On this page
Medicines commonly prescribed for Reduced sex drive
For informational purposes only. Always consult a doctor before taking any medication.
Dosage form: CAPSULE, 20 mg fluoxetineActive substance: fluoxetineManufacturer: Kern Pharma S.L.Prescription requiredDosage form: TRANSDERMAL SOLUTION, 1.53 mg/sprayActive substance: estradiolManufacturer: Gedeon Richter Plc.Prescription requiredDosage form: TRANSDERMAL PATCH, 1.6 mg estradiol hemihydrateActive substance: estradiolManufacturer: Theramex Ireland LimitedPrescription required
Sex drive varies through life and there is no "normal" figure to measure yourself against. It becomes a reason to seek advice when the reduction troubles you or affects your relationship. There is rarely a single cause: physical, hormonal, medication-related and relationship factors usually combine, which is why the approach that works is the one that looks at all of them together.
Physical and hormonal causes
- low testosterone in men: accompanied by tiredness, loss of muscle mass and erectile problems;
- menopause and perimenopause: falling oestrogen causes vaginal dryness and discomfort, and pain reduces desire by a very direct route;
- childbirth and breastfeeding;
- thyroid disorders;
- raised prolactin;
- diabetes and cardiovascular disease;
- anaemia and iron deficiency;
- chronic pain and endometriosis;
- sleep apnoea and chronic sleep loss;
- obesity and inactivity;
- surgery or cancer treatment.
Medicines and substances
One of the commonest causes, and one of the least asked about.
- antidepressants, particularly selective serotonin reuptake inhibitors;
- antipsychotics;
- hormonal contraceptives, in some women;
- blood pressure medicines, especially beta blockers and diuretics;
- finasteride;
- anti-androgens and hormonal cancer treatments;
- opioids;
- heavy alcohol use and cannabis;
- anabolic steroids, which suppress the body's own testosterone production.
Psychological and relationship causes
- depression: loss of desire is part of the condition;
- anxiety and work stress;
- exhaustion and caring responsibilities;
- relationship conflict, accumulated resentment, poor communication;
- routine and lack of time alone together;
- fear of failure after an episode of difficulty;
- previous traumatic experiences;
- body image concerns;
- differences in desire between partners, which are often the real problem rather than either person's absolute level of desire.
When to see a doctor
- the reduction has lasted months and troubles you;
- it appeared abruptly;
- it comes with tiredness, weight gain or intolerance of cold;
- there are erectile problems or difficulty reaching orgasm;
- sex is painful;
- there is nipple discharge or irregular periods;
- it started after beginning a medicine: do not stop it yourself, discuss it with your doctor;
- there is low mood, general loss of interest or disturbed sleep;
- it is affecting your relationship;
- you take or have taken anabolic steroids.
How it is assessed
Conversation is the main part: how long it has been going on, whether it applies to every situation or only some, whether desire is present alone, and how sleep, mood and the relationship are. One useful pointer: if desire persists in other contexts, the cause is more likely to be relational or psychological than hormonal.
Blood tests depending on the case: morning total and free testosterone, LH, FSH, prolactin, oestradiol, thyroid function, full blood count, ferritin, glucose, lipid profile and vitamin D. A complete medication review is essential.
Treatment
- adjusting or changing the responsible medicine: this often resolves the problem;
- treating depression and anxiety, choosing drugs with less sexual impact;
- hormone replacement therapy in the menopause, and local oestrogen for vaginal dryness, which often transforms the experience;
- testosterone in men with a confirmed deficiency, and in selected women under specialist direction;
- treating the underlying condition: thyroid, prolactin, diabetes, anaemia, sleep apnoea;
- vaginal lubricants and moisturisers;
- sex and couple therapy: among the most effective approaches where the relationship component weighs heavily;
- treating pain if sex hurts: without that, no other treatment will work.
What you can do
- sleep 7–9 hours: sleep directly affects hormones and desire;
- regular physical activity;
- reduce alcohol and stop smoking;
- set aside unhurried time together without screens;
- talk about it with your partner without turning it into a reproach: most of the conflict here comes from silence;
- take the pressure off performance and rediscover physical contact without any expectation that it must lead anywhere;
- reduce your load and stress where possible;
- look at your relationship with your body image.
Common questions
How much desire is normal? There is no figure. What matters is whether it is a problem for you.
Is it just age? Desire usually declines gradually with age. A sudden drop is not explained by age and deserves investigation.
Do antidepressants always reduce it? Not all of them, and there are alternatives and adjustments. Never stop them on your own.
Is testosterone the answer? Only if there is a genuine deficiency confirmed by blood tests. Taking it without a deficiency does not increase desire and suppresses your own production.
What if my partner and I have different levels of desire? This is very common and does not mean either of you is "wrong". It is better worked on as a couple than individually.
Online consultation
In an online consultation the doctor separates the physical causes from the relational ones, reviews your medication thoroughly, advises which hormone tests make sense and when to take them, assesses mood and sleep, and advises when adding sex or couple therapy is worthwhile.
This material is for information only and does not replace a medical consultation.
Medically reviewed by
Reviewed on Jul 6, 2026
Online doctors for Reduced sex drive
Discuss your symptoms and possible next steps for Reduced sex drive with a doctor online.














