), followed by opening the short SafetyMoon seal located near the access port.

Accusol 35 is especially indicated if you have a high level of potassium.

The Accusol 35 solutions should only be used under the supervision of a doctor.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before Accusol 35 is administered to you

Your doctor will ensure that you have adequate blood access to perform the procedure and that there is no risk of bleeding.

The Accusol 35 solutions are available in different concentrations of potassium and glucose. The levels of potassium and glucose in your blood will be carefully checked to ensure that the most suitable Accusol 35 formulation is used.

Your doctor will not administer Accusol 35 to you

  • if you do not have good access to your veins and/or arteries
  • if you have a high risk of bleeding
  • if you have a high level of bicarbonate in your blood
  • if you have a very low level of potassium in your blood, unless you are receiving a potassium supplement at the same time
  • if you have a clinical condition in which the levels of acidity or alkalinity in your blood may worsen
  • if you have a renal disorder in which waste products cannot be removed from the blood by hemofiltration

Warnings and precautions

Accusol 35 should only be used by or under the supervision of a doctor with experience in hemofiltration, hemodialysis, or hemodiafiltration techniques.

Your doctor

  • will measure the acidity, salt levels, and waste products in your blood
  • will ensure that the levels are correct and will closely monitor them during treatment
  • will ensure that a good fluid balance is maintained
  • will closely monitor your blood glucose levels, especially if you are diabetic
  • will regularly measure the level of potassium in your blood
  • will ensure, before use, that the contents of both chambers are mixed by opening the long seal (seal between the chambers), followed by opening the short SafetyMoon seal located near the access port. If the doctor perfuses with an unmixed solution, your bicarbonate level in the blood may increase. This can cause side effects such as nausea, drowsiness, headache, heart rhythm disturbances, and difficulty breathing.

Other medicines and Accusol 35

Tell your doctor if you are taking, have recently taken, or may take any other medicine.

The administration of Accusol 35 may affect the action of other medicines.

  • If you are taking vitamin D or other medicines that contain calcium, your calcium level in the blood may be altered.
  • If you are taking additional sodium bicarbonate, there is a greater risk of abnormal salt and alkalinity levels (alkalosis) in your blood.
  • If you are taking heart medicines called cardiac glycosides, you may need potassium supplements. Your doctor will closely monitor you during treatment.

Pregnancy and breastfeeding

Tell your doctor if you are pregnant or breastfeeding. The doctor will evaluate the benefits of using Accusol 35 against the risks.

3. How Accusol 35 will be administered to you

Depending on your treatment, your doctor will administer Accusol 35 through the tube of the dialysis machine.

The hemofiltration, hemodialysis, or hemodiafiltration treatment you receive will depend on your clinical condition, physical examination, laboratory test results, and response to treatment.

Your doctor will determine the suitable formula and amount of Accusol 35 solutions for your clinical condition.

Dose and frequency

Your doctor will decide and adjust the volume and rate of administration of the solution to be administered.

The amount of fluid needed will depend on the use of Accusol.

If you are an adult or elderly patient and

  • are being treated with Accusol 35 as a replacement solution due to chronic renal failure, you should be administered 7 to 35 ml/kg/h or more
  • are being treated with Accusol 35 as a replacement solution due to acute renal failure, you should be administered 20 to 35 ml/kg/h or more
  • are being treated with Accusol 35 as a dialysis solution due to chronic or acute renal failure, the amount of solution should be determined according to the frequency and duration of treatment.
Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The rare possible side effects of Accusol 35 Potassium 4 mmol/l (which occur in less than 1 in 1000 patients)include:

??Low blood glucose level (hypoglycemia).

