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XILONIBSA 10 mg /Puff Topical Solution

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Doctor
5.0(16)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
This page is for general information. Consult a doctor for personal advice. Call emergency services if symptoms are severe.
About the medicine

How to use XILONIBSA 10 mg/puff, cutaneous spray solution

Contents of the leaflet

  1. Introduction
  2. What Xilonibsa 10 mg/spray is and what it is used for
  3. What you need to know before starting to use Xilonibsa 10 mg/spray
  4. How to use Xilonibsa 10 mg/spray
  5. Possible side effects
  6. Storage of Xilonibsa 10 mg/spray
  7. Package contents and additional information

Introduction

Leaflet: information for the user

Xilonibsa 10 mg/spray, solution for cutaneous spraying

Lidocaine

Read this leaflet carefully before starting to use this medicine, as it contains important information for you.

  • Keep this leaflet, as you may need to read it again.
  • If you have any questions, consult your doctor.
  • This medicine has been prescribed to you only, and you should not give it to others, even if they have the same symptoms as you, as it may harm them.
  • If you experience side effects, consult your doctor, even if they are not listed in this leaflet. See section 4.

Contents of the leaflet

  1. What Xilonibsa 10 mg/spray is and what it is used for
  2. What you need to know before starting to use Xilonibsa 10 mg/spray
  3. How to use Xilonibsa 10 mg/spray
  4. Possible side effects
  5. Storage of Xilonibsa 10 mg/spray
  6. Package contents and additional information

1. What Xilonibsa 10 mg/spray is and what it is used for

Xilonibsa 10 mg/spray contains lidocaine and belongs to the group of local anesthetics of the amide type.

Xilonibsa 10 mg/spray is indicated for superficial anesthesia of the mucosa in surgery, obstetrics, dentistry, and otorhinolaryngology.

Doctor consultation

Not sure if this medicine is right for you?

Discuss your symptoms and treatment with a doctor online.

2. What you need to know before starting to use Xilonibsa 10 mg/spray

Do not use Xilonibsa 10 mg/spray:

  • if you are allergic to lidocaine or to anesthetics of the amide type or to any of the other components of this medicine (listed in section 6).

Warnings and precautions

Consult your doctor before starting to take Xilonibsa 10 mg/spray:

  • if you are an elderly and debilitated person.
  • if you suffer from epilepsy, hypovolemia, atrioventricular block, or other conduction disorders.
  • if you have bradycardia or impaired respiratory function.
  • if you have impaired liver function.
  • if you suffer from heart and circulatory failure.
  • if you suffer from renal impairment.

Excessive doses should be avoided, as well as the application of the medicine to infected or inflamed tissues, as the absorption of lidocaine is very rapid in these cases, and systemic adverse reactions may occur.

Eye contact with lidocaine should be avoided. In case of eye contact, if necessary, remove the contact lenses from the person. Wash immediately and abundantly with water for 15 minutes, keeping the eyelids apart. Do not let the water flow towards the unaffected eye. Perform immediate complementary treatments with an ophthalmologist.

Patients being treated with antiarrhythmic drugs of class III (e.g., amiodarone) should be closely monitored and electrocardiogram (ECG) monitoring should be considered, as cardiac effects may be additive.

Children

Xilonibsa 10 mg/spray is not recommended for use in children under 6 years of age due to the risk of rapid absorption of the anesthetic and the risk of reflex laryngospasm in the newborn.

Lidocaine should be used with caution in children over 6 years of age, not exceeding the maximum recommended dose.

Taking Xilonibsa 10 mg/spray with other medicines

Tell your doctor if you are using, have recently used, or may need to use any other medicine.

In particular, inform your doctor if you have recently used or have received treatment with any of the following medicines:

  • Medicines used to treat epilepsy, such as phenytoin.
  • Medicines used to treat AIDS (atazanavir, darunavir).
  • Other local or general anesthetics (halothane).
  • Diuretic medicines (acetazolamide, loop diuretics, and thiazides).
  • Cimetidine or beta-blockers.

Using Xilonibsa 10 mg/spray with food and drinks

It is recommended not to ingest food or liquids until sensitivity is regained to prevent the risk of biting in the mouth.

Pregnancy, breastfeeding, and fertility

If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, consult your doctor before using this medicine.

Pregnancy

Xilonibsa 10 mg/spray is not recommended during pregnancy, as it crosses the placental barrier. However, no evidence of congenital anomalies has been demonstrated.

The use of Xilonibsa 10 mg/spray during pregnancy will be reserved only for those cases where the potential benefit justifies the possible risks to the fetus.

