Package Leaflet: Information for the user

paliperidone cinfa 6 mg prolonged-release tablets EFG

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

• Keep this leaflet, as you may need to read it again.
• If you have any questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not give it to others even if they have similar symptoms to you, as it may harm them.
• If you experience any side effects, consult your doctor or pharmacist, even if they are not listed in this leaflet. See section 4.

Paliperidone contains the active ingredient paliperidone, which belongs to the class ofmedicamentosantipsicóticos.

Paliperidone is used to treat schizophrenia in adults and adolescents aged 15 years and older.

Schizophrenia is a disorder that causes symptoms that include hearing, seeing or feeling things thatdonotexist, holding false beliefs, having an abnormal distrust, withdrawing into oneself,speaking incoherently and flattening of behavior and emotion. People with this disorder may also feeldepressed,anxious,guiltyortense.

Paliperidone is also used to treat schizoaffective disorder in adults.

Schizoaffective disorder is a mental condition in which the person experiences several of the symptoms of schizophrenia (listed in the previous paragraph) in addition to symptoms of mood disorder (feeling of euphoria, sadness, agitation, being distracted, insomnia, loquacity,lossof interest in daily activities, excessive or inadequate sleep, excessive or inadequate food intake, and recurring thoughts ofsuicidio).

Paliperidone may help alleviate the symptoms of your illness and prevent it fromrelapseting.

Do not take paliperidone cinfa

• If you are allergic to paliperidone, risperidone, or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor or pharmacist before starting to take paliperidone cinfa.

• Patients with schizoaffective disorder treated with this medicine should be closely monitored for any change in manic symptoms to depressive symptoms.
• This medicine has not been studied in elderly patients with dementia. However, elderly patients with dementia treated with similar medicines may have an increased risk of stroke or death (see section 4, Possible side effects).
• If you have Parkinson's disease or dementia.
• If you have ever been diagnosed with a condition characterized by high temperature and muscle rigidity (also known as Neuroleptic Malignant Syndrome).
• If you have ever experienced abnormal movements of the tongue or face (Tardive Dyskinesia).

You should know that these two conditions may be caused by this type of medicine.

• If you have had low white blood cell counts in the past (which may or may not have been caused by other medicines)
• If you are diabetic or have a tendency to develop diabetes.
• If you have any heart disease or are receiving treatment for heart diseases that may make you more prone to a drop in blood pressure.
• If you have epilepsy.
• If you have any swallowing, stomach, or intestinal disorders that reduce your ability to swallow food or digest it normally.
• If you have diseases associated with diarrhea.
• If you have kidney problems.
• If you have liver problems.
• If you have an erection that lasts for a long time and/or is painful.
• If you have difficulty controlling your body temperature or are feeling overheated.
• If you have an abnormally high level of prolactin in your blood or if you have a tumor that may be dependent on prolactin.
• If you or a family member has a history of blood clots, as antipsychotics are associated with the formation of blood clots.

If you have any of these conditions, please consult your doctor as it may be necessary to adjust your dose or keep you under observation for a while.

Because in very rare cases, a dangerously low number of a type of white blood cell necessary to fight infections in the blood has been observed in patients treated with paliperidone, your doctor may check your white blood cell count.

Paliperidone may cause you to gain weight. Significant weight gain can negatively affect your health. Your doctor will regularly monitor your weight.

In patients treated with paliperidone, diabetes mellitus or worsening of pre-existing diabetes mellitus has been observed. Your doctor should check for signs of increased blood sugar. In patients with pre-existing diabetes mellitus, blood sugar should be regularly monitored.

During eye surgery for cataracts, the pupil (the black circle in the middle of the eye) may not dilate as needed. Additionally, the iris (the colored part of the eye) may become flaccid during surgery and this may cause eye damage. If you are planning to have eye surgery, make sure to inform your ophthalmologist that you are taking this medicine.

Children and adolescents

Paliperidone should not be administered to children and adolescents under 15 years old for the treatment of schizophrenia.

Paliperidone should not be administered to children and adolescents under 18 years old for the treatment of schizoaffective disorder.

This is because it is unknown whether paliperidone is safe or effective in this age group.

Other medicines and paliperidone cinfa

Inform your doctor or pharmacist if you are taking, have taken recently, or may need to take any other medicine.

Abnormalities in heart function may occur when this medicine is taken with other medicines for heart rhythm control or other medicines such as antihistamines, antimalarials, or antipsychotics.

Since this medicine primarily acts on the brain, this medicine may interfere with other medicines (or alcohol) that also act on it, due to the sum of effects on brain function.

This medicine may lower blood pressure, so you should be careful if you take this medicine with other medicines that also lower blood pressure.

This medicine may reduce the effect of medicines for Parkinson's disease and restless leg syndrome (e.g., levodopa).

The effects of this medicine may be affected if you take medicines that influence the speed of intestinal movement (e.g., metoclopramide).

Reduction of this medicine dose should be considered when this medicine is administered with valproate.

The use of risperidone oral with this medicine is not recommended as this combination may cause an increase in adverse effects.

Paliperidone should be used with caution with medicines that increase the activity of the central nervous system (psychoestimulants such as methylphenidate).

Paliperidone cinfa and alcohol

You should avoid consuming alcohol during treatment with this medicine.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, or think you may be pregnant, consult your doctor or pharmacist before using this medicine.