You may experience other side effects. It is possible that these side effects are not all due to the solutions or treatment. The possible side effects that may occur are:

??Decrease (hypovolemia) or increase (hypervolemia) in body fluid volume

??Decrease (hypotension) or increase (hypertension) in blood pressure

??Very low levels of phosphate in the blood (hypophosphatemia)

??Alterations in the level of alkalinity in the blood (alkalosis)

??Dizziness

??Vomiting

??Muscle cramps

??Bleeding disorder

??Infection

??Difficulty breathing, irregular breathing (caused by air bubbles in the bloodstream)

??Alteration of the levels of different salts in the blood (e.g., alteration of sodium, potassium, calcium in the blood)

??Increased blood coagulation

Reporting of side effects

If you experience side effects, ask your doctor, even if they are not listed in this leaflet. You can also report them directly through the Spanish Pharmacovigilance System for Human Use Medicines:

www.notificaRAM.es

5. Storage of Accusol 35

Keep this medicine out of the sight and reach of children.

Do not refrigerate or freeze.

Do not use this medicine after the expiration date stated on the label and on the packaging after CAD. The expiration date is the last day of the month indicated.

Your doctor will not use Accusol 35 if the solution is not transparent or the packaging is damaged.

Medicines should not be disposed of via wastewater or household waste. Deposit the packaging and medicines you no longer need in the SIGRE collection point at the pharmacy. If in doubt, ask your pharmacist how to dispose of the packaging and medicines you no longer need. This will help protect the environment.

6. Package contents and additional information

Medicine name

Accusol 35, solution for hemofiltration, hemodialysis, and hemodiafiltration.

Composition of the Accusol 35 solution:

Composition

Per 1000 ml Accusol 35

Large chamber'A'

Calcium chloride dihydrate

0.343 g

Magnesium chloride hexahydrate

0.136 g

Sodium chloride

7.52 g

Large chamber'B'

Sodium bicarbonate

13.4 g

The 5000 ml of final solution result from the mixture of 3750 ml of solution 'A' with 1250 ml of solution 'B'.

Ionic composition of the final solution:

Per 1000 ml Accusol 35

Calcium (Ca++)

1.75 mmol

Magnesium (Mg++)

0.5 mmol

Sodium (Na+)

140 mmol

Chloride (Cl-)

109.3 mmol

Bicarbonate (HCO3-)

35 mmol

Theoretical osmolality

287 mOsm/l

The other components are: water for injectable preparations, hydrochloric acid, sodium hydroxide, and disodium phosphate dihydrate.

Appearance of Accusol 35 and package contents

Accusol 35 is supplied in a cardboard box containing two 5-liter two-chamber bags that do not contain PVC.

Each bag is wrapped in an overbag.

The solution in the bag is transparent and colorless.

Marketing authorization holder:

Nikkiso Belgium

Industriepark 6

3300 Tienen

Belgium

Local representative:

Palex Medical S.A.

Jesus Serra Santamans, 5

08174 Sant Cugat del Valles

Spain

Manufacturer:

Baxter Healthcare S.A.

Moneen Road

Castlebar

County Mayo – Ireland

or

Serumwerk Bernburg AG

Hallesche Landstrasse 105b

06406 Bernburg

Germany

Date of last revision of this leaflet: 07/2018

Detailed and updated information on this medicine is available on the website of the Spanish Agency for Medicines and Health Products (AEMPS) http://www.aemps.gob.es/

Accusol is a registered trademark of Nikkiso International Inc.

Online doctors for ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION

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Online consultations with Dr. Lokchiri are suitable for many situations when someone needs quick medical guidance, reassurance or a clear next step. Common reasons for booking include:

  • fever, chills, fatigue and viral symptoms
  • cough, sore throat, nasal congestion, breathing discomfort
  • bronchitis and mild asthma flare-ups
  • nausea, diarrhoea, abdominal pain, digestive infections
  • rashes, allergic reactions, redness, insect bites
  • muscle or joint pain, mild injuries, sprains
  • headache, dizziness, migraine symptoms
  • stress-related symptoms, sleep disturbances
  • questions about test results and treatment plans
  • management of chronic conditions in stable phases
Many patients reach out when symptoms appear suddenly and cause concern, when a child becomes unwell unexpectedly, when a rash changes or spreads, or when it’s unclear whether an in-person examination is necessary. His emergency medicine background is particularly valuable online, helping patients understand risk levels, identify warning signs and choose safe next steps.