Breastfeeding

Xilonibsa 10 mg/spray is excreted in breast milk, but at therapeutic doses used, no effects are expected in newborns/children during breastfeeding.

Fertility

No effects on fertility have been reported with Xilonibsa 10 mg/spray.

Driving and using machines

The influence of Xilonibsa 10 mg/spray on the ability to drive and use machines is small.

Depending on the dose and place of administration, local anesthetics may affect mental function and temporarily alter locomotion and coordination. When administering this medicine, the doctor should assess each particular case to determine if the reaction capacity is compromised and if the patient can drive or use machines.

Xilonibsa 10 mg/spray may cause dizziness, sedation, blurred vision, and dizziness. If any of these side effects occur after applying Xilonibsa 10 mg/spray, you should wait until they cease before driving or using machinery.

Xilonibsa 10 mg/spray contains ethanol

This medicine contains 241 mg of alcohol (ethanol) per ml. It may cause a burning sensation on damaged skin.

3. How to use Xilonibsa 10 mg/spray

Xilonibsa 10 mg/spray will be administered by your doctor.

The lowest dose that provides the required anesthetic effect should be administered, avoiding excessive doses.

No more than 20 sprays should be applied to produce the desired anesthesia in adults.

In dentistry

It is recommended to administer 1 to 5 applications to the mucosa.

In otorhinolaryngology

When used for maxillary sinus puncture, it is recommended to apply 3 sprays.

In gynecology-obstetrics

It is recommended to apply approximately 20 sprays (equivalent to 200 mg).

Keep in mind that the maximum dose in 24 hours for an adult weighing approximately 70 kg is 200 mg (corresponding to 20 applications with the dosing valve). No more than 20 applications should be administered per adult patient. If dosing is based on patient weight, the dose should not exceed 3 mg/kg body weight per day.

Use in children

The dose of lidocaine in children should be adjusted according to the nature of the procedure and the patient's characteristics. In children over 6 years of age, the maximum dose will be calculated based on body weight, taking the dose of 3 mg/kg body weight per day as the maximum recommended daily dose.

Xilonibsa 10 mg/spray is not recommended for use in children under 6 years of age.

If you use more Xilonibsa 10 mg/spray than you should

As with other local anesthetics, due to excessive dosing or rapid absorption, systemic reactions may occur that can affect the central nervous system and the cardiovascular system. In these cases, treatment will consist of maintaining vital signs, and if convulsions appear, administering short-acting barbiturates (such as thiopental) or benzodiazepines (diazepam) intravenously.

In case of overdose or accidental ingestion, consult the Toxicological Information Service. Telephone 91 562 04 20.

Medicine questions

Started taking the medicine and have questions?

Discuss your symptoms and treatment with a doctor online.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everyone gets them.

Xilonibsa 10 mg/spray may cause local irritation (coughing, sneezing) at the time of application or immediately after.

Other adverse reactions that may be observed with the use of this medicine are:

Rare side effects (may affect up to 1 in 1000 patients).

Cardiac disorders: Hypotension, arrhythmias, bradycardia, cardiovascular arrest.

Nervous system disorders: Metallic taste, tinnitus, dizziness, nausea, vomiting, anxiety, tremors, nystagmus, headache, increased respiratory rate, paresthesia (loss of sensitivity accompanied by burning) of the lip and/or tongue, unconsciousness, and convulsions, coma, and respiratory arrest (in case of overdose).

Respiratory disorders: Tachypnea followed by bradypnea, which may cause apnea.

Very rare side effects (may affect up to 1 in 10,000 patients).

General disorders and administration site conditions:Allergic reactions, skin rash, erythema, pruritus, edema of the tongue, mouth, lips, or throat, and, in severe cases, anaphylactic shock.

Reporting side effects

If you experience any side effects, consult your doctor, even if they are not listed in this leaflet. You can also report them directly through the Spanish Medicines and Healthcare Products Agency (AEMPS) website: www.notificaram.es. By reporting side effects, you can help provide more information on the safety of this medicine.

5. Storage of Xilonibsa 10 mg/spray

Keep this medicine out of the sight and reach of children.

Do not store above 25°C.

Keep in the original packaging to protect from light.

Do not use this medicine after the expiration date stated on the packaging. The expiration date is the last day of the month indicated.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and any unused medicines. This will help protect the environment.

6. Package contents and additional information

Composition of Xilonibsa 10 mg/spray

  • The active ingredient is lidocaine.
  • The other excipients are ethanol 96%, menthol, saccharin, macrogol 400, banana flavor, and purified water.

Appearance of the product and package contents

Xilonibsa 10 mg/spray is a clear or practically clear solution with a characteristic odor.