You should not take this medicine during pregnancy unless you have discussed it with your doctor. The following symptoms may occur in newborn babies of mothers who have been treated with paliperidone in the last three months of pregnancy (last trimester of pregnancy): tremor, rigidity, and/or muscle weakness, drowsiness, agitation, breathing problems, and difficulty feeding. If your baby develops any of these symptoms, contact your doctor.

You should not take this medicine during breastfeeding.

Driving and operating machinery

Paliperidone may cause symptoms such as drowsiness, dizziness, or visual disturbances, and may decrease your reaction time. These effects, as well as the underlying condition, may make it difficult for you to drive vehicles or operate machinery. Therefore, do not drive, operate machinery, or engage in other activities that require special attention until your doctor assesses your response to this medicine.

Paliperidone cinfa contains sodium

This medicine contains less than 1 mmol of sodium (23 mg) per tablet; it is essentially "sodium-free".

Follow exactly the administration instructions for this medication as indicated by your doctor. In case of doubt, consult your doctor or pharmacist again.

Use in adults

The recommended dose in adults is 6 mg once a day in the morning. Your doctor may increase or decrease it within the dosing interval of 3 mg to 12 mg once a day in case of schizophrenia or 6 mg to 12 mg once a day in case of schizoaffective disorder. This depends on how well the medication works for you.

Use in adolescents and children

The recommended starting dose for the treatment of schizophrenia in adolescents aged 15 years or older is 3 mg once a day taken in the morning.

For adolescents weighing 51 kg or more, the dose can be increased within the interval of 6 mg to 12 mg once a day.

For adolescents weighing less than 51 kg, the dose can be increased to 6 mg once a day.

Your doctor will decide how much to administer to you. The amount you take depends on how well the medication works for you.

How and when to take paliperidone cinfa

This medication should be taken by mouth, swallowed whole with water or other liquids. Do not chew, break, or crush it.

This medication should be taken in the mornings with breakfast or on an empty stomach, but in the same way every day. Do not alternate between taking the medication with breakfast and on an empty stomach the next day.

The active ingredient, paliperidone, dissolves once swallowed, and the coating of the tablet is eliminated from the body by the kidneys.

Patients with kidney problems

Your doctor may adjust the dose of this medication according to your kidney function.

Patients of advanced age

Your doctor may reduce your medication dose if your kidney function is reduced.

If you take more paliperidone cinfa than you should

In case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the Toxicological Information Service. Phone 91 562 04 20, indicating the medication and the amount ingested. You may experience drowsiness, dizziness, abnormal body movements, difficulty staying upright and walking, dizziness due to reduced blood pressure, and alterations in heartbeats.

If you forgot to take paliperidone cinfa

Do not take a double dose to compensate for the missed doses. If you forget a dose, take the next dose the next day. If you forget two or more doses, contact your doctor.

If you interrupt the treatment with paliperidone cinfa

Do not stop taking this medication as you will lose the effects of the medication. Do not stop taking this medication unless your doctor tells you to, as the symptoms may reappear.

If you have any other doubts about the use of this medication, ask your doctor or pharmacist.

Like all medicines, this medicine can cause side effects, althoughnotall people experience them.

Inform your doctor immediately if you experience any of the following:

- Blood clots in the veins, especially in the legs (symptoms include swelling, pain, and redness of the leg), which can travel through the blood vessels to the lungs causing chest pain and difficulty breathing. If you notice any of these symptoms, seek medical advice immediately.

- You have dementia and experience a sudden change in your mental state or sudden weakness or numbness in the face, arms, or legs, especially on one side, or you have trouble speaking even for a short period of time. These may be signs of a stroke.

- You experience fever, muscle stiffness, sweating, or a decrease in consciousness (a condition known as "Neuroleptic Malignant Syndrome"). You may need medical treatment.

- You are a man and experience a prolonged or painful erection. This is known as priapism. You may need medical treatment.

- You experience involuntary rhythmic movements of the tongue, mouth, and face. You may need to discontinue paliperidone.

- You experience a severe allergic reaction characterized by fever, swelling of the mouth, face, lips, or tongue, difficulty breathing, hives, skin rash, and sometimes a decrease in blood pressure (i.e., anaphylactic reaction).

Very common: may affect more than 1 in 10 patients

- Difficulty staying or remaining asleep.

- Parkinsonism: This disease may include slow or altered movement, a sensation of stiffness or tension in the muscles (making sudden movements) and sometimes a sensation of "freezing" of movement that is then reinitiated. Other signs of parkinsonism include walking slowly dragging the feet, trembling while descending stairs, increased saliva and/or drooling, and loss of facial expression.

- Incontinence.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

Common: may affect up to 1 in 10 patients

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Distonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- Dizziness.

- Restlessness.

- Difficulty concentrating, feeling drowsy or less attentive.

- Headache.

- Chest infection (bronchitis), common cold symptoms, nasal infection, urinary tract infection, feeling like you have a lump in your throat.

- Increased appetite, weight gain, weight loss, decreased appetite.

- Euphoria (mania), irritability, depression, anxiety.

- Dystonia: A disease that involves involuntary slow or continuous contraction of the muscles. Although it can affect any part of the body (and may cause abnormal postures), dystonia often affects the facial muscles, including abnormal movements of the eyes, mouth, tongue, or mandible.

- D

5. Conservation of paliperidone cinfa

6. Contents of the packaging and additional information