Some situations are not suitable for online care. If a patient has loss of consciousness, severe chest pain, uncontrolled bleeding, seizures, major trauma or symptoms suggesting a stroke or heart attack, he will advise seeking immediate local emergency services. This improves safety and ensures patients receive the right level of care.

Dr. Lokchiri’s professional training includes:

  • Advanced Trauma Life Support (ATLS)
  • Basic and Advanced Cardiac Life Support (BLS/ACLS)
  • Pediatric Advanced Life Support (PALS)
  • Prehospital Trauma Life Support (PHTLS)
  • eFAST and critical care transthoracic echocardiography
  • aviation medicine
He is an active member of several professional organisations, including the French Society of Emergency Medicine (SFMU), the French Association for Emergency Physicians (AMUF) and the Swiss Society of Emergency and Rescue Medicine (SGNOR). In consultations, he works with clarity and precision, helping patients understand their symptoms, possible risks and the safest treatment options.
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Chikeluo Okeke

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Dr Chikeluo Okeke is an internal medicine doctor with extensive international clinical experience. Originally from Nigeria, he has worked across multiple European healthcare systems and currently practises in Sweden. This professional path has given him a strong understanding of different medical approaches and the ability to work effectively with patients from diverse cultural and linguistic backgrounds.

Dr Okeke focuses on general internal medicine and adult primary care, combining clinical accuracy with careful attention to lifestyle, personal context, and everyday health concerns. His consultations are particularly well suited for people who seek medical advice online, live abroad, or need clear guidance without unnecessary complexity.

He provides online consultations covering symptom assessment, prevention, and long-term management of chronic conditions, helping patients understand what is happening and decide on appropriate next steps.

Common reasons for consultation:

  • General internal medicine concerns and initial health assessment.
  • Acute symptoms such as fever, cough, infections, pain, or weakness.
  • Chronic conditions and treatment adjustment.
  • Blood pressure issues, fatigue, metabolic concerns.
  • Preventive consultations and routine check-ups.
  • Interpretation of laboratory results and medical reports.
  • Medical advice for patients receiving care online.

Dr Okeke is known for his clear communication, calm approach, and cultural awareness. He listens carefully, explains medical decisions in a structured way, and supports patients in making informed choices about their health.

Online consultations with Dr Chikeluo Okeke offer reliable internal medicine care without geographic limitations, focused on medical relevance, clarity, and patient comfort.

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Dr. Tsurkan supports patients with a wide range of health issues, including:

  • Respiratory infections: cold, flu, bronchitis, pneumonia, and lingering coughs.
  • ENT conditions: sinusitis, tonsillitis, otitis (ear infections), sore throat, allergic rhinitis.
  • Eye conditions: allergic or infectious conjunctivitis, red eyes, irritation.
  • Digestive issues: acid reflux (GERD), gastritis, irritable bowel syndrome (IBS), constipation, bloating, nausea.
  • Urinary and reproductive health: urinary tract infections (UTIs), cystitis, prevention of recurrent infections.
  • Chronic diseases: hypertension, elevated cholesterol, weight management.
  • Neurological complaints: headaches, migraines, sleep disturbances, fatigue, general weakness.
  • Children’s health: fever, infections, digestive issues, follow-ups, vaccination guidance.

She also provides:

  • IMT medical certificates for driving licence exchange in Portugal.
  • Personalised preventive care and wellness consultations.
  • Interpretation of test results and medical reports.
  • Follow-up care and medication review.
  • Support in managing multiple coexisting conditions.
  • Remote prescription management and medical documentation.