Xilonibsa 10 mg/spray is presented in a 50 ml bottle containing approximately 500 sprays. Each bottle contains a dosing valve that provides a dose of 10 mg of lidocaine per spray.

Marketing authorization holder and manufacturer

Laboratorios Inibsa, S.A.

Ctra. Sabadell a Granollers, km. 14,5

08185 Lliçà de Vall (Barcelona)

Spain

Telephone: +34 938 609 500

Fax: +34 938 439 695

e-mail: [email protected]

Local representative

LAPHYSAN S.A.U.

Anabel Segura, 11 Edificio A, Planta 4, Puerta D

28108 Alcobendas (Madrid)

Spain

Date of the last revision of this leaflet: May 2016

Detailed information about this medicine is available on the website of the Spanish Agency for Medicines and Healthcare Products (AEMPS) http://www.aemps.gob.es/

Online doctors for XILONIBSA 10 mg/puff, cutaneous spray solution

Discuss questions about XILONIBSA 10 mg/puff, cutaneous spray solution, including use, safety considerations and prescription review, subject to medical assessment and local regulations.

Doctor
5.0(16)

Sergey Ilyasov

PsychiatryNeurology7 years of experience

Dr Sergey Ilyasov is an experienced neurologist and qualified psychiatrist who provides online consultations for adults and adolescents. Combining deep neurological expertise with a modern psychiatric approach, he ensures comprehensive diagnostics and effective treatment for a wide range of conditions affecting both physical and mental health.

Dr. Ilyasov helps patients in the following cases:

  • Chronic headaches (migraine, tension-type headache), back pain, neuropathic pain, dizziness, numbness in limbs, coordination disorders.
  • Anxiety disorders (panic attacks, generalized anxiety disorder), depression (including atypical and treatment-resistant forms), sleep disturbances (insomnia, hypersomnia, nightmares), stress, burnout.
  • Chronic pain syndromes and psychosomatic symptoms (e.g., irritable bowel syndrome related to stress, vegetative-vascular dystonia).
  • Behavioral disorders and concentration difficulties in adolescents (including ADHD, autism spectrum disorders), nervous tics.
  • Memory impairments, phobias, obsessive-compulsive disorder (OCD), emotional swings, and support for post-traumatic stress disorder (PTSD).

Thanks to his dual specialization in neurology and psychiatry, Dr Sergey Ilyasov offers integrated and evidence-based care for complex conditions requiring a multidisciplinary approach. His consultations focus on accurate diagnosis, development of an individualized treatment plan (including pharmacotherapy and psychotherapeutic methods), and long-term support adapted to each patient's unique needs.

Book an online consultation with Dr. Sergey Ilyasov to receive qualified assistance and improve your well-being today.

Book a video appointment
€106
Doctor
5.0(38)

Andrei Popov

General medicinePain medicine7 years of experience

Dr. Andrei Popov is a General Practitioner with specialized training in chronic pain. He provides online consultations for adult patients in Spain and other European countries.

Dr. Popov understands that seeking help with weight-related concerns or pain that has persisted for months can be difficult. Many patients come to him after trying different approaches without feeling truly heard. During the consultation, the doctor creates a comfortable and supportive, non-judgmental environment where the patient’s medical history can be discussed in detail, questions can be answered, and the next steps can be decided together.

Weight Management and Metabolic Health

Dr. Popov can help assess overweight, obesity, and related conditions such as hypertension, diabetes, or metabolic disorders. During the consultation, the patient’s medical history, test results, current medications, and previous treatments will be reviewed.

If you would like to learn about possible medication options or have already started treatment, the doctor can assess your situation, review the effectiveness and tolerability of the therapy, and clearly explain its benefits, potential risks, and alternatives.

Not every patient requires the same treatment. A consultation does not guarantee a prescription — it provides an objective medical assessment and a plan tailored to your individual situation.

Pain and General Medicine

You can also consult Dr. Popov regarding:

* chronic pain, migraines, neuralgia, and fibromyalgia;

* back, neck, lower back, or joint pain;

* hypertension, diabetes, and follow-up of chronic conditions;

* review of test results, medical reports, and current treatment;

* preventive medicine and a second medical opinion.

How the Consultation Works

The video consultation lasts up to 30 minutes. The doctor will listen carefully, review the information you provide, and explain the next steps in clear and understandable language.

If additional tests, an in-person consultation, or urgent medical care are required, the doctor will inform you directly.

Dr. Popov’s goal is to make sure the patient feels heard and leaves the consultation with a clear understanding of their condition and the next steps they can take.

Book a video appointment
€86
Doctor
5.0(12)

Yevgen Yakovenko

General medicine12 years of experience

Dr. Yevgen Yakovenko is a licensed surgeon and general practitioner in Spain and Germany. He specialises in general, paediatric, and oncological surgery, internal medicine, and pain management. He offers online consultations for adults and children, combining surgical precision with therapeutic support. Dr Yakovenko works with patients across different countries and provides care in Ukrainian, Russian, English, and Spanish.

Areas of medical expertise:

  • Acute and chronic pain: headaches, muscle and joint pain, back pain, abdominal pain, postoperative pain. Identifying the cause, selecting treatment, and creating a care plan.
  • Internal medicine: heart, lungs, gastrointestinal tract, urinary system. Management of chronic conditions, symptom control, second opinions.
  • Pre- and postoperative care: risk assessment, decision-making support, follow-up after surgery, rehabilitation strategies.
  • General and paediatric surgery: hernias, appendicitis, congenital conditions, both planned and urgent surgeries.
  • Injuries and trauma: bruises, fractures, sprains, soft tissue damage, wound care, dressing, referral when in-person care is required.
  • Oncological surgery: diagnosis review, treatment planning, and long-term follow-up.
  • Obesity treatment and weight management: a medical approach to weight loss, including assessment of underlying causes, evaluation of comorbidities, development of a personalised plan (nutrition, physical activity, pharmacotherapy if needed), and ongoing progress monitoring.
  • Imaging interpretation: analysis of ultrasound, CT, MRI, and X-ray results, surgical planning based on imaging data.
  • Second opinions and medical navigation: clarifying diagnoses, reviewing current treatment plans, helping patients choose the best course of action.

Experience and qualifications:

  • 12+ years of clinical experience in university hospitals in Germany and Spain.
  • International education: Ukraine – Germany – Spain.
  • Member of the German Society of Surgeons (BDC).
  • Certified in radiological diagnostics and robotic surgery.
  • Active participant in international medical conferences and research.

Dr Yakovenko explains complex topics in a clear, accessible way. He works collaboratively with patients to analyse health issues and make evidence-based decisions. His approach is grounded in clinical excellence, scientific accuracy, and respect for each individual.

If you are unsure about a diagnosis, preparing for surgery, or want to discuss your test results – Dr Yakovenko will help you evaluate your options and move forward with confidence.

Book a video appointment
€72
Doctor
5.0(24)

Taisiia Proida

Psychiatry7 years of experience

Taisiia Proida is a general practitioner with a specialization in mental health and a cognitive behavioral therapist (CBT), a member of the European Psychiatric Association. She offers online consultations for adults aged 18 and over, combining evidence-based medicine with an individualised approach to mental health care. She specialises in consultations and ongoing support for a wide range of mental health concerns, including: 

  • Mood disorders: depression, bipolar disorder, postpartum depression.
  • Anxiety disorders: generalised anxiety, OCD, panic attacks, phobias.
  • Post-traumatic stress disorder (PTSD) and complex PTSD.
  • Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Assessment is provided only after an initial psychiatric evaluation and during a follow-up appointment.
  • Personality disorders and emotional instability.
  • Cyclothymia and mood fluctuations.
  • Schizophrenia spectrum and related conditions.

Dr. Proida combines clinical expertise with an empathetic approach, offering structured support based on evidence-based practices. Her work integrates CBT techniques with medical management, with a focus on anxiety and depressive disorders. She works with clients from different countries and cultural backgrounds, adapting her communication style and recommendations to individual needs. With experience in international clinical trials (Pfizer, Merck), she values clarity, trust, and collaborative partnership in patient care.

Book a video appointment
€156
Doctor
5.0(3)

Lina Travkina

General medicine13 years of experience

Dr. Lina Travkina is a licensed family and preventive medicine doctor based in Italy. She provides online consultations for adults and children, supporting patients across all stages of care – from acute symptom management to long-term health monitoring and prevention.Areas of medical care include:

  • Respiratory conditions: colds, flu, acute and chronic bronchitis, mild to moderate pneumonia, bronchial asthma.

  • ENT and eye conditions: sinusitis, tonsillitis, pharyngitis, otitis, infectious and allergic conjunctivitis.

  • Digestive issues: gastritis, acid reflux (GERD), IBS, dyspepsia, bloating, constipation, diarrhoea, functional bowel symptoms, intestinal infections.

  • Urological and infectious diseases: acute and recurrent cystitis, bladder and kidney infections, prevention of recurrent UTIs, asymptomatic bacteriuria.