Dr. Tsurkan’s approach is evidence-based and holistic. She works closely with each patient to develop an individualised care plan that addresses both symptoms and root causes. Her goal is to empower patients to take control of their health and maintain well-being through lifestyle adjustments, routine check-ups, and early intervention.

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His approach is clear: to listen, organize your case, and provide you with a practical roadmap based on evidence-based medicine and adapted to your medical history and personal needs.

Pain: how he can help

  • Chronic pain (more than 3 months
  • Migraine and recurrent or high-intensity headaches
  •  Neck, lower back, back and joint pain
  •  Post-traumatic pain after injuries or surgeries
  •  Pain of neurological origin: neuralgia, neuropathic pain, fibromyalgia

General medicine

  • Frequent respiratory infections (cold, flu, persistent cough)
  • Hypertension, diabetes and metabolic disorders
  • Review of laboratory tests and MRI/CT reports (explained in clear language)
  • Preventive medicine and health monitoring
  • Second opinions and treatment adjustments (when clinically appropriate)

What the consultation is like
 Each session lasts up to 30 minutes. We review symptoms, medical history, medications and any tests you provide, and you finish the consultation with a clear treatment plan, defined next steps, and criteria to understand when follow-up may be needed. If warning signs are detected, he will clearly advise whether you need in-person care or urgent medical attention.

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Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

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Joao Silva

General medicine 6 years exp.

Dr. João Silva is a physician with training and experience in the field of General and Family Medicine, dedicated to providing healthcare focused on the well-being and quality of life of his patients. Throughout his professional career, he has developed broad clinical competencies, striving to maintain a medical practice based on scientific evidence and continuous knowledge updates.

Between 2013 and 2019, he completed the Integrated Master's Degree in Medicine at the Abel Salazar Institute of Biomedical Sciences in Porto, where he acquired a solid academic and clinical education.

Subsequently, between January 2021 and December 2021, he completed the General Internship at the Entre Douro e Vouga Hospital Center in Santa Maria da Feira, where he had the opportunity to work in different hospital settings and deepen his competencies in several areas of medicine.

From January 2022 until March 2026, he works as a Resident Physician in General and Family Medicine at USF Salvador Machado in Oliveira de Azeméis, developing clinical activities in primary healthcare, follow-up of chronic patients, and health promotion in the community.

Complementing his medical training, Dr. João Silva also completed a Postgraduate Degree in Continuing and Palliative Care at CESPU, strengthening his preparation in the comprehensive approach to patient care, especially in situations requiring prolonged care and multidisciplinary support.

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Doctor

Lina Travkina

Family medicine 13 years exp.

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.

Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.
  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.
  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.
  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.
  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.
  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.
  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.
  • Medical advice and follow-up consultations.
  • Test interpretation and diagnostic guidance.
  • Structured support for undiagnosed complaints.
  • Second opinion on diagnoses and treatment plans.
  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.
  • Post-operative recovery support and pain management.
  • Preconception counselling and postpartum support.
  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.

If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

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Frequently Asked Questions

Is a prescription required for ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION?
ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.
What is the active substance in ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION?
The active ingredient in ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION is Hemofiltrates. This information helps identify medicines with the same composition but different brand names.
How much does ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION cost in pharmacies?
The average pharmacy price for ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION is around 39.95 EUR. Prices may vary depending on the manufacturer and dosage form.
Who manufactures ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION?
ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION is manufactured by Nikkiso Belgium. Pharmacy brands and packaging may differ depending on the distributor.
Which doctors can assess the use of ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION online?
Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.
What are the alternatives to ACCUSOL 35 SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION?
Other medicines with the same active substance (Hemofiltrates) include ACCUSOL 35 POTASSIUM 2 mmol/L SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION, ACCUSOL 35 POTASSIUM 4 mmol/L SOLUTION FOR HEMOFILTRATION, HEMODIALYSIS AND HEMODIAFILTRATION, CIFOBAN 136 mmol/L SOLUTION FOR INFUSION. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.
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