  • Chronic conditions: hypertension, diabetes, hypercholesterolemia, metabolic syndrome, thyroid disorders, excess weight.

  • Neurological and general symptoms: headache, migraine, dizziness, fatigue, sleep disturbances, reduced concentration, anxiety, asthenia.

  • Chronic pain support: back, neck, joint, and muscle pain, tension syndromes, pain associated with osteochondrosis and chronic conditions.

Additional care areas:

  • Preventive consultations and check-up planning.

  • Medical advice and follow-up consultations.

  • Test interpretation and diagnostic guidance.

  • Structured support for undiagnosed complaints.

  • Second opinion on diagnoses and treatment plans.

  • Nutritional and lifestyle support for vitamin deficiencies, anaemia, metabolic issues.

  • Post-operative recovery support and pain management.

  • Preconception counselling and postpartum support.

  • Immunity support and strategies to reduce frequency of infections.

Dr. Travkina combines evidence-based medicine with an attentive, personalised approach. Her consultations focus not only on treatment, but also on prevention, recovery, and long-term wellbeing.If during the consultation it becomes clear that your case requires in-person assessment or specialised care outside of her scope, the session will be terminated and the payment fully refunded.

Book a video appointment
€75
Doctor
5.0(21)

Nuno Tavares Lopes

General medicine18 years of experience

Dr. Nuno Tavares Lopes is a licensed physician in Portugal with 17 years of experience in emergency medicine, family and general practice, and public health. He is the Director of Medical and Public Health Services at an international healthcare network and serves as an external consultant for the WHO and ECDC.

  • Emergency care: infections, fever, chest/abdominal pain, minor injuries, paediatric emergencies

  • Family medicine: hypertension, diabetes, cholesterol, chronic disease management

  • Travel medicine: pre-travel advice, vaccinations, fit-to-fly certificates, travel-related illnesses

  • Sexual and reproductive health: PrEP, STD prevention, counselling, treatment

  • Weight management and wellness: personalised weight loss programmes, lifestyle guidance

  • Skin and ENT issues: acne, eczema, allergies, rashes, sore throat, sinusitis

  • Pain management: acute and chronic pain, post-surgical care

  • Public health: prevention, health screenings, long-term monitoring

  • Sick leave (Baixa médica) connected to Segurança Social in Portugal

  • IMT medical certificates for driving licence exchange

Dr. Nuno Tavares Lopes provides medical support for patients using GLP-1 medications (Mounjaro, Wegovy, Ozempic, Rybelsus) as part of a weight loss strategy. He offers individualised treatment planning, regular follow-up, dose adjustment, and advice on combining medication with sustainable lifestyle changes. Consultations follow the medical standards accepted in Europe.Dr. Lopes also provides interpretation of medical tests, follow-up care for complex patients, and multilingual support. Whether for urgent concerns or long-term care, he helps patients act with clarity and confidence.

Book a video appointment
€70

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Frequently Asked Questions

XILONIBSA 10 mg/puff, cutaneous spray solution requires a prescription in Spain. You can check with a doctor online whether this medicine may be appropriate for your situation.

The active ingredient in XILONIBSA 10 mg/puff, cutaneous spray solution is lidocaine. This information helps identify medicines with the same composition but different brand names.

XILONIBSA 10 mg/puff, cutaneous spray solution is manufactured by Laboratorios Inibsa S.A.. Pharmacy brands and packaging may differ depending on the distributor.

Doctors such as Family doctors, Psychiatrists, Dermatologists, Cardiologists, Endocrinologists, Gastroenterologists, Pulmonologists, Nephrologists, Rheumatologists, Hematologists, Infectious disease physicians, Allergists, Geriatricians, Paediatricians, Oncologists may assess whether XILONIBSA 10 mg/puff, cutaneous spray solution is appropriate, depending on your situation and local regulations. You can book an online consultation to discuss your symptoms and possible next steps.

Spain has a well-developed healthcare infrastructure across major cities such as Madrid, Barcelona, Valencia, and Seville. Pharmacies are widely available and operate under strict regulations, ensuring access to prescribed medications.

You can buy XILONIBSA 10 mg/puff, cutaneous spray solution in Madrid, Barcelona, Seville, or Valencia at any local pharmacy with a valid prescription.

To obtain a prescription, you can use Oladoctor:

Other medicines with the same active substance (lidocaine) include ACTILOGIC 700 MG MEDICATED ADHESIVE DRESSING, DYNEXAN 20 mg/g BUCAL GEL, INSTILLIDO 20 mg/ml GEL. These may have different brand names or formulations but contain the same therapeutic ingredient. Always consult a doctor before switching or starting a new medicine.